MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 145449 bp
Accession: NZ_CP035258 Location: 930362..1075810 Organism: Streptococcus pneumoniae strain TVO_1901927 Replicon: chromosome
Accession: NZ_CP035258 Location: 930362..1075810 Organism: Streptococcus pneumoniae strain TVO_1901927 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQH22_RS04665 (EQH22_04940) | 925599..926822 | - | 1224 | WP_000222046.1 | peptidase T | - |
| EQH22_RS04670 (EQH22_04945) | 926977..928071 | + | 1095 | WP_000709247.1 | ferrochelatase | - |
| EQH22_RS04675 (EQH22_04950) | 928113..928490 | - | 378 | WP_000916795.1 | large conductance mechanosensitive channel protein MscL | - |
| EQH22_RS04680 (EQH22_04955) | 928572..929003 | - | 432 | WP_054362861.1 | GtrA family protein | - |
| EQH22_RS04685 (EQH22_04960) | 929126..929635 | + | 510 | WP_000737071.1 | QueT transporter family protein | - |
| EQH22_RS04695 (EQH22_04975) | 930393..931469 | + | 1077 | WP_000542471.1 | aspartate-semialdehyde dehydrogenase | - |
| EQH22_RS04700 (EQH22_04980) | 931525..932460 | + | 936 | WP_000121627.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| EQH22_RS04705 (EQH22_04985) | 932507..933880 | - | 1374 | WP_000632719.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| EQH22_RS04710 (EQH22_04990) | 934017..934199 | - | 183 | WP_001117401.1 | 4-oxalocrotonate tautomerase | - |
| EQH22_RS04715 (EQH22_04995) | 934322..934921 | + | 600 | WP_000068153.1 | thymidine kinase | - |
| EQH22_RS04720 (EQH22_05000) | 934911..935390 | + | 480 | WP_000151335.1 | GNAT family N-acetyltransferase | - |
| EQH22_RS04725 (EQH22_05005) | 935400..936479 | + | 1080 | WP_001028801.1 | peptide chain release factor 1 | - |
| EQH22_RS04730 (EQH22_05010) | 936479..937318 | + | 840 | WP_000761916.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| EQH22_RS04735 (EQH22_05015) | 937302..937904 | + | 603 | WP_000990345.1 | L-threonylcarbamoyladenylate synthase | - |
| EQH22_RS04740 (EQH22_05020) | 937906..938337 | + | 432 | WP_000942936.1 | GNAT family N-acetyltransferase | - |
| EQH22_RS04745 (EQH22_05025) | 938399..939655 | + | 1257 | WP_000575522.1 | serine hydroxymethyltransferase | - |
| EQH22_RS04750 (EQH22_05030) | 939663..940637 | + | 975 | WP_000356094.1 | nucleoid-associated protein | - |
| EQH22_RS04755 (EQH22_05035) | 940637..941251 | + | 615 | WP_000476384.1 | cell wall hydrolase Pmp23 | - |
| EQH22_RS04760 (EQH22_05040) | 941325..942299 | + | 975 | WP_001227738.1 | DUF1002 domain-containing protein | - |
| EQH22_RS04765 (EQH22_05045) | 942373..943998 | + | 1626 | WP_000914568.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| EQH22_RS04770 (EQH22_05050) | 944212..944490 | + | 279 | WP_000710807.1 | hypothetical protein | - |
| EQH22_RS04775 (EQH22_05055) | 944736..944954 | + | 219 | WP_001207345.1 | helix-turn-helix transcriptional regulator | - |
| EQH22_RS04780 (EQH22_05065) | 945347..946372 | + | 1026 | WP_000790743.1 | ABC transporter substrate-binding protein | - |
| EQH22_RS04785 (EQH22_05070) | 946362..947369 | + | 1008 | WP_001244693.1 | Vitamin B12 import system permease protein BtuC | VF |
| EQH22_RS04790 (EQH22_05075) | 947369..948376 | + | 1008 | WP_001180361.1 | Vitamin B12 import system permease protein BtuC | VF |
| EQH22_RS04795 (EQH22_05080) | 948376..949170 | + | 795 | WP_000677520.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| EQH22_RS04800 | 949321..949505 | + | 185 | Protein_956 | IS3 family transposase | - |
| EQH22_RS04805 (EQH22_05085) | 949558..949983 | + | 426 | WP_074192621.1 | restriction endonuclease subunit S | - |
| EQH22_RS04810 (EQH22_05090) | 950039..950356 | + | 318 | WP_000968321.1 | DUF3847 domain-containing protein | - |
| EQH22_RS04815 | 950670..951104 | + | 435 | Protein_959 | IS1380 family transposase ISSpn5 | Transposase |
| EQH22_RS04820 (EQH22_05095) | 951327..952673 | + | 1347 | WP_001811769.1 | IS1380 family transposase ISSpn5 | Transposase |
| EQH22_RS04825 (EQH22_05100) | 952864..954018 | + | 1155 | Protein_961 | MobA/MobL family protein | - |
| EQH22_RS04830 (EQH22_05105) | 954400..954927 | + | 528 | WP_000606578.1 | PcfB family protein | - |
| EQH22_RS04835 (EQH22_05110) | 955054..955782 | + | 729 | WP_000224685.1 | phage replisome organizer N-terminal domain-containing protein | - |
| EQH22_RS04840 (EQH22_05115) | 956466..956627 | + | 162 | WP_000368174.1 | hypothetical protein | - |
| EQH22_RS04845 (EQH22_05120) | 956719..958398 | + | 1680 | WP_000031842.1 | Tn3 family transposase TnpR_ISAcsp1 | Transposase |
| EQH22_RS04850 (EQH22_05125) | 958666..959232 | + | 567 | WP_000234983.1 | hypothetical protein | - |
| EQH22_RS04855 (EQH22_05130) | 959553..959741 | + | 189 | WP_000179769.1 | hypothetical protein | - |
| EQH22_RS04860 (EQH22_05135) | 959803..960561 | + | 759 | WP_000262042.1 | ATP-grasp domain-containing protein | - |
| EQH22_RS04865 (EQH22_05140) | 960619..961473 | + | 855 | WP_000900020.1 | ADP-ribosylglycohydrolase family protein | - |
| EQH22_RS04870 (EQH22_05145) | 961585..962469 | + | 885 | WP_000710115.1 | diacylglycerol kinase family lipid kinase | - |
| EQH22_RS04875 (EQH22_05155) | 962632..964250 | + | 1619 | Protein_971 | glycoside hydrolase family 13 protein | - |
| EQH22_RS04880 (EQH22_05160) | 964525..964980 | + | 456 | WP_000500474.1 | hypothetical protein | - |
| EQH22_RS04885 (EQH22_05165) | 965425..965901 | + | 477 | WP_000579613.1 | type II toxin-antitoxin system antitoxin PezA | Antitoxin Detail |
| EQH22_RS04890 (EQH22_05170) | 965901..966662 | + | 762 | WP_000405362.1 | type II toxin-antitoxin system toxin PezT | Toxin Detail |
| EQH22_RS04895 | 966690..966980 | + | 291 | WP_001213954.1 | hypothetical protein | - |
| EQH22_RS04900 | 966974..967846 | + | 873 | WP_001811494.1 | hypothetical protein | - |
| EQH22_RS04905 (EQH22_05185) | 968665..969024 | + | 360 | WP_000003750.1 | SAG1252 family conjugative relaxosome accessory protein | - |
| EQH22_RS04910 (EQH22_05190) | 969034..969399 | + | 366 | WP_000263054.1 | plasmid mobilization relaxosome protein MobC | - |
| EQH22_RS04915 (EQH22_05195) | 969386..971236 | + | 1851 | WP_000261801.1 | SAG1250 family conjugative relaxase | - |
| EQH22_RS04920 (EQH22_05200) | 971492..972924 | + | 1433 | Protein_980 | IS1182 family transposase | - |
| EQH22_RS04925 (EQH22_05210) | 973823..974122 | + | 300 | WP_001138382.1 | hypothetical protein | - |
| EQH22_RS04930 (EQH22_05215) | 974181..974855 | + | 675 | WP_000903082.1 | CatA-like O-acetyltransferase | - |
| EQH22_RS04935 (EQH22_05220) | 974923..976560 | + | 1638 | WP_000021543.1 | methionine--tRNA ligase | - |
| EQH22_RS04940 (EQH22_05225) | 976661..977428 | + | 768 | Protein_984 | tyrosine-protein phosphatase | - |
| EQH22_RS04945 (EQH22_05230) | 978445..979437 | + | 993 | WP_024266136.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| EQH22_RS04950 (EQH22_05235) | 979439..980257 | + | 819 | WP_000164265.1 | ABC-2 family transporter protein | - |
| EQH22_RS04955 (EQH22_05240) | 980259..981044 | + | 786 | WP_000760754.1 | ABC transporter permease | - |
| EQH22_RS04960 (EQH22_05245) | 981423..982673 | - | 1251 | Protein_988 | IS110 family transposase | - |
| EQH22_RS04965 (EQH22_05250) | 983120..983323 | + | 204 | WP_000275922.1 | helix-turn-helix transcriptional regulator | - |
| EQH22_RS04970 | 983454..983606 | + | 153 | WP_001812617.1 | hypothetical protein | - |
| EQH22_RS04975 (EQH22_05255) | 983773..985566 | + | 1794 | WP_054362863.1 | hypothetical protein ; Integrase | Integrase |
| EQH22_RS04980 (EQH22_05260) | 985650..986258 | + | 609 | WP_000662946.1 | Type 1 glutamine amidotransferase-like domain-containing protein | - |
| EQH22_RS04985 (EQH22_05265) | 986510..986788 | + | 279 | WP_001843523.1 | aminoglycoside phosphotransferase | - |
| EQH22_RS04990 (EQH22_05270) | 986893..987222 | + | 330 | Protein_994 | IS5 family transposase IS1381A | Transposase |
| EQH22_RS04995 (EQH22_05275) | 987350..988579 | + | 1230 | WP_000703362.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| EQH22_RS05000 (EQH22_05280) | 988599..991295 | + | 2697 | WP_000058204.1 | phosphoenolpyruvate carboxylase | - |
| EQH22_RS05005 (EQH22_05285) | 991708..992712 | + | 1005 | WP_000792163.1 | hypothetical protein | VF |
| EQH22_RS05010 (EQH22_05290) | 992781..993647 | + | 867 | WP_000637234.1 | ABC transporter permease | - |
| EQH22_RS05015 (EQH22_05295) | 993644..994402 | + | 759 | WP_000125400.1 | ABC transporter ATP-binding protein | - |
| EQH22_RS05020 (EQH22_05300) | 994492..996252 | + | 1761 | WP_000227896.1 | DNA primase | - |
| EQH22_RS05025 (EQH22_05305) | 996255..997364 | + | 1110 | WP_000201898.1 | RNA polymerase sigma factor RpoD | - |
| EQH22_RS05030 (EQH22_05310) | 997378..997707 | + | 330 | WP_000331928.1 | metal-sulfur cluster assembly factor | - |
| EQH22_RS05035 (EQH22_05315) | 997822..998865 | + | 1044 | WP_000412279.1 | alpha-galactosylglucosyldiacylglycerol synthase | - |
| EQH22_RS05040 (EQH22_05320) | 998881..1000206 | + | 1326 | WP_001219434.1 | glycosyltransferase family 4 protein | - |
| EQH22_RS05045 (EQH22_05325) | 1000237..1000413 | + | 177 | WP_001256250.1 | PspC domain-containing protein | - |
| EQH22_RS05050 (EQH22_05330) | 1000472..1000606 | + | 135 | WP_000863859.1 | DUF4044 domain-containing protein | - |
| EQH22_RS05055 (EQH22_05335) | 1000670..1001980 | + | 1311 | WP_000061646.1 | GTPase ObgE | - |
| EQH22_RS05060 (EQH22_05340) | 1001990..1002148 | + | 159 | WP_001808548.1 | hypothetical protein | - |
| EQH22_RS05065 (EQH22_05345) | 1002200..1003526 | - | 1327 | Protein_1009 | ISL3 family transposase | - |
| EQH22_RS05070 (EQH22_05350) | 1004702..1005961 | + | 1260 | WP_001227083.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| EQH22_RS05075 (EQH22_05355) | 1005977..1006528 | + | 552 | WP_001103684.1 | GNAT family N-acetyltransferase | - |
| EQH22_RS05080 (EQH22_05360) | 1006521..1007798 | + | 1278 | WP_000033830.1 | CBS-HotDog domain-containing transcription factor SpxR | - |
| EQH22_RS05085 (EQH22_05365) | 1007814..1008674 | + | 861 | WP_000631543.1 | methionyl aminopeptidase | - |
| EQH22_RS05090 (EQH22_05375) | 1009055..1009859 | + | 805 | WP_137997052.1 | IS5 family transposase | - |
| EQH22_RS05095 (EQH22_05380) | 1010051..1012342 | + | 2292 | WP_054362865.1 | DNA helicase PcrA | - |
| EQH22_RS05100 (EQH22_05385) | 1012385..1013065 | + | 681 | WP_000286922.1 | DNA repair protein RadC | - |
| EQH22_RS05105 (EQH22_05390) | 1013062..1013751 | - | 690 | WP_000743316.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| EQH22_RS05110 (EQH22_05395) | 1013769..1014410 | - | 642 | WP_000653403.1 | redox-sensing transcriptional repressor Rex | - |
| EQH22_RS05115 (EQH22_05400) | 1014493..1014708 | - | 216 | WP_000462487.1 | DUF4649 family protein | - |
| EQH22_RS05120 (EQH22_05405) | 1014716..1015063 | - | 348 | WP_000863509.1 | DUF1831 domain-containing protein | - |
| EQH22_RS05125 (EQH22_05410) | 1015068..1016183 | - | 1116 | WP_000639664.1 | cysteine desulfurase family protein | - |
| EQH22_RS05130 (EQH22_05415) | 1016193..1017152 | - | 960 | WP_001283813.1 | ribose-phosphate diphosphokinase | - |
| EQH22_RS05135 (EQH22_05420) | 1017265..1017834 | - | 570 | WP_238115218.1 | CYTH domain-containing protein | - |
| EQH22_RS05140 (EQH22_05425) | 1017962..1018633 | + | 672 | WP_000171676.1 | GTP pyrophosphokinase family protein | - |
| EQH22_RS05145 (EQH22_05430) | 1018617..1019435 | + | 819 | WP_000799053.1 | NAD kinase | - |
| EQH22_RS05150 (EQH22_05435) | 1019432..1020328 | + | 897 | WP_001210004.1 | RluA family pseudouridine synthase | - |
| EQH22_RS05155 (EQH22_05440) | 1020372..1021346 | + | 975 | WP_000451586.1 | phosphate acetyltransferase | - |
| EQH22_RS05160 (EQH22_05445) | 1021687..1021986 | - | 300 | WP_000981522.1 | YbaB/EbfC family nucleoid-associated protein | - |
| EQH22_RS05165 (EQH22_05450) | 1022389..1023057 | + | 669 | Protein_1029 | YoaK family protein | - |
| EQH22_RS05170 (EQH22_05455) | 1023276..1023590 | + | 315 | WP_001811359.1 | 50S ribosomal protein L21 | - |
| EQH22_RS05175 (EQH22_05460) | 1023606..1023950 | + | 345 | WP_000613700.1 | ribosomal-processing cysteine protease Prp | - |
| EQH22_RS05180 (EQH22_05465) | 1023967..1024260 | + | 294 | WP_000916509.1 | 50S ribosomal protein L27 | - |
| EQH22_RS05185 (EQH22_05470) | 1024606..1024776 | - | 171 | WP_000123638.1 | hypothetical protein | - |
| EQH22_RS05190 (EQH22_05475) | 1025214..1026131 | + | 918 | WP_000587444.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| EQH22_RS05195 (EQH22_05480) | 1026224..1027072 | - | 849 | WP_000592056.1 | YitT family protein | - |
| EQH22_RS05200 (EQH22_05485) | 1027214..1028053 | + | 840 | WP_000161397.1 | DegV family protein | - |
| EQH22_RS05205 (EQH22_05490) | 1028159..1028434 | + | 276 | WP_001284639.1 | HU family DNA-binding protein | - |
| EQH22_RS05210 (EQH22_05495) | 1028862..1030763 | + | 1902 | WP_000584903.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| EQH22_RS05215 (EQH22_05500) | 1030766..1031629 | + | 864 | WP_000400550.1 | XRE/MutR family transcriptional regulator | - |
| EQH22_RS05220 (EQH22_05505) | 1031709..1032887 | + | 1179 | WP_001083027.1 | MFS transporter | - |
| EQH22_RS05225 (EQH22_05510) | 1032980..1034938 | + | 1959 | WP_001042587.1 | NAD-dependent DNA ligase LigA | - |
| EQH22_RS05230 (EQH22_05515) | 1035050..1037329 | + | 2280 | WP_000283068.1 | type I pullulanase | - |
| EQH22_RS05235 (EQH22_05520) | 1037873..1039297 | + | 1425 | WP_000199371.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| EQH22_RS05240 (EQH22_05530) | 1039780..1041708 | + | 1929 | WP_000370236.1 | 1,4-alpha-glucan branching protein GlgB | - |
| EQH22_RS05245 (EQH22_05535) | 1041698..1042840 | + | 1143 | WP_000787277.1 | glucose-1-phosphate adenylyltransferase | - |
| EQH22_RS05250 (EQH22_05540) | 1042830..1043969 | + | 1140 | WP_000687072.1 | glucose-1-phosphate adenylyltransferase subunit GlgD | - |
| EQH22_RS05255 (EQH22_05545) | 1043966..1045399 | + | 1434 | WP_000697294.1 | glycogen synthase GlgA | - |
| EQH22_RS05260 | 1045518..1045829 | + | 312 | WP_224331470.1 | phosphoserine phosphatase | - |
| EQH22_RS05265 | 1045774..1046103 | + | 330 | WP_001814497.1 | HAD hydrolase family protein | - |
| EQH22_RS05270 (EQH22_05555) | 1046112..1046915 | + | 804 | WP_000706432.1 | glycerate kinase | - |
| EQH22_RS05275 (EQH22_05560) | 1046912..1047358 | - | 447 | WP_000131076.1 | YueI family protein | - |
| EQH22_RS05280 (EQH22_05565) | 1047522..1048826 | + | 1305 | WP_000022815.1 | phosphopyruvate hydratase | - |
| EQH22_RS05285 (EQH22_05570) | 1049160..1050506 | - | 1347 | Protein_1053 | IS1380 family transposase ISSpn5 | Transposase |
| EQH22_RS05290 (EQH22_05575) | 1050672..1051118 | - | 447 | WP_025171968.1 | tyrosine-type recombinase/integrase | - |
| EQH22_RS05295 (EQH22_05580) | 1051018..1051865 | - | 848 | Protein_1055 | IS630 family transposase | - |
| EQH22_RS05300 (EQH22_05590) | 1052036..1052191 | + | 156 | Protein_1056 | diacylglycerol kinase family lipid kinase | - |
| EQH22_RS05305 (EQH22_05595) | 1052391..1055666 | + | 3276 | WP_000772358.1 | ATP-dependent nuclease subunit B | - |
| EQH22_RS05310 (EQH22_05600) | 1055663..1059313 | + | 3651 | WP_000767269.1 | helicase-exonuclease AddAB subunit AddA | - |
| EQH22_RS05315 (EQH22_05605) | 1059528..1060706 | + | 1179 | WP_000174767.1 | hypothetical protein | - |
| EQH22_RS05320 (EQH22_05610) | 1060915..1066698 | + | 5784 | WP_000417142.1 | Immunoglobulin A1 protease | VF |
| EQH22_RS05325 (EQH22_05615) | 1066742..1072117 | + | 5376 | WP_054362867.1 | zinc metalloprotease ZmpD | - |
| EQH22_RS05330 (EQH22_05625) | 1072284..1073630 | + | 1347 | WP_001811769.1 | IS1380 family transposase ISSpn5 | Transposase |
| EQH22_RS05335 (EQH22_05630) | 1073808..1075055 | + | 1248 | WP_000998732.1 | hypothetical protein | - |
| EQH22_RS05340 (EQH22_05635) | 1075087..1075986 | + | 900 | WP_223840796.1 | ABC transporter ATP-binding protein | - |
| EQH22_RS05345 (EQH22_05640) | 1075983..1076783 | + | 801 | WP_000642567.1 | ABC transporter permease | - |
| EQH22_RS05350 (EQH22_05645) | 1076966..1077250 | + | 285 | Protein_1066 | IS200/IS605 family transposase | - |
| EQH22_RS05355 (EQH22_05650) | 1077507..1077730 | + | 224 | Protein_1067 | helix-turn-helix transcriptional regulator | - |
| EQH22_RS05360 (EQH22_05655) | 1078032..1078265 | + | 234 | WP_000404196.1 | hypothetical protein | - |
| EQH22_RS05365 (EQH22_05660) | 1078341..1079807 | + | 1467 | WP_000291914.1 | site-specific integrase | - |
| EQH22_RS05370 (EQH22_05665) | 1079889..1080740 | + | 852 | WP_000201299.1 | ribosome biogenesis GTPase YlqF | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|