MGE detailed information

MGE type: Conjugative plasmid        MGE length: 150853 bp
Accession: NZ_CP028587        Location: 1..150853         Organism: Escherichia coli strain WCHEC4533       Replicon: plasmid pCTXM15_000533


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBR03_RS00665 () 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
DBR03_RS00670 () 1263..2003 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
DBR03_RS00675 () 2124..2312 - 189 WP_001309252.1 hypothetical protein -
DBR03_RS00680 () 2679..3848 + 1170 WP_001072358.1 hypothetical protein -
DBR03_RS00685 () 4074..4249 - 176 Protein_4 IS3 family transposase -
DBR03_RS00690 () 4695..4967 - 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
DBR03_RS00695 () 5492..5928 - 437 Protein_6 IS3 family transposase IS2 Transposase
DBR03_RS00700 () 6210..8180 + 1971 WP_001298664.1 Hemin receptor VF
DBR03_RS00705 () 8187..8978 + 792 WP_000977394.1 DUF4198 domain-containing protein -
DBR03_RS00710 () 9041..9649 - 609 Protein_9 IS66 family transposase ISEc22 Transposase
DBR03_RS00715 () 9717..10496 - 780 WP_001297096.1 IS21 family transposase IS100kyp Transposase
DBR03_RS00720 () 10496..11518 - 1023 WP_000255956.1 IS21 family transposase IS100kyp Transposase
DBR03_RS00725 () 11604..12549 - 946 Protein_12 IS66 family transposase ISEc8 Transposase
DBR03_RS00730 () 12598..12972 - 375 WP_024193849.1 IS66 family transposase ISKpn24 Transposase
DBR03_RS00735 () 12997..13701 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
DBR03_RS00745 () 13754..14143 + 390 Protein_15 Tn3 family transposase TnpR_ISSba14 Transposase
DBR03_RS00750 () 14328..14885 + 558 WP_000108589.1 OsmC family protein -
DBR03_RS00755 () 15027..15608 + 582 WP_000210409.1 HTH-type transcriptional repressor NemR VF
DBR03_RS00760 () 15613..15951 + 339 WP_000888080.1 carboxymuconolactone decarboxylase family protein -
DBR03_RS00765 () 15981..16310 - 330 WP_002431133.1 thioredoxin family protein -
DBR03_RS00770 () 16524..17630 + 1107 WP_000039982.1 alkene reductase -
DBR03_RS00775 () 17696..17959 + 264 Protein_21 DsbA family protein -
DBR03_RS00780 () 18010..18714 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
DBR03_RS00785 () 18903..19600 + 698 Protein_23 IS1 family transposase IS1R Transposase
DBR03_RS00790 () 19597..19860 + 264 WP_049802299.1 antibiotic biosynthesis monooxygenase -
DBR03_RS00795 () 19853..20239 + 387 WP_000460651.1 hypothetical protein -
DBR03_RS00800 () 20247..20933 + 687 WP_001284954.1 winged helix-turn-helix domain-containing protein -
DBR03_RS00805 () 20911..21534 - 624 WP_000088605.1 Tetracycline repressor protein class B from transposon Tn10 VF
DBR03_RS00810 () 21616..22821 + 1206 WP_001089068.1 Tetracycline resistance protein, class B ARG
DBR03_RS00815 () 22856..23553 - 698 Protein_29 IS1 family transposase IS1X2 Transposase
DBR03_RS00830 () 24016..24174 + 159 WP_000449408.1 DsbA family protein -
DBR03_RS00835 () 24164..24670 + 507 WP_000949452.1 protein disulfide oxidoreductase -
DBR03_RS00840 () 24853..25668 + 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
DBR03_RS00850 () 26015..27901 + 1887 WP_000118029.1 FTR1 family iron permease -
DBR03_RS00855 () 27942..28469 + 528 WP_000178050.1 iron transporter -
DBR03_RS00860 () 28573..29952 + 1380 WP_000119836.1 DUF2318 domain-containing protein -
DBR03_RS00865 () 29955..31238 + 1284 WP_000964653.1 ABC transporter permease -
DBR03_RS00870 () 31228..32358 + 1131 WP_000729219.1 ABC transporter permease -
DBR03_RS00875 () 32363..33058 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
DBR03_RS00880 () 33045..33530 + 486 WP_001267176.1 TlpA family protein disulfide reductase -
DBR03_RS00885 () 33555..34040 + 486 WP_000874189.1 hypothetical protein -
DBR03_RS00890 () 34162..34794 + 633 Protein_41 histidine-type phosphatase -
DBR03_RS00895 () 34944..35048 - 105 Protein_42 IS5/IS1182 family transposase -
DBR03_RS00900 () 35326..36330 - 1005 WP_021546935.1 IS110 family transposase IS4321R Transposase
DBR03_RS00905 () 36430..36743 - 314 Protein_44 Tn3 family transposase -
DBR03_RS00910 () 36770..37522 - 753 WP_000734115.1 alpha/beta hydrolase -
DBR03_RS00915 () 37764..38636 + 873 WP_000090196.1 DMT family transporter -
DBR03_RS00920 () 38767..39990 + 1224 WP_000872613.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
DBR03_RS00925 () 40176..40949 - 774 WP_032152933.1 SDR family oxidoreductase -
DBR03_RS00930 () 41015..41461 - 447 Protein_49 DsbA family protein -
DBR03_RS00935 () 41526..42230 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
DBR03_RS00945 () 42282..42518 + 237 Protein_51 IS6 family transposase -
DBR03_RS00960 () 43011..43595 - 585 WP_001137892.1 TetR family transcriptional regulator -
DBR03_RS00965 () 43595..44833 - 1239 WP_000004159.1 MFS transporter -
DBR03_RS00970 () 44830..45735 - 906 WP_000219391.1 hypothetical protein ARG
DBR03_RS00980 () 45857..46561 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
DBR03_RS00990 () 46902..47105 - 204 WP_064765192.1 hypothetical protein -
DBR03_RS01000 () 47302..48141 - 840 WP_000259031.1 Dihydropteroate synthase ARG
DBR03_RS01005 () 48135..48482 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
DBR03_RS01010 () 48688..49476 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
DBR03_RS01015 () 49607..50080 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
DBR03_RS01020 () 50238..51251 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
DBR03_RS26915 () 51454..51744 + 291 WP_032152941.1 DUF3330 domain-containing protein -
DBR03_RS01030 () 51781..52485 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
DBR03_RS01035 () 52539..53507 + 969 Protein_64 IS1380 family transposase ISEcp1 Transposase
DBR03_RS01040 () 53763..54638 + 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
DBR03_RS01045 () 54685..55017 - 333 WP_001393253.1 WbuC family cupin fold metalloprotein -
DBR03_RS01050 () 55031..57274 + 2244 Protein_67 Tn3 family transposase TnpA_Tn3 Transposase
DBR03_RS01055 () 57339..58043 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
DBR03_RS01060 () 58097..59145 - 1049 Protein_69 IS3 family transposase ISKpn11 Transposase
DBR03_RS01065 () 59237..59779 - 543 WP_002063889.1 AAA family ATPase -
DBR03_RS01070 () 59792..60652 - 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
DBR03_RS01075 () 60759..61463 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
DBR03_RS01080 () 61517..61957 - 441 Protein_73 CatB-related O-acetyltransferase -
DBR03_RS01085 () 62095..62925 - 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
DBR03_RS01090 () 63056..63610 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
DBR03_RS01095 () 63754..64458 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
DBR03_RS01100 () 64524..65036 + 513 Protein_77 Tn3 family transposase TnpA_TnAs1 Transposase
DBR03_RS01105 () 65060..65665 - 606 WP_000509966.1 Tn3 family transposase TnpR_Tn5403 Transposase
DBR03_RS01110 () 65760..68657 + 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
DBR03_RS01115 () 68794..69195 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
DBR03_RS01120 () 69128..69385 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
DBR03_RS01125 () 69478..70131 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
DBR03_RS01135 () 71070..71927 - 858 WP_032152935.1 incFII family plasmid replication initiator RepA -
DBR03_RS01140 () 71920..71994 - 75 WP_001365705.1 RepA leader peptide Tap -
DBR03_RS01150 () 72229..72486 - 258 WP_000083821.1 replication regulatory protein RepA -
DBR03_RS01160 () 72891..73913 + 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
DBR03_RS01165 () 74385..74738 + 354 WP_000005489.1 hypothetical protein -
DBR03_RS01170 () 75151..75729 - 579 WP_032152936.1 DUF2726 domain-containing protein -
DBR03_RS01175 () 75762..76459 + 698 Protein_89 IS1 family transposase IS1A Transposase
DBR03_RS01180 () 76568..76930 + 363 WP_059330006.1 IS66 family transposase ISEc23 Transposase
DBR03_RS01185 () 76927..77277 + 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
DBR03_RS01190 () 77308..77529 + 222 WP_000080227.1 hypothetical protein -
DBR03_RS01195 () 77481..77822 + 342 Protein_93 transposase -
DBR03_RS01200 () 77886..78365 - 480 WP_001496175.1 ArgR family transcriptional regulator -
DBR03_RS01205 () 78446..79849 - 1404 WP_000514417.1 YfcC family protein -
DBR03_RS01210 () 79897..80901 - 1005 WP_000154545.1 Ornithine carbamoyltransferase VF
DBR03_RS01215 () 80986..81897 - 912 WP_000440183.1 carbamate kinase -
DBR03_RS01220 () 81908..83128 - 1221 WP_000410951.1 arginine deiminase -
DBR03_RS01225 () 84021..84503 + 483 Protein_99 VENN motif pre-toxin domain-containing protein -
DBR03_RS01230 () 84449..84895 - 447 Protein_100 incFII family plasmid replication initiator RepA -
DBR03_RS01235 () 84888..84962 - 75 WP_032336874.1 RepA leader peptide Tap -
DBR03_RS01245 () 85198..85455 - 258 WP_000083833.1 replication regulatory protein RepA -
DBR03_RS01250 () 85739..85945 - 207 WP_015387399.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 85932..85993 + 62 NuclAT_2 - Antitoxin Detail
- () 85932..85993 + 62 NuclAT_2 - Antitoxin Detail
- () 85932..85993 + 62 NuclAT_2 - Antitoxin Detail
- () 85932..85993 + 62 NuclAT_2 - Antitoxin Detail
DBR03_RS01260 () 86132..86314 - 183 WP_000968309.1 hypothetical protein -
DBR03_RS01265 () 86415..87031 + 617 Protein_105 IS1 family transposase IS1G Transposase
DBR03_RS01270 () 87069..88640 - 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
DBR03_RS01275 () 88660..89007 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
DBR03_RS01280 () 89007..89684 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
DBR03_RS26920 () 89739..89828 + 90 Protein_109 IS1 family transposase -
DBR03_RS01295 () 90129..90341 - 213 WP_005012601.1 hypothetical protein -
DBR03_RS01300 () 90475..91035 - 561 WP_000139363.1 fertility inhibition protein FinO -
DBR03_RS01305 () 91090..91836 - 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
DBR03_RS01310 () 91856..96976 - 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
DBR03_RS01315 () 96976..99174 - 2199 WP_046464200.1 type IV conjugative transfer system coupling protein TraD -
DBR03_RS01325 () 99426..100157 - 732 WP_000850424.1 complement resistance protein TraT -
DBR03_RS01330 () 100171..100680 - 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
DBR03_RS01335 () 100677..103502 - 2826 WP_087503535.1 conjugal transfer mating pair stabilization protein TraG -
DBR03_RS01340 () 103499..104872 - 1374 WP_021518370.1 conjugal transfer protein TraH -
DBR03_RS01345 () 104859..105251 - 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
DBR03_RS01350 () 105205..105579 - 375 WP_071788165.1 P-type conjugative transfer protein TrbJ -
DBR03_RS01355 () 105509..106063 - 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
DBR03_RS01360 () 106050..106334 - 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
DBR03_RS01365 () 106415..106750 + 336 WP_000415571.1 hypothetical protein -
DBR03_RS01370 () 106731..107072 - 342 WP_000556794.1 conjugal transfer protein TrbA -
DBR03_RS01375 () 107086..107829 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
DBR03_RS01380 () 107822..108079 - 258 WP_000864312.1 conjugal transfer protein TrbE -
DBR03_RS01385 () 108106..109914 - 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
DBR03_RS01390 () 109911..110549 - 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
DBR03_RS01395 () 110558..111550 - 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
DBR03_RS01400 () 111547..112179 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
DBR03_RS01405 () 112176..112562 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
DBR03_RS01410 () 112559..115186 - 2628 WP_001064245.1 type IV secretion system protein TraC -
DBR03_RS01415 () 115346..115567 - 222 WP_001278689.1 conjugal transfer protein TraR -
DBR03_RS01420 () 115702..116217 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
DBR03_RS01425 () 116214..116465 - 252 WP_001038342.1 conjugal transfer protein TrbG -
DBR03_RS01430 () 116477..116707 - 231 WP_001352845.1 conjugal transfer protein TrbD -
DBR03_RS01435 () 116661..117251 - 591 WP_000002787.1 conjugal transfer protein TraP -
DBR03_RS01440 () 117241..118668 - 1428 WP_000146685.1 conjugal transfer protein TraB -
DBR03_RS01445 () 118668..119372 - 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
DBR03_RS01450 () 119383..119949 - 567 WP_021514868.1 type IV conjugative transfer system protein TraE -
DBR03_RS01455 () 119971..120282 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
DBR03_RS01460 () 120297..120662 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
DBR03_RS01465 () 120695..121090 - 396 WP_001309237.1 conjugal transfer relaxosome protein TraY -
DBR03_RS01470 () 121189..121878 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
DBR03_RS01475 () 122065..122448 - 384 WP_001151524.1 relaxosome protein TraM -
DBR03_RS01480 () 122769..123371 + 603 WP_013362798.1 hypothetical protein VF
DBR03_RS01485 () 123668..124489 - 822 WP_001234426.1 DUF945 domain-containing protein -
DBR03_RS01490 () 124607..124894 - 288 WP_000107535.1 hypothetical protein -
DBR03_RS01500 () 126096..127763 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
DBR03_RS01505 () 128158..128316 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 128360..128391 - 32 NuclAT_1 - Antitoxin Detail
- () 128360..128391 - 32 NuclAT_1 - Antitoxin Detail
- () 128360..128391 - 32 NuclAT_1 - Antitoxin Detail
- () 128360..128391 - 32 NuclAT_1 - Antitoxin Detail
- () 129833..130030 - 198 NuclAT_0 - -
- () 129833..130030 - 198 NuclAT_0 - -
- () 129833..130030 - 198 NuclAT_0 - -
- () 129833..130030 - 198 NuclAT_0 - -
DBR03_RS26925 () 129842..130030 + 189 WP_001299721.1 hypothetical protein -
DBR03_RS01515 () 130042..130761 - 720 WP_001276238.1 plasmid SOS inhibition protein A -
DBR03_RS01520 () 130758..131192 - 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
DBR03_RS01525 () 131247..131444 - 198 Protein_155 hypothetical protein -
DBR03_RS01530 () 131472..131705 - 234 WP_000005990.1 DUF905 family protein -
DBR03_RS01535 () 131773..132312 - 540 WP_000290840.1 single-stranded DNA-binding protein -
DBR03_RS01545 () 133515..135182 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
DBR03_RS01555 () 135495..135686 - 192 WP_001027495.1 hypothetical protein -
DBR03_RS01560 () 135683..136105 - 423 WP_000271685.1 DUF1380 family protein -
DBR03_RS01565 () 136152..136454 - 303 WP_001666994.1 antirestriction protein -
DBR03_RS01575 () 136991..137761 - 771 WP_001006251.1 hypothetical protein -
DBR03_RS01580 () 137806..138240 - 435 WP_001546462.1 DUF1380 family protein -
DBR03_RS01585 () 138254..138475 - 222 WP_001104873.1 hypothetical protein -
DBR03_RS01590 () 138476..139159 - 684 WP_032181561.1 DNA methylase -
DBR03_RS01595 () 139236..139540 - 305 Protein_166 hypothetical protein -
DBR03_RS01600 () 139544..140446 - 903 WP_064766247.1 DUF1281 domain-containing protein -
DBR03_RS01610 () 141184..142155 - 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
DBR03_RS01615 () 142155..143321 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
DBR03_RS01620 () 143909..144664 - 756 WP_000852146.1 replication initiation protein RepE -
DBR03_RS01625 () 145386..146192 - 807 WP_000016970.1 site-specific integrase -
DBR03_RS01630 () 146193..146498 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB -
DBR03_RS01635 () 146500..146718 - 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA -
DBR03_RS01650 () 149038..149679 + 642 WP_000990667.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance