MGE detailed information
MGE type: Conjugative plasmid MGE length: 161986 bp
Accession: NZ_CP025148 Location: 1..161986 Organism: Klebsiella pneumoniae strain KP1766 Replicon: plasmid KP1766_p2
Accession: NZ_CP025148 Location: 1..161986 Organism: Klebsiella pneumoniae strain KP1766 Replicon: plasmid KP1766_p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CXB26_RS28415 () | 2..112 | + | 111 | Protein_0 | IS1 family transposase | - |
| CXB26_RS28420 () | 122..745 | + | 624 | WP_101134916.1 | Transcriptional regulatory protein CusR | VF |
| CXB26_RS28425 () | 738..2213 | + | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| CXB26_RS28430 () | 2464..2895 | + | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| CXB26_RS28435 () | 3191..3733 | - | 543 | Protein_4 | ISL3 family transposase ISKpn25 | Transposase |
| CXB26_RS28440 () | 3749..4233 | - | 485 | Protein_5 | IS1 family transposase IS1X2 | Transposase |
| CXB26_RS28445 () | 4324..5531 | + | 1208 | WP_085955172.1 | IS3 family transposase ISEcl1 | Transposase |
| CXB26_RS28455 () | 5722..6419 | + | 698 | Protein_7 | IS1 family transposase IS1X2 | Transposase |
| CXB26_RS28460 () | 6571..8568 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| CXB26_RS28465 () | 8631..9908 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| CXB26_RS28470 () | 10891..12345 | - | 1455 | Protein_10 | putative cyclic di-GMP phosphodiesterase PdeC | VF |
| CXB26_RS28475 () | 12948..13205 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| CXB26_RS28480 () | 13878..14846 | - | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| CXB26_RS28485 () | 14866..15177 | + | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| CXB26_RS28490 () | 15204..16151 | - | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| CXB26_RS28495 () | 17295..18035 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| CXB26_RS28505 () | 18752..19762 | - | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| CXB26_RS28510 () | 20514..21680 | + | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
| CXB26_RS28515 () | 21680..22651 | + | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CXB26_RS28530 () | 24088..25286 | + | 1199 | Protein_19 | IS200-IS605 family transposase IS609 | Transposase |
| CXB26_RS28535 () | 25309..25524 | - | 216 | Protein_20 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| CXB26_RS28540 () | 25603..26874 | - | 1272 | WP_004152715.1 | Y-family DNA polymerase | - |
| CXB26_RS28545 () | 26874..27299 | - | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CXB26_RS28555 () | 27702..29189 | + | 1488 | Protein_23 | group II intron reverse transcriptase/maturase | - |
| CXB26_RS28560 () | 29423..29653 | + | 231 | WP_004152753.1 | hypothetical protein | - |
| CXB26_RS28570 () | 30174..30599 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| CXB26_RS28575 () | 30836..31090 | + | 255 | WP_023157779.1 | DNA polymerase III subunit theta | - |
| CXB26_RS28580 () | 31125..31442 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| CXB26_RS28590 () | 32224..32451 | + | 228 | WP_004178072.1 | hypothetical protein | - |
| CXB26_RS28595 () | 32543..32773 | + | 231 | WP_004198570.1 | hypothetical protein | - |
| CXB26_RS28600 () | 32825..34180 | + | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| CXB26_RS28605 () | 34228..34791 | + | 564 | WP_004152645.1 | methyltransferase | - |
| CXB26_RS28620 () | 35567..36109 | + | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| CXB26_RS28625 () | 36158..36406 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| CXB26_RS28630 () | 36476..38533 | + | 2058 | WP_023287107.1 | ParB/RepB/Spo0J family partition protein | - |
| CXB26_RS28635 () | 38578..39009 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| CXB26_RS28640 () | 39006..39734 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| CXB26_RS28645 () | 39731..40057 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| CXB26_RS28650 () | 40113..40487 | + | 375 | WP_023287106.1 | hypothetical protein | - |
| - () | 40547..40671 | + | 125 | NuclAT_0 | - | - |
| - () | 40547..40671 | + | 125 | NuclAT_0 | - | - |
| - () | 40547..40671 | + | 125 | NuclAT_0 | - | - |
| - () | 40547..40671 | + | 125 | NuclAT_0 | - | - |
| CXB26_RS28660 () | 40715..40873 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| CXB26_RS28665 () | 41567..41839 | + | 273 | WP_023287105.1 | hypothetical protein | - |
| CXB26_RS28670 () | 41836..42186 | + | 351 | WP_023287104.1 | hypothetical protein | - |
| CXB26_RS28685 () | 42818..43174 | + | 357 | WP_004152717.1 | hypothetical protein | - |
| CXB26_RS28690 () | 43235..43447 | + | 213 | WP_004152718.1 | hypothetical protein | - |
| CXB26_RS28695 () | 43458..43682 | + | 225 | WP_004152719.1 | hypothetical protein | - |
| CXB26_RS28700 () | 43763..44083 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CXB26_RS28705 () | 44073..44351 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| CXB26_RS28710 () | 44352..44765 | + | 414 | WP_023287139.1 | helix-turn-helix domain-containing protein | - |
| CXB26_RS28730 () | 45597..46418 | + | 822 | WP_023287138.1 | DUF945 domain-containing protein | - |
| CXB26_RS28735 () | 46451..46780 | + | 330 | WP_011977736.1 | hypothetical protein | - |
| CXB26_RS28740 () | 46813..47298 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| CXB26_RS28745 () | 47689..48105 | + | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| CXB26_RS28750 () | 48305..49042 | + | 738 | WP_013214018.1 | conjugal transfer protein TrbJ | - |
| CXB26_RS28755 () | 49157..49363 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| CXB26_RS28760 () | 49425..49793 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| CXB26_RS28765 () | 49807..50112 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| CXB26_RS28770 () | 50132..50698 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| CXB26_RS28775 () | 50685..51425 | + | 741 | WP_013214019.1 | type-F conjugative transfer system secretin TraK | - |
| CXB26_RS28780 () | 51425..52849 | + | 1425 | WP_023287137.1 | conjugal transfer protein TraB | - |
| CXB26_RS28785 () | 52922..53506 | + | 585 | WP_023287136.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CXB26_RS28790 () | 53829..54047 | + | 219 | WP_004195468.1 | hypothetical protein | - |
| CXB26_RS28795 () | 54048..54359 | + | 312 | WP_023287135.1 | hypothetical protein | - |
| CXB26_RS28800 () | 54426..54830 | + | 405 | WP_004197817.1 | hypothetical protein | - |
| CXB26_RS28815 () | 55207..55605 | + | 399 | WP_014343490.1 | hypothetical protein | - |
| CXB26_RS28820 () | 55677..58316 | + | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| CXB26_RS28825 () | 58316..58705 | + | 390 | WP_013214025.1 | type-F conjugative transfer system protein TrbI | - |
| CXB26_RS28830 () | 58705..59340 | + | 636 | WP_013214026.1 | type-F conjugative transfer system protein TraW | - |
| CXB26_RS28835 () | 59375..59776 | + | 402 | WP_004194979.1 | hypothetical protein | - |
| CXB26_RS28840 () | 59773..60762 | + | 990 | WP_013214027.1 | conjugal transfer pilus assembly protein TraU | - |
| CXB26_RS28845 () | 60775..61413 | + | 639 | WP_004193871.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CXB26_RS28850 () | 61472..63427 | + | 1956 | WP_023287134.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CXB26_RS28855 () | 63459..63713 | + | 255 | WP_023287133.1 | conjugal transfer protein TrbE | - |
| CXB26_RS28860 () | 63691..63939 | + | 249 | WP_013214029.1 | hypothetical protein | - |
| CXB26_RS28865 () | 63952..64278 | + | 327 | WP_004152676.1 | hypothetical protein | - |
| CXB26_RS28870 () | 64299..65051 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CXB26_RS28875 () | 65062..65301 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CXB26_RS28880 () | 65273..65830 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CXB26_RS28885 () | 65876..66319 | + | 444 | WP_023287131.1 | F-type conjugal transfer protein TrbF | - |
| CXB26_RS28890 () | 66297..67676 | + | 1380 | WP_072159474.1 | conjugal transfer protein TraH | - |
| CXB26_RS28895 () | 67676..70525 | + | 2850 | WP_023287129.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CXB26_RS28900 () | 70531..71058 | + | 528 | WP_032409657.1 | conjugal transfer protein TraS | - |
| CXB26_RS28905 () | 71247..71393 | + | 147 | WP_004197893.1 | hypothetical protein | - |
| CXB26_RS28910 () | 71359..71568 | + | 210 | Protein_82 | complement resistance protein TraT | - |
| CXB26_RS28915 () | 71625..72593 | - | 969 | WP_101169236.1 | IS5 family transposase IS903B | Transposase |
| CXB26_RS28920 () | 72671..73042 | + | 372 | WP_023287125.1 | TraT complement resistance protein | - |
| CXB26_RS30140 () | 73235..73924 | + | 690 | WP_013023831.1 | hypothetical protein | - |
| CXB26_RS28930 () | 74051..76360 | + | 2310 | Protein_86 | type IV conjugative transfer system coupling protein TraD | - |
| CXB26_RS28935 () | 76360..81618 | + | 5259 | WP_023287123.1 | Multifunctional conjugation protein TraI | Relaxase |
| CXB26_RS28940 () | 81708..82433 | + | 726 | WP_009309882.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| CXB26_RS28945 () | 82588..83184 | + | 597 | WP_009309883.1 | fertility inhibition protein FinO | - |
| CXB26_RS28950 () | 83204..83551 | + | 348 | WP_009309884.1 | hypothetical protein | - |
| CXB26_RS28955 () | 84022..84666 | + | 645 | WP_009309885.1 | hypothetical protein | - |
| CXB26_RS28960 () | 84722..85372 | + | 651 | WP_009309886.1 | DUF2726 domain-containing protein | - |
| CXB26_RS28965 () | 85369..85680 | + | 312 | WP_009309887.1 | hypothetical protein | - |
| CXB26_RS28975 () | 86177..86509 | + | 333 | WP_001549890.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CXB26_RS28980 () | 86515..87228 | + | 714 | WP_025801347.1 | arsenical resistance protein ArsH | - |
| CXB26_RS28985 () | 87286..87714 | - | 429 | WP_001549888.1 | glutaredoxin-dependent arsenate reductase | - |
| CXB26_RS28990 () | 87764..89047 | - | 1284 | WP_001549887.1 | arsenic transporter | - |
| CXB26_RS28995 () | 89143..89496 | - | 354 | WP_001549886.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CXB26_RS29000 () | 89980..91458 | + | 1479 | WP_001549885.1 | SulP family inorganic anion transporter | - |
| CXB26_RS29005 () | 91477..92304 | + | 828 | WP_004118529.1 | universal stress protein | - |
| CXB26_RS29010 () | 92376..93572 | - | 1197 | WP_001549953.1 | MFS transporter | - |
| CXB26_RS29015 () | 94101..94475 | + | 375 | WP_004118534.1 | fluoride efflux transporter CrcB | - |
| CXB26_RS29020 () | 94750..95898 | + | 1149 | WP_011977829.1 | Na+/H+ antiporter NhaA | - |
| CXB26_RS29025 () | 96252..96584 | - | 333 | WP_004118538.1 | multidrug efflux SMR transporter | - |
| CXB26_RS29030 () | 96847..97551 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CXB26_RS29035 () | 97616..97803 | + | 188 | Protein_106 | IS3 family transposase | - |
| CXB26_RS29040 () | 97857..98561 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CXB26_RS29045 () | 98767..99075 | - | 309 | Protein_108 | IS5 family transposase ISThi1 | Transposase |
| CXB26_RS29050 () | 99400..101115 | - | 1716 | WP_101169254.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| CXB26_RS29055 () | 101225..104254 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| CXB26_RS29060 () | 104361..105386 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| CXB26_RS29065 () | 105383..106162 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| CXB26_RS29070 () | 106294..107175 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| CXB26_RS29075 () | 107425..108744 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| CXB26_RS29080 () | 109173..110000 | + | 828 | WP_004153729.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| CXB26_RS29085 () | 109997..110860 | + | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| CXB26_RS29090 () | 110869..111696 | + | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| CXB26_RS29095 () | 111705..112715 | + | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| CXB26_RS29100 () | 112709..113578 | + | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| CXB26_RS29105 () | 113686..114205 | + | 520 | Protein_120 | IS5 family transposase ISPst7 | Transposase |
| CXB26_RS29120 () | 114787..115767 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| CXB26_RS29125 () | 116026..116723 | - | 698 | Protein_122 | IS1 family transposase IS1X2 | Transposase |
| CXB26_RS29130 () | 116908..117024 | - | 117 | Protein_123 | transposase domain-containing protein | - |
| CXB26_RS29610 () | 116969..117232 | - | 264 | WP_004118209.1 | IS66 family transposase ISPpu19 | Transposase |
| CXB26_RS29615 () | 117247..117510 | + | 264 | WP_004118208.1 | hypothetical protein | - |
| CXB26_RS29140 () | 117754..118035 | + | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| CXB26_RS29145 () | 118070..118639 | + | 570 | WP_004152117.1 | Spore protein SP21 | VF |
| CXB26_RS29150 () | 118754..121549 | + | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| CXB26_RS29155 () | 121549..121746 | + | 198 | WP_004152115.1 | hypothetical protein | - |
| CXB26_RS29165 () | 121984..122733 | + | 750 | WP_009483782.1 | phosphate-starvation-inducible PsiE family protein | - |
| CXB26_RS29170 () | 122720..123682 | + | 963 | WP_004152113.1 | M48 family metalloprotease | - |
| CXB26_RS29175 () | 123770..125024 | + | 1255 | Protein_132 | IS3 family transposase ISKpn38 | Transposase |
| CXB26_RS29180 () | 125525..126871 | - | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| CXB26_RS29185 () | 127083..127565 | - | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| CXB26_RS29190 () | 127553..127819 | - | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| CXB26_RS29195 () | 127995..128249 | - | 255 | WP_004152108.1 | hypothetical protein | - |
| CXB26_RS29200 () | 128325..128582 | - | 258 | WP_004152107.1 | hypothetical protein | - |
| CXB26_RS29205 () | 128631..128834 | - | 204 | WP_004152106.1 | hemolysin expression modulator Hha | - |
| CXB26_RS29210 () | 128868..129236 | - | 369 | WP_004152105.1 | hypothetical protein | - |
| CXB26_RS29215 () | 129280..129774 | - | 495 | WP_004152104.1 | DNA-binding protein | - |
| CXB26_RS29220 () | 129805..130380 | - | 576 | WP_004152103.1 | hypothetical protein | - |
| CXB26_RS29225 () | 130368..130637 | - | 270 | WP_004152102.1 | hypothetical protein | - |
| CXB26_RS29230 () | 130995..131345 | + | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| CXB26_RS29235 () | 131395..131757 | + | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| CXB26_RS29240 () | 131775..133526 | + | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| CXB26_RS29245 () | 133574..134863 | + | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| CXB26_RS29250 () | 134876..135301 | + | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| CXB26_RS29255 () | 135334..135870 | - | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| CXB26_RS29260 () | 135992..137742 | - | 1751 | Protein_149 | arsenical pump-driving ATPase | - |
| CXB26_RS29265 () | 137767..138129 | - | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| CXB26_RS29270 () | 138205..138750 | - | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| CXB26_RS29275 () | 138759..139472 | - | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| CXB26_RS29280 () | 139469..139795 | - | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CXB26_RS29285 () | 140127..140624 | + | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| CXB26_RS29290 () | 140674..141183 | - | 510 | WP_031944101.1 | aquaporin | - |
| CXB26_RS29295 () | 141245..142865 | + | 1621 | Protein_156 | ISL3 family transposase | - |
| CXB26_RS29300 () | 142926..143105 | + | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CXB26_RS29305 () | 143337..143771 | - | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| CXB26_RS29310 () | 143988..145388 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| CXB26_RS29315 () | 145385..146065 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| CXB26_RS29320 () | 146120..147049 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| CXB26_RS29325 () | 147054..147434 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| CXB26_RS29330 () | 147474..148364 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| CXB26_RS29335 () | 148370..150187 | - | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| CXB26_RS29340 () | 150421..150870 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| CXB26_RS29345 () | 151159..151896 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| CXB26_RS29350 () | 151930..152127 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| CXB26_RS29355 () | 152168..154615 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| CXB26_RS29360 () | 154742..155182 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| CXB26_RS29365 () | 155269..158415 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| CXB26_RS29370 () | 158426..159718 | - | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| CXB26_RS29375 () | 159832..160185 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| CXB26_RS29380 () | 160214..161599 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| CXB26_RS29385 () | 161789..161869 | + | 81 | Protein_174 | DNA-binding response regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|