MGE detailed information
MGE type: Conjugative plasmid MGE length: 147945 bp
Accession: NZ_CP024193 Location: 1..147945 Organism: Klebsiella pneumoniae isolate KSB1_5D Replicon: plasmid unnamed2
Accession: NZ_CP024193 Location: 1..147945 Organism: Klebsiella pneumoniae isolate KSB1_5D Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CS526_RS28135 () | 1..1011 | + | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| CS526_RS28145 () | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| CS526_RS28150 () | 3612..4559 | + | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| CS526_RS28155 () | 4586..4897 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| CS526_RS28165 () | 4917..5885 | + | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| CS526_RS28170 () | 6558..6815 | - | 258 | WP_004197688.1 | hypothetical protein | - |
| CS526_RS28175 () | 7417..8871 | + | 1455 | WP_020444838.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| CS526_RS28180 () | 9854..11131 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| CS526_RS28185 () | 11194..13191 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| CS526_RS28190 () | 13343..14040 | - | 698 | Protein_9 | IS1 family transposase IS1X2 | Transposase |
| CS526_RS28205 () | 15529..16013 | + | 485 | Protein_11 | IS1 family transposase IS1X2 | Transposase |
| CS526_RS28210 () | 16029..16571 | + | 543 | Protein_12 | ISL3 family transposase ISKpn25 | Transposase |
| CS526_RS28215 () | 16867..17298 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| CS526_RS28220 () | 17549..19024 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| CS526_RS28225 () | 19017..19697 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| CS526_RS28230 () | 19887..21272 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| CS526_RS28235 () | 21301..21654 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| CS526_RS28240 () | 21768..23060 | + | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| CS526_RS28245 () | 23071..26217 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| CS526_RS28250 () | 26304..26744 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| CS526_RS28255 () | 26871..29318 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| CS526_RS28260 () | 29359..29556 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| CS526_RS28265 () | 29590..30327 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| CS526_RS28270 () | 30616..31065 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| CS526_RS28275 () | 31299..33116 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| CS526_RS28280 () | 33122..34012 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| CS526_RS28285 () | 34052..34432 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| CS526_RS28290 () | 34437..35366 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| CS526_RS28295 () | 35421..36101 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| CS526_RS28300 () | 36098..37498 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| CS526_RS28305 () | 37715..38149 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| CS526_RS28310 () | 38381..38560 | - | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CS526_RS28315 () | 38621..40241 | - | 1621 | Protein_33 | ISL3 family transposase | - |
| CS526_RS28320 () | 40303..40812 | + | 510 | WP_031944101.1 | aquaporin | - |
| CS526_RS28325 () | 40862..41359 | - | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| CS526_RS28330 () | 41691..42017 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CS526_RS28335 () | 42014..42727 | + | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| CS526_RS28340 () | 42736..43281 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| CS526_RS28345 () | 43357..43719 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| CS526_RS28350 () | 43744..45494 | + | 1751 | Protein_40 | arsenical pump-driving ATPase | - |
| CS526_RS28355 () | 45616..46152 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| CS526_RS28360 () | 46185..46610 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| CS526_RS28365 () | 46623..47912 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| CS526_RS28370 () | 47960..49711 | - | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| CS526_RS28375 () | 49729..50091 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| CS526_RS28380 () | 50141..50491 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| CS526_RS28385 () | 50849..51118 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| CS526_RS28390 () | 51106..51681 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| CS526_RS28395 () | 51712..52206 | + | 495 | WP_004152104.1 | DNA-binding protein | - |
| CS526_RS28400 () | 52250..52618 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| CS526_RS28405 () | 52652..52855 | + | 204 | WP_004152106.1 | hemolysin expression modulator Hha | - |
| CS526_RS28410 () | 52904..53161 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| CS526_RS28415 () | 53237..53491 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| CS526_RS28420 () | 53667..53933 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| CS526_RS28425 () | 53921..54403 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| CS526_RS28430 () | 54615..55961 | + | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| CS526_RS28435 () | 56462..57716 | - | 1255 | Protein_57 | IS3 family transposase ISKpn38 | Transposase |
| CS526_RS28440 () | 57804..58766 | - | 963 | WP_004152113.1 | M48 family metalloprotease | - |
| CS526_RS28445 () | 58753..59502 | - | 750 | WP_009483782.1 | phosphate-starvation-inducible PsiE family protein | - |
| CS526_RS28455 () | 59740..59937 | - | 198 | WP_004152115.1 | hypothetical protein | - |
| CS526_RS28460 () | 59937..62732 | - | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| CS526_RS28465 () | 62847..63416 | - | 570 | WP_004152117.1 | Spore protein SP21 | VF |
| CS526_RS28470 () | 63451..63732 | - | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| CS526_RS29970 () | 63976..64239 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| CS526_RS29975 () | 64254..64517 | + | 264 | WP_004118209.1 | IS66 family transposase ISPpu19 | Transposase |
| CS526_RS28480 () | 64462..64578 | + | 117 | Protein_66 | transposase domain-containing protein | - |
| CS526_RS28485 () | 64763..65460 | + | 698 | Protein_67 | IS1 family transposase IS1X2 | Transposase |
| CS526_RS28490 () | 65719..66699 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| CS526_RS28505 () | 67281..67800 | - | 520 | Protein_69 | IS5 family transposase ISPst7 | Transposase |
| CS526_RS28510 () | 67908..68777 | - | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| CS526_RS28515 () | 68771..69781 | - | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| CS526_RS28520 () | 69790..70617 | - | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| CS526_RS28525 () | 70626..71489 | - | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| CS526_RS28530 () | 71486..72313 | - | 828 | WP_004153729.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| CS526_RS28535 () | 72655..72963 | + | 309 | Protein_75 | IS5 family transposase ISThi1 | Transposase |
| CS526_RS28540 () | 73169..73873 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CS526_RS30615 () | 74014..74169 | + | 156 | WP_000075580.1 | hypothetical protein | - |
| CS526_RS28545 () | 74218..74622 | + | 405 | WP_198406606.1 | hypothetical protein | - |
| CS526_RS28550 () | 74552..75199 | + | 648 | WP_125551040.1 | hypothetical protein | - |
| CS526_RS30620 () | 75226..75387 | + | 162 | WP_011977825.1 | hypothetical protein | - |
| CS526_RS28560 () | 75384..75995 | - | 612 | WP_016338366.1 | DUF2913 family protein | - |
| CS526_RS28565 () | 76049..76330 | - | 282 | WP_001568067.1 | hypothetical protein | - |
| CS526_RS28570 () | 76503..76838 | + | 336 | WP_011977766.1 | C2H2-type zinc finger protein | - |
| CS526_RS28585 () | 77879..78736 | - | 858 | WP_004152292.1 | incFII family plasmid replication initiator RepA | - |
| CS526_RS28590 () | 78729..78806 | - | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| CS526_RS28595 () | 79023..79301 | - | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| CS526_RS28600 () | 79622..80101 | - | 480 | WP_009485932.1 | Phospholipase D | VF |
| CS526_RS28605 () | 80442..80720 | - | 279 | WP_004152296.1 | bacteriocin immunity protein | - |
| CS526_RS28610 () | 80722..83043 | - | 2322 | WP_004178051.1 | klebicin B-related nuclease bacteriocin | - |
| CS526_RS28620 () | 83400..83945 | + | 546 | WP_004178052.1 | hypothetical protein | - |
| CS526_RS28625 () | 84173..84520 | - | 348 | WP_004152301.1 | hypothetical protein | - |
| CS526_RS28630 () | 84540..85136 | - | 597 | WP_004178053.1 | fertility inhibition protein FinO | - |
| CS526_RS28635 () | 85294..86019 | - | 726 | WP_004152303.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| CS526_RS28640 () | 86099..91360 | - | 5262 | WP_004153029.1 | Multifunctional conjugation protein TraI | Relaxase |
| CS526_RS28645 () | 91360..93669 | - | 2310 | Protein_95 | type IV conjugative transfer system coupling protein TraD | - |
| CS526_RS28650 () | 94029..94760 | - | 732 | WP_004152629.1 | complement resistance protein TraT | - |
| CS526_RS28655 () | 94950..95477 | - | 528 | WP_004153030.1 | hypothetical protein | - |
| CS526_RS28660 () | 95483..98332 | - | 2850 | WP_004178054.1 | conjugal transfer mating pair stabilization protein TraG | - |
| CS526_RS28665 () | 98332..99702 | - | 1371 | WP_004178055.1 | conjugal transfer protein TraH | - |
| CS526_RS28670 () | 99689..100117 | - | 429 | WP_004152689.1 | hypothetical protein | - |
| CS526_RS28675 () | 100110..100682 | - | 573 | WP_004152688.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| CS526_RS28680 () | 100654..100893 | - | 240 | WP_004152687.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| CS526_RS28685 () | 100904..101656 | - | 753 | WP_004152686.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| CS526_RS28690 () | 101677..102003 | - | 327 | WP_004152685.1 | hypothetical protein | - |
| CS526_RS28700 () | 102231..102467 | - | 237 | WP_004152683.1 | conjugal transfer protein TrbE | - |
| CS526_RS28705 () | 102499..104454 | - | 1956 | WP_004153093.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| CS526_RS28710 () | 104502..105140 | - | 639 | WP_004152682.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| CS526_RS28715 () | 105153..106145 | - | 993 | WP_004178057.1 | conjugal transfer pilus assembly protein TraU | - |
| CS526_RS28720 () | 106156..106782 | - | 627 | WP_004152590.1 | type-F conjugative transfer system protein TraW | - |
| CS526_RS28725 () | 106782..107171 | - | 390 | WP_004152591.1 | type-F conjugative transfer system protein TrbI | - |
| CS526_RS28730 () | 107171..109810 | - | 2640 | WP_004152592.1 | type IV secretion system protein TraC | - |
| CS526_RS28735 () | 109882..110280 | - | 399 | WP_004153071.1 | hypothetical protein | - |
| CS526_RS28745 () | 110576..110980 | - | 405 | WP_004152594.1 | hypothetical protein | - |
| CS526_RS28750 () | 111047..111364 | - | 318 | WP_004152595.1 | hypothetical protein | - |
| CS526_RS28755 () | 111365..111583 | - | 219 | WP_004171484.1 | hypothetical protein | - |
| CS526_RS28760 () | 111607..111897 | - | 291 | WP_004152596.1 | hypothetical protein | - |
| CS526_RS28765 () | 111902..112312 | - | 411 | WP_004152597.1 | lipase chaperone | - |
| CS526_RS28770 () | 112444..113013 | - | 570 | WP_004152598.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CS526_RS28775 () | 113036..113632 | - | 597 | WP_004152599.1 | conjugal transfer protein TraP | - |
| CS526_RS28780 () | 113625..115049 | - | 1425 | WP_004152600.1 | conjugal transfer protein TraB | - |
| CS526_RS28785 () | 115049..115789 | - | 741 | WP_004152601.1 | type-F conjugative transfer system secretin TraK | - |
| CS526_RS28790 () | 115776..116342 | - | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| CS526_RS28795 () | 116362..116667 | - | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| CS526_RS28800 () | 116681..117049 | - | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| CS526_RS28805 () | 117103..117474 | - | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| CS526_RS28810 () | 117558..118244 | - | 687 | WP_011977735.1 | transcriptional regulator TraJ family protein | - |
| CS526_RS28815 () | 118467..118859 | - | 393 | WP_004178062.1 | relaxosome protein TraM | - |
| CS526_RS28820 () | 119293..119778 | + | 486 | WP_004178063.1 | hypothetical protein | VF |
| CS526_RS28825 () | 119811..120140 | - | 330 | WP_011977736.1 | hypothetical protein | - |
| CS526_RS28830 () | 120173..120994 | - | 822 | WP_004178064.1 | DUF945 domain-containing protein | - |
| CS526_RS28850 () | 121828..122241 | - | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| CS526_RS28855 () | 122242..122520 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| CS526_RS28860 () | 122510..122830 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CS526_RS28865 () | 122911..123135 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| CS526_RS28870 () | 123146..123358 | - | 213 | WP_004152718.1 | hypothetical protein | - |
| CS526_RS28875 () | 123419..123775 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| CS526_RS28885 () | 124411..124761 | - | 351 | WP_004152758.1 | hypothetical protein | - |
| CS526_RS28890 () | 124758..125030 | - | 273 | WP_004152759.1 | hypothetical protein | - |
| CS526_RS28895 () | 125730..125891 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| CS526_RS28900 () | 125963..127042 | + | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| CS526_RS28910 () | 127220..127594 | - | 375 | WP_004152638.1 | hypothetical protein | - |
| CS526_RS28915 () | 127650..127976 | - | 327 | WP_004152639.1 | hypothetical protein | - |
| CS526_RS28920 () | 127973..128701 | - | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| CS526_RS28925 () | 128698..129129 | - | 432 | WP_004152641.1 | conjugation system SOS inhibitor PsiB | - |
| CS526_RS28930 () | 129196..131232 | - | 2037 | WP_004178066.1 | ParB/RepB/Spo0J family partition protein | - |
| CS526_RS28935 () | 131302..131550 | - | 249 | WP_004152643.1 | DUF905 domain-containing protein | - |
| CS526_RS28940 () | 131599..132141 | - | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| CS526_RS28955 () | 132917..133480 | - | 564 | WP_004152645.1 | methyltransferase | - |
| CS526_RS28960 () | 133528..134883 | - | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| CS526_RS28965 () | 134935..135165 | - | 231 | WP_099595318.1 | hypothetical protein | - |
| CS526_RS28970 () | 135257..135484 | - | 228 | WP_004178072.1 | hypothetical protein | - |
| CS526_RS28980 () | 136266..136583 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| CS526_RS28985 () | 136618..136872 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| CS526_RS28990 () | 137109..137534 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| CS526_RS29000 () | 138055..138285 | - | 231 | WP_004152753.1 | hypothetical protein | - |
| CS526_RS29005 () | 138519..140006 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| CS526_RS29015 () | 140409..140834 | + | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CS526_RS29020 () | 140834..142105 | + | 1272 | WP_004152715.1 | Y-family DNA polymerase | - |
| CS526_RS29025 () | 142184..142399 | + | 216 | Protein_159 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| CS526_RS29030 () | 142422..143620 | - | 1199 | Protein_160 | IS200-IS605 family transposase IS609 | Transposase |
| CS526_RS29045 () | 145057..146028 | - | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CS526_RS29050 () | 146028..147194 | - | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|