MGE detailed information

MGE type: Conjugative plasmid        MGE length: 196733 bp
Accession: NZ_CP023943        Location: 1..196733         Organism: Klebsiella pneumoniae strain FDAARGOS_444       Replicon: plasmid unnamed1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN70_RS29185 () 812..1447 - 636 WP_000470623.1 recombinase family protein -
CRN70_RS29190 () 1615..4602 + 2988 WP_000124025.1 Tn3 family transposase -
CRN70_RS29195 () 4632..4934 + 303 Protein_3 helix-turn-helix domain-containing protein -
CRN70_RS29200 () 4937..7903 + 2967 WP_001138064.1 Tn3-like element TnAs3 family transposase -
CRN70_RS29205 () 7912..8313 + 402 WP_046788546.1 hypothetical protein -
CRN70_RS29210 () 8398..9102 - 705 WP_001067784.1 IS6-like element IS1006 family transposase -
CRN70_RS29215 () 9166..9996 + 831 Protein_7 IS91-like element ISVsa3 family transposase -
CRN70_RS29220 () 10027..10911 + 885 WP_001447541.1 DUF3363 domain-containing protein -
CRN70_RS29225 () 11128..12342 + 1215 WP_000214122.1 chloramphenicol/florfenicol efflux MFS transporter FloR -
CRN70_RS29235 () 12616..12840 - 225 WP_000743213.1 hypothetical protein -
CRN70_RS29240 () 12837..13574 - 738 WP_001446887.1 recombinase family protein -
CRN70_RS31475 () 14060..14200 - 141 WP_001044210.1 hypothetical protein -
CRN70_RS29250 () 14206..14910 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
CRN70_RS29255 () 14973..15323 + 351 Protein_14 tyrosine-type recombinase/integrase -
CRN70_RS29260 () 15298..15606 - 309 Protein_15 DDE-type integrase/transposase/recombinase -
CRN70_RS29265 () 15623..16699 - 1077 WP_000227969.1 IS110 family transposase -
CRN70_RS29275 () 16981..17160 - 180 Protein_17 IS3 family transposase -
CRN70_RS29280 () 17241..18749 - 1509 WP_001189111.1 group II intron reverse transcriptase/maturase -
CRN70_RS29290 () 19422..20110 - 689 Protein_19 IS3 family transposase -
CRN70_RS29300 () 20636..20815 - 180 WP_006788217.1 hypothetical protein -
CRN70_RS29305 () 20935..21561 - 627 WP_004098977.1 ParA family plasmid-partitioning AAA ATPase -
CRN70_RS29310 () 22194..23069 - 876 WP_004098982.1 RepB family plasmid replication initiator protein -
CRN70_RS29315 () 23481..24107 - 627 Protein_23 DUF4113 domain-containing protein -
CRN70_RS29325 () 25384..26088 - 705 WP_020324562.1 IS6-like element IS26 family transposase -
CRN70_RS29335 () 27921..28607 + 687 WP_004201232.1 NYN domain-containing protein -
CRN70_RS29340 () 28745..29482 + 738 WP_004201234.1 hypothetical protein -
CRN70_RS29345 () 30002..31471 - 1470 WP_004201235.1 HNH endonuclease -
CRN70_RS29355 () 32228..32557 - 330 Protein_29 recombinase family protein -
CRN70_RS29365 () 32623..33327 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
CRN70_RS29375 () 33471..34112 - 642 WP_001011939.1 type A-2 chloramphenicol O-acetyltransferase CatII -
CRN70_RS29380 () 34262..34761 - 500 Protein_32 hypothetical protein -
CRN70_RS29385 () 34841..35545 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
CRN70_RS31480 () 35598..35843 - 246 Protein_34 recombinase family protein -
CRN70_RS29405 () 36236..37249 - 1014 WP_000845048.1 class 1 integron integrase IntI1 -
CRN70_RS29410 () 37541..38095 + 555 WP_063840321.1 fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5 -
CRN70_RS29415 () 38192..38644 + 453 WP_001749986.1 NAD(+)--rifampin ADP-ribosyltransferase Arr-3 -
CRN70_RS29420 () 38777..39250 + 474 WP_001749985.1 trimethoprim-resistant dihydrofolate reductase DfrA27 -
CRN70_RS29425 () 39431..40276 + 846 WP_001749984.1 ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA16 -
CRN70_RS29430 () 40393..40740 + 348 WP_000679427.1 quaternary ammonium compound efflux SMR transporter QacE delta 1 -
CRN70_RS29435 () 40734..41573 + 840 WP_000259031.1 sulfonamide-resistant dihydropteroate synthase Sul1 -
CRN70_RS29440 () 41978..42580 + 603 Protein_42 transposase zinc-binding domain-containing protein -
CRN70_RS29445 () 42631..43335 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
CRN70_RS29450 () 43541..43849 - 309 Protein_44 transposase -
CRN70_RS29455 () 44191..45018 + 828 WP_004153729.1 phosphonate ABC transporter ATP-binding protein -
CRN70_RS29460 () 45015..45878 + 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
CRN70_RS29465 () 45887..46714 + 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
CRN70_RS29470 () 46723..47733 + 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
CRN70_RS29475 () 47727..48596 + 870 WP_004152692.1 LysR family transcriptional regulator -
CRN70_RS29480 () 48704..49223 + 520 Protein_50 IS5-like element ISPre2 family transposase -
CRN70_RS29495 () 49805..50785 - 981 WP_000019473.1 IS5-like element ISKpn26 family transposase -
CRN70_RS29500 () 51044..51741 - 698 Protein_52 IS1 family transposase -
CRN70_RS29505 () 51926..52042 - 117 Protein_53 transposase domain-containing protein -
CRN70_RS30835 () 51987..52250 - 264 WP_004118209.1 transposase -
CRN70_RS30840 () 52265..52528 + 264 WP_004118208.1 hypothetical protein -
CRN70_RS29515 () 52772..53053 + 282 WP_004152118.1 helix-turn-helix domain-containing protein -
CRN70_RS29520 () 53088..53657 + 570 WP_004152117.1 small heat shock protein sHSP20 -
CRN70_RS29525 () 53772..56567 + 2796 WP_098977952.1 heat shock survival AAA family ATPase ClpK -
CRN70_RS29530 () 56567..56764 + 198 WP_004152115.1 hypothetical protein -
CRN70_RS29540 () 57002..57751 + 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
CRN70_RS29545 () 57738..58700 + 963 WP_004152113.1 M48 family metalloprotease -
CRN70_RS29550 () 58788..60042 + 1255 Protein_62 IS3 family transposase -
CRN70_RS29555 () 60543..61889 - 1347 WP_020314316.1 ISNCY family transposase -
CRN70_RS29560 () 62101..62583 - 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
CRN70_RS29565 () 62571..62837 - 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
CRN70_RS29570 () 63013..63267 - 255 WP_004152108.1 hypothetical protein -
CRN70_RS29575 () 63343..63600 - 258 WP_004152107.1 hypothetical protein -
CRN70_RS29580 () 63649..63852 - 204 WP_004152106.1 hemolysin expression modulator Hha -
CRN70_RS29585 () 63886..64254 - 369 WP_004152105.1 hypothetical protein -
CRN70_RS29590 () 64298..64792 - 495 WP_004152104.1 DNA-binding protein -
CRN70_RS29595 () 64823..65398 - 576 WP_004152103.1 hypothetical protein -
CRN70_RS29600 () 65386..65655 - 270 WP_004152102.1 hypothetical protein -
CRN70_RS29605 () 66013..66363 + 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
CRN70_RS29610 () 66413..66775 + 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
CRN70_RS29615 () 66793..68544 + 1752 WP_004152099.1 arsenite efflux transporter ATPase subunit ArsA -
CRN70_RS29620 () 68592..69881 + 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
CRN70_RS29625 () 69894..70319 + 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
CRN70_RS29630 () 70352..70888 - 537 WP_004152096.1 GNAT family N-acetyltransferase -
CRN70_RS29635 () 71010..72760 - 1751 Protein_79 arsenical pump-driving ATPase -
CRN70_RS29640 () 72785..73147 - 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
CRN70_RS29645 () 73223..73768 - 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
CRN70_RS29650 () 73777..74490 - 714 WP_004152093.1 arsenical resistance protein ArsH -
CRN70_RS29655 () 74487..74813 - 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
CRN70_RS29660 () 75145..75642 + 498 WP_004152091.1 GNAT family N-acetyltransferase -
CRN70_RS29665 () 75692..76201 - 510 WP_031944101.1 aquaporin -
CRN70_RS29670 () 76263..77883 + 1621 Protein_86 ISL3 family transposase -
CRN70_RS29675 () 77944..78123 + 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
CRN70_RS29680 () 78355..78789 - 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
CRN70_RS29685 () 79006..80406 - 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
CRN70_RS29690 () 80403..81083 - 681 WP_001188930.1 copper response regulator transcription factor PcoR -
CRN70_RS29695 () 81138..82067 - 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
CRN70_RS29700 () 82072..82452 - 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
CRN70_RS29705 () 82492..83382 - 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
CRN70_RS29710 () 83388..85205 - 1818 WP_000925242.1 multicopper oxidase PcoA -
CRN70_RS29715 () 85439..85888 + 450 WP_001023257.1 copper resistance protein -
CRN70_RS29720 () 86177..86914 + 738 WP_004118669.1 peptidoglycan DD-metalloendopeptidase family protein -
CRN70_RS29725 () 86948..87145 - 198 WP_000843497.1 DUF2933 domain-containing protein -
CRN70_RS29730 () 87186..89633 - 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
CRN70_RS29735 () 89760..90200 - 441 WP_000758228.1 hypothetical protein -
CRN70_RS29740 () 90287..93433 - 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
CRN70_RS29745 () 93444..94736 - 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
CRN70_RS29750 () 94850..95203 - 354 WP_001246153.1 cation efflux system protein CusF -
CRN70_RS29755 () 95232..96617 - 1386 WP_000475512.1 Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC -
CRN70_RS29760 () 96807..97487 + 681 WP_001572351.1 copper/silver response regulator transcription factor SilR -
CRN70_RS29765 () 97480..98955 + 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
CRN70_RS29770 () 99206..99637 + 432 WP_004178091.1 silver-binding protein SilE -
CRN70_RS29775 () 99933..100475 - 543 Protein_107 transposase -
CRN70_RS29780 () 100491..100975 - 485 Protein_108 IS1 family transposase -
CRN70_RS29785 () 101066..102273 + 1208 WP_085955172.1 IS3 family transposase -
CRN70_RS29795 () 102464..103161 + 698 Protein_110 IS1 family transposase -
CRN70_RS29800 () 103313..105310 + 1998 WP_004178088.1 choline BCCT transporter BetT -
CRN70_RS29805 () 105373..106650 + 1278 WP_004152070.1 DUF2254 domain-containing protein -
CRN70_RS29810 () 107633..109087 - 1455 WP_020444838.1 EAL domain-containing protein -
CRN70_RS29815 () 109689..109946 + 258 WP_004197688.1 hypothetical protein -
CRN70_RS29820 () 110619..111587 - 969 WP_011977741.1 IS5 family transposase -
CRN70_RS29825 () 111607..111918 + 312 WP_071527918.1 EAL domain-containing protein -
CRN70_RS29830 () 111945..112892 - 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
CRN70_RS29835 () 114036..114776 + 741 WP_001515717.1 tyrosine-type recombinase/integrase -
CRN70_RS29845 () 115493..116503 - 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
CRN70_RS29850 () 117255..118421 + 1167 WP_000523813.1 plasmid-partitioning protein SopA -
CRN70_RS29855 () 118421..119392 + 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
CRN70_RS29870 () 120829..122027 + 1199 Protein_122 IS200/IS605 family element transposase accessory protein TnpB -
CRN70_RS29875 () 122050..122265 - 216 Protein_123 type II toxin-antitoxin system Phd/YefM family antitoxin -
CRN70_RS29880 () 122344..123615 - 1272 WP_004152715.1 Y-family DNA polymerase -
CRN70_RS29885 () 123615..124040 - 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
CRN70_RS29895 () 124443..125930 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
CRN70_RS29900 () 126164..126394 + 231 WP_004152753.1 hypothetical protein -
CRN70_RS29910 () 126915..127340 + 426 WP_004118478.1 antirestriction protein -
CRN70_RS29915 () 127577..127831 + 255 WP_004152754.1 DNA polymerase III subunit theta -
CRN70_RS29920 () 127866..128183 + 318 WP_004118473.1 hypothetical protein -
CRN70_RS29935 () 128965..129192 + 228 WP_004178072.1 hypothetical protein -
CRN70_RS29940 () 129284..129514 + 231 WP_004198570.1 hypothetical protein -
CRN70_RS29945 () 129566..130921 + 1356 WP_004178068.1 DUF3560 domain-containing protein -
CRN70_RS29950 () 130969..131532 + 564 WP_004152645.1 methyltransferase -
CRN70_RS29965 () 132308..132850 + 543 WP_004152644.1 single-stranded DNA-binding protein -
CRN70_RS29970 () 132899..133147 + 249 WP_004152643.1 DUF905 domain-containing protein -
CRN70_RS29975 () 133217..135253 + 2037 WP_004178066.1 ParB/RepB/Spo0J family partition protein -
CRN70_RS29980 () 135320..135751 + 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
CRN70_RS29985 () 135748..136476 + 729 WP_004152640.1 plasmid SOS inhibition protein A -
CRN70_RS29990 () 136473..136799 + 327 WP_004152639.1 hypothetical protein -
CRN70_RS29995 () 136855..137229 + 375 WP_004152638.1 hypothetical protein -
CRN70_RS30005 () 137407..138486 - 1080 WP_004220208.1 IS481-like element ISKpn28 family transposase -
CRN70_RS30010 () 138558..138719 + 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
CRN70_RS30015 () 139419..139691 + 273 WP_004152759.1 hypothetical protein -
CRN70_RS30020 () 139688..140038 + 351 WP_004152758.1 hypothetical protein -
CRN70_RS30035 () 140674..141030 + 357 WP_004152717.1 hypothetical protein -
CRN70_RS30040 () 141091..141303 + 213 WP_004152718.1 hypothetical protein -
CRN70_RS30045 () 141314..141538 + 225 WP_004152719.1 hypothetical protein -
CRN70_RS30050 () 141619..141939 + 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
CRN70_RS30055 () 141929..142207 + 279 WP_004152721.1 helix-turn-helix domain-containing protein -
CRN70_RS30060 () 142208..142621 + 414 WP_004152722.1 helix-turn-helix domain-containing protein -
CRN70_RS30085 () 143455..144276 + 822 WP_004178064.1 DUF945 domain-containing protein -
CRN70_RS30090 () 144309..144638 + 330 WP_011977736.1 hypothetical protein -
CRN70_RS30095 () 144671..145156 - 486 WP_004178063.1 transglycosylase SLT domain-containing protein -
CRN70_RS30100 () 145590..145982 + 393 WP_004178062.1 relaxosome protein TraM -
CRN70_RS30105 () 146205..146891 + 687 WP_011977735.1 transcriptional regulator TraJ family protein -
CRN70_RS30110 () 146975..147346 + 372 WP_004208838.1 TraY domain-containing protein -
CRN70_RS30115 () 147400..147768 + 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
CRN70_RS30120 () 147782..148087 + 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
CRN70_RS30125 () 148107..148673 + 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
CRN70_RS30130 () 148660..149400 + 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
CRN70_RS30135 () 149400..150824 + 1425 WP_004152600.1 conjugal transfer protein TraB -
CRN70_RS30140 () 150817..151413 + 597 WP_004152599.1 conjugal transfer protein TraP -
CRN70_RS30145 () 151436..152005 + 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
CRN70_RS30150 () 152137..152547 + 411 WP_004152597.1 lipase chaperone -
CRN70_RS30155 () 152552..152842 + 291 WP_004152596.1 hypothetical protein -
CRN70_RS30160 () 152866..153084 + 219 WP_004171484.1 hypothetical protein -
CRN70_RS30165 () 153085..153402 + 318 WP_004152595.1 hypothetical protein -
CRN70_RS30170 () 153469..153873 + 405 WP_004152594.1 hypothetical protein -
CRN70_RS30180 () 154169..154567 + 399 WP_004153071.1 hypothetical protein -
CRN70_RS30185 () 154639..157278 + 2640 WP_004152592.1 type IV secretion system protein TraC -
CRN70_RS30190 () 157278..157667 + 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
CRN70_RS30195 () 157667..158293 + 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
CRN70_RS30200 () 158304..159296 + 993 WP_004178057.1 conjugal transfer pilus assembly protein TraU -
CRN70_RS30205 () 159309..159947 + 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
CRN70_RS30210 () 159995..161950 + 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CRN70_RS30215 () 161982..162218 + 237 WP_004152683.1 conjugal transfer protein TrbE -
CRN70_RS30225 () 162446..162772 + 327 WP_004152685.1 hypothetical protein -
CRN70_RS30230 () 162793..163545 + 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
CRN70_RS30235 () 163556..163795 + 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
CRN70_RS30240 () 163767..164339 + 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CRN70_RS30245 () 164332..164760 + 429 WP_004152689.1 hypothetical protein -
CRN70_RS30250 () 164747..166117 + 1371 WP_004178055.1 conjugal transfer protein TraH -
CRN70_RS30255 () 166117..168966 + 2850 WP_004178054.1 conjugal transfer mating pair stabilization protein TraG -
CRN70_RS30260 () 168972..169499 + 528 WP_004153030.1 hypothetical protein -
CRN70_RS30265 () 169689..170420 + 732 WP_004152629.1 complement resistance protein TraT -
CRN70_RS30270 () 170780..173089 + 2310 Protein_187 type IV conjugative transfer system coupling protein TraD -
CRN70_RS30275 () 173089..178350 + 5262 WP_004153029.1 conjugative transfer relaxase/helicase TraI -
CRN70_RS30280 () 178430..179155 + 726 WP_004152303.1 type-F conjugative transfer system pilin acetylase TraX -
CRN70_RS30285 () 179313..179909 + 597 WP_004178053.1 fertility inhibition protein FinO -
CRN70_RS30290 () 179929..180276 + 348 WP_004152301.1 hypothetical protein -
CRN70_RS30295 () 180491..181036 - 546 WP_004178052.1 hypothetical protein -
CRN70_RS30305 () 181393..183714 + 2322 WP_004178051.1 klebicin B-related nuclease bacteriocin -
CRN70_RS30310 () 183716..183994 + 279 WP_004152296.1 bacteriocin immunity protein -
CRN70_RS30315 () 184335..184814 + 480 WP_009485932.1 phospholipase D family protein -
CRN70_RS30320 () 185135..185413 + 279 WP_004199332.1 replication regulatory protein RepA -
CRN70_RS30325 () 185630..185707 + 78 WP_004171457.1 RepA leader peptide Tap -
CRN70_RS30330 () 185700..186557 + 858 WP_004152292.1 incFII family plasmid replication initiator RepA -
CRN70_RS30345 () 187756..188604 - 849 Protein_199 hypothetical protein -
CRN70_RS30350 () 188816..189352 + 537 Protein_200 PAS domain-containing protein -
CRN70_RS30355 () 189420..190517 - 1098 Protein_201 TonB-dependent receptor -
CRN70_RS30360 () 190574..191540 - 967 Protein_202 IS5 family transposase -
CRN70_RS30365 () 191575..192450 - 876 WP_032277257.1 class A extended-spectrum beta-lactamase CTX-M-27 -
CRN70_RS30370 () 192700..193962 - 1263 WP_000608644.1 IS1380-like element ISEc9 family transposase -
CRN70_RS30375 () 194203..194460 + 258 Protein_205 recombinase family protein -
CRN70_RS30380 () 194762..195037 + 276 WP_001141270.1 formaldehyde-responsive transcriptional repressor FrmR -
CRN70_RS30385 () 195068..196177 + 1110 WP_000842086.1 S-(hydroxymethyl)glutathione dehydrogenase -
CRN70_RS30390 () 196219..196617 + 399 WP_008813494.1 VOC family protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance