NZ_CP0238051..201207

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 201207 bp
Accession: NZ_CP023805        Location: 1..201207         Organism: Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate       Replicon: plasmid pER04619.3A.1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO999_RS14815 () 1..1041 + 1041 WP_002303636.1 replication initiator protein A -
CO999_RS14820 () 1865..2197 + 333 WP_002323647.1 hypothetical protein -
CO999_RS14825 () 2816..3157 + 342 WP_002295674.1 DUF5406 domain-containing protein -
CO999_RS14830 () 3394..4644 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CO999_RS14835 () 5054..7426 + 2373 WP_002305801.1 hypothetical protein -
CO999_RS14840 () 7487..8947 + 1461 WP_002347152.1 toprim domain-containing protein -
CO999_RS14845 () 8958..11162 + 2205 WP_002305772.1 type IA DNA topoisomerase -
CO999_RS16265 () 11178..11327 + 150 WP_002303309.1 hypothetical protein -
CO999_RS14850 () 11403..11996 + 594 WP_002303311.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CO999_RS14855 () 12009..12908 + 900 WP_002303312.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO999_RS14860 () 12911..13384 + 474 WP_002321302.1 single-stranded DNA-binding protein -
CO999_RS14865 () 13750..14010 + 261 WP_002321303.1 hypothetical protein -
CO999_RS14870 () 14455..14661 + 207 WP_002296239.1 hypothetical protein -
CO999_RS14875 () 14661..14912 + 252 WP_002305766.1 hypothetical protein -
CO999_RS14880 () 14928..15344 + 417 WP_002305764.1 hypothetical protein -
CO999_RS14885 () 15326..15598 + 273 WP_002348912.1 hypothetical protein -
CO999_RS14890 () 15765..16166 + 402 WP_002305759.1 IS200-IS605 family transposase ISCpe2 Transposase
CO999_RS14895 () 16178..17323 + 1146 WP_002305757.1 IS200-IS605 family transposase ISEfa4 Transposase
CO999_RS14900 () 17561..17824 + 264 WP_002287514.1 hypothetical protein Antitoxin Detail
CO999_RS14905 () 17818..18168 + 351 WP_002321032.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
CO999_RS14910 () 18192..18806 - 615 WP_002318230.1 Tn3 family transposase TnpR_TnAs2 Transposase
CO999_RS14915 () 19256..20581 + 1326 WP_002348911.1 Y-family DNA polymerase -
CO999_RS14920 () 20574..20924 + 351 WP_002303114.1 hypothetical protein -
CO999_RS14925 () 20921..21100 + 180 WP_002322386.1 hypothetical protein -
CO999_RS14930 () 21112..21405 + 294 WP_002322251.1 hypothetical protein -
CO999_RS14935 () 21631..22449 + 819 WP_002305212.1 ParA family protein -
CO999_RS14940 () 22468..22875 + 408 WP_002305774.1 hypothetical protein -
CO999_RS14945 () 23195..24280 + 1086 WP_002322387.1 replication initiator protein A -
CO999_RS14950 () 25117..25449 + 333 WP_002310954.1 hypothetical protein -
CO999_RS14955 () 26040..26369 + 330 WP_002296227.1 hypothetical protein -
CO999_RS14960 () 26356..26697 + 342 WP_010782601.1 DUF5406 domain-containing protein -
CO999_RS14965 () 26811..27050 + 240 WP_002299885.1 hypothetical protein -
CO999_RS14970 () 27117..27356 + 240 WP_002299886.1 hypothetical protein -
CO999_RS14975 () 27483..28172 + 690 WP_002299887.1 sortase -
CO999_RS14980 () 28178..29344 + 1167 WP_002299888.1 EpaQ family protein -
CO999_RS14985 () 29426..30097 + 672 WP_002302875.1 class A sortase -
CO999_RS14990 () 30150..32126 + 1977 WP_002302873.1 isopeptide-forming domain-containing fimbrial protein -
CO999_RS14995 () 32139..32891 + 753 WP_002302871.1 hypothetical protein VF
CO999_RS15000 () 32907..33668 + 762 WP_002302869.1 hypothetical protein -
CO999_RS15005 () 33681..33941 + 261 WP_002302867.1 hypothetical protein -
CO999_RS15010 () 33938..36028 + 2091 WP_002305780.1 isopeptide-forming domain-containing fimbrial protein -
CO999_RS15015 () 36064..38121 - 2058 WP_002300034.1 Beta-L-arabinobiosidase VF
CO999_RS15020 () 38266..38457 - 192 WP_002300033.1 hypothetical protein -
CO999_RS15025 () 38645..39100 + 456 WP_002300032.1 hypothetical protein -
CO999_RS15030 () 39097..39339 + 243 WP_002305782.1 DUF5415 family protein -
CO999_RS15035 () 39357..39659 + 303 WP_002302862.1 hypothetical protein -
CO999_RS15040 () 39728..41782 + 2055 WP_002302860.1 hypothetical protein -
CO999_RS15045 () 41782..44394 + 2613 WP_002302859.1 type IV secretory system conjugative DNA transfer family protein -
CO999_RS15050 () 44391..46769 + 2379 WP_002302858.1 hypothetical protein -
CO999_RS15055 () 46830..47372 + 543 WP_002302857.1 hypothetical protein -
CO999_RS15060 () 47450..47782 + 333 WP_002302856.1 hypothetical protein -
CO999_RS15065 () 47783..48376 + 594 WP_002302855.1 hypothetical protein -
CO999_RS15070 () 48398..50422 + 2025 WP_002302854.1 hypothetical protein -
CO999_RS15075 () 50422..51621 + 1200 WP_002302853.1 glucosaminidase domain-containing protein -
CO999_RS15080 () 51637..52281 + 645 WP_002302852.1 hypothetical protein -
CO999_RS15085 () 52292..53098 + 807 WP_002302851.1 hypothetical protein -
CO999_RS15090 () 53121..53350 + 230 Protein_56 hypothetical protein -
CO999_RS15095 () 53371..54444 + 1074 WP_002296375.1 DUF4199 domain-containing protein -
CO999_RS15100 () 54488..54757 + 270 WP_002305788.1 hypothetical protein -
CO999_RS15105 () 55033..55308 + 276 WP_002302849.1 hypothetical protein -
CO999_RS15110 () 55350..55772 + 423 WP_002302844.1 hypothetical protein -
CO999_RS15115 () 55792..57384 + 1593 WP_033582318.1 hypothetical protein Relaxase
CO999_RS15120 () 57405..57740 + 336 WP_002302842.1 hypothetical protein -
CO999_RS15125 () 57886..58080 + 195 WP_002302840.1 hypothetical protein -
CO999_RS15130 () 58216..59466 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CO999_RS15135 () 59876..62248 + 2373 WP_002305801.1 hypothetical protein -
CO999_RS15140 () 62323..63777 + 1455 WP_087121894.1 toprim domain-containing protein -
CO999_RS15145 () 63788..65797 + 2010 WP_002303486.1 DNA topoisomerase III -
CO999_RS16270 () 65913..66062 + 150 WP_002295632.1 hypothetical protein -
CO999_RS15155 () 66143..66739 + 597 WP_002303484.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CO999_RS15160 () 66752..67651 + 900 WP_002303483.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO999_RS15165 () 67654..67785 + 132 WP_002301801.1 single-stranded DNA-binding protein -
CO999_RS15170 () 67807..68139 + 333 WP_002305808.1 single-stranded DNA-binding protein -
CO999_RS15175 () 68184..68417 + 234 WP_002303482.1 hypothetical protein -
CO999_RS15180 () 68576..68698 - 123 WP_002295624.1 putative holin-like toxin -
CO999_RS15185 () 68888..69112 + 225 WP_002305809.1 hypothetical protein -
CO999_RS15195 () 69555..69761 + 207 WP_002305810.1 hypothetical protein -
CO999_RS15200 () 69761..70012 + 252 WP_002300797.1 hypothetical protein -
CO999_RS16275 () 70028..70183 + 156 WP_002300799.1 hypothetical protein -
CO999_RS15205 () 70193..70465 + 273 WP_002300801.1 hypothetical protein -
CO999_RS15215 () 70910..71089 + 180 WP_002300804.1 hypothetical protein -
CO999_RS15220 () 71148..71504 + 357 WP_002311569.1 hypothetical protein -
CO999_RS15230 () 72473..73426 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CO999_RS15235 () 73547..73810 + 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
CO999_RS15245 () 74182..75360 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO999_RS15250 () 75892..76800 + 909 WP_002332708.1 IS982 family transposase ISEfm1 Transposase
CO999_RS15255 () 76820..78742 + 1923 Protein_86 PTS sugar transporter subunit IIA -
CO999_RS15260 () 78745..79200 + 456 WP_002300835.1 PTS sugar transporter subunit IIA -
CO999_RS15265 () 79214..80542 + 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
CO999_RS15270 () 80576..80860 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
CO999_RS15275 () 80862..81377 + 516 WP_002300840.1 YjbQ family protein -
CO999_RS15280 () 81393..82055 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
CO999_RS15285 () 82062..82634 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
CO999_RS15290 () 82806..84353 - 1548 WP_002303202.1 IS66 family transposase ISRob1 Transposase
CO999_RS15295 () 84455..84808 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CO999_RS15300 () 84798..84992 - 195 WP_002285758.1 hypothetical protein -
CO999_RS15305 () 85174..86694 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
CO999_RS15315 () 86937..87122 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
CO999_RS15320 () 87106..87288 - 183 WP_002300846.1 hypothetical protein -
CO999_RS15325 () 87529..87747 + 219 Protein_99 IS256 family transposase ISLgar5 Transposase
CO999_RS15330 () 88242..88841 + 600 WP_002301839.1 Tyrosine recombinase XerD VF
CO999_RS15335 () 88905..89504 + 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
CO999_RS15340 () 89534..90185 - 652 Protein_102 IS6 family transposase IS1216V Transposase
CO999_RS15345 () 90520..91392 - 873 WP_002305879.1 ROK family protein -
CO999_RS15350 () 91635..92807 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
CO999_RS15355 () 92988..94934 - 1947 WP_002303302.1 sucrose-specific PTS transporter subunit IIBC -
CO999_RS15360 () 95119..96558 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
CO999_RS15365 () 96560..97522 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
CO999_RS15375 () 99361..99816 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
CO999_RS15385 () 100081..100179 + 99 Protein_110 IS30 family transposase -
CO999_RS15390 () 100402..100632 - 231 WP_002289255.1 resolvase -
CO999_RS15395 () 100862..101680 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
CO999_RS15400 () 101841..102530 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
CO999_RS15405 () 102544..104046 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
CO999_RS15410 () 104059..104535 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
CO999_RS16115 () 104632..104742 - 111 Protein_116 transposase -
CO999_RS15430 () 107313..107831 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
CO999_RS15445 () 109907..110992 + 1086 WP_002301591.1 tyrosine recombinase XerS -
CO999_RS15450 () 111100..112053 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CO999_RS15455 () 112184..113005 - 822 Protein_121 PTS sugar transporter subunit IIC -
CO999_RS15460 () 113135..114454 + 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
CO999_RS15465 () 114660..115118 - 459 Protein_123 PTS sugar transporter subunit IIC -
CO999_RS15470 () 115137..115622 - 486 Protein_124 haloacid dehalogenase-like hydrolase -
CO999_RS15475 () 115717..116895 + 1179 WP_002324322.1 IS256 family transposase ISEfm2 Transposase
CO999_RS15480 () 116923..117396 - 474 Protein_126 haloacid dehalogenase-like hydrolase -
CO999_RS15485 () 117475..118470 - 996 WP_002301128.1 tagatose-bisphosphate aldolase -
CO999_RS15490 () 118486..119655 - 1170 WP_002301130.1 SIS domain-containing protein -
CO999_RS15495 () 119671..120405 - 735 WP_002301131.1 GntR family transcriptional regulator -
CO999_RS15505 () 122907..124199 - 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
CO999_RS15510 () 124473..124733 - 261 WP_002313174.1 hypothetical protein -
CO999_RS15515 () 124984..126162 + 1179 WP_002346943.1 IS256 family transposase ISEf1 Transposase
CO999_RS15520 () 126514..126810 + 297 WP_073120200.1 IS3 family transposase -
CO999_RS15525 () 126733..127557 - 825 Protein_135 transposase -
CO999_RS15530 () 127759..128154 - 396 WP_002287876.1 aspartate 1-decarboxylase -
CO999_RS15535 () 128164..129012 - 849 WP_002287875.1 pantoate--beta-alanine ligase -
CO999_RS15540 () 129027..129854 - 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
CO999_RS15545 () 129866..130726 - 861 Protein_139 DUF2520 domain-containing protein -
CO999_RS15550 () 130925..131119 + 195 WP_002285758.1 hypothetical protein -
CO999_RS15555 () 131109..131462 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CO999_RS15560 () 131564..133111 + 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
CO999_RS15565 () 133317..134486 + 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
CO999_RS15570 () 134826..135506 - 681 WP_010782692.1 IS6 family transposase IS1216E Transposase
CO999_RS15575 () 136136..137308 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
CO999_RS15580 () 137559..138878 + 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
CO999_RS15585 () 139122..139862 - 741 Protein_147 APH(2'')-Ia/If/Ih family aminoglycoside O-phosphotransferase -
CO999_RS15590 () 139970..141148 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO999_RS15595 () 141115..141778 - 664 Protein_149 GNAT family N-acetyltransferase -
CO999_RS15600 () 141833..142009 - 177 Protein_150 IS6 family transposase IS1216V Transposase
CO999_RS15605 () 142169..143716 - 1548 WP_158294579.1 IS3 family transposase ISPa31 Transposase
CO999_RS15610 () 143786..144040 - 255 Protein_152 replication initiation protein -
CO999_RS15615 () 144716..145267 - 552 WP_002303113.1 DUF334 domain-containing protein -
CO999_RS15620 () 145362..145742 - 381 Protein_154 IS6 family transposase IS1216V Transposase
CO999_RS15630 () 145812..146492 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
CO999_RS15635 () 146520..147083 + 564 WP_002304893.1 Tn3 family transposase TnpR_ISPa40 Transposase
CO999_RS15640 () 147128..147295 - 168 WP_000824191.1 hypothetical protein -
CO999_RS15645 () 147329..147628 - 300 WP_000366408.1 BRCT domain-containing protein -
CO999_RS15650 () 147669..148286 - 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
CO999_RS15655 () 148611..149006 - 396 WP_002304891.1 hypothetical protein -
CO999_RS15660 () 149086..151437 - 2352 WP_000344083.1 DUF1906 domain-containing protein -
CO999_RS15665 () 151562..152251 - 690 WP_000718009.1 hypothetical protein -
CO999_RS15670 () 152265..152717 - 453 WP_000751236.1 hypothetical protein -
CO999_RS15675 () 152848..153528 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CO999_RS15685 () 154147..154350 - 204 WP_002348841.1 hypothetical protein -
CO999_RS15695 () 154809..155774 - 966 WP_002305972.1 Replication initiation protein Relaxase
CO999_RS15700 () 155854..156534 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CO999_RS15705 () 156636..157517 - 882 Protein_168 HAMP domain-containing histidine kinase -
CO999_RS15710 () 157620..158792 + 1173 WP_002316137.1 IS256 family transposase IS256 Transposase
CO999_RS15715 () 159429..159838 - 410 Protein_170 IS200-IS605 family transposase ISAac1 Transposase
CO999_RS15725 () 160072..160935 - 864 WP_101701477.1 triphosphoribosyl-dephospho-CoA synthase CitG -
CO999_RS15730 () 160928..161485 - 558 WP_002305953.1 citrate lyase holo-[acyl-carrier protein] synthase -
CO999_RS15735 () 161482..163041 - 1560 WP_002303161.1 citrate lyase subunit alpha -
CO999_RS15740 () 163034..163939 - 906 WP_002303160.1 citrate (pro-3S)-lyase subunit beta -
CO999_RS15745 () 163944..164237 - 294 WP_002303159.1 citrate lyase acyl carrier protein -
CO999_RS15750 () 164241..165254 - 1014 WP_002303158.1 [citrate (pro-3S)-lyase] ligase -
CO999_RS15755 () 165280..166584 - 1305 WP_002303157.1 2-hydroxycarboxylate transporter family protein -
CO999_RS15760 () 166565..167752 - 1188 WP_002303156.1 NADP-dependent malic enzyme -
CO999_RS15765 () 167941..168888 + 948 WP_002303155.1 DNA-binding transcriptional regulator -
CO999_RS15770 () 169185..169733 - 549 WP_002292681.1 hypothetical protein -
CO999_RS15775 () 169734..170591 - 858 WP_002292680.1 AAA family ATPase -
CO999_RS15780 () 170877..171164 - 288 WP_002313074.1 type II toxin-antitoxin system RelE/ParE family toxin -
CO999_RS15785 () 171154..171483 - 330 WP_002292678.1 AbrB family transcriptional regulator -
CO999_RS15790 () 171632..172312 - 681 Protein_184 IS6 family transposase IS1216V Transposase
CO999_RS15795 () 172386..172667 - 282 Protein_185 YfbU family protein -
CO999_RS15800 () 173129..174511 + 1383 Protein_186 IS3 family transposase ISLca1 Transposase
CO999_RS15805 () 174747..175619 - 873 WP_016171159.1 ROK family protein -
CO999_RS15810 () 175636..177108 - 1473 WP_002322556.1 glycoside hydrolase family 32 protein -
CO999_RS15815 () 177122..177970 - 849 WP_002313079.1 carbohydrate ABC transporter permease -
CO999_RS15820 () 177967..178833 - 867 WP_002348858.1 sugar ABC transporter permease -
CO999_RS15825 () 178876..180189 - 1314 WP_016171161.1 sugar ABC transporter substrate-binding protein -
CO999_RS15830 () 180329..181300 - 972 WP_016171162.1 LacI family DNA-binding transcriptional regulator -
CO999_RS15835 () 181426..181653 - 228 Protein_193 IS110 family transposase -
CO999_RS15840 () 181818..182153 - 336 Protein_194 Tn3 family transposase TnpA_ISXc4 Transposase
CO999_RS15845 () 182335..182940 + 606 WP_002313084.1 Tn3 family transposase TnpR_ISPa40 Transposase
CO999_RS15850 () 182986..183165 - 180 WP_002340501.1 IS21 family transposase ISAar36 Transposase
CO999_RS15855 () 183652..183852 - 201 Protein_197 hypothetical protein -
CO999_RS16120 () 184391..184662 - 272 Protein_198 HAD-IA family hydrolase -
CO999_RS15865 () 184773..185681 + 909 WP_016171164.1 IS982 family transposase ISEfm1 Transposase
CO999_RS15870 () 185740..187542 - 1803 WP_002342383.1 3'-5' exoribonuclease -
CO999_RS15875 () 187605..188447 - 843 WP_002342384.1 hypothetical protein -
CO999_RS15880 () 188463..188684 - 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
CO999_RS15885 () 188827..189105 - 279 Protein_203 site-specific recombinase -
CO999_RS15890 () 189180..189860 + 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
CO999_RS15895 () 189918..191138 - 1221 WP_002339142.1 PAS domain-containing protein -
CO999_RS15900 () 191158..191769 - 612 WP_002339141.1 NAD(P)H-dependent oxidoreductase -
CO999_RS15905 () 191812..192744 - 933 WP_002339140.1 FAD:protein FMN transferase -
CO999_RS15910 () 193169..194026 - 858 WP_002339139.1 helix-turn-helix domain-containing protein -
CO999_RS15915 () 194173..194853 - 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
CO999_RS15920 () 194966..195154 - 189 WP_002296843.1 hypothetical protein -
CO999_RS15925 () 195299..195979 - 681 WP_010782695.1 IS6 family transposase IS1216V Transposase
CO999_RS15930 () 196455..196772 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
CO999_RS15935 () 196773..197027 - 255 WP_002303208.1 hypothetical protein -
CO999_RS15940 () 197386..197790 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
CO999_RS15945 () 197807..198955 + 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
CO999_RS15950 () 199178..199396 - 219 Protein_216 type II toxin-antitoxin system RelE/ParE family toxin -
CO999_RS15955 () 199662..199856 - 195 WP_002348857.1 hypothetical protein -
CO999_RS16280 () 199956..200042 - 87 Protein_218 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance