MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 129878 bp
Accession: NZ_CP023804 Location: 95898..225775 Organism: Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate Replicon: chromosome
Accession: NZ_CP023804 Location: 95898..225775 Organism: Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CO999_RS00515 () | 91000..91188 | - | 189 | WP_002290463.1 | 50S ribosomal protein L28 | - |
| CO999_RS00525 () | 91458..91820 | + | 363 | WP_002294298.1 | Asp23/Gls24 family envelope stress response protein | - |
| CO999_RS00530 () | 91872..93554 | + | 1683 | WP_002301169.1 | DAK2 domain-containing protein | - |
| CO999_RS00535 () | 93671..95707 | + | 2037 | WP_002301167.1 | ATP-dependent DNA helicase RecG | - |
| CO999_RS00540 () | 95756..96757 | + | 1002 | WP_002289721.1 | phosphate acyltransferase PlsX | - |
| CO999_RS00545 () | 96879..97121 | + | 243 | WP_002294295.1 | Acyl carrier protein | VF |
| CO999_RS00550 () | 97389..98393 | + | 1005 | WP_002287889.1 | Oligopeptide transport ATP-binding protein OppD | VF |
| CO999_RS00555 () | 98394..99338 | + | 945 | WP_002287891.1 | Oligopeptide transport ATP-binding protein OppF | VF |
| CO999_RS00560 () | 99338..100300 | + | 963 | WP_002287892.1 | ABC transporter permease | - |
| CO999_RS00565 () | 100327..101241 | + | 915 | WP_002287893.1 | ABC transporter permease | - |
| CO999_RS00570 () | 101267..103048 | + | 1782 | WP_002287894.1 | oligopeptide ABC transporter substrate-binding protein | - |
| CO999_RS00580 () | 103396..104082 | + | 687 | WP_002287896.1 | ribonuclease III | - |
| CO999_RS00585 () | 104102..107683 | + | 3582 | WP_002301166.1 | chromosome segregation protein SMC | - |
| CO999_RS00590 () | 107692..108501 | + | 810 | WP_002348798.1 | Cof-type HAD-IIB family hydrolase | - |
| CO999_RS00595 () | 108513..109511 | + | 999 | WP_002301165.1 | signal recognition particle-docking protein FtsY | - |
| CO999_RS00600 () | 109698..111965 | + | 2268 | WP_101701466.1 | bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB | - |
| CO999_RS00605 () | 112149..113102 | + | 954 | WP_002326066.1 | IS30 family transposase IS1252 | Transposase |
| CO999_RS00610 () | 113120..113572 | - | 453 | WP_002294287.1 | YueI family protein | - |
| CO999_RS00615 () | 113722..114672 | + | 951 | WP_002294286.1 | Ferric-anguibactin transport system permease protein FatD | VF |
| CO999_RS00620 () | 114665..115624 | + | 960 | WP_002301163.1 | Ferric-anguibactin transport system permease protein FatC | VF |
| CO999_RS00625 () | 115621..116376 | + | 756 | WP_002301162.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| CO999_RS00630 () | 116399..117352 | + | 954 | WP_002301160.1 | putative ABC transporter solute-binding protein YclQ | VF |
| CO999_RS00635 () | 117996..118292 | - | 297 | WP_002287909.1 | phenylalanyl-tRNA synthetase subunit alpha | - |
| CO999_RS00640 () | 118648..119004 | + | 357 | WP_002287910.1 | iron-sulfur cluster biosynthesis family protein | - |
| CO999_RS00645 () | 119014..119913 | + | 900 | WP_002348747.1 | metallophosphoesterase | - |
| CO999_RS00650 () | 120146..121105 | - | 960 | WP_010782507.1 | IS30 family transposase IS1062 | Transposase |
| CO999_RS00655 () | 121363..122808 | + | 1446 | WP_010782508.1 | IS1182 family transposase ISEfa7 | Transposase |
| CO999_RS00660 () | 122854..123588 | - | 735 | WP_002348590.1 | aquaporin family protein | - |
| CO999_RS00665 () | 123914..124324 | + | 411 | WP_002301190.1 | CidA/LrgA family protein | - |
| CO999_RS00670 () | 124317..125018 | + | 702 | WP_002294273.1 | LrgB family protein | - |
| CO999_RS00675 () | 125018..126631 | + | 1614 | WP_002348592.1 | helix-turn-helix domain-containing protein | - |
| CO999_RS00680 () | 126621..126842 | + | 222 | WP_002290506.1 | DUF2829 domain-containing protein | - |
| CO999_RS00685 () | 126839..127600 | + | 762 | WP_002297929.1 | 3-beta-hydroxycholanate 3-dehydrogenase (NAD(+)) 2 | VF |
| CO999_RS00690 () | 127981..128490 | + | 510 | WP_002294268.1 | QueT transporter family protein | - |
| CO999_RS00695 () | 128560..129099 | - | 540 | WP_002294267.1 | biotin transporter BioY | - |
| CO999_RS00700 () | 129239..129850 | - | 612 | WP_002294265.1 | 30S ribosomal protein S4 | - |
| CO999_RS00705 () | 130112..130963 | + | 852 | WP_002348593.1 | formate/nitrite transporter family protein | - |
| CO999_RS00710 () | 130991..131626 | + | 636 | WP_002294262.1 | DNA alkylation repair protein | - |
| CO999_RS00715 () | 131646..132419 | + | 774 | WP_002294261.1 | Cof-type HAD-IIB family hydrolase | - |
| CO999_RS00725 () | 132827..133624 | + | 798 | WP_002348595.1 | TIGR00282 family metallophosphoesterase | - |
| CO999_RS00730 () | 133602..134015 | + | 414 | WP_002297923.1 | YlbF family regulator | - |
| CO999_RS00735 () | 133999..136644 | + | 2646 | WP_002294258.1 | DNA mismatch repair protein MutS | - |
| CO999_RS00740 () | 136662..138770 | + | 2109 | WP_002301736.1 | DNA mismatch repair endonuclease MutL | - |
| CO999_RS00745 () | 138792..139352 | + | 561 | WP_002348596.1 | septum formation inhibitor Maf | - |
| CO999_RS00750 () | 139491..140786 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| CO999_RS00755 () | 141046..141240 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| CO999_RS00760 () | 141230..141583 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| CO999_RS00765 () | 141685..143232 | + | 1548 | WP_002296127.1 | IS66 family transposase ISRob1 | Transposase |
| CO999_RS00770 () | 143312..145300 | - | 1989 | WP_002348864.1 | PTS system trehalose-specific EIIBC component | - |
| CO999_RS00775 () | 145523..146236 | + | 714 | WP_002294254.1 | trehalose operon repressor | - |
| CO999_RS00780 () | 146313..146759 | + | 447 | WP_002294252.1 | Peptide methionine sulfoxide reductase MsrB | VF |
| CO999_RS00785 () | 146929..147531 | + | 603 | WP_002290528.1 | Holliday junction branch migration protein RuvA | - |
| CO999_RS00790 () | 147544..148545 | + | 1002 | WP_002289812.1 | Holliday junction ATP-dependent DNA helicase RuvB | VF |
| CO999_RS00795 () | 148574..149152 | + | 579 | WP_002341570.1 | TetR/AcrR family transcriptional regulator | - |
| CO999_RS00800 () | 149204..149686 | + | 483 | WP_002294249.1 | Low molecular weight protein-tyrosine-phosphatase YfkJ | VF |
| CO999_RS00805 () | 149803..150177 | + | 375 | WP_002289815.1 | hypothetical protein | - |
| CO999_RS00810 () | 150977..152329 | - | 1353 | WP_002294246.1 | branched-chain amino acid transport system II carrier protein | - |
| CO999_RS00815 () | 152476..153066 | + | 591 | WP_002297079.1 | DUF1211 domain-containing protein | - |
| CO999_RS00820 () | 153194..154543 | - | 1350 | WP_002294242.1 | amino acid permease | - |
| CO999_RS00825 () | 154711..155451 | - | 741 | WP_002294240.1 | Arginine transport ATP-binding protein ArtM | VF |
| CO999_RS00830 () | 155464..157056 | - | 1593 | WP_002297081.1 | ABC transporter permease subunit | - |
| CO999_RS00840 () | 157624..157920 | - | 297 | WP_002293448.1 | hypothetical protein | - |
| CO999_RS00845 () | 158096..158821 | + | 726 | WP_002294236.1 | NAD-dependent protein deacylase | - |
| CO999_RS00850 () | 158814..159656 | + | 843 | WP_002301156.1 | Maltose O-acetyltransferase | VF |
| CO999_RS00855 () | 159659..160180 | + | 522 | WP_002294232.1 | transcription repressor NadR | - |
| CO999_RS00865 () | 160433..160996 | - | 564 | WP_002289284.1 | peptide deformylase | - |
| CO999_RS00870 () | 161247..161516 | + | 270 | WP_002289282.1 | 30S ribosomal protein S15 | - |
| CO999_RS00875 () | 161704..163830 | + | 2127 | WP_002297086.1 | polyribonucleotide nucleotidyltransferase | - |
| CO999_RS00885 () | 164340..164606 | + | 267 | WP_002289280.1 | GlsB/YeaQ/YmgE family stress response membrane protein | - |
| CO999_RS00890 () | 164783..166741 | + | 1959 | WP_002321207.1 | KUP/HAK/KT family potassium transporter | - |
| CO999_RS00895 () | 167095..168396 | + | 1302 | WP_002294228.1 | hemolysin family protein | - |
| CO999_RS00900 () | 168772..170067 | - | 1296 | WP_002326809.1 | ISL3 family transposase ISEfa5 | Transposase |
| CO999_RS00905 () | 170204..171313 | - | 1110 | Protein_168 | IS110 family transposase ISSsu7 | Transposase |
| CO999_RS00915 () | 171660..173030 | - | 1371 | WP_002289277.1 | MATE family efflux transporter | - |
| CO999_RS00920 () | 173212..173535 | - | 324 | WP_002289744.1 | DUF960 domain-containing protein | - |
| CO999_RS00925 () | 173860..174468 | - | 609 | WP_002299254.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| CO999_RS00930 () | 174798..175514 | + | 717 | WP_002348768.1 | pseudouridine synthase | - |
| CO999_RS00935 () | 175527..176222 | + | 696 | WP_002289749.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| CO999_RS00940 () | 176306..176935 | + | 630 | WP_002289751.1 | uridine kinase | - |
| CO999_RS00950 () | 177450..178789 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| CO999_RS00955 () | 178858..179460 | + | 603 | WP_002294220.1 | TVP38/TMEM64 family protein | - |
| CO999_RS00960 () | 179482..179970 | + | 489 | WP_002296548.1 | GNAT family N-acetyltransferase | - |
| CO999_RS00965 () | 180291..181664 | + | 1374 | WP_002294217.1 | hypothetical protein | - |
| CO999_RS00970 () | 181648..182115 | + | 468 | WP_002294214.1 | YaiI/YqxD family protein | - |
| CO999_RS00975 () | 182364..184109 | - | 1746 | WP_002329999.1 | AarF/ABC1/UbiB kinase family protein | - |
| CO999_RS00980 () | 184305..185381 | + | 1077 | WP_002293424.1 | D-alanine--D-alanine ligase | - |
| CO999_RS00985 () | 185534..186886 | + | 1353 | WP_002317074.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| CO999_RS00990 () | 187208..188719 | + | 1512 | WP_002294211.1 | DEAD/DEAH box helicase | - |
| CO999_RS00995 () | 188849..189199 | + | 351 | WP_002294209.1 | holo-ACP synthase | - |
| CO999_RS01000 () | 189215..190336 | + | 1122 | WP_002294207.1 | alanine racemase | - |
| CO999_RS01005 () | 190347..190709 | + | 363 | WP_002289874.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| CO999_RS01015 () | 190885..191154 | - | 270 | WP_002293413.1 | 30S ribosomal protein S14 | - |
| CO999_RS01020 () | 191344..192291 | + | 948 | WP_002294206.1 | NADP-dependent oxidoreductase | - |
| CO999_RS01025 () | 192437..193732 | - | 1296 | WP_016171130.1 | ISL3 family transposase ISEfa5 | Transposase |
| CO999_RS01035 () | 193999..194958 | + | 960 | WP_002301399.1 | IS30 family transposase IS1062 | Transposase |
| CO999_RS01040 () | 195184..197889 | + | 2706 | WP_002294203.1 | YhgE/Pip domain-containing protein | - |
| CO999_RS01050 () | 198486..200309 | + | 1824 | WP_002294202.1 | APC family permease | - |
| CO999_RS01055 () | 200451..200636 | - | 186 | WP_002348885.1 | hypothetical protein | - |
| CO999_RS01065 () | 201111..201374 | + | 264 | WP_002294199.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| CO999_RS01070 () | 201374..201640 | + | 267 | WP_002301121.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| CO999_RS16055 () | 201841..202675 | + | 835 | Protein_196 | hypothetical protein | - |
| CO999_RS01080 () | 202871..203542 | - | 672 | WP_002301116.1 | ABC transporter permease | - |
| CO999_RS01085 () | 203539..204456 | - | 918 | WP_002301114.1 | osmoprotectant ABC transporter substrate-binding protein | - |
| CO999_RS01090 () | 204453..205094 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
| CO999_RS01095 () | 205098..206273 | - | 1176 | WP_002348889.1 | Carnitine transport ATP-binding protein OpuCA | VF |
| CO999_RS01100 () | 206466..207497 | + | 1032 | WP_002350806.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| CO999_RS01105 () | 207691..208984 | + | 1294 | Protein_202 | ISL3 family transposase IS1251 | Transposase |
| CO999_RS01110 () | 209174..210127 | + | 954 | WP_002341590.1 | IS30 family transposase IS1252 | Transposase |
| CO999_RS01115 () | 210218..211513 | + | 1296 | WP_002319878.1 | ISL3 family transposase IS1251 | Transposase |
| CO999_RS01120 () | 211675..212970 | + | 1296 | WP_002326809.1 | ISL3 family transposase ISEfa5 | Transposase |
| CO999_RS01125 () | 213680..216319 | + | 2640 | WP_002289743.1 | cation-translocating P-type ATPase | - |
| CO999_RS01130 () | 216487..217185 | - | 699 | WP_002294185.1 | DUF975 family protein | - |
| CO999_RS01135 () | 217288..218241 | - | 954 | WP_002341590.1 | IS30 family transposase IS1252 | Transposase |
| CO999_RS01140 () | 218470..219615 | + | 1146 | WP_002294183.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| CO999_RS01145 () | 219712..220092 | + | 381 | WP_002300794.1 | preprotein translocase subunit YajC | - |
| CO999_RS01155 () | 220397..222994 | + | 2598 | WP_010782512.1 | Aldehyde-alcohol dehydrogenase | VF |
| CO999_RS01160 () | 222902..224512 | - | 1611 | WP_010782513.1 | IS1182 family transposase ISEfa7 | Transposase |
| CO999_RS01165 () | 224789..225743 | + | 955 | Protein_213 | glycoside hydrolase family 88 protein | - |
| CO999_RS01170 () | 225760..226784 | + | 1025 | Protein_214 | TRAP transporter substrate-binding protein | - |
| CO999_RS01175 () | 226790..227269 | + | 480 | WP_002300788.1 | TRAP transporter small permease | - |
| CO999_RS01180 () | 227285..227863 | + | 579 | WP_002300787.1 | TRAP transporter large permease subunit | - |
| CO999_RS01185 () | 227895..229234 | + | 1340 | WP_086953915.1 | IS3-like element ISEnfa3 family transposase | - |
| CO999_RS01190 () | 229278..229484 | + | 207 | WP_126145175.1 | TRAP transporter large permease subunit | - |
| CO999_RS01195 () | 229466..229771 | + | 306 | WP_002300046.1 | 5-dehydro-4-deoxy-D-glucuronate isomerase | - |
| CO999_RS01200 () | 229791..230594 | + | 804 | WP_033582433.1 | gluconate 5-dehydrogenase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|