NZ_CP0237951..202553

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 202553 bp
Accession: NZ_CP023795        Location: 1..202553         Organism: Enterococcus faecium strain Efaecium_ER04484.3A       Replicon: plasmid pER04484.3A.1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO996_RS14805 () 1..1041 + 1041 WP_002303636.1 replication initiator protein A -
CO996_RS14810 () 1865..2197 + 333 WP_002323647.1 hypothetical protein -
CO996_RS14815 () 2816..3157 + 342 WP_002295674.1 DUF5406 domain-containing protein -
CO996_RS14820 () 3394..4644 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CO996_RS14825 () 5054..7426 + 2373 WP_002305801.1 hypothetical protein -
CO996_RS14830 () 7487..8947 + 1461 WP_002347152.1 toprim domain-containing protein -
CO996_RS14835 () 8958..11162 + 2205 WP_002305772.1 type IA DNA topoisomerase -
CO996_RS16490 () 11178..11327 + 150 WP_002303309.1 hypothetical protein -
CO996_RS14840 () 11403..11996 + 594 WP_002303311.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CO996_RS14845 () 12009..12908 + 900 WP_002303312.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO996_RS14850 () 12911..13384 + 474 WP_002321302.1 single-stranded DNA-binding protein -
CO996_RS14855 () 13750..14010 + 261 WP_002321303.1 hypothetical protein -
CO996_RS14860 () 14455..14661 + 207 WP_002296239.1 hypothetical protein -
CO996_RS14865 () 14661..14912 + 252 WP_002305766.1 hypothetical protein -
CO996_RS14870 () 14928..15344 + 417 WP_002305764.1 hypothetical protein -
CO996_RS14875 () 15326..15598 + 273 WP_002348912.1 hypothetical protein -
CO996_RS14880 () 15765..16166 + 402 WP_002305759.1 IS200-IS605 family transposase ISCpe2 Transposase
CO996_RS14885 () 16178..17323 + 1146 WP_002305757.1 IS200-IS605 family transposase ISEfa4 Transposase
CO996_RS14890 () 17561..17824 + 264 WP_002287514.1 hypothetical protein Antitoxin Detail
CO996_RS14895 () 17818..18168 + 351 WP_002321032.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
CO996_RS14900 () 18192..18806 - 615 WP_002318230.1 Tn3 family transposase TnpR_TnAs2 Transposase
CO996_RS14905 () 19256..20581 + 1326 WP_002348911.1 Y-family DNA polymerase -
CO996_RS14910 () 20574..20924 + 351 WP_002303114.1 hypothetical protein -
CO996_RS14915 () 20921..21100 + 180 WP_002322386.1 hypothetical protein -
CO996_RS14920 () 21112..21405 + 294 WP_002322251.1 hypothetical protein -
CO996_RS14925 () 21631..22449 + 819 WP_002305212.1 ParA family protein -
CO996_RS14930 () 22468..22875 + 408 WP_002305774.1 hypothetical protein -
CO996_RS14935 () 23195..24280 + 1086 WP_002322387.1 replication initiator protein A -
CO996_RS14940 () 25117..25449 + 333 WP_002310954.1 hypothetical protein -
CO996_RS14945 () 26040..26369 + 330 WP_002296227.1 hypothetical protein -
CO996_RS14950 () 26356..26697 + 342 WP_010782601.1 DUF5406 domain-containing protein -
CO996_RS14955 () 26811..27050 + 240 WP_002299885.1 hypothetical protein -
CO996_RS14960 () 27117..27356 + 240 WP_002299886.1 hypothetical protein -
CO996_RS14965 () 27483..28172 + 690 WP_002299887.1 sortase -
CO996_RS14970 () 28178..29344 + 1167 WP_002299888.1 EpaQ family protein -
CO996_RS14975 () 29426..30097 + 672 WP_002302875.1 class A sortase -
CO996_RS14980 () 30150..32126 + 1977 WP_002302873.1 isopeptide-forming domain-containing fimbrial protein -
CO996_RS14985 () 32139..32891 + 753 WP_002302871.1 hypothetical protein VF
CO996_RS14990 () 32907..33668 + 762 WP_002302869.1 hypothetical protein -
CO996_RS14995 () 33681..33941 + 261 WP_002302867.1 hypothetical protein -
CO996_RS15000 () 33938..36028 + 2091 WP_002305780.1 isopeptide-forming domain-containing fimbrial protein -
CO996_RS15005 () 36064..38121 - 2058 WP_002300034.1 Beta-L-arabinobiosidase VF
CO996_RS15010 () 38266..38457 - 192 WP_002300033.1 hypothetical protein -
CO996_RS15015 () 38645..39100 + 456 WP_002300032.1 hypothetical protein -
CO996_RS15020 () 39097..39339 + 243 WP_002305782.1 DUF5415 family protein -
CO996_RS15025 () 39357..39659 + 303 WP_002302862.1 hypothetical protein -
CO996_RS15030 () 39728..41782 + 2055 WP_002302860.1 hypothetical protein -
CO996_RS15035 () 41782..44394 + 2613 WP_002302859.1 type IV secretory system conjugative DNA transfer family protein -
CO996_RS15040 () 44391..46769 + 2379 WP_002302858.1 hypothetical protein -
CO996_RS15045 () 46830..47372 + 543 WP_002302857.1 hypothetical protein -
CO996_RS15050 () 47450..47782 + 333 WP_002302856.1 hypothetical protein -
CO996_RS15055 () 47783..48376 + 594 WP_002302855.1 hypothetical protein -
CO996_RS15060 () 48398..50422 + 2025 WP_002302854.1 hypothetical protein -
CO996_RS15065 () 50422..51621 + 1200 WP_002302853.1 glucosaminidase domain-containing protein -
CO996_RS15070 () 51637..52281 + 645 WP_002302852.1 hypothetical protein -
CO996_RS15075 () 52292..53098 + 807 WP_002302851.1 hypothetical protein -
CO996_RS15080 () 53121..53350 + 230 Protein_56 hypothetical protein -
CO996_RS15085 () 53371..54444 + 1074 WP_002296375.1 DUF4199 domain-containing protein -
CO996_RS15090 () 54488..54757 + 270 WP_002305788.1 hypothetical protein -
CO996_RS15095 () 55033..55308 + 276 WP_002302849.1 hypothetical protein -
CO996_RS15100 () 55350..55772 + 423 WP_002302844.1 hypothetical protein -
CO996_RS15105 () 55792..57384 + 1593 WP_033582318.1 hypothetical protein Relaxase
CO996_RS15110 () 57405..57740 + 336 WP_002302842.1 hypothetical protein -
CO996_RS15115 () 57886..58080 + 195 WP_002302840.1 hypothetical protein -
CO996_RS15120 () 58216..59466 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CO996_RS15125 () 59876..62248 + 2373 WP_002305801.1 hypothetical protein -
CO996_RS15130 () 62323..63777 + 1455 WP_087121894.1 toprim domain-containing protein -
CO996_RS15135 () 63788..65797 + 2010 WP_002303486.1 DNA topoisomerase III -
CO996_RS16495 () 65913..66062 + 150 WP_002295632.1 hypothetical protein -
CO996_RS15145 () 66143..66739 + 597 WP_002303484.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CO996_RS15150 () 66752..67651 + 900 WP_002303483.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO996_RS15155 () 67654..67785 + 132 WP_002301801.1 single-stranded DNA-binding protein -
CO996_RS15160 () 67807..68139 + 333 WP_002305808.1 single-stranded DNA-binding protein -
CO996_RS15165 () 68184..68417 + 234 WP_002303482.1 hypothetical protein -
CO996_RS15170 () 68576..68698 - 123 WP_002295624.1 putative holin-like toxin -
CO996_RS15175 () 68888..69112 + 225 WP_002305809.1 hypothetical protein -
CO996_RS15185 () 69555..69761 + 207 WP_002305810.1 hypothetical protein -
CO996_RS15190 () 69761..70012 + 252 WP_002300797.1 hypothetical protein -
CO996_RS16500 () 70028..70183 + 156 WP_002300799.1 hypothetical protein -
CO996_RS15195 () 70193..70465 + 273 WP_002300801.1 hypothetical protein -
CO996_RS15205 () 70910..71089 + 180 WP_002300804.1 hypothetical protein -
CO996_RS15210 () 71148..71504 + 357 WP_002311569.1 hypothetical protein -
CO996_RS15215 () 71692..72870 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO996_RS15220 () 73819..74772 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CO996_RS15225 () 74893..75156 + 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
CO996_RS15235 () 75528..76706 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO996_RS15240 () 77238..78146 + 909 WP_002332708.1 IS982 family transposase ISEfm1 Transposase
CO996_RS15245 () 78166..80088 + 1923 Protein_87 PTS sugar transporter subunit IIA -
CO996_RS15250 () 80091..80546 + 456 WP_002300835.1 PTS sugar transporter subunit IIA -
CO996_RS15255 () 80560..81888 + 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
CO996_RS15260 () 81922..82206 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
CO996_RS15265 () 82208..82723 + 516 WP_002300840.1 YjbQ family protein -
CO996_RS15270 () 82739..83401 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
CO996_RS15275 () 83408..83980 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
CO996_RS15280 () 84152..85699 - 1548 WP_002303202.1 IS66 family transposase ISRob1 Transposase
CO996_RS15285 () 85801..86154 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CO996_RS15290 () 86144..86338 - 195 WP_002285758.1 hypothetical protein -
CO996_RS15295 () 86520..88040 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
CO996_RS15305 () 88283..88468 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
CO996_RS15310 () 88452..88634 - 183 WP_002300846.1 hypothetical protein -
CO996_RS15315 () 88875..89093 + 219 Protein_100 IS256 family transposase ISLgar5 Transposase
CO996_RS15320 () 89588..90187 + 600 WP_002301839.1 Tyrosine recombinase XerD VF
CO996_RS15325 () 90251..90850 + 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
CO996_RS15330 () 90880..91531 - 652 Protein_103 IS6 family transposase IS1216V Transposase
CO996_RS15335 () 91866..92738 - 873 WP_002305879.1 ROK family protein -
CO996_RS15340 () 92981..94153 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
CO996_RS15345 () 94334..96280 - 1947 WP_002303302.1 sucrose-specific PTS transporter subunit IIBC -
CO996_RS15350 () 96465..97904 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
CO996_RS15355 () 97906..98868 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
CO996_RS15365 () 100707..101162 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
CO996_RS15375 () 101427..101525 + 99 Protein_111 IS30 family transposase -
CO996_RS15385 () 102208..103026 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
CO996_RS15390 () 103187..103876 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
CO996_RS15395 () 103890..105392 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
CO996_RS15400 () 105405..105881 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
CO996_RS16340 () 105978..106088 - 111 Protein_116 transposase -
CO996_RS15420 () 108659..109177 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
CO996_RS15435 () 111253..112338 + 1086 WP_002301591.1 tyrosine recombinase XerS -
CO996_RS15440 () 112446..113399 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CO996_RS15445 () 113530..114351 - 822 Protein_121 PTS sugar transporter subunit IIC -
CO996_RS15450 () 114481..115800 + 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
CO996_RS15455 () 116006..116464 - 459 Protein_123 PTS sugar transporter subunit IIC -
CO996_RS15460 () 116483..116968 - 486 Protein_124 haloacid dehalogenase-like hydrolase -
CO996_RS15465 () 117063..118241 + 1179 WP_002324322.1 IS256 family transposase ISEfm2 Transposase
CO996_RS15470 () 118269..118742 - 474 Protein_126 haloacid dehalogenase-like hydrolase -
CO996_RS15475 () 118821..119816 - 996 WP_002301128.1 tagatose-bisphosphate aldolase -
CO996_RS15480 () 119832..121001 - 1170 WP_002301130.1 SIS domain-containing protein -
CO996_RS15485 () 121017..121751 - 735 WP_002301131.1 GntR family transcriptional regulator -
CO996_RS15495 () 124253..125545 - 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
CO996_RS15500 () 125819..126079 - 261 WP_002313174.1 hypothetical protein -
CO996_RS15505 () 126330..127508 + 1179 WP_002346943.1 IS256 family transposase ISEf1 Transposase
CO996_RS15510 () 127860..128156 + 297 WP_073120200.1 IS3 family transposase ISEfa8 Transposase
CO996_RS15515 () 128079..128903 - 825 Protein_135 transposase -
CO996_RS15520 () 129105..129500 - 396 WP_002287876.1 aspartate 1-decarboxylase -
CO996_RS15525 () 129510..130358 - 849 WP_002287875.1 pantoate--beta-alanine ligase -
CO996_RS15530 () 130373..131200 - 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
CO996_RS15535 () 131212..132072 - 861 Protein_139 DUF2520 domain-containing protein -
CO996_RS15540 () 132271..132465 + 195 WP_002285758.1 hypothetical protein -
CO996_RS15545 () 132455..132808 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CO996_RS15550 () 132910..134457 + 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
CO996_RS15555 () 134663..135832 + 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
CO996_RS15560 () 136172..136852 - 681 WP_010782692.1 IS6 family transposase IS1216E Transposase
CO996_RS15565 () 137482..138654 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
CO996_RS15570 () 138905..140224 + 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
CO996_RS15575 () 140468..141208 - 741 Protein_147 APH(2'')-Ia/If/Ih family aminoglycoside O-phosphotransferase -
CO996_RS15580 () 141316..142494 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO996_RS15585 () 142461..143124 - 664 Protein_149 GNAT family N-acetyltransferase -
CO996_RS15590 () 143179..143355 - 177 Protein_150 IS6 family transposase IS1216V Transposase
CO996_RS15595 () 143515..145062 - 1548 WP_158294579.1 IS3 family transposase ISPa31 Transposase
CO996_RS15600 () 145132..145386 - 255 Protein_152 replication initiation protein -
CO996_RS15605 () 146062..146613 - 552 WP_002303113.1 DUF334 domain-containing protein -
CO996_RS15610 () 146708..147088 - 381 Protein_154 IS6 family transposase IS1216V Transposase
CO996_RS15620 () 147158..147838 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
CO996_RS15625 () 147866..148429 + 564 WP_002304893.1 Tn3 family transposase TnpR_ISPa40 Transposase
CO996_RS15630 () 148474..148641 - 168 WP_000824191.1 hypothetical protein -
CO996_RS15635 () 148675..148974 - 300 WP_000366408.1 BRCT domain-containing protein -
CO996_RS15640 () 149015..149632 - 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
CO996_RS15645 () 149957..150352 - 396 WP_002304891.1 hypothetical protein -
CO996_RS15650 () 150432..152783 - 2352 WP_000344083.1 DUF1906 domain-containing protein -
CO996_RS15655 () 152908..153597 - 690 WP_000718009.1 hypothetical protein -
CO996_RS15660 () 153611..154063 - 453 WP_000751236.1 hypothetical protein -
CO996_RS15665 () 154194..154874 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CO996_RS15675 () 155493..155696 - 204 WP_002348841.1 hypothetical protein -
CO996_RS15685 () 156155..157120 - 966 WP_002305972.1 Replication initiation protein Relaxase
CO996_RS15690 () 157200..157880 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CO996_RS15695 () 157982..158863 - 882 Protein_168 HAMP domain-containing histidine kinase -
CO996_RS15700 () 158966..160138 + 1173 WP_002316137.1 IS256 family transposase IS256 Transposase
CO996_RS15705 () 160775..161184 - 410 Protein_170 IS200-IS605 family transposase ISAac1 Transposase
CO996_RS15715 () 161418..162281 - 864 WP_101701477.1 triphosphoribosyl-dephospho-CoA synthase CitG -
CO996_RS15720 () 162274..162831 - 558 WP_002305953.1 citrate lyase holo-[acyl-carrier protein] synthase -
CO996_RS15725 () 162828..164387 - 1560 WP_002303161.1 citrate lyase subunit alpha -
CO996_RS15730 () 164380..165285 - 906 WP_002303160.1 citrate (pro-3S)-lyase subunit beta -
CO996_RS15735 () 165290..165583 - 294 WP_002303159.1 citrate lyase acyl carrier protein -
CO996_RS15740 () 165587..166600 - 1014 WP_002303158.1 [citrate (pro-3S)-lyase] ligase -
CO996_RS15745 () 166626..167930 - 1305 WP_002303157.1 2-hydroxycarboxylate transporter family protein -
CO996_RS15750 () 167911..169098 - 1188 WP_002303156.1 NADP-dependent malic enzyme -
CO996_RS15755 () 169287..170234 + 948 WP_002303155.1 DNA-binding transcriptional regulator -
CO996_RS15760 () 170531..171079 - 549 WP_002292681.1 hypothetical protein -
CO996_RS15765 () 171080..171937 - 858 WP_002292680.1 AAA family ATPase -
CO996_RS15770 () 172223..172510 - 288 WP_002313074.1 type II toxin-antitoxin system RelE/ParE family toxin -
CO996_RS15775 () 172500..172829 - 330 WP_002292678.1 AbrB family transcriptional regulator -
CO996_RS15780 () 172978..173658 - 681 Protein_184 IS6 family transposase IS1216V Transposase
CO996_RS15785 () 173732..174013 - 282 Protein_185 YfbU family protein -
CO996_RS15790 () 174475..175857 + 1383 Protein_186 IS3 family transposase ISLca1 Transposase
CO996_RS15795 () 176093..176965 - 873 WP_016171159.1 ROK family protein -
CO996_RS15800 () 176982..178454 - 1473 WP_002322556.1 glycoside hydrolase family 32 protein -
CO996_RS15805 () 178468..179316 - 849 WP_002313079.1 carbohydrate ABC transporter permease -
CO996_RS15810 () 179313..180179 - 867 WP_002348858.1 sugar ABC transporter permease -
CO996_RS15815 () 180222..181535 - 1314 WP_016171161.1 sugar ABC transporter substrate-binding protein -
CO996_RS15820 () 181675..182646 - 972 WP_016171162.1 LacI family DNA-binding transcriptional regulator -
CO996_RS15825 () 182772..182999 - 228 Protein_193 IS110 family transposase -
CO996_RS15830 () 183164..183499 - 336 Protein_194 Tn3 family transposase TnpA_ISXc4 Transposase
CO996_RS15835 () 183681..184286 + 606 WP_002313084.1 Tn3 family transposase TnpR_ISPa40 Transposase
CO996_RS15840 () 184332..184511 - 180 WP_002340501.1 IS21 family transposase ISAar36 Transposase
CO996_RS15845 () 184998..185198 - 201 Protein_197 hypothetical protein -
CO996_RS16345 () 185737..186008 - 272 Protein_198 HAD-IA family hydrolase -
CO996_RS15855 () 186119..187027 + 909 WP_016171164.1 IS982 family transposase ISEfm1 Transposase
CO996_RS15860 () 187086..188888 - 1803 WP_002342383.1 3'-5' exoribonuclease -
CO996_RS15865 () 188951..189793 - 843 WP_002342384.1 hypothetical protein -
CO996_RS15870 () 189809..190030 - 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
CO996_RS15875 () 190173..190451 - 279 Protein_203 site-specific recombinase -
CO996_RS15880 () 190526..191206 + 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
CO996_RS15885 () 191264..192484 - 1221 WP_002339142.1 PAS domain-containing protein -
CO996_RS15890 () 192504..193115 - 612 WP_002339141.1 NAD(P)H-dependent oxidoreductase -
CO996_RS15895 () 193158..194090 - 933 WP_002339140.1 FAD:protein FMN transferase -
CO996_RS15900 () 194515..195372 - 858 WP_002339139.1 helix-turn-helix domain-containing protein -
CO996_RS15905 () 195519..196199 - 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
CO996_RS15910 () 196312..196500 - 189 WP_002296843.1 hypothetical protein -
CO996_RS15915 () 196645..197325 - 681 WP_010782695.1 IS6 family transposase IS1216V Transposase
CO996_RS15920 () 197801..198118 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
CO996_RS15925 () 198119..198373 - 255 WP_002303208.1 hypothetical protein -
CO996_RS15930 () 198732..199136 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
CO996_RS15935 () 199153..200301 + 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
CO996_RS15940 () 200524..200742 - 219 Protein_216 type II toxin-antitoxin system RelE/ParE family toxin -
CO996_RS15945 () 201008..201202 - 195 WP_002348857.1 hypothetical protein -
CO996_RS16505 () 201302..201388 - 87 Protein_218 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance