NZ_CP0237901..199068

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 199068 bp
Accession: NZ_CP023790        Location: 1..199068         Organism: Enterococcus faecium strain Efaecium_ER04462.3A       Replicon: plasmid pER04462.3A.1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO995_RS14800 () 1..1041 + 1041 WP_002303636.1 replication initiator protein A -
CO995_RS14805 () 1865..2197 + 333 WP_002323647.1 hypothetical protein -
CO995_RS14810 () 2816..3157 + 342 WP_002295674.1 DUF5406 domain-containing protein -
CO995_RS14815 () 3394..4644 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CO995_RS14820 () 5054..7426 + 2373 WP_002305801.1 hypothetical protein -
CO995_RS14825 () 7487..8947 + 1461 WP_002347152.1 toprim domain-containing protein -
CO995_RS14830 () 8958..11162 + 2205 WP_002305772.1 type IA DNA topoisomerase -
CO995_RS16465 () 11178..11327 + 150 WP_002303309.1 hypothetical protein -
CO995_RS14835 () 11403..11996 + 594 WP_002303311.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CO995_RS14840 () 12009..12908 + 900 WP_002303312.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO995_RS14845 () 12911..13384 + 474 WP_002321302.1 single-stranded DNA-binding protein -
CO995_RS14850 () 13750..14010 + 261 WP_002321303.1 hypothetical protein -
CO995_RS14855 () 14455..14661 + 207 WP_002296239.1 hypothetical protein -
CO995_RS14860 () 14661..14912 + 252 WP_002305766.1 hypothetical protein -
CO995_RS14865 () 14928..15344 + 417 WP_002305764.1 hypothetical protein -
CO995_RS14870 () 15326..15598 + 273 WP_002348912.1 hypothetical protein -
CO995_RS14875 () 15765..16166 + 402 WP_002305759.1 IS200-IS605 family transposase ISCpe2 Transposase
CO995_RS14880 () 16178..17323 + 1146 WP_002305757.1 IS200-IS605 family transposase ISEfa4 Transposase
CO995_RS14885 () 17561..17824 + 264 WP_002287514.1 hypothetical protein Antitoxin Detail
CO995_RS14890 () 17818..18168 + 351 WP_002321032.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
CO995_RS14895 () 18192..18806 - 615 WP_002318230.1 Tn3 family transposase TnpR_TnAs2 Transposase
CO995_RS14900 () 19256..20581 + 1326 WP_002348911.1 Y-family DNA polymerase -
CO995_RS14905 () 20574..20924 + 351 WP_002303114.1 hypothetical protein -
CO995_RS14910 () 20921..21100 + 180 WP_002322386.1 hypothetical protein -
CO995_RS14915 () 21112..21405 + 294 WP_002322251.1 hypothetical protein -
CO995_RS14920 () 21631..22449 + 819 WP_002305212.1 ParA family protein -
CO995_RS14925 () 22468..22875 + 408 WP_002305774.1 hypothetical protein -
CO995_RS14930 () 23195..24280 + 1086 WP_002322387.1 replication initiator protein A -
CO995_RS14935 () 25117..25449 + 333 WP_002310954.1 hypothetical protein -
CO995_RS14940 () 26040..26369 + 330 WP_002296227.1 hypothetical protein -
CO995_RS14945 () 26356..26697 + 342 WP_010782601.1 DUF5406 domain-containing protein -
CO995_RS14950 () 26811..27050 + 240 WP_002299885.1 hypothetical protein -
CO995_RS14955 () 27117..27356 + 240 WP_002299886.1 hypothetical protein -
CO995_RS14960 () 27483..28172 + 690 WP_002299887.1 sortase -
CO995_RS14965 () 28178..29344 + 1167 WP_002299888.1 EpaQ family protein -
CO995_RS14970 () 29426..30097 + 672 WP_002302875.1 class A sortase -
CO995_RS14975 () 30150..32126 + 1977 WP_002302873.1 isopeptide-forming domain-containing fimbrial protein -
CO995_RS14980 () 32139..32891 + 753 WP_002302871.1 hypothetical protein VF
CO995_RS14985 () 32907..33668 + 762 WP_002302869.1 hypothetical protein -
CO995_RS14990 () 33681..33941 + 261 WP_002302867.1 hypothetical protein -
CO995_RS14995 () 33938..36028 + 2091 WP_002305780.1 isopeptide-forming domain-containing fimbrial protein -
CO995_RS15000 () 36064..38121 - 2058 WP_002300034.1 Beta-L-arabinobiosidase VF
CO995_RS15005 () 38266..38457 - 192 WP_002300033.1 hypothetical protein -
CO995_RS15010 () 38645..39100 + 456 WP_002300032.1 hypothetical protein -
CO995_RS15015 () 39097..39339 + 243 WP_002305782.1 DUF5415 family protein -
CO995_RS15020 () 39357..39659 + 303 WP_002302862.1 hypothetical protein -
CO995_RS15025 () 39728..41782 + 2055 WP_002302860.1 hypothetical protein -
CO995_RS15030 () 41782..44394 + 2613 WP_002302859.1 type IV secretory system conjugative DNA transfer family protein -
CO995_RS15035 () 44391..46769 + 2379 WP_002302858.1 hypothetical protein -
CO995_RS15040 () 46830..47372 + 543 WP_002302857.1 hypothetical protein -
CO995_RS15045 () 47450..47782 + 333 WP_002302856.1 hypothetical protein -
CO995_RS15050 () 47783..48376 + 594 WP_002302855.1 hypothetical protein -
CO995_RS15055 () 48398..50422 + 2025 WP_002302854.1 hypothetical protein -
CO995_RS15060 () 50422..51621 + 1200 WP_002302853.1 glucosaminidase domain-containing protein -
CO995_RS15065 () 51637..52281 + 645 WP_002302852.1 hypothetical protein -
CO995_RS15070 () 52292..53098 + 807 WP_002302851.1 hypothetical protein -
CO995_RS15075 () 53121..53350 + 230 Protein_56 hypothetical protein -
CO995_RS15080 () 53371..54444 + 1074 WP_002296375.1 DUF4199 domain-containing protein -
CO995_RS15085 () 54488..54757 + 270 WP_002305788.1 hypothetical protein -
CO995_RS15090 () 55033..55308 + 276 WP_002302849.1 hypothetical protein -
CO995_RS15095 () 55350..55772 + 423 WP_002302844.1 hypothetical protein -
CO995_RS15100 () 55792..57384 + 1593 WP_033582318.1 hypothetical protein Relaxase
CO995_RS15105 () 57405..57740 + 336 WP_002302842.1 hypothetical protein -
CO995_RS15110 () 57886..58080 + 195 WP_002302840.1 hypothetical protein -
CO995_RS15115 () 58216..59466 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
CO995_RS15120 () 59876..62248 + 2373 WP_002305801.1 hypothetical protein -
CO995_RS15125 () 62309..63778 + 1470 WP_002353594.1 toprim domain-containing protein -
CO995_RS15130 () 63789..65798 + 2010 WP_002303486.1 DNA topoisomerase III -
CO995_RS16470 () 65914..66063 + 150 WP_002295632.1 hypothetical protein -
CO995_RS15140 () 66144..66740 + 597 WP_002303484.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
CO995_RS15145 () 66753..67652 + 900 WP_002303483.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO995_RS15150 () 67655..67786 + 132 WP_002301801.1 single-stranded DNA-binding protein -
CO995_RS15155 () 67808..68140 + 333 WP_002305808.1 single-stranded DNA-binding protein -
CO995_RS15160 () 68185..68418 + 234 WP_002303482.1 hypothetical protein -
CO995_RS15165 () 68577..68699 - 123 WP_002295624.1 putative holin-like toxin -
CO995_RS15170 () 68889..69113 + 225 WP_002305809.1 hypothetical protein -
CO995_RS15180 () 69556..69762 + 207 WP_002305810.1 hypothetical protein -
CO995_RS15185 () 69762..70013 + 252 WP_002300797.1 hypothetical protein -
CO995_RS16475 () 70029..70184 + 156 WP_002300799.1 hypothetical protein -
CO995_RS15190 () 70194..70466 + 273 WP_002300801.1 hypothetical protein -
CO995_RS15200 () 70911..71090 + 180 WP_002300804.1 hypothetical protein -
CO995_RS15205 () 71149..71505 + 357 WP_002311569.1 hypothetical protein -
CO995_RS15215 () 72474..73427 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CO995_RS15220 () 73548..73811 + 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
CO995_RS15230 () 74183..75361 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO995_RS15235 () 75893..76801 + 909 WP_002332708.1 IS982 family transposase ISEfm1 Transposase
CO995_RS15240 () 76821..78743 + 1923 Protein_86 PTS sugar transporter subunit IIA -
CO995_RS15245 () 78746..79201 + 456 WP_002300835.1 PTS sugar transporter subunit IIA -
CO995_RS15250 () 79215..80543 + 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
CO995_RS15255 () 80577..80861 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
CO995_RS15260 () 80863..81378 + 516 WP_002300840.1 YjbQ family protein -
CO995_RS15265 () 81394..82056 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
CO995_RS15270 () 82063..82635 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
CO995_RS15275 () 82807..84354 - 1548 WP_002303202.1 IS66 family transposase ISRob1 Transposase
CO995_RS15280 () 84456..84809 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CO995_RS15285 () 84799..84993 - 195 WP_002285758.1 hypothetical protein -
CO995_RS15290 () 85175..86695 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
CO995_RS15300 () 86938..87123 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
CO995_RS15305 () 87107..87289 - 183 WP_002300846.1 hypothetical protein -
CO995_RS15310 () 87530..87748 + 219 Protein_99 IS256 family transposase ISLgar5 Transposase
CO995_RS15315 () 88243..88842 + 600 WP_002301839.1 Tyrosine recombinase XerD VF
CO995_RS15320 () 88906..89505 + 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
CO995_RS15325 () 89535..90186 - 652 Protein_102 IS6 family transposase IS1216V Transposase
CO995_RS15330 () 90521..91393 - 873 WP_002305879.1 ROK family protein -
CO995_RS15335 () 91657..93603 - 1947 WP_002303302.1 sucrose-specific PTS transporter subunit IIBC -
CO995_RS15340 () 93788..95227 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
CO995_RS15345 () 95229..96191 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
CO995_RS15355 () 98030..98485 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
CO995_RS15365 () 98750..98848 + 99 Protein_109 IS30 family transposase -
CO995_RS15375 () 99531..100349 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
CO995_RS15380 () 100510..101199 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
CO995_RS15385 () 101213..102715 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
CO995_RS15390 () 102728..103204 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
CO995_RS16320 () 103301..103411 - 111 Protein_114 transposase -
CO995_RS15410 () 105982..106500 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
CO995_RS15425 () 108576..109661 + 1086 WP_002301591.1 tyrosine recombinase XerS -
CO995_RS15430 () 109769..110722 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
CO995_RS15435 () 110853..111674 - 822 Protein_119 PTS sugar transporter subunit IIC -
CO995_RS15440 () 111804..113123 + 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
CO995_RS15445 () 113329..113787 - 459 Protein_121 PTS sugar transporter subunit IIC -
CO995_RS15450 () 113806..114291 - 486 Protein_122 haloacid dehalogenase-like hydrolase -
CO995_RS15455 () 114386..115564 + 1179 WP_002324322.1 IS256 family transposase ISEfm2 Transposase
CO995_RS15460 () 115592..116065 - 474 Protein_124 haloacid dehalogenase-like hydrolase -
CO995_RS15465 () 116144..117139 - 996 WP_002301128.1 tagatose-bisphosphate aldolase -
CO995_RS15470 () 117155..118324 - 1170 WP_002301130.1 SIS domain-containing protein -
CO995_RS15475 () 118340..119074 - 735 WP_002301131.1 GntR family transcriptional regulator -
CO995_RS15485 () 121576..122868 - 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
CO995_RS15490 () 123142..123402 - 261 WP_002313174.1 hypothetical protein -
CO995_RS15495 () 123653..124831 + 1179 WP_002346943.1 IS256 family transposase ISEf1 Transposase
CO995_RS15500 () 125183..125479 + 297 WP_073120200.1 IS3 family transposase ISEfa8 Transposase
CO995_RS15505 () 125402..126226 - 825 Protein_133 transposase -
CO995_RS15510 () 126428..126823 - 396 WP_002287876.1 aspartate 1-decarboxylase -
CO995_RS15515 () 126833..127681 - 849 WP_002287875.1 pantoate--beta-alanine ligase -
CO995_RS15520 () 127696..128523 - 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
CO995_RS15525 () 128535..129395 - 861 Protein_137 DUF2520 domain-containing protein -
CO995_RS15530 () 129594..129788 + 195 WP_002285758.1 hypothetical protein -
CO995_RS15535 () 129778..130131 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
CO995_RS15540 () 130233..131780 + 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
CO995_RS15545 () 131986..133155 + 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
CO995_RS15550 () 133495..134175 - 681 WP_010782692.1 IS6 family transposase IS1216E Transposase
CO995_RS15555 () 134805..135977 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
CO995_RS15560 () 136228..137547 + 1320 WP_002348774.1 IS1380 family transposase IS1678 Transposase
CO995_RS15565 () 137791..138531 - 741 Protein_145 APH(2'')-Ia/If/Ih family aminoglycoside O-phosphotransferase -
CO995_RS15570 () 138639..139817 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
CO995_RS15575 () 139784..140447 - 664 Protein_147 GNAT family N-acetyltransferase -
CO995_RS15580 () 140502..140678 - 177 Protein_148 IS6 family transposase IS1216V Transposase
CO995_RS15585 () 140838..142385 - 1548 WP_158294579.1 IS3 family transposase ISPa31 Transposase
CO995_RS15590 () 142455..142709 - 255 Protein_150 replication initiation protein -
CO995_RS15595 () 143385..143936 - 552 WP_002303113.1 DUF334 domain-containing protein -
CO995_RS15600 () 144031..144411 - 381 Protein_152 IS6 family transposase IS1216V Transposase
CO995_RS15610 () 144481..145161 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
CO995_RS15615 () 145189..145752 + 564 WP_002304893.1 Tn3 family transposase TnpR_ISPa40 Transposase
CO995_RS15620 () 145797..145964 - 168 WP_000824191.1 hypothetical protein -
CO995_RS15625 () 145998..146297 - 300 WP_000366408.1 BRCT domain-containing protein -
CO995_RS15630 () 146338..146955 - 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
CO995_RS15635 () 147280..147675 - 396 WP_002304891.1 hypothetical protein -
CO995_RS15640 () 147755..150106 - 2352 WP_000344083.1 DUF1906 domain-containing protein -
CO995_RS15645 () 150231..150920 - 690 WP_000718009.1 hypothetical protein -
CO995_RS15650 () 150934..151386 - 453 WP_000751236.1 hypothetical protein -
CO995_RS15655 () 151517..152197 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CO995_RS15665 () 152670..153635 - 966 WP_002305972.1 Replication initiation protein Relaxase
CO995_RS15670 () 153715..154395 + 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
CO995_RS15675 () 154497..155378 - 882 Protein_165 HAMP domain-containing histidine kinase -
CO995_RS15680 () 155481..156653 + 1173 WP_002316137.1 IS256 family transposase IS256 Transposase
CO995_RS15685 () 157290..157699 - 410 Protein_167 IS200-IS605 family transposase ISAac1 Transposase
CO995_RS15695 () 157933..158796 - 864 WP_101701477.1 triphosphoribosyl-dephospho-CoA synthase CitG -
CO995_RS15700 () 158789..159346 - 558 WP_002305953.1 citrate lyase holo-[acyl-carrier protein] synthase -
CO995_RS15705 () 159343..160902 - 1560 WP_002303161.1 citrate lyase subunit alpha -
CO995_RS15710 () 160895..161800 - 906 WP_002303160.1 citrate (pro-3S)-lyase subunit beta -
CO995_RS15715 () 161805..162098 - 294 WP_002303159.1 citrate lyase acyl carrier protein -
CO995_RS15720 () 162102..163115 - 1014 WP_002303158.1 [citrate (pro-3S)-lyase] ligase -
CO995_RS15725 () 163141..164445 - 1305 WP_002303157.1 2-hydroxycarboxylate transporter family protein -
CO995_RS15730 () 164426..165613 - 1188 WP_002303156.1 NADP-dependent malic enzyme -
CO995_RS15735 () 165802..166749 + 948 WP_002303155.1 DNA-binding transcriptional regulator -
CO995_RS15740 () 167046..167594 - 549 WP_002292681.1 hypothetical protein -
CO995_RS15745 () 167595..168452 - 858 WP_002292680.1 AAA family ATPase -
CO995_RS15750 () 168738..169025 - 288 WP_002313074.1 type II toxin-antitoxin system RelE/ParE family toxin -
CO995_RS15755 () 169015..169344 - 330 WP_002292678.1 AbrB family transcriptional regulator -
CO995_RS15760 () 169493..170173 - 681 Protein_181 IS6 family transposase IS1216V Transposase
CO995_RS15765 () 170247..170528 - 282 Protein_182 YfbU family protein -
CO995_RS15770 () 170990..172372 + 1383 Protein_183 IS3 family transposase ISLca1 Transposase
CO995_RS15775 () 172608..173480 - 873 WP_016171159.1 ROK family protein -
CO995_RS15780 () 173497..174969 - 1473 WP_002322556.1 glycoside hydrolase family 32 protein -
CO995_RS15785 () 174983..175831 - 849 WP_002313079.1 carbohydrate ABC transporter permease -
CO995_RS15790 () 175828..176694 - 867 WP_002348858.1 sugar ABC transporter permease -
CO995_RS15795 () 176737..178050 - 1314 WP_016171161.1 sugar ABC transporter substrate-binding protein -
CO995_RS15800 () 178190..179161 - 972 WP_016171162.1 LacI family DNA-binding transcriptional regulator -
CO995_RS15805 () 179287..179514 - 228 Protein_190 IS110 family transposase -
CO995_RS15810 () 179679..180014 - 336 Protein_191 Tn3 family transposase TnpA_ISXc4 Transposase
CO995_RS15815 () 180196..180801 + 606 WP_002313084.1 Tn3 family transposase TnpR_ISPa40 Transposase
CO995_RS15820 () 180847..181026 - 180 WP_002340501.1 IS21 family transposase ISAar36 Transposase
CO995_RS15825 () 181513..181713 - 201 Protein_194 hypothetical protein -
CO995_RS16325 () 182252..182523 - 272 Protein_195 HAD-IA family hydrolase -
CO995_RS15835 () 182634..183542 + 909 WP_016171164.1 IS982 family transposase ISEfm1 Transposase
CO995_RS15840 () 183601..185403 - 1803 WP_002342383.1 3'-5' exoribonuclease -
CO995_RS15845 () 185466..186308 - 843 WP_002342384.1 hypothetical protein -
CO995_RS15850 () 186324..186545 - 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
CO995_RS15855 () 186688..186966 - 279 Protein_200 site-specific recombinase -
CO995_RS15860 () 187041..187721 + 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
CO995_RS15865 () 187779..188999 - 1221 WP_002339142.1 PAS domain-containing protein -
CO995_RS15870 () 189019..189630 - 612 WP_002339141.1 NAD(P)H-dependent oxidoreductase -
CO995_RS15875 () 189673..190605 - 933 WP_002339140.1 FAD:protein FMN transferase -
CO995_RS15880 () 191030..191887 - 858 WP_002339139.1 helix-turn-helix domain-containing protein -
CO995_RS15885 () 192034..192714 - 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
CO995_RS15890 () 192827..193015 - 189 WP_002296843.1 hypothetical protein -
CO995_RS15895 () 193160..193840 - 681 WP_010782695.1 IS6 family transposase IS1216V Transposase
CO995_RS15900 () 194316..194633 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
CO995_RS15905 () 194634..194888 - 255 WP_002303208.1 hypothetical protein -
CO995_RS15910 () 195247..195651 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
CO995_RS15915 () 195668..196816 + 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
CO995_RS15920 () 197039..197257 - 219 Protein_213 type II toxin-antitoxin system RelE/ParE family toxin -
CO995_RS15925 () 197523..197717 - 195 WP_002348857.1 hypothetical protein -
CO995_RS16480 () 197817..197903 - 87 Protein_215 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance