MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 129878 bp
Accession: NZ_CP023784 Location: 97372..227249 Organism: Enterococcus faecium strain Efaecium_ER04120.3A Replicon: chromosome
Accession: NZ_CP023784 Location: 97372..227249 Organism: Enterococcus faecium strain Efaecium_ER04120.3A Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CO994_RS00520 () | 92474..92662 | - | 189 | WP_002290463.1 | 50S ribosomal protein L28 | - |
| CO994_RS00530 () | 92932..93294 | + | 363 | WP_002294298.1 | Asp23/Gls24 family envelope stress response protein | - |
| CO994_RS00535 () | 93346..95028 | + | 1683 | WP_002301169.1 | DAK2 domain-containing protein | - |
| CO994_RS00540 () | 95145..97181 | + | 2037 | WP_002301167.1 | ATP-dependent DNA helicase RecG | - |
| CO994_RS00545 () | 97230..98231 | + | 1002 | WP_002289721.1 | phosphate acyltransferase PlsX | - |
| CO994_RS00550 () | 98353..98595 | + | 243 | WP_002294295.1 | Acyl carrier protein | VF |
| CO994_RS00555 () | 98863..99867 | + | 1005 | WP_002287889.1 | Oligopeptide transport ATP-binding protein OppD | VF |
| CO994_RS00560 () | 99868..100812 | + | 945 | WP_002287891.1 | Oligopeptide transport ATP-binding protein OppF | VF |
| CO994_RS00565 () | 100812..101774 | + | 963 | WP_002287892.1 | ABC transporter permease | - |
| CO994_RS00570 () | 101801..102715 | + | 915 | WP_002287893.1 | ABC transporter permease | - |
| CO994_RS00575 () | 102741..104522 | + | 1782 | WP_002287894.1 | oligopeptide ABC transporter substrate-binding protein | - |
| CO994_RS00585 () | 104870..105556 | + | 687 | WP_002287896.1 | ribonuclease III | - |
| CO994_RS00590 () | 105576..109157 | + | 3582 | WP_002301166.1 | chromosome segregation protein SMC | - |
| CO994_RS00595 () | 109166..109975 | + | 810 | WP_002348798.1 | Cof-type HAD-IIB family hydrolase | - |
| CO994_RS00600 () | 109987..110985 | + | 999 | WP_002301165.1 | signal recognition particle-docking protein FtsY | - |
| CO994_RS00605 () | 111172..113439 | + | 2268 | WP_101701466.1 | bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB | - |
| CO994_RS00610 () | 113623..114576 | + | 954 | WP_002326066.1 | IS30 family transposase IS1252 | Transposase |
| CO994_RS00615 () | 114594..115046 | - | 453 | WP_002294287.1 | YueI family protein | - |
| CO994_RS00620 () | 115196..116146 | + | 951 | WP_002294286.1 | Ferric-anguibactin transport system permease protein FatD | VF |
| CO994_RS00625 () | 116139..117098 | + | 960 | WP_002301163.1 | Ferric-anguibactin transport system permease protein FatC | VF |
| CO994_RS00630 () | 117095..117850 | + | 756 | WP_002301162.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| CO994_RS00635 () | 117873..118826 | + | 954 | WP_002301160.1 | putative ABC transporter solute-binding protein YclQ | VF |
| CO994_RS00640 () | 119470..119766 | - | 297 | WP_002287909.1 | phenylalanyl-tRNA synthetase subunit alpha | - |
| CO994_RS00645 () | 120122..120478 | + | 357 | WP_002287910.1 | iron-sulfur cluster biosynthesis family protein | - |
| CO994_RS00650 () | 120488..121387 | + | 900 | WP_002348747.1 | metallophosphoesterase | - |
| CO994_RS00655 () | 121620..122579 | - | 960 | WP_010782507.1 | IS30 family transposase IS1062 | Transposase |
| CO994_RS00660 () | 122837..124282 | + | 1446 | WP_010782508.1 | IS1182 family transposase ISEfa7 | Transposase |
| CO994_RS00665 () | 124328..125062 | - | 735 | WP_002348590.1 | aquaporin family protein | - |
| CO994_RS00670 () | 125388..125798 | + | 411 | WP_002301190.1 | CidA/LrgA family protein | - |
| CO994_RS00675 () | 125791..126492 | + | 702 | WP_002294273.1 | LrgB family protein | - |
| CO994_RS00680 () | 126492..128105 | + | 1614 | WP_002348592.1 | helix-turn-helix domain-containing protein | - |
| CO994_RS00685 () | 128095..128316 | + | 222 | WP_002290506.1 | DUF2829 domain-containing protein | - |
| CO994_RS00690 () | 128313..129074 | + | 762 | WP_002297929.1 | 3-beta-hydroxycholanate 3-dehydrogenase (NAD(+)) 2 | VF |
| CO994_RS00695 () | 129455..129964 | + | 510 | WP_002294268.1 | QueT transporter family protein | - |
| CO994_RS00700 () | 130034..130573 | - | 540 | WP_002294267.1 | biotin transporter BioY | - |
| CO994_RS00705 () | 130713..131324 | - | 612 | WP_002294265.1 | 30S ribosomal protein S4 | - |
| CO994_RS00710 () | 131586..132437 | + | 852 | WP_002348593.1 | formate/nitrite transporter family protein | - |
| CO994_RS00715 () | 132465..133100 | + | 636 | WP_002294262.1 | DNA alkylation repair protein | - |
| CO994_RS00720 () | 133120..133893 | + | 774 | WP_002294261.1 | Cof-type HAD-IIB family hydrolase | - |
| CO994_RS00730 () | 134301..135098 | + | 798 | WP_002348595.1 | TIGR00282 family metallophosphoesterase | - |
| CO994_RS00735 () | 135076..135489 | + | 414 | WP_002297923.1 | YlbF family regulator | - |
| CO994_RS00740 () | 135473..138118 | + | 2646 | WP_002294258.1 | DNA mismatch repair protein MutS | - |
| CO994_RS00745 () | 138136..140244 | + | 2109 | WP_002301736.1 | DNA mismatch repair endonuclease MutL | - |
| CO994_RS00750 () | 140266..140826 | + | 561 | WP_002348596.1 | septum formation inhibitor Maf | - |
| CO994_RS00755 () | 140965..142260 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| CO994_RS00760 () | 142520..142714 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| CO994_RS00765 () | 142704..143057 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| CO994_RS00770 () | 143159..144706 | + | 1548 | WP_002296127.1 | IS66 family transposase ISRob1 | Transposase |
| CO994_RS00775 () | 144786..146774 | - | 1989 | WP_002348864.1 | PTS system trehalose-specific EIIBC component | - |
| CO994_RS00780 () | 146997..147710 | + | 714 | WP_002294254.1 | trehalose operon repressor | - |
| CO994_RS00785 () | 147787..148233 | + | 447 | WP_002294252.1 | Peptide methionine sulfoxide reductase MsrB | VF |
| CO994_RS00790 () | 148403..149005 | + | 603 | WP_002290528.1 | Holliday junction branch migration protein RuvA | - |
| CO994_RS00795 () | 149018..150019 | + | 1002 | WP_002289812.1 | Holliday junction ATP-dependent DNA helicase RuvB | VF |
| CO994_RS00800 () | 150048..150626 | + | 579 | WP_002341570.1 | TetR/AcrR family transcriptional regulator | - |
| CO994_RS00805 () | 150678..151160 | + | 483 | WP_002294249.1 | Low molecular weight protein-tyrosine-phosphatase YfkJ | VF |
| CO994_RS00810 () | 151277..151651 | + | 375 | WP_002289815.1 | hypothetical protein | - |
| CO994_RS00815 () | 152451..153803 | - | 1353 | WP_002294246.1 | branched-chain amino acid transport system II carrier protein | - |
| CO994_RS00820 () | 153950..154540 | + | 591 | WP_002297079.1 | DUF1211 domain-containing protein | - |
| CO994_RS00825 () | 154668..156017 | - | 1350 | WP_002294242.1 | amino acid permease | - |
| CO994_RS00830 () | 156185..156925 | - | 741 | WP_002294240.1 | Arginine transport ATP-binding protein ArtM | VF |
| CO994_RS00835 () | 156938..158530 | - | 1593 | WP_002297081.1 | ABC transporter permease subunit | - |
| CO994_RS00845 () | 159098..159394 | - | 297 | WP_002293448.1 | hypothetical protein | - |
| CO994_RS00850 () | 159570..160295 | + | 726 | WP_002294236.1 | NAD-dependent protein deacylase | - |
| CO994_RS00855 () | 160288..161130 | + | 843 | WP_002301156.1 | Maltose O-acetyltransferase | VF |
| CO994_RS00860 () | 161133..161654 | + | 522 | WP_002294232.1 | transcription repressor NadR | - |
| CO994_RS00870 () | 161907..162470 | - | 564 | WP_002289284.1 | peptide deformylase | - |
| CO994_RS00875 () | 162721..162990 | + | 270 | WP_002289282.1 | 30S ribosomal protein S15 | - |
| CO994_RS00880 () | 163178..165304 | + | 2127 | WP_002297086.1 | polyribonucleotide nucleotidyltransferase | - |
| CO994_RS00890 () | 165814..166080 | + | 267 | WP_002289280.1 | GlsB/YeaQ/YmgE family stress response membrane protein | - |
| CO994_RS00895 () | 166257..168215 | + | 1959 | WP_002321207.1 | KUP/HAK/KT family potassium transporter | - |
| CO994_RS00900 () | 168569..169870 | + | 1302 | WP_002294228.1 | hemolysin family protein | - |
| CO994_RS00905 () | 170246..171541 | - | 1296 | WP_002326809.1 | ISL3 family transposase ISEfa5 | Transposase |
| CO994_RS00910 () | 171678..172787 | - | 1110 | Protein_169 | IS110 family transposase ISSsu7 | Transposase |
| CO994_RS00920 () | 173134..174504 | - | 1371 | WP_002289277.1 | MATE family efflux transporter | - |
| CO994_RS00925 () | 174686..175009 | - | 324 | WP_002289744.1 | DUF960 domain-containing protein | - |
| CO994_RS00930 () | 175334..175942 | - | 609 | WP_002299254.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| CO994_RS00935 () | 176272..176988 | + | 717 | WP_002348768.1 | pseudouridine synthase | - |
| CO994_RS00940 () | 177001..177696 | + | 696 | WP_002289749.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| CO994_RS00945 () | 177780..178409 | + | 630 | WP_002289751.1 | uridine kinase | - |
| CO994_RS00955 () | 178924..180263 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| CO994_RS00960 () | 180332..180934 | + | 603 | WP_002294220.1 | TVP38/TMEM64 family protein | - |
| CO994_RS00965 () | 180956..181444 | + | 489 | WP_002296548.1 | GNAT family N-acetyltransferase | - |
| CO994_RS00970 () | 181765..183138 | + | 1374 | WP_002294217.1 | hypothetical protein | - |
| CO994_RS00975 () | 183122..183589 | + | 468 | WP_002294214.1 | YaiI/YqxD family protein | - |
| CO994_RS00980 () | 183838..185583 | - | 1746 | WP_002329999.1 | AarF/ABC1/UbiB kinase family protein | - |
| CO994_RS00985 () | 185779..186855 | + | 1077 | WP_002293424.1 | D-alanine--D-alanine ligase | - |
| CO994_RS00990 () | 187008..188360 | + | 1353 | WP_002317074.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| CO994_RS00995 () | 188682..190193 | + | 1512 | WP_002294211.1 | DEAD/DEAH box helicase | - |
| CO994_RS01000 () | 190323..190673 | + | 351 | WP_002294209.1 | holo-ACP synthase | - |
| CO994_RS01005 () | 190689..191810 | + | 1122 | WP_002294207.1 | alanine racemase | - |
| CO994_RS01010 () | 191821..192183 | + | 363 | WP_002289874.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| CO994_RS01020 () | 192359..192628 | - | 270 | WP_002293413.1 | 30S ribosomal protein S14 | - |
| CO994_RS01025 () | 192818..193765 | + | 948 | WP_002294206.1 | NADP-dependent oxidoreductase | - |
| CO994_RS01030 () | 193911..195206 | - | 1296 | WP_016171130.1 | ISL3 family transposase ISEfa5 | Transposase |
| CO994_RS01040 () | 195473..196432 | + | 960 | WP_002301399.1 | IS30 family transposase IS1062 | Transposase |
| CO994_RS01045 () | 196658..199363 | + | 2706 | WP_002294203.1 | YhgE/Pip domain-containing protein | - |
| CO994_RS01055 () | 199960..201783 | + | 1824 | WP_002294202.1 | APC family permease | - |
| CO994_RS01060 () | 201925..202110 | - | 186 | WP_002348885.1 | hypothetical protein | - |
| CO994_RS01070 () | 202585..202848 | + | 264 | WP_002294199.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| CO994_RS01075 () | 202848..203114 | + | 267 | WP_002301121.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| CO994_RS16275 () | 203315..204149 | + | 835 | Protein_197 | hypothetical protein | - |
| CO994_RS01085 () | 204345..205016 | - | 672 | WP_002301116.1 | ABC transporter permease | - |
| CO994_RS01090 () | 205013..205930 | - | 918 | WP_002301114.1 | osmoprotectant ABC transporter substrate-binding protein | - |
| CO994_RS01095 () | 205927..206568 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
| CO994_RS01100 () | 206572..207747 | - | 1176 | WP_002348889.1 | Carnitine transport ATP-binding protein OpuCA | VF |
| CO994_RS01105 () | 207940..208971 | + | 1032 | WP_002350806.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| CO994_RS01110 () | 209165..210458 | + | 1294 | Protein_203 | ISL3 family transposase IS1251 | Transposase |
| CO994_RS01115 () | 210648..211601 | + | 954 | WP_002341590.1 | IS30 family transposase IS1252 | Transposase |
| CO994_RS01120 () | 211692..212987 | + | 1296 | WP_002319878.1 | ISL3 family transposase IS1251 | Transposase |
| CO994_RS01125 () | 213149..214444 | + | 1296 | WP_002326809.1 | ISL3 family transposase ISEfa5 | Transposase |
| CO994_RS01130 () | 215154..217793 | + | 2640 | WP_002289743.1 | cation-translocating P-type ATPase | - |
| CO994_RS01135 () | 217961..218659 | - | 699 | WP_002294185.1 | DUF975 family protein | - |
| CO994_RS01140 () | 218762..219715 | - | 954 | WP_002341590.1 | IS30 family transposase IS1252 | Transposase |
| CO994_RS01145 () | 219944..221089 | + | 1146 | WP_002294183.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| CO994_RS01150 () | 221186..221566 | + | 381 | WP_002300794.1 | preprotein translocase subunit YajC | - |
| CO994_RS01160 () | 221871..224468 | + | 2598 | WP_010782512.1 | Aldehyde-alcohol dehydrogenase | VF |
| CO994_RS01165 () | 224376..225986 | - | 1611 | WP_010782513.1 | IS1182 family transposase ISEfa7 | Transposase |
| CO994_RS01170 () | 226263..227217 | + | 955 | Protein_214 | glycoside hydrolase family 88 protein | - |
| CO994_RS01175 () | 227234..228258 | + | 1025 | Protein_215 | TRAP transporter substrate-binding protein | - |
| CO994_RS01180 () | 228264..228743 | + | 480 | WP_002300788.1 | TRAP transporter small permease | - |
| CO994_RS01185 () | 228759..229337 | + | 579 | WP_002300787.1 | TRAP transporter large permease subunit | - |
| CO994_RS01190 () | 229369..230708 | + | 1340 | WP_086953915.1 | IS3-like element ISEnfa3 family transposase | - |
| CO994_RS01195 () | 230752..230958 | + | 207 | WP_126145175.1 | TRAP transporter large permease subunit | - |
| CO994_RS01200 () | 230940..231245 | + | 306 | WP_002300046.1 | 5-dehydro-4-deoxy-D-glucuronate isomerase | - |
| CO994_RS01205 () | 231265..232068 | + | 804 | WP_033582433.1 | gluconate 5-dehydrogenase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|