MGE detailed information
MGE type: Conjugative plasmid MGE length: 154099 bp
Accession: NZ_CP021177 Location: 1..154099 Organism: Escherichia coli strain 5CRE51 Replicon: plasmid p5CRE51-NDM-9
Accession: NZ_CP021177 Location: 1..154099 Organism: Escherichia coli strain 5CRE51 Replicon: plasmid p5CRE51-NDM-9
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CA593_RS26570 () | 1..361 | - | 361 | Protein_0 | SAM-dependent methyltransferase | - |
| CA593_RS26575 () | 442..1206 | - | 765 | WP_000277497.1 | hypothetical protein | - |
| CA593_RS27945 () | 1527..1694 | + | 168 | WP_000803860.1 | hypothetical protein | - |
| CA593_RS26580 () | 1767..4157 | + | 2391 | WP_000694550.1 | Ig-like domain repeat protein | - |
| CA593_RS26585 () | 4592..5062 | + | 471 | WP_000170638.1 | hypothetical protein | - |
| CA593_RS26590 () | 5112..5408 | + | 297 | WP_000581857.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CA593_RS26595 () | 5417..6598 | + | 1182 | Protein_6 | flavin reductase family protein | - |
| CA593_RS26600 () | 7006..7383 | + | 378 | WP_000853477.1 | hypothetical protein | - |
| CA593_RS26605 () | 7478..7906 | + | 429 | WP_001133498.1 | hypothetical protein | - |
| CA593_RS26610 () | 7971..8228 | + | 258 | WP_001290637.1 | hypothetical protein | - |
| CA593_RS26615 () | 8384..8992 | + | 609 | WP_000833773.1 | hypothetical protein | - |
| CA593_RS26620 () | 9161..10411 | + | 1251 | WP_000104323.1 | site-specific DNA-methyltransferase | - |
| CA593_RS28185 () | 10692..10838 | + | 147 | WP_001426334.1 | hypothetical protein | - |
| CA593_RS26625 () | 11254..11580 | + | 327 | WP_000556022.1 | hypothetical protein | - |
| CA593_RS26630 () | 11646..11903 | + | 258 | WP_042634392.1 | hypothetical protein | - |
| CA593_RS26635 () | 12130..12921 | + | 792 | WP_046788417.1 | hypothetical protein | - |
| CA593_RS26640 () | 12973..13422 | + | 450 | WP_000182314.1 | hypothetical protein | - |
| CA593_RS26645 () | 13595..15979 | + | 2385 | WP_000469466.1 | phosphoadenosine phosphosulfate reductase family protein | - |
| CA593_RS26650 () | 16229..16468 | + | 240 | WP_001180999.1 | hypothetical protein | - |
| CA593_RS26655 () | 16531..16842 | + | 312 | WP_000172889.1 | hypothetical protein | - |
| CA593_RS26660 () | 16839..17027 | + | 189 | WP_000159618.1 | hypothetical protein | - |
| CA593_RS26665 () | 17088..17621 | + | 534 | WP_000241454.1 | HNH endonuclease | - |
| CA593_RS26670 () | 17736..18344 | + | 609 | WP_000280722.1 | hypothetical protein | - |
| CA593_RS26675 () | 18572..18799 | + | 228 | WP_000276410.1 | hypothetical protein | - |
| CA593_RS26680 () | 18979..19299 | + | 321 | WP_001133831.1 | hypothetical protein | - |
| CA593_RS26690 () | 19815..20126 | + | 312 | WP_001165367.1 | DUF957 domain-containing protein | - |
| CA593_RS26695 () | 20131..20622 | + | 492 | WP_001424592.1 | DUF3085 domain-containing protein | - |
| CA593_RS26705 () | 21175..21378 | + | 204 | WP_000781545.1 | hypothetical protein | - |
| CA593_RS26710 () | 21433..21657 | + | 225 | WP_000551490.1 | hypothetical protein | - |
| CA593_RS26715 () | 21697..21897 | + | 201 | WP_000814954.1 | hypothetical protein | - |
| CA593_RS26720 () | 22120..22431 | + | 312 | WP_001424621.1 | hypothetical protein | - |
| CA593_RS26725 () | 22806..23087 | + | 282 | WP_000703843.1 | hypothetical protein | - |
| CA593_RS26730 () | 23303..23908 | + | 606 | WP_000137793.1 | hypothetical protein | - |
| CA593_RS26735 () | 24241..25610 | + | 1370 | WP_087522250.1 | IS3 family transposase IS150 | Transposase |
| CA593_RS26740 () | 25709..25867 | + | 159 | WP_000783758.1 | type I toxin-antitoxin system Hok family toxin | - |
| CA593_RS26750 () | 26286..26489 | - | 204 | WP_001015182.1 | hypothetical protein | - |
| CA593_RS26755 () | 26535..26885 | - | 351 | WP_000743060.1 | hypothetical protein | - |
| CA593_RS26760 () | 26945..27544 | - | 600 | WP_001031421.1 | hypothetical protein | - |
| CA593_RS26765 () | 27644..28588 | - | 945 | WP_000778030.1 | DUF5417 domain-containing protein | - |
| CA593_RS28190 () | 29098..29274 | + | 177 | WP_001371930.1 | hypothetical protein | - |
| CA593_RS26780 () | 29690..30874 | + | 1185 | WP_001272970.1 | hypothetical protein | - |
| CA593_RS26785 () | 30940..31221 | + | 282 | WP_000710431.1 | hypothetical protein | - |
| CA593_RS26790 () | 31478..31684 | + | 207 | WP_000893963.1 | hypothetical protein | - |
| CA593_RS26795 () | 31805..32101 | + | 297 | WP_000744346.1 | hypothetical protein | - |
| CA593_RS26800 () | 32146..32583 | + | 438 | WP_000286107.1 | hypothetical protein | - |
| CA593_RS26805 () | 32651..33187 | + | 537 | WP_000800252.1 | hypothetical protein | - |
| CA593_RS26810 () | 33352..33720 | + | 369 | WP_000537761.1 | hypothetical protein | - |
| CA593_RS26815 () | 34153..34455 | + | 303 | WP_000442694.1 | hypothetical protein | - |
| CA593_RS26820 () | 34812..35096 | + | 285 | WP_001032029.1 | hypothetical protein | - |
| CA593_RS26825 () | 35162..35515 | + | 354 | WP_000210769.1 | hypothetical protein | - |
| CA593_RS26830 () | 35951..36376 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| CA593_RS26835 () | 36373..36723 | + | 351 | WP_072647959.1 | IS66 family transposase ISEc23 | Transposase |
| CA593_RS26840 () | 36754..38367 | + | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| CA593_RS26845 () | 38354..39073 | - | 720 | WP_072647958.1 | NERD domain-containing protein | - |
| CA593_RS26850 () | 39075..40256 | - | 1182 | WP_000952983.1 | S49 family peptidase | - |
| CA593_RS26855 () | 40267..40929 | - | 663 | WP_000718549.1 | DUF4400 domain-containing protein | - |
| CA593_RS26860 () | 40916..42025 | - | 1110 | WP_046788496.1 | hypothetical protein | - |
| CA593_RS26865 () | 42025..44109 | - | 2085 | WP_046788497.1 | conjugative transfer system coupling protein TraD | - |
| CA593_RS26870 () | 44109..47255 | - | 3147 | WP_001011151.1 | hypothetical protein | Relaxase |
| CA593_RS26875 () | 47265..48002 | - | 738 | WP_000128631.1 | hypothetical protein | - |
| CA593_RS26880 () | 47999..48484 | - | 486 | WP_000071885.1 | hypothetical protein | - |
| CA593_RS26885 () | 49243..50043 | + | 801 | WP_000004209.1 | hypothetical protein | - |
| CA593_RS26890 () | 50045..50557 | + | 513 | WP_001140953.1 | hypothetical protein | - |
| CA593_RS26895 () | 51151..52197 | + | 1047 | WP_000196728.1 | thioredoxin family protein | - |
| CA593_RS26900 () | 52187..53602 | + | 1416 | WP_001257292.1 | IncHI-type conjugal transfer protein TrhH | - |
| CA593_RS26905 () | 53611..57564 | + | 3954 | WP_072647581.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| CA593_RS26910 () | 57745..59034 | + | 1290 | WP_001284752.1 | HNH endonuclease | - |
| CA593_RS26915 () | 59142..59660 | - | 519 | WP_015059500.1 | hypothetical protein | - |
| CA593_RS26920 () | 59791..60330 | - | 540 | WP_000494967.1 | hypothetical protein | VF |
| CA593_RS26925 () | 60478..61227 | + | 750 | WP_000720274.1 | thioredoxin fold domain-containing protein | - |
| CA593_RS26930 () | 61252..61644 | + | 393 | WP_000843244.1 | hypothetical protein | - |
| CA593_RS26935 () | 61678..62100 | + | 423 | WP_000025803.1 | hypothetical protein | - |
| CA593_RS26940 () | 62160..62771 | - | 612 | WP_000620990.1 | hypothetical protein | - |
| CA593_RS26945 () | 62878..63687 | + | 810 | WP_000031377.1 | DsbA family protein | - |
| CA593_RS26950 () | 63733..64992 | - | 1260 | WP_042634445.1 | translesion error-prone DNA polymerase V subunit UmuC | - |
| CA593_RS26955 () | 64976..65410 | - | 435 | WP_000111290.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| CA593_RS26960 () | 65604..66221 | + | 618 | WP_001130842.1 | hypothetical protein | - |
| CA593_RS26965 () | 66371..66727 | + | 357 | WP_000770127.1 | hypothetical protein | - |
| CA593_RS27950 () | 66978..67148 | + | 171 | WP_152919720.1 | hypothetical protein | - |
| CA593_RS26970 () | 67185..67889 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| CA593_RS26980 () | 67941..68384 | + | 444 | Protein_80 | relaxase | - |
| CA593_RS26985 () | 68384..69010 | + | 627 | WP_000434930.1 | hypothetical protein | - |
| CA593_RS26990 () | 69074..69265 | + | 192 | Protein_82 | transposase | - |
| CA593_RS26995 () | 69515..70390 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| CA593_RS27955 () | 70425..70565 | + | 141 | Protein_84 | IS5/IS1182 family transposase | - |
| CA593_RS27005 () | 70628..71332 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CA593_RS27015 () | 71342..71812 | + | 471 | WP_049824851.1 | TetR family transcriptional regulator | - |
| CA593_RS27020 () | 71832..72620 | + | 789 | WP_014839978.1 | winged helix-turn-helix domain-containing protein | - |
| CA593_RS27025 () | 72620..73138 | + | 519 | WP_014839979.1 | hypothetical protein | - |
| CA593_RS27030 () | 73143..73559 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| CA593_RS27035 () | 73945..74649 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CA593_RS27045 () | 74924..75937 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| CA593_RS27050 () | 76082..76579 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| CA593_RS27960 () | 76690..76980 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| CA593_RS27055 () | 76986..77777 | + | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CA593_RS27060 () | 77941..78288 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CA593_RS27065 () | 78282..79121 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| CA593_RS27070 () | 79526..81067 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| CA593_RS27075 () | 81508..81837 | + | 330 | WP_004201171.1 | divalent-cation tolerance protein CutA | - |
| CA593_RS27080 () | 81842..82873 | + | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| CA593_RS27085 () | 82884..83522 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| CA593_RS27090 () | 83527..83892 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| CA593_RS27095 () | 83896..84708 | - | 813 | WP_032495672.1 | Metallo-beta-lactamase type 2 | ARG |
| CA593_RS27100 () | 84809..85012 | - | 204 | WP_072649515.1 | hypothetical protein | - |
| CA593_RS27105 () | 85003..85707 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| CA593_RS27110 () | 85761..86213 | + | 453 | Protein_105 | Tyrosine recombinase XerD | VF |
| CA593_RS27120 () | 86497..87201 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| CA593_RS27965 () | 87316..87594 | + | 279 | WP_004217866.1 | DUF3330 domain-containing protein | - |
| CA593_RS27135 () | 87720..88280 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| CA593_RS27140 () | 88283..91249 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| CA593_RS27145 () | 91258..91659 | + | 402 | WP_046788546.1 | hypothetical protein | - |
| CA593_RS27150 () | 91744..92448 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| CA593_RS27155 () | 92512..93342 | + | 831 | Protein_112 | IS91 family transposase ISVsa3 | Transposase |
| CA593_RS28195 () | 93811..94257 | + | 447 | Protein_113 | DUF3363 domain-containing protein | - |
| CA593_RS27165 () | 94474..95688 | + | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
| CA593_RS27170 () | 95716..96021 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| CA593_RS27175 () | 96133..96786 | + | 654 | Protein_116 | IS91 family transposase ISPps1 | Transposase |
| CA593_RS27180 () | 96839..97543 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CA593_RS27190 () | 97609..99123 | + | 1515 | Protein_118 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| CA593_RS27195 () | 99233..99583 | + | 351 | WP_072647511.1 | hypothetical protein | - |
| CA593_RS27200 () | 99960..100277 | + | 318 | WP_029698059.1 | hypothetical protein | - |
| CA593_RS27205 () | 100328..100735 | - | 408 | WP_000074418.1 | hypothetical protein | - |
| CA593_RS27970 () | 100765..101226 | - | 462 | WP_000185304.1 | hypothetical protein | - |
| CA593_RS27215 () | 101563..101793 | - | 231 | WP_001572393.1 | hypothetical protein | - |
| CA593_RS27230 () | 102455..102688 | - | 234 | WP_015059496.1 | hypothetical protein | - |
| CA593_RS27235 () | 102910..103806 | - | 897 | WP_000975182.1 | hypothetical protein | - |
| CA593_RS27240 () | 103809..104324 | - | 516 | WP_001572389.1 | thermonuclease family protein | - |
| CA593_RS27245 () | 104539..105966 | + | 1428 | WP_000833382.1 | DNA cytosine methyltransferase | - |
| CA593_RS28200 () | 106027..106194 | + | 168 | WP_000220758.1 | hypothetical protein | - |
| CA593_RS27255 () | 106217..107536 | + | 1320 | WP_000078514.1 | DUF1173 family protein | - |
| CA593_RS27265 () | 107816..109021 | - | 1206 | WP_001572381.1 | hypothetical protein | - |
| CA593_RS27270 () | 109018..109836 | - | 819 | WP_000193209.1 | DUF4942 domain-containing protein | - |
| CA593_RS27275 () | 110479..110859 | + | 381 | WP_001426317.1 | hypothetical protein | - |
| CA593_RS27280 () | 110917..111582 | + | 666 | WP_000490638.1 | hypothetical protein | - |
| CA593_RS27285 () | 111642..112097 | + | 456 | WP_001572344.1 | hypothetical protein | - |
| CA593_RS27290 () | 112139..112375 | + | 237 | WP_000175476.1 | hypothetical protein | - |
| CA593_RS27300 () | 112873..113277 | + | 405 | WP_001287392.1 | H-NS histone family protein | - |
| CA593_RS27310 () | 113619..113822 | - | 204 | WP_001194555.1 | hypothetical protein | - |
| CA593_RS27315 () | 113884..114267 | - | 384 | Protein_138 | HNH endonuclease | - |
| CA593_RS27320 () | 114853..115839 | + | 987 | WP_001572342.1 | hypothetical protein | - |
| CA593_RS27325 () | 115836..117875 | + | 2040 | WP_032192809.1 | ATP-dependent helicase | - |
| CA593_RS27980 () | 118188..118487 | - | 300 | WP_001572440.1 | hypothetical protein | - |
| CA593_RS27340 () | 118542..118778 | - | 237 | Protein_142 | hypothetical protein | - |
| CA593_RS27345 () | 119232..119657 | - | 426 | WP_001043843.1 | hypothetical protein | - |
| CA593_RS27350 () | 119911..120726 | - | 816 | WP_001572439.1 | HNH endonuclease | - |
| CA593_RS27355 () | 120739..121149 | - | 411 | WP_000985911.1 | hypothetical protein | - |
| CA593_RS27360 () | 121251..121457 | - | 207 | WP_000134171.1 | hypothetical protein | - |
| CA593_RS27365 () | 121518..122843 | - | 1326 | WP_000088046.1 | type II toxin-antitoxin system HipA family toxin | Toxin Detail |
| CA593_RS27370 () | 122848..123141 | - | 294 | WP_024136327.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| CA593_RS27380 () | 123745..124137 | - | 393 | WP_000341066.1 | hypothetical protein | - |
| CA593_RS27385 () | 124510..124851 | + | 342 | WP_001151575.1 | hypothetical protein | - |
| CA593_RS27390 () | 124943..125134 | + | 192 | WP_000398480.1 | hypothetical protein | - |
| CA593_RS27395 () | 125184..125465 | + | 282 | WP_000077926.1 | hypothetical protein | - |
| CA593_RS27400 () | 126028..127269 | - | 1242 | WP_001053338.1 | VWA domain-containing protein | - |
| CA593_RS27410 () | 127698..128273 | - | 576 | WP_000301242.1 | TerD family protein | - |
| CA593_RS27415 () | 128341..128919 | - | 579 | WP_000116677.1 | tellurium resistance membrane protein TerD | - |
| CA593_RS27420 () | 128968..130008 | - | 1041 | WP_000255079.1 | tellurium resistance membrane protein TerC | - |
| CA593_RS27425 () | 130031..130486 | - | 456 | WP_000007448.1 | tellurite resistance TerB family protein | - |
| CA593_RS27430 () | 130509..131666 | - | 1158 | WP_001054787.1 | TerD family protein | - |
| CA593_RS27435 () | 131666..132247 | - | 582 | WP_042634303.1 | tellurium resistance TerZ family protein | - |
| CA593_RS27440 () | 132571..133629 | + | 1059 | WP_001035162.1 | ATP-grasp domain-containing protein | - |
| CA593_RS27445 () | 133639..134781 | + | 1143 | WP_001285478.1 | phosphoribosyltransferase domain-containing protein | - |
| CA593_RS27450 () | 134774..135547 | + | 774 | WP_001040059.1 | hypothetical protein | - |
| CA593_RS27455 () | 135549..136628 | + | 1080 | WP_042634304.1 | cysteine protease StiP family protein | - |
| CA593_RS27460 () | 136628..137584 | + | 957 | WP_000797366.1 | HpcH/HpaI aldolase/citrate lyase family protein | - |
| CA593_RS27465 () | 137595..138803 | + | 1209 | WP_000506887.1 | DUF4236 domain-containing protein | - |
| CA593_RS27470 () | 138821..139288 | + | 468 | WP_001176767.1 | tellurium resistance protein TerW | - |
| CA593_RS27475 () | 139751..140389 | + | 639 | WP_001388628.1 | VWA domain-containing protein | - |
| CA593_RS27480 () | 140412..141053 | + | 642 | WP_000116681.1 | TerD family protein | - |
| CA593_RS27485 () | 141053..141691 | + | 639 | WP_001253658.1 | VWA domain-containing protein | - |
| CA593_RS27490 () | 141777..142817 | + | 1041 | WP_001253653.1 | VWA domain-containing protein | - |
| CA593_RS27495 () | 142817..144454 | + | 1638 | WP_000081622.1 | protein phosphatase 2C domain-containing protein | - |
| CA593_RS27500 () | 144480..145979 | + | 1500 | WP_001284313.1 | kinase | - |
| CA593_RS27505 () | 146146..147228 | - | 1083 | WP_001232449.1 | hypothetical protein | - |
| CA593_RS27510 () | 147589..147801 | - | 213 | WP_001285422.1 | hypothetical protein | - |
| CA593_RS27515 () | 147972..149147 | + | 1176 | WP_000795947.1 | tyrosine-type recombinase/integrase | - |
| CA593_RS27520 () | 149169..149513 | - | 345 | WP_001805195.1 | hypothetical protein | - |
| CA593_RS27525 () | 149449..150354 | - | 906 | WP_001198594.1 | hypothetical protein | - |
| CA593_RS27530 () | 150364..151326 | - | 963 | WP_000119427.1 | DNA replication protein | - |
| CA593_RS27535 () | 151417..151800 | - | 384 | WP_001424628.1 | hypothetical protein | - |
| CA593_RS27540 () | 151880..152416 | - | 537 | WP_000107168.1 | hypothetical protein | - |
| CA593_RS27545 () | 152490..152747 | - | 258 | WP_001371933.1 | hypothetical protein | - |
| CA593_RS27550 () | 152755..153345 | - | 591 | WP_000578892.1 | hypothetical protein | - |
| CA593_RS27555 () | 153390..153665 | - | 276 | WP_001004201.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|