MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 129878 bp
Accession: NZ_CP018830 Location: 92764..222641 Organism: Enterococcus faecium strain ISMMS_VRE_9 Replicon: chromosome
Accession: NZ_CP018830 Location: 92764..222641 Organism: Enterococcus faecium strain ISMMS_VRE_9 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AL023_RS00520 () | 87866..88054 | - | 189 | WP_002290463.1 | 50S ribosomal protein L28 | - |
| AL023_RS00530 () | 88324..88686 | + | 363 | WP_002294298.1 | Asp23/Gls24 family envelope stress response protein | - |
| AL023_RS00535 () | 88738..90420 | + | 1683 | WP_002301169.1 | DAK2 domain-containing protein | - |
| AL023_RS00540 () | 90537..92573 | + | 2037 | WP_002301167.1 | ATP-dependent DNA helicase RecG | - |
| AL023_RS00545 () | 92622..93623 | + | 1002 | WP_002289721.1 | phosphate acyltransferase PlsX | - |
| AL023_RS00550 () | 93745..93987 | + | 243 | WP_002294295.1 | Endonuclease 4 | VF |
| AL023_RS00555 () | 94255..95259 | + | 1005 | WP_002287889.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| AL023_RS00560 () | 95260..96204 | + | 945 | WP_002287891.1 | Cyclic di-GMP phosphodiesterase CdpA | VF |
| AL023_RS00565 () | 96204..97166 | + | 963 | WP_002287892.1 | ABC transporter permease | - |
| AL023_RS00570 () | 97193..98107 | + | 915 | WP_002287893.1 | ABC transporter permease | - |
| AL023_RS00575 () | 98133..99914 | + | 1782 | WP_002287894.1 | oligopeptide ABC transporter substrate-binding protein | - |
| AL023_RS00580 () | 100262..100948 | + | 687 | WP_002287896.1 | ribonuclease III | - |
| AL023_RS00585 () | 100968..104549 | + | 3582 | WP_002301166.1 | chromosome segregation protein SMC | - |
| AL023_RS00590 () | 104558..105367 | + | 810 | WP_002348798.1 | Cof-type HAD-IIB family hydrolase | - |
| AL023_RS00595 () | 105379..106377 | + | 999 | WP_002301165.1 | signal recognition particle-docking protein FtsY | - |
| AL023_RS00600 () | 106564..108831 | + | 2268 | WP_002294288.1 | bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB | - |
| AL023_RS00605 () | 109015..109968 | + | 954 | WP_002326066.1 | IS30 family transposase IS1252 | Transposase |
| AL023_RS00610 () | 109986..110438 | - | 453 | WP_002294287.1 | YueI family protein | - |
| AL023_RS00615 () | 110588..111538 | + | 951 | WP_002294286.1 | Vitamin B12 import system permease protein BtuC | VF |
| AL023_RS00620 () | 111531..112490 | + | 960 | WP_002301163.1 | Vitamin B12 import system permease protein BtuC | VF |
| AL023_RS00625 () | 112487..113242 | + | 756 | WP_002301162.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| AL023_RS00630 () | 113265..114218 | + | 954 | WP_002301160.1 | putative S-adenosylmethionine-dependent methyltransferase/MSMEI_2290 | VF |
| AL023_RS00635 () | 114862..115158 | - | 297 | WP_002287909.1 | phenylalanyl-tRNA synthetase subunit alpha | - |
| AL023_RS00640 () | 115514..115870 | + | 357 | WP_002287910.1 | iron-sulfur cluster biosynthesis family protein | - |
| AL023_RS00645 () | 115880..116779 | + | 900 | WP_002348747.1 | metallophosphoesterase | - |
| AL023_RS00650 () | 117012..117971 | - | 960 | WP_010782507.1 | IS30 family transposase IS1062 | Transposase |
| AL023_RS00655 () | 118229..119674 | + | 1446 | WP_010782508.1 | IS1182 family transposase ISEfa7 | Transposase |
| AL023_RS00660 () | 119720..120454 | - | 735 | WP_002348590.1 | aquaporin family protein | - |
| AL023_RS00665 () | 120780..121190 | + | 411 | WP_002301190.1 | CidA/LrgA family protein | - |
| AL023_RS00670 () | 121183..121884 | + | 702 | WP_002294273.1 | LrgB family protein | - |
| AL023_RS00675 () | 121884..123497 | + | 1614 | WP_002348592.1 | helix-turn-helix domain-containing protein | - |
| AL023_RS00680 () | 123487..123708 | + | 222 | WP_002290506.1 | DUF2829 domain-containing protein | - |
| AL023_RS00685 () | 123705..124466 | + | 762 | WP_002297929.1 | Amidophosphoribosyltransferase | VF |
| AL023_RS00690 () | 124847..125356 | + | 510 | WP_002294268.1 | QueT transporter family protein | - |
| AL023_RS00695 () | 125426..125965 | - | 540 | WP_002294267.1 | biotin transporter BioY | - |
| AL023_RS00700 () | 126105..126716 | - | 612 | WP_002294265.1 | 30S ribosomal protein S4 | - |
| AL023_RS00705 () | 126978..127829 | + | 852 | WP_002348593.1 | formate/nitrite transporter family protein | - |
| AL023_RS00710 () | 127857..128492 | + | 636 | WP_002294262.1 | DNA alkylation repair protein | - |
| AL023_RS00715 () | 128512..129285 | + | 774 | WP_002294261.1 | Cof-type HAD-IIB family hydrolase | - |
| AL023_RS00725 () | 129693..130490 | + | 798 | WP_002348595.1 | TIGR00282 family metallophosphoesterase | - |
| AL023_RS00730 () | 130468..130881 | + | 414 | WP_002297923.1 | YlbF family regulator | - |
| AL023_RS00735 () | 130865..133510 | + | 2646 | WP_002294258.1 | DNA mismatch repair protein MutS | - |
| AL023_RS00740 () | 133528..135636 | + | 2109 | WP_002301736.1 | DNA mismatch repair endonuclease MutL | - |
| AL023_RS00745 () | 135658..136218 | + | 561 | WP_002348596.1 | septum formation inhibitor Maf | - |
| AL023_RS00750 () | 136357..137652 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| AL023_RS00755 () | 137912..138106 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| AL023_RS00760 () | 138096..138449 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| AL023_RS00765 () | 138551..140098 | + | 1548 | WP_002296127.1 | IS66 family transposase ISRob1 | Transposase |
| AL023_RS00770 () | 140178..142166 | - | 1989 | WP_002348864.1 | PTS system trehalose-specific EIIBC component | - |
| AL023_RS00775 () | 142389..143102 | + | 714 | WP_002294254.1 | trehalose operon repressor | - |
| AL023_RS00780 () | 143179..143625 | + | 447 | WP_002294252.1 | GTP 3',8-cyclase 1 | VF |
| AL023_RS00785 () | 143795..144397 | + | 603 | WP_002290528.1 | Holliday junction branch migration protein RuvA | - |
| AL023_RS00790 () | 144410..145411 | + | 1002 | WP_002289812.1 | Holliday junction ATP-dependent DNA helicase RuvB | VF |
| AL023_RS00795 () | 145440..146018 | + | 579 | WP_002341570.1 | TetR/AcrR family transcriptional regulator | - |
| AL023_RS00800 () | 146070..146552 | + | 483 | WP_002294249.1 | D-amino acid dehydrogenase | VF |
| AL023_RS00805 () | 146669..147043 | + | 375 | WP_002289815.1 | hypothetical protein | - |
| AL023_RS00820 () | 147843..149195 | - | 1353 | WP_002294246.1 | branched-chain amino acid transport system II carrier protein | - |
| AL023_RS00825 () | 149342..149932 | + | 591 | WP_002297079.1 | DUF1211 domain-containing protein | - |
| AL023_RS00835 () | 150060..151409 | - | 1350 | WP_002294242.1 | amino acid permease | - |
| AL023_RS00840 () | 151577..152317 | - | 741 | WP_002294240.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| AL023_RS00845 () | 152330..153922 | - | 1593 | WP_002297081.1 | ABC transporter permease subunit | - |
| AL023_RS00855 () | 154490..154786 | - | 297 | WP_002293448.1 | hypothetical protein | - |
| AL023_RS00860 () | 154962..155687 | + | 726 | WP_002294236.1 | NAD-dependent protein deacylase | - |
| AL023_RS00865 () | 155680..156522 | + | 843 | WP_002301156.1 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase | VF |
| AL023_RS00870 () | 156525..157046 | + | 522 | WP_002294232.1 | transcription repressor NadR | - |
| AL023_RS00880 () | 157299..157862 | - | 564 | WP_002289284.1 | peptide deformylase | - |
| AL023_RS00885 () | 158113..158382 | + | 270 | WP_002289282.1 | 30S ribosomal protein S15 | - |
| AL023_RS00890 () | 158570..160696 | + | 2127 | WP_002297086.1 | polyribonucleotide nucleotidyltransferase | - |
| AL023_RS00895 () | 161206..161472 | + | 267 | WP_002289280.1 | GlsB/YeaQ/YmgE family stress response membrane protein | - |
| AL023_RS00900 () | 161649..163607 | + | 1959 | WP_002321207.1 | KUP/HAK/KT family potassium transporter | - |
| AL023_RS00905 () | 163961..165262 | + | 1302 | WP_002294228.1 | hemolysin family protein | - |
| AL023_RS00910 () | 165638..166933 | - | 1296 | WP_002326809.1 | ISL3 family transposase ISEfa5 | Transposase |
| AL023_RS00915 () | 167070..168179 | - | 1110 | Protein_166 | IS110 family transposase ISSsu7 | Transposase |
| AL023_RS00920 () | 168526..169896 | - | 1371 | WP_002289277.1 | MATE family efflux transporter | - |
| AL023_RS00925 () | 170078..170401 | - | 324 | WP_002289744.1 | DUF960 domain-containing protein | - |
| AL023_RS00930 () | 170726..171334 | - | 609 | WP_002299254.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| AL023_RS00935 () | 171664..172380 | + | 717 | WP_002348768.1 | pseudouridine synthase | - |
| AL023_RS00940 () | 172393..173088 | + | 696 | WP_002289749.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| AL023_RS00945 () | 173172..173801 | + | 630 | WP_002289751.1 | uridine kinase | - |
| AL023_RS16810 () | 174316..175655 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| AL023_RS00960 () | 175724..176326 | + | 603 | WP_002294220.1 | TVP38/TMEM64 family protein | - |
| AL023_RS00965 () | 176348..176836 | + | 489 | WP_002296548.1 | GNAT family N-acetyltransferase | - |
| AL023_RS00970 () | 177157..178530 | + | 1374 | WP_002294217.1 | hypothetical protein | - |
| AL023_RS00975 () | 178514..178981 | + | 468 | WP_002294214.1 | YaiI/YqxD family protein | - |
| AL023_RS00980 () | 179230..180975 | - | 1746 | WP_002329999.1 | AarF/ABC1/UbiB kinase family protein | - |
| AL023_RS00985 () | 181171..182247 | + | 1077 | WP_002293424.1 | D-alanine--D-alanine ligase | - |
| AL023_RS00990 () | 182400..183752 | + | 1353 | WP_002317074.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| AL023_RS00995 () | 184074..185585 | + | 1512 | WP_002294211.1 | DEAD/DEAH box helicase | - |
| AL023_RS01000 () | 185715..186065 | + | 351 | WP_002294209.1 | holo-ACP synthase | - |
| AL023_RS01005 () | 186081..187202 | + | 1122 | WP_002294207.1 | alanine racemase | - |
| AL023_RS01010 () | 187213..187575 | + | 363 | WP_002289874.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| AL023_RS01020 () | 187751..188020 | - | 270 | WP_002293413.1 | 30S ribosomal protein S14 | - |
| AL023_RS01025 () | 188210..189157 | + | 948 | WP_002294206.1 | NADP-dependent oxidoreductase | - |
| AL023_RS01030 () | 189303..190598 | - | 1296 | WP_016171130.1 | ISL3 family transposase ISEfa5 | Transposase |
| AL023_RS01035 () | 190865..191824 | + | 960 | WP_002301399.1 | IS30 family transposase IS1062 | Transposase |
| AL023_RS01040 () | 192050..194755 | + | 2706 | WP_002294203.1 | YhgE/Pip domain-containing protein | - |
| AL023_RS01050 () | 195352..197175 | + | 1824 | WP_002294202.1 | APC family permease | - |
| AL023_RS01055 () | 197317..197502 | - | 186 | WP_002348885.1 | hypothetical protein | - |
| AL023_RS01065 () | 197977..198240 | + | 264 | WP_002294199.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| AL023_RS01070 () | 198240..198506 | + | 267 | WP_002301121.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| AL023_RS17120 () | 198707..199541 | + | 835 | Protein_194 | hypothetical protein | - |
| AL023_RS01085 () | 199737..200408 | - | 672 | WP_002301116.1 | ABC transporter permease | - |
| AL023_RS01090 () | 200405..201322 | - | 918 | WP_002301114.1 | osmoprotectant ABC transporter substrate-binding protein | - |
| AL023_RS01095 () | 201319..201960 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
| AL023_RS01100 () | 201964..203139 | - | 1176 | WP_002348889.1 | NADH-quinone oxidoreductase subunit 6 | VF |
| AL023_RS01105 () | 203332..204363 | + | 1032 | WP_002350806.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| AL023_RS01110 () | 204557..205850 | + | 1294 | Protein_200 | ISL3 family transposase IS1251 | Transposase |
| AL023_RS01115 () | 206040..206993 | + | 954 | WP_002341590.1 | IS30 family transposase IS1252 | Transposase |
| AL023_RS01120 () | 207084..208379 | + | 1296 | WP_002319878.1 | ISL3 family transposase IS1251 | Transposase |
| AL023_RS01125 () | 208541..209836 | + | 1296 | WP_002326809.1 | ISL3 family transposase ISEfa5 | Transposase |
| AL023_RS01130 () | 210546..213185 | + | 2640 | WP_002289743.1 | cation-translocating P-type ATPase | - |
| AL023_RS01135 () | 213353..214051 | - | 699 | WP_002294185.1 | DUF975 family protein | - |
| AL023_RS01140 () | 214154..215107 | - | 954 | WP_002341590.1 | IS30 family transposase IS1252 | Transposase |
| AL023_RS01145 () | 215336..216481 | + | 1146 | WP_002294183.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| AL023_RS01150 () | 216578..216958 | + | 381 | WP_002300794.1 | preprotein translocase subunit YajC | - |
| AL023_RS01160 () | 217263..219860 | + | 2598 | WP_010782512.1 | NADH-quinone oxidoreductase subunit N | VF |
| AL023_RS01165 () | 219768..221378 | - | 1611 | WP_010782513.1 | IS1182 family transposase ISEfa7 | Transposase |
| AL023_RS01170 () | 221655..222609 | + | 955 | Protein_211 | glycoside hydrolase family 88 protein | - |
| AL023_RS01175 () | 222626..223650 | + | 1025 | Protein_212 | TRAP transporter substrate-binding protein | - |
| AL023_RS01180 () | 223656..224135 | + | 480 | WP_002300788.1 | TRAP transporter small permease | - |
| AL023_RS01185 () | 224151..224705 | + | 555 | Protein_214 | TRAP transporter large permease subunit | - |
| AL023_RS16815 () | 224761..226100 | + | 1340 | WP_086953915.1 | IS3-like element ISEnfa3 family transposase | - |
| AL023_RS01200 () | 226144..226350 | + | 207 | WP_126145175.1 | TRAP transporter large permease subunit | - |
| AL023_RS01205 () | 226332..226637 | + | 306 | WP_002300046.1 | 5-dehydro-4-deoxy-D-glucuronate isomerase | - |
| AL023_RS01210 () | 226657..227460 | + | 804 | WP_033582433.1 | gluconate 5-dehydrogenase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|