MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 156517 bp
Accession: NZ_CP011331 Location: 68342..224858 Organism: Escherichia coli O104:H4 str. C227-11 isolate 368 shch Replicon: chromosome
Accession: NZ_CP011331 Location: 68342..224858 Organism: Escherichia coli O104:H4 str. C227-11 isolate 368 shch Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AAF13_RS00325 () | 64328..65761 | + | 1434 | WP_000869178.1 | bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE | - |
| - () | 65841..65982 | + | 142 | NuclAT_6 | - | - |
| - () | 65841..65982 | + | 142 | NuclAT_6 | - | - |
| - () | 65841..65982 | + | 142 | NuclAT_6 | - | - |
| - () | 65841..65982 | + | 142 | NuclAT_6 | - | - |
| AAF13_RS31010 () | 65881..65940 | - | 60 | WP_001387082.1 | type I toxin-antitoxin system Ibs family toxin | - |
| - () | 66217..66358 | + | 142 | NuclAT_1 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_1 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_1 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_1 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_7 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_7 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_7 | - | - |
| - () | 66217..66358 | + | 142 | NuclAT_7 | - | - |
| AAF13_RS31020 () | 66257..66316 | - | 60 | WP_001387081.1 | type I toxin-antitoxin system Ibs family toxin | - |
| AAF13_RS00340 () | 66555..68216 | - | 1662 | WP_000341046.1 | flotillin family protein | - |
| AAF13_RS00345 () | 68243..68872 | - | 630 | WP_000599947.1 | DUF1449 family protein | - |
| AAF13_RS00350 () | 69141..69341 | + | 201 | WP_000350095.1 | cell surface composition regulator GlgS | - |
| AAF13_RS00355 () | 69384..70448 | - | 1065 | WP_001269793.1 | fimbrial protein | - |
| AAF13_RS00360 () | 70450..71199 | - | 750 | WP_001387080.1 | Chaperone protein PapD | VF |
| AAF13_RS00365 () | 71215..73719 | - | 2505 | WP_000277116.1 | Outer membrane usher protein PapC | VF |
| AAF13_RS00370 () | 73779..74330 | - | 552 | WP_001272149.1 | putative fimbrial-like protein YbgD | VF |
| AAF13_RS00375 () | 74613..74903 | - | 291 | WP_001297598.1 | IS1182 family transposase ISBusp4 | Transposase |
| AAF13_RS00380 () | 75277..75930 | + | 654 | WP_001076997.1 | 3,4-dihydroxy-2-butanone-4-phosphate synthase | - |
| AAF13_RS32035 () | 76191..76361 | + | 171 | WP_000469266.1 | hypothetical protein | - |
| AAF13_RS00390 () | 76419..77192 | - | 774 | WP_001295627.1 | zinc transporter ZupT | - |
| AAF13_RS00395 () | 77335..78123 | + | 789 | WP_001299419.1 | 4,5-DOPA dioxygenase extradiol | - |
| AAF13_RS00400 () | 78161..79321 | - | 1161 | WP_000442859.1 | glutathionylspermidine synthase family protein | - |
| AAF13_RS00405 () | 79327..79998 | - | 672 | WP_000831543.1 | DUF1190 family protein | - |
| AAF13_RS00415 () | 80146..81627 | - | 1482 | WP_000735278.1 | outer membrane channel protein TolC | - |
| AAF13_RS00420 () | 81832..82461 | + | 630 | WP_000917117.1 | ADP-ribose diphosphatase | - |
| AAF13_RS00425 () | 82462..82884 | + | 423 | WP_000833393.1 | DUF1249 family protein | - |
| AAF13_RS00430 () | 82909..83736 | + | 828 | WP_000444747.1 | 3',5'-cyclic-AMP phosphodiesterase | - |
| AAF13_RS00435 () | 83736..84317 | + | 582 | WP_000105733.1 | esterase YqiA | - |
| AAF13_RS00440 () | 84346..86238 | + | 1893 | WP_000195296.1 | DNA topoisomerase IV subunit B | - |
| AAF13_RS00445 () | 86286..86600 | - | 315 | WP_000958598.1 | antibiotic biosynthesis monooxygenase | - |
| AAF13_RS00450 () | 86631..87212 | - | 582 | WP_000065430.1 | NADPH:quinone oxidoreductase MdaB | - |
| AAF13_RS00455 () | 87531..87863 | + | 333 | WP_000912120.1 | DUF2645 family protein | - |
| AAF13_RS00460 () | 87909..89258 | - | 1350 | WP_000673354.1 | two-component system sensor histidine kinase QseC | - |
| AAF13_RS00465 () | 89255..89914 | - | 660 | WP_001221502.1 | Transcriptional regulatory protein QseB | VF |
| AAF13_RS00470 () | 90066..90458 | + | 393 | WP_000712658.1 | OB fold stress tolerance protein YgiW | - |
| AAF13_RS00475 () | 90511..90993 | + | 483 | WP_000183494.1 | transcriptional regulator | - |
| AAF13_RS00480 () | 91539..93797 | + | 2259 | WP_001281881.1 | DNA topoisomerase IV subunit A | - |
| AAF13_RS00485 () | 94030..94767 | + | 738 | WP_000965703.1 | 1-acylglycerol-3-phosphate O-acyltransferase | - |
| AAF13_RS00490 () | 94842..96254 | + | 1413 | WP_000059395.1 | cell division protein FtsP | - |
| AAF13_RS00495 () | 96365..98584 | + | 2220 | WP_000095187.1 | YgiQ family radical SAM protein | - |
| AAF13_RS00500 () | 98627..98884 | - | 258 | WP_000848528.1 | lipoprotein YqhH | - |
| AAF13_RS00505 () | 98935..99861 | - | 927 | WP_000691598.1 | YbjP/YqhG family protein | - |
| AAF13_RS00510 () | 100061..100888 | - | 828 | WP_000013149.1 | 2,5-didehydrogluconate reductase DkgA | - |
| AAF13_RS00515 () | 100993..102156 | - | 1164 | WP_001058807.1 | alcohol dehydrogenase | - |
| AAF13_RS00525 () | 102350..103249 | + | 900 | WP_024174618.1 | DNA-binding transcriptional regulator YqhC | - |
| AAF13_RS00530 () | 103289..103948 | - | 660 | WP_000268419.1 | DedA family protein | - |
| AAF13_RS00535 () | 104088..105275 | - | 1188 | WP_001315867.1 | cystathionine beta-lyase | - |
| AAF13_RS00545 () | 105527..106261 | + | 735 | WP_000527844.1 | tol-pal system-associated acyl-CoA thioesterase | - |
| AAF13_RS00550 () | 106268..106693 | + | 426 | WP_001240712.1 | TonB system transport protein ExbD | - |
| AAF13_RS00555 () | 106732..107616 | - | 885 | WP_000018758.1 | putative oxidoreductase YghA | VF |
| AAF13_RS00560 () | 107807..108301 | + | 495 | WP_000439331.1 | TIGR00645 family protein | - |
| AAF13_RS00565 () | 108341..109381 | - | 1041 | WP_000262151.1 | L-glyceraldehyde 3-phosphate reductase | - |
| AAF13_RS00570 () | 109538..110425 | + | 888 | WP_001297303.1 | dienelactone hydrolase family protein | - |
| AAF13_RS00575 () | 110544..110831 | + | 288 | WP_001059136.1 | DUF2623 domain-containing protein | - |
| AAF13_RS00585 () | 111020..112138 | + | 1119 | WP_000145410.1 | hydrogenase 2 small subunit | - |
| AAF13_RS00590 () | 112141..113127 | + | 987 | WP_001081870.1 | hydrogenase 2 operon protein HybA | - |
| AAF13_RS00595 () | 113117..114295 | + | 1179 | WP_000017703.1 | Ni/Fe-hydrogenase cytochrome b subunit | - |
| AAF13_RS00600 () | 114292..115995 | + | 1704 | WP_000083065.1 | hydrogenase 2 large subunit | - |
| AAF13_RS00605 () | 115995..116489 | + | 495 | WP_001221953.1 | HyaD/HybD family hydrogenase maturation endopeptidase | - |
| AAF13_RS00610 () | 116482..116970 | + | 489 | WP_000134014.1 | hydrogenase-2 assembly chaperone | - |
| AAF13_RS00615 () | 116963..117304 | + | 342 | WP_000544953.1 | hydrogenase maturation nickel metallochaperone HypA | - |
| AAF13_RS00620 () | 117317..117565 | + | 249 | WP_000334896.1 | hydrogenase maturation factor HybG | - |
| AAF13_RS00625 () | 117687..118667 | - | 981 | WP_000399648.1 | IS110 family transposase IS621 | Transposase |
| AAF13_RS00630 () | 118967..119833 | - | 867 | WP_001387074.1 | glutathione-dependent disulfide-bond oxidoreductase | - |
| AAF13_RS00635 () | 120038..121897 | + | 1860 | WP_001297309.1 | bifunctional glutathionylspermidine amidase/synthase | - |
| AAF13_RS00640 () | 122189..123688 | + | 1500 | WP_000933258.1 | inorganic phosphate transporter PitB | - |
| AAF13_RS00645 () | 123737..124429 | - | 693 | WP_001190780.1 | thymidylate kinase | - |
| AAF13_RS00650 () | 124603..125316 | + | 714 | WP_001076097.1 | thymidylate kinase | - |
| AAF13_RS00655 () | 125348..126106 | + | 759 | WP_000339532.1 | hypothetical protein | - |
| AAF13_RS00660 () | 126152..127501 | + | 1350 | WP_000896880.1 | lipopolysaccharide biosynthesis protein | - |
| AAF13_RS00665 () | 127501..128325 | + | 825 | WP_000984978.1 | hypothetical protein | - |
| AAF13_RS00670 () | 128337..128897 | + | 561 | WP_001299422.1 | YtfJ family protein | - |
| AAF13_RS00675 () | 128928..129998 | + | 1071 | WP_000779661.1 | LPS export ABC transporter permease LptF | - |
| AAF13_RS00680 () | 129995..131074 | + | 1080 | WP_001387073.1 | LPS export ABC transporter permease LptG | - |
| AAF13_RS00685 () | 131109..132281 | - | 1173 | WP_000524972.1 | 8-amino-7-oxononanoate synthase | VF |
| AAF13_RS00690 () | 132281..132529 | - | 249 | WP_000248097.1 | acyl carrier protein | - |
| AAF13_RS00695 () | 132561..133475 | - | 915 | WP_001077177.1 | NAD-dependent epimerase/dehydratase family protein | - |
| AAF13_RS00700 () | 133472..135193 | - | 1722 | WP_001390306.1 | 4-hydroxyphenylalkanoate adenylyltransferase | VF |
| AAF13_RS00705 () | 135564..136706 | + | 1143 | WP_000388786.1 | DNA-binding protein | - |
| AAF13_RS00710 () | 136713..137477 | - | 765 | WP_001297764.1 | transcriptional regulator GlcC | - |
| AAF13_RS00715 () | 137728..139227 | + | 1500 | WP_000026117.1 | glycolate oxidase subunit GlcD | - |
| AAF13_RS00720 () | 139227..140279 | + | 1053 | WP_000943059.1 | glycolate oxidase subunit GlcE | - |
| AAF13_RS00725 () | 140290..141513 | + | 1224 | WP_001194680.1 | glycolate oxidase subunit GlcF | - |
| AAF13_RS00730 () | 141518..141922 | + | 405 | WP_000853256.1 | protein GlcG | - |
| AAF13_RS00735 () | 141944..144115 | + | 2172 | WP_000084080.1 | malate synthase G | - |
| AAF13_RS00740 () | 144471..146153 | + | 1683 | WP_000259303.1 | glycolate permease GlcA | - |
| AAF13_RS00750 () | 146639..151204 | + | 4566 | WP_001034494.1 | hypothetical protein | VF |
| AAF13_RS00755 () | 151344..152153 | + | 810 | WP_001365924.1 | Leader peptidase PppA | VF |
| AAF13_RS00760 () | 152219..152629 | + | 411 | WP_001324279.1 | type II secretion system pilot lipoprotein GspS-beta | - |
| AAF13_RS00765 () | 152647..153606 | + | 960 | WP_000135063.1 | Type II secretion system protein C | VF |
| AAF13_RS00770 () | 153636..155696 | + | 2061 | WP_000498829.1 | Type II secretion system protein D | VF |
| AAF13_RS00775 () | 155696..157189 | + | 1494 | WP_000249348.1 | Type II secretion system protein E | VF |
| AAF13_RS00780 () | 157189..158412 | + | 1224 | WP_001173453.1 | Type II secretion system protein F | VF |
| AAF13_RS00785 () | 158429..158884 | + | 456 | WP_001087296.1 | Type II secretion system protein G | VF |
| AAF13_RS00790 () | 158888..159451 | + | 564 | WP_001115140.1 | Type II secretion system protein H | VF |
| AAF13_RS00795 () | 159448..159819 | + | 372 | WP_000820125.1 | Type II secretion system protein I | VF |
| AAF13_RS00800 () | 159816..160415 | + | 600 | WP_001255040.1 | Type II secretion system protein J | VF |
| AAF13_RS00805 () | 160418..161395 | + | 978 | WP_000633238.1 | Putative type II secretion system protein K | VF |
| AAF13_RS00810 () | 161392..162570 | + | 1179 | WP_000094962.1 | Type II secretion system protein L | VF |
| AAF13_RS00815 () | 162572..163108 | + | 537 | WP_000942795.1 | Type II secretion system protein M | VF |
| AAF13_RS00820 () | 163389..164231 | - | 843 | WP_001280493.1 | DUF4942 domain-containing protein | - |
| AAF13_RS31025 () | 164316..164513 | - | 198 | WP_085949090.1 | DUF957 domain-containing protein | - |
| AAF13_RS31030 () | 164541..164738 | - | 198 | Protein_156 | hypothetical protein | - |
| AAF13_RS00830 () | 164735..165112 | - | 378 | WP_001094429.1 | TA system toxin CbtA family protein | Toxin Detail |
| AAF13_RS00835 () | 165159..165536 | - | 378 | WP_001285616.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin Detail |
| AAF13_RS00840 () | 165616..165837 | - | 222 | WP_000692350.1 | DUF987 domain-containing protein | - |
| AAF13_RS00845 () | 165924..166400 | - | 477 | WP_001388380.1 | RadC family protein | - |
| AAF13_RS00850 () | 166416..166889 | - | 474 | WP_000855081.1 | antirestriction protein | - |
| AAF13_RS00855 () | 167191..168009 | - | 819 | WP_001234603.1 | DUF945 domain-containing protein | - |
| AAF13_RS00860 () | 168109..168342 | - | 234 | WP_001119729.1 | DUF905 family protein | - |
| AAF13_RS00865 () | 168421..168876 | - | 456 | WP_000581502.1 | hypothetical protein | - |
| AAF13_RS00870 () | 168952..171468 | - | 2517 | WP_001387066.1 | membrane protein | - |
| AAF13_RS00875 () | 171589..174708 | - | 3120 | WP_000820379.1 | autotransporter adhesin Ag43 | - |
| AAF13_RS00880 () | 175042..175914 | - | 873 | WP_001069724.1 | GTPase family protein | - |
| AAF13_RS00885 () | 176024..177043 | - | 1020 | WP_001388379.1 | hypothetical protein | - |
| AAF13_RS27865 () | 178222..178329 | - | 108 | Protein_169 | IS1 family transposase | - |
| AAF13_RS00895 () | 178538..179110 | - | 573 | WP_001170560.1 | hypothetical protein | - |
| AAF13_RS00900 () | 179196..179402 | - | 207 | WP_001095912.1 | AlpA family transcriptional regulator | - |
| AAF13_RS00905 () | 180101..180313 | + | 213 | WP_000453331.1 | hemolysin expression modulator Hha | - |
| AAF13_RS32195 () | 180553..180726 | - | 174 | WP_001387062.1 | hypothetical protein | - |
| AAF13_RS00910 () | 180930..181499 | + | 570 | WP_000220727.1 | inovirus Gp2 family protein | - |
| AAF13_RS32100 () | 181537..181695 | + | 159 | WP_000493525.1 | hypothetical protein | - |
| AAF13_RS00915 () | 181667..182050 | + | 384 | WP_000271022.1 | hypothetical protein | - |
| AAF13_RS00920 () | 182040..182459 | + | 420 | WP_001387059.1 | hypothetical protein | - |
| AAF13_RS00925 () | 182465..182647 | + | 183 | WP_001216313.1 | hypothetical protein | - |
| AAF13_RS00930 () | 182768..183391 | + | 624 | WP_001260266.1 | hypothetical protein | - |
| AAF13_RS00935 () | 183487..183720 | + | 234 | WP_000124181.1 | hypothetical protein | - |
| AAF13_RS00940 () | 183773..183964 | - | 192 | WP_001287796.1 | DUF4222 domain-containing protein | - |
| AAF13_RS00945 () | 184471..184968 | + | 498 | WP_000098939.1 | hypothetical protein | VF |
| AAF13_RS00950 () | 184990..186351 | + | 1362 | WP_000930193.1 | hypothetical protein | VF |
| AAF13_RS00955 () | 186453..187697 | + | 1245 | WP_000897032.1 | GIY-YIG nuclease family protein | - |
| AAF13_RS00960 () | 187933..189678 | + | 1746 | WP_001390303.1 | AAA family ATPase | - |
| AAF13_RS00965 () | 189743..190048 | + | 306 | WP_001420595.1 | hypothetical protein | - |
| AAF13_RS00970 () | 190163..190330 | + | 168 | Protein_187 | transcriptional regulator | - |
| AAF13_RS00975 () | 190409..190678 | + | 270 | WP_000226517.1 | PerC family transcriptional regulator | - |
| AAF13_RS00980 () | 190699..191343 | + | 645 | WP_001387055.1 | hypothetical protein | - |
| AAF13_RS00985 () | 191409..191732 | + | 324 | WP_001387054.1 | hypothetical protein | - |
| AAF13_RS00990 () | 191763..192342 | - | 580 | Protein_191 | transposase family protein | - |
| AAF13_RS01000 () | 192552..192938 | + | 387 | WP_014966195.1 | hypothetical protein | - |
| AAF13_RS27880 () | 192916..193041 | + | 126 | WP_001420591.1 | hypothetical protein | - |
| AAF13_RS27890 () | 193047..194063 | - | 1017 | Protein_194 | IS630 family transposase | - |
| AAF13_RS01010 () | 194459..194935 | + | 477 | WP_000072549.1 | hypothetical protein | VF |
| AAF13_RS01015 () | 194938..196416 | + | 1479 | WP_000215053.1 | hypothetical protein | VF |
| AAF13_RS01020 () | 196426..196932 | + | 507 | WP_000233190.1 | type VI secretion system protein AaiC/Hcp2 | - |
| AAF13_RS01025 () | 196942..197364 | + | 423 | WP_000555547.1 | hypothetical protein | - |
| AAF13_RS01030 () | 197357..199159 | + | 1803 | WP_001390300.1 | type VI secretion system baseplate subunit TssF | - |
| AAF13_RS01035 () | 199150..200082 | + | 933 | WP_001173975.1 | type VI secretion system baseplate subunit TssG | - |
| AAF13_RS01040 () | 200095..202077 | + | 1983 | WP_000198270.1 | type VI secretion system tip protein VgrG | - |
| AAF13_RS01045 () | 202088..202555 | + | 468 | WP_000005080.1 | hypothetical protein | - |
| AAF13_RS01050 () | 202565..202864 | + | 300 | WP_001390299.1 | PAAR domain-containing protein | - |
| AAF13_RS01055 () | 202868..203944 | + | 1077 | WP_001033155.1 | hypothetical protein | VF |
| AAF13_RS01060 () | 203952..204503 | + | 552 | WP_000152746.1 | type VI secretion lipoprotein TssJ | - |
| AAF13_RS01065 () | 204522..205934 | + | 1413 | WP_001154665.1 | type VI secretion system baseplate subunit TssK | - |
| AAF13_RS01075 () | 206273..206863 | + | 591 | WP_001028113.1 | hypothetical protein | VF |
| AAF13_RS01080 () | 206869..210273 | + | 3405 | WP_000914956.1 | type VI secretion protein | - |
| AAF13_RS01085 () | 210277..212826 | + | 2550 | WP_000029846.1 | Protein ClpV1 | VF |
| AAF13_RS30170 () | 213023..213760 | + | 738 | Protein_210 | IS3 family transposase IS1203 | Transposase |
| AAF13_RS01105 () | 214433..215941 | + | 1509 | WP_001189118.1 | group II intron reverse transcriptase/maturase | - |
| AAF13_RS01110 () | 216031..216504 | + | 474 | Protein_212 | IS3 family transposase IS629 | Transposase |
| AAF13_RS32200 () | 218262..218828 | + | 567 | WP_000587872.1 | hypothetical protein | - |
| AAF13_RS31050 () | 218893..219173 | + | 281 | Protein_214 | transposase | - |
| AAF13_RS01125 () | 219307..220461 | + | 1155 | WP_000359994.1 | type VI secretion system ImpA family N-terminal domain-containing protein | - |
| AAF13_RS30190 () | 221327..221497 | - | 171 | Protein_216 | ATP-dependent helicase | - |
| AAF13_RS01135 () | 221527..221715 | - | 189 | Protein_217 | IS66 family transposase IS682 | Transposase |
| AAF13_RS01140 () | 221776..222909 | + | 1134 | WP_000555380.1 | IS110 family transposase ISEc45 | Transposase |
| AAF13_RS27615 () | 222949..223311 | + | 363 | WP_077577697.1 | IS3 family transposase | - |
| AAF13_RS27925 () | 223315..223458 | + | 144 | Protein_220 | IS3 family transposase | - |
| AAF13_RS01150 () | 223644..225257 | - | 1614 | WP_000080172.1 | IS66-like element ISEc43 family transposase | - |
| AAF13_RS01155 () | 225288..225638 | - | 351 | WP_000624688.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| AAF13_RS01160 () | 225635..226069 | - | 435 | WP_001309734.1 | IS66 family insertion sequence hypothetical protein | - |
| AAF13_RS01165 () | 226157..226609 | + | 453 | Protein_224 | transposase | - |
| AAF13_RS01170 () | 226648..226890 | + | 243 | Protein_225 | IS256 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|