MGE detailed information
MGE type: Conjugative plasmid MGE length: 118061 bp
Accession: NZ_CP009115 Location: 1..118061 Organism: Klebsiella pneumoniae strain carbapenem-resistant blaNDM-1 Replicon: plasmid p2
Accession: NZ_CP009115 Location: 1..118061 Organism: Klebsiella pneumoniae strain carbapenem-resistant blaNDM-1 Replicon: plasmid p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FH42_RS26560 () | 249..581 | - | 333 | WP_004152339.1 | hypothetical protein | - |
| FH42_RS26565 () | 588..986 | - | 399 | WP_004171440.1 | hypothetical protein | - |
| FH42_RS26570 () | 1012..1341 | - | 330 | WP_004152337.1 | hypothetical protein | - |
| FH42_RS26575 () | 1369..1677 | - | 309 | WP_004152336.1 | hypothetical protein | - |
| FH42_RS29050 () | 2164..2623 | - | 460 | Protein_5 | hypothetical protein | - |
| FH42_RS26585 () | 2580..2810 | + | 231 | WP_001261282.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| FH42_RS26590 () | 2807..3223 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FH42_RS26595 () | 3297..4007 | + | 711 | WP_004152334.1 | ATP-binding protein | - |
| FH42_RS26605 () | 4041..4738 | + | 698 | Protein_9 | IS1 family transposase ISKpn14 | Transposase |
| FH42_RS26610 () | 4754..4864 | + | 111 | Protein_10 | mercuric transport protein periplasmic component | - |
| FH42_RS26615 () | 4900..5322 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| FH42_RS26620 () | 5374..7068 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| FH42_RS26625 () | 7086..7448 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| FH42_RS26630 () | 7445..7681 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| FH42_RS26635 () | 7717..8385 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| FH42_RS26640 () | 8460..9710 | + | 1251 | Protein_16 | transposase | - |
| FH42_RS26645 () | 9775..10146 | + | 372 | Protein_17 | IS6 family transposase IS15DII | Transposase |
| FH42_RS26650 () | 10296..11156 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| FH42_RS26655 () | 11339..11656 | - | 318 | Protein_19 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FH42_RS27920 () | 11856..12680 | - | 825 | WP_000722315.1 | Beta-lactamase OXA-18 | ARG |
| FH42_RS26665 () | 12740..13528 | - | 789 | WP_001206315.1 | Streptomycin 3''-adenylyltransferase | ARG |
| FH42_RS26670 () | 13598..14152 | - | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| FH42_RS26675 () | 14386..14943 | - | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| FH42_RS26680 () | 15107..15301 | + | 195 | Protein_24 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FH42_RS26685 () | 15507..16769 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| FH42_RS26690 () | 17025..17900 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| FH42_RS26695 () | 17947..18279 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| FH42_RS26700 () | 18293..21088 | + | 2796 | Protein_28 | Tn3 family transposase TnpA_Tn3 | Transposase |
| FH42_RS26705 () | 21131..22146 | - | 1016 | Protein_29 | IS3 family transposase ISEc36 | Transposase |
| FH42_RS26720 () | 22541..23197 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| FH42_RS26725 () | 23516..23944 | - | 429 | Protein_31 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| FH42_RS26730 () | 23977..25368 | - | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| FH42_RS26735 () | 25405..25977 | - | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| FH42_RS26740 () | 26114..26704 | - | 591 | WP_012477564.1 | plasmid pRiA4b ORF-3 family protein | - |
| FH42_RS29070 () | 26799..26969 | + | 171 | Protein_35 | transposase | - |
| FH42_RS26745 () | 27075..27854 | + | 780 | WP_014386410.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| FH42_RS29075 () | 28006..28941 | + | 936 | Protein_37 | IS30 family transposase ISAba125 | Transposase |
| FH42_RS26755 () | 29041..30072 | + | 1032 | WP_071905678.1 | IS630 family transposase ISSpu2 | Transposase |
| FH42_RS26760 () | 30287..31099 | + | 813 | WP_004201164.1 | Metallo-beta-lactamase type 2 | ARG |
| FH42_RS26765 () | 31103..31468 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| FH42_RS26770 () | 31473..32111 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| FH42_RS26775 () | 32122..33153 | - | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| FH42_RS26780 () | 33158..33487 | - | 330 | WP_004201171.1 | divalent-cation tolerance protein CutA | - |
| FH42_RS26785 () | 33551..34255 | + | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| FH42_RS30915 () | 34297..34407 | + | 111 | Protein_45 | Rpn family recombination-promoting nuclease/putative transposase | - |
| FH42_RS26790 () | 34404..35015 | - | 612 | WP_000176305.1 | DUF2913 family protein | - |
| FH42_RS26795 () | 35069..35350 | - | 282 | WP_001568067.1 | hypothetical protein | - |
| FH42_RS26800 () | 35523..35858 | + | 336 | WP_011977766.1 | C2H2-type zinc finger protein | - |
| FH42_RS26805 () | 36832..37845 | - | 1014 | WP_040120366.1 | replication initiation protein | - |
| FH42_RS29085 () | 38004..38081 | - | 78 | WP_071905679.1 | RepA leader peptide Tap | - |
| FH42_RS26810 () | 38313..38582 | - | 270 | WP_072198323.1 | replication regulatory protein RepA | - |
| FH42_RS26815 () | 38700..39179 | - | 480 | WP_014343478.1 | Phospholipase D | VF |
| FH42_RS26820 () | 39355..39663 | - | 309 | WP_040120367.1 | hypothetical protein | - |
| FH42_RS26825 () | 39660..40310 | - | 651 | WP_040120368.1 | DUF2726 domain-containing protein | - |
| FH42_RS26830 () | 40366..41010 | - | 645 | WP_004153014.1 | hypothetical protein | - |
| FH42_RS27925 () | 41060..41662 | - | 603 | WP_064750782.1 | hypothetical protein | - |
| FH42_RS26840 () | 41823..42416 | - | 594 | WP_004152380.1 | fertility inhibition protein FinO | - |
| FH42_RS26845 () | 42488..43213 | - | 726 | WP_040120370.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| FH42_RS26850 () | 43293..48554 | - | 5262 | WP_040120371.1 | Multifunctional conjugation protein TraI | Relaxase |
| FH42_RS26855 () | 48554..50866 | - | 2313 | Protein_60 | type IV conjugative transfer system coupling protein TraD | - |
| FH42_RS30920 () | 50995..51684 | - | 690 | WP_072198322.1 | hypothetical protein | - |
| FH42_RS26865 () | 51877..52608 | - | 732 | WP_004152629.1 | complement resistance protein TraT | - |
| FH42_RS26870 () | 52797..53324 | - | 528 | WP_040120388.1 | conjugal transfer protein TraS | - |
| FH42_RS26875 () | 53330..56179 | - | 2850 | WP_040120373.1 | conjugal transfer mating pair stabilization protein TraG | - |
| FH42_RS26880 () | 56179..57558 | - | 1380 | WP_072198320.1 | conjugal transfer protein TraH | - |
| FH42_RS26885 () | 57536..57979 | - | 444 | WP_014343488.1 | F-type conjugal transfer protein TrbF | - |
| FH42_RS26890 () | 58025..58582 | - | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FH42_RS26895 () | 58554..58793 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FH42_RS26900 () | 58804..59556 | - | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FH42_RS26905 () | 59577..59903 | - | 327 | WP_004144402.1 | hypothetical protein | - |
| FH42_RS26910 () | 59916..60164 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| FH42_RS26915 () | 60142..60396 | - | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| FH42_RS26920 () | 60428..62383 | - | 1956 | WP_040120375.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FH42_RS26925 () | 62442..63080 | - | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FH42_RS26930 () | 63093..64082 | - | 990 | WP_029497420.1 | conjugal transfer pilus assembly protein TraU | - |
| FH42_RS26935 () | 64079..64480 | - | 402 | WP_040120376.1 | hypothetical protein | - |
| FH42_RS26940 () | 64515..65150 | - | 636 | WP_029497419.1 | type-F conjugative transfer system protein TraW | - |
| FH42_RS26945 () | 65150..65539 | - | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| FH42_RS26950 () | 65539..68178 | - | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| FH42_RS26955 () | 68250..68648 | - | 399 | WP_023179972.1 | hypothetical protein | - |
| FH42_RS31150 () | 68656..68943 | - | 288 | Protein_81 | hypothetical protein | - |
| FH42_RS26965 () | 69025..69429 | - | 405 | WP_004197817.1 | hypothetical protein | - |
| FH42_RS26970 () | 69496..69807 | - | 312 | WP_029497417.1 | hypothetical protein | - |
| FH42_RS26975 () | 69808..70026 | - | 219 | WP_004195468.1 | hypothetical protein | - |
| FH42_RS26980 () | 70349..70933 | - | 585 | WP_040120377.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FH42_RS26985 () | 71005..72429 | - | 1425 | WP_040120378.1 | conjugal transfer protein TraB | - |
| FH42_RS26990 () | 72429..73169 | - | 741 | WP_040120379.1 | type-F conjugative transfer system secretin TraK | - |
| FH42_RS26995 () | 73156..73722 | - | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| FH42_RS27000 () | 73742..74047 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| FH42_RS27005 () | 74061..74429 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| FH42_RS27010 () | 74497..74697 | - | 201 | WP_046664192.1 | TraY domain-containing protein | - |
| FH42_RS27015 () | 74783..75484 | - | 702 | WP_040120380.1 | hypothetical protein | - |
| FH42_RS27020 () | 75714..76106 | - | 393 | WP_004194114.1 | relaxosome protein TraM | - |
| FH42_RS27025 () | 76538..77023 | + | 486 | WP_001568108.1 | hypothetical protein | VF |
| FH42_RS29095 () | 77056..77385 | - | 330 | WP_011977736.1 | hypothetical protein | - |
| FH42_RS27030 () | 77418..78239 | - | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| FH42_RS27035 () | 79056..79889 | - | 834 | WP_032445769.1 | N-6 DNA methylase | - |
| FH42_RS27040 () | 79940..80086 | - | 147 | WP_004152750.1 | hypothetical protein | - |
| FH42_RS27045 () | 80181..80528 | - | 348 | WP_032445771.1 | hypothetical protein | - |
| FH42_RS27050 () | 80595..80975 | - | 381 | WP_020802391.1 | hypothetical protein | - |
| FH42_RS27060 () | 81693..82106 | - | 414 | WP_040120381.1 | helix-turn-helix domain-containing protein | - |
| FH42_RS27065 () | 82107..82385 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| FH42_RS27070 () | 82375..82695 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FH42_RS27075 () | 82776..83000 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| FH42_RS27080 () | 83011..83223 | - | 213 | WP_032445756.1 | hypothetical protein | - |
| FH42_RS27085 () | 83284..83640 | - | 357 | WP_019706019.1 | hypothetical protein | - |
| FH42_RS27090 () | 84481..84798 | - | 318 | WP_032445789.1 | hypothetical protein | - |
| FH42_RS27095 () | 84813..85163 | - | 351 | WP_032445787.1 | hypothetical protein | - |
| FH42_RS27100 () | 85160..85432 | - | 273 | WP_032445785.1 | hypothetical protein | - |
| FH42_RS27105 () | 86131..86289 | - | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| FH42_RS27120 () | 87964..88338 | - | 375 | WP_040120382.1 | hypothetical protein | - |
| FH42_RS27125 () | 88394..88720 | - | 327 | WP_001568059.1 | hypothetical protein | - |
| FH42_RS27130 () | 88717..89445 | - | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| FH42_RS27135 () | 89442..89873 | - | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| FH42_RS27140 () | 89918..91975 | - | 2058 | WP_040120383.1 | ParB/RepB/Spo0J family partition protein | - |
| FH42_RS27145 () | 92045..92293 | - | 249 | WP_032445658.1 | DUF905 domain-containing protein | - |
| FH42_RS27150 () | 92342..92884 | - | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| FH42_RS27160 () | 93680..93997 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| FH42_RS27165 () | 94032..94286 | - | 255 | WP_032445741.1 | hypothetical protein | - |
| FH42_RS27170 () | 94474..94665 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| FH42_RS27175 () | 94708..95214 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| FH42_RS31155 () | 95257..95685 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| FH42_RS27190 () | 96318..97085 | - | 768 | WP_032445745.1 | hypothetical protein | - |
| FH42_RS27195 () | 97139..97558 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| FH42_RS27200 () | 97568..97789 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| FH42_RS27205 () | 97789..98490 | - | 702 | WP_001568041.1 | DNA methylase | - |
| FH42_RS27210 () | 98927..99157 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| FH42_RS27215 () | 99218..99889 | - | 672 | WP_004152354.1 | plasmid partitioning/stability family protein | - |
| FH42_RS27220 () | 99892..100863 | - | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| FH42_RS27225 () | 101095..101526 | + | 432 | WP_004152352.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| FH42_RS27230 () | 101526..102797 | + | 1272 | WP_004152351.1 | Y-family DNA polymerase | - |
| FH42_RS27235 () | 103198..104094 | + | 897 | WP_004152350.1 | RepB family plasmid replication initiator protein | - |
| FH42_RS27240 () | 104416..105621 | + | 1206 | WP_004152349.1 | Plasmid partition protein A | VF |
| FH42_RS27245 () | 105618..106592 | + | 975 | WP_004152348.1 | ParB/RepB/Spo0J family partition protein | - |
| FH42_RS27250 () | 106969..107301 | + | 333 | WP_004152347.1 | hypothetical protein | - |
| FH42_RS27255 () | 107526..107741 | + | 216 | WP_004227314.1 | hypothetical protein | - |
| FH42_RS27260 () | 107853..109880 | + | 2028 | WP_004152345.1 | type I restriction-modification system subunit M | - |
| FH42_RS27265 () | 109877..111193 | + | 1317 | WP_004152344.1 | restriction endonuclease subunit S | - |
| FH42_RS27270 () | 111194..114451 | + | 3258 | WP_004152343.1 | type I restriction endonuclease subunit R | - |
| FH42_RS27275 () | 114456..115724 | + | 1269 | WP_004152342.1 | ISL3 family transposase ISKpn25 | Transposase |
| FH42_RS29150 () | 115844..116317 | + | 474 | WP_004152341.1 | YkgJ family cysteine cluster protein | - |
| FH42_RS29155 () | 116409..116639 | + | 231 | WP_011977773.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|