MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 141341 bp
Accession: NZ_CP007634 Location: 78146..219486 Organism: Vibrio cholerae strain 2012EL-2176 Replicon: chromosome
Accession: NZ_CP007634 Location: 78146..219486 Organism: Vibrio cholerae strain 2012EL-2176 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EN18_RS00295 () | 73166..73573 | + | 408 | WP_000887847.1 | MarR family transcriptional regulator | - |
| EN18_RS00300 () | 73620..74957 | + | 1338 | WP_000981941.1 | sodium-coupled multidrug efflux MATE transporter VcrM | - |
| EN18_RS00305 () | 75010..75888 | - | 879 | WP_000872504.1 | U32 family peptidase | - |
| EN18_RS00310 () | 75900..76913 | - | 1014 | WP_000421327.1 | U32 family peptidase | - |
| EN18_RS00315 () | 77021..79075 | - | 2055 | WP_001111411.1 | bifunctional diguanylate cyclase/phosphodiesterase | - |
| EN18_RS00320 () | 79308..79835 | + | 528 | WP_000932672.1 | SCP2 domain-containing protein | - |
| EN18_RS00325 () | 79819..80322 | + | 504 | WP_000908540.1 | N-acetyltransferase | - |
| EN18_RS00330 () | 80433..80840 | + | 408 | WP_000953212.1 | DNA polymerase III subunit psi | - |
| EN18_RS00335 () | 80837..81286 | + | 450 | WP_000214238.1 | Ribosomal-protein-alanine acetyltransferase | VF |
| EN18_RS00340 () | 81275..83332 | - | 2058 | WP_000160066.1 | putative signaling protein | VF |
| EN18_RS00345 () | 84073..84261 | + | 189 | WP_000127615.1 | hypothetical protein | - |
| EN18_RS00350 () | 84407..86425 | + | 2019 | WP_000211147.1 | ATP-binding protein | - |
| EN18_RS00355 () | 86555..87796 | - | 1242 | WP_001218618.1 | Prophage integrase IntS ; Integrase | Integrase |
| EN18_RS00360 () | 87798..88067 | - | 270 | WP_001995600.1 | hypothetical protein | - |
| EN18_RS00365 () | 88070..89044 | - | 975 | WP_000497807.1 | ParM/StbA family protein | - |
| EN18_RS00370 () | 89509..89952 | + | 444 | WP_000348524.1 | hypothetical protein | - |
| EN18_RS00375 () | 89963..91006 | - | 1044 | Protein_69 | translesion error-prone DNA polymerase V subunit UmuC | - |
| EN18_RS00380 () | 91410..91988 | + | 579 | Protein_70 | Tn3 family transposase TnpA_IS3000 | Transposase |
| EN18_RS00385 () | 92126..95104 | + | 2979 | WP_000985631.1 | Tn3 family transposase TnpA_ISShfr9 | Transposase |
| EN18_RS21465 () | 95219..95410 | + | 192 | Protein_72 | hypothetical protein | - |
| EN18_RS00395 () | 95522..97015 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| EN18_RS21470 () | 97484..97930 | + | 447 | Protein_74 | DUF3363 domain-containing protein | - |
| EN18_RS00405 () | 98147..99361 | + | 1215 | WP_000214119.1 | Bicyclomycin resistance protein | ARG |
| EN18_RS00410 () | 99389..99694 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| EN18_RS00415 () | 99806..100210 | + | 405 | Protein_77 | IS91 family transposase ISPps1 | Transposase |
| EN18_RS00420 () | 100317..101153 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| EN18_RS00425 () | 101153..101956 | - | 804 | WP_001082316.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| EN18_RS00430 () | 102017..102832 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| EN18_RS00435 () | 103303..106281 | + | 2979 | WP_000985631.1 | Tn3 family transposase TnpA_ISShfr9 | Transposase |
| EN18_RS21475 () | 106396..106587 | + | 192 | Protein_82 | hypothetical protein | - |
| EN18_RS00445 () | 106699..108192 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| EN18_RS21480 () | 108661..109107 | + | 447 | Protein_84 | DUF3363 domain-containing protein | - |
| EN18_RS00455 () | 109324..110538 | + | 1215 | WP_000214119.1 | Bicyclomycin resistance protein | ARG |
| EN18_RS00460 () | 110566..110871 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| EN18_RS00465 () | 110983..111387 | + | 405 | Protein_87 | IS91 family transposase ISPps1 | Transposase |
| EN18_RS00470 () | 111494..112330 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| EN18_RS00475 () | 112330..113133 | - | 804 | WP_001082316.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| EN18_RS00480 () | 113194..114009 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| EN18_RS00485 () | 114480..115787 | + | 1308 | Protein_91 | Tn3 family transposase TnpA_ISShfr9 | Transposase |
| EN18_RS00490 () | 115824..117035 | - | 1212 | WP_001122813.1 | IS256 family transposase ISSod18 | Transposase |
| EN18_RS00495 () | 117090..118595 | + | 1506 | Protein_93 | BREX system Lon protease-like protein BrxL | - |
| EN18_RS00500 () | 118622..119392 | + | 771 | WP_000158025.1 | hypothetical protein | - |
| EN18_RS00505 () | 119427..120242 | + | 816 | WP_001125250.1 | abortive infection family protein | - |
| EN18_RS00510 () | 120364..122514 | + | 2151 | WP_000475916.1 | TraI domain-containing protein | - |
| EN18_RS00515 () | 122563..124383 | + | 1821 | WP_000661888.1 | conjugative transfer system coupling protein TraD | - |
| EN18_RS00520 () | 124393..124953 | + | 561 | WP_000546514.1 | hypothetical protein | - |
| EN18_RS00525 () | 124940..125575 | + | 636 | WP_000033757.1 | DUF4400 domain-containing protein | - |
| EN18_RS00530 () | 125602..126189 | - | 588 | WP_001167482.1 | hypothetical protein | - |
| EN18_RS00540 () | 126478..126759 | + | 282 | WP_000433891.1 | type IV conjugative transfer system protein TraL | - |
| EN18_RS00545 () | 126756..127382 | + | 627 | WP_000667170.1 | hypothetical protein | - |
| EN18_RS00550 () | 127366..128262 | + | 897 | WP_001911237.1 | type-F conjugative transfer system secretin TraK | - |
| EN18_RS00555 () | 128265..129554 | + | 1290 | WP_000647305.1 | TraB/VirB10 family protein | - |
| EN18_RS00560 () | 129629..130201 | + | 573 | WP_001944091.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EN18_RS00565 () | 130198..130584 | + | 387 | WP_000180223.1 | hypothetical protein | - |
| EN18_RS00570 () | 130805..131596 | + | 792 | WP_000095578.1 | type IV toxin-antitoxin system AbiEi family antitoxin | Antitoxin Detail |
| EN18_RS00575 () | 131589..132527 | + | 939 | WP_000356587.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin Detail |
| EN18_RS00580 () | 132659..133351 | + | 693 | WP_001228926.1 | DsbC family protein | - |
| EN18_RS00585 () | 133351..135750 | + | 2400 | WP_000648042.1 | type IV secretion system protein TraC | - |
| EN18_RS00590 () | 135743..136090 | + | 348 | WP_001044650.1 | hypothetical protein | - |
| EN18_RS00595 () | 136074..136586 | + | 513 | WP_001166558.1 | S26 family signal peptidase | - |
| EN18_RS00600 () | 136597..137721 | + | 1125 | WP_001189235.1 | hypothetical protein | - |
| EN18_RS00605 () | 137705..138733 | + | 1029 | WP_000735886.1 | TraU family protein | - |
| EN18_RS00610 () | 138736..142428 | + | 3693 | WP_000805082.1 | conjugal transfer protein TraN | - |
| EN18_RS00615 () | 142519..144084 | - | 1566 | WP_001918292.1 | hypothetical protein | - |
| EN18_RS00620 () | 144215..144970 | - | 756 | WP_000546748.1 | IS21 family transposase ISAlde2 | Transposase |
| EN18_RS00625 () | 144960..146459 | - | 1500 | WP_001920874.1 | IS21 family transposase ISCte8 | Transposase |
| EN18_RS00630 () | 146567..147583 | - | 1017 | WP_001918293.1 | ATP-binding protein | - |
| EN18_RS00635 () | 147814..148497 | - | 684 | WP_001082313.1 | endonuclease | - |
| EN18_RS00640 () | 148606..149208 | - | 603 | WP_000035785.1 | hypothetical protein | - |
| EN18_RS00645 () | 149576..149902 | + | 327 | WP_000455723.1 | hypothetical protein | - |
| EN18_RS00650 () | 149918..150337 | + | 420 | WP_000795985.1 | single-stranded DNA-binding protein | - |
| EN18_RS00655 () | 150417..151235 | + | 819 | WP_000414662.1 | phage recombination protein Bet | - |
| EN18_RS21485 () | 151317..151460 | + | 144 | WP_000167277.1 | hypothetical protein | - |
| EN18_RS00660 () | 151521..152537 | + | 1017 | WP_000862956.1 | YqaJ viral recombinase family protein | - |
| EN18_RS00665 () | 152747..153706 | + | 960 | WP_000139695.1 | CbbQ/NirQ/NorQ C-terminal domain-containing protein | - |
| EN18_RS00670 () | 153706..154473 | + | 768 | WP_000970189.1 | hypothetical protein | - |
| EN18_RS00675 () | 154572..155525 | + | 954 | WP_000027441.1 | DUF3150 domain-containing protein | - |
| EN18_RS00680 () | 155587..156027 | + | 441 | WP_001192023.1 | hypothetical protein | - |
| EN18_RS00685 () | 156097..157752 | + | 1656 | WP_001016320.1 | VWA domain-containing protein | - |
| EN18_RS00690 () | 157837..158334 | + | 498 | WP_000797297.1 | DNA repair protein RadC | - |
| EN18_RS00695 () | 158334..158675 | + | 342 | WP_001081787.1 | hypothetical protein | - |
| EN18_RS00700 () | 158766..159839 | + | 1074 | WP_001207590.1 | toprim domain-containing protein | - |
| EN18_RS00705 () | 159929..160636 | + | 708 | WP_000989526.1 | hypothetical protein | - |
| EN18_RS20115 () | 160908..161312 | + | 405 | WP_000023761.1 | VOC family protein | - |
| EN18_RS00715 () | 161309..162010 | - | 702 | WP_001901434.1 | helix-turn-helix transcriptional regulator | - |
| EN18_RS00720 () | 162110..162406 | - | 297 | WP_001919795.1 | DUF1801 domain-containing protein | - |
| EN18_RS00725 () | 162543..162953 | - | 411 | WP_000592337.1 | helix-turn-helix transcriptional regulator | - |
| EN18_RS00730 () | 163151..163546 | - | 396 | WP_000096366.1 | hypothetical protein | - |
| EN18_RS00735 () | 163681..164154 | - | 474 | WP_000777554.1 | Dihydrofolate reductase type 1 | ARG |
| EN18_RS00740 () | 164442..165401 | + | 960 | WP_000198593.1 | Tyrosine recombinase XerD ; Integrase | Integrase |
| EN18_RS00745 () | 165658..166602 | + | 945 | WP_001260107.1 | thioredoxin family protein | - |
| EN18_RS00750 () | 166605..167993 | + | 1389 | WP_000755289.1 | conjugal transfer protein TraH | - |
| EN18_RS00755 () | 167997..171566 | + | 3570 | WP_000263683.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| EN18_RS00760 () | 171599..172030 | - | 432 | WP_000183214.1 | hypothetical protein | - |
| EN18_RS00765 () | 172088..172621 | - | 534 | WP_000566755.1 | hypothetical protein | - |
| EN18_RS00770 () | 172618..172917 | - | 300 | WP_000210564.1 | flagellar transcriptional regulator FlhD | - |
| EN18_RS00775 () | 172914..173462 | - | 549 | WP_000848909.1 | lytic transglycosylase domain-containing protein | - |
| EN18_RS00780 () | 173449..174057 | - | 609 | WP_001918295.1 | hypothetical protein | - |
| EN18_RS00785 () | 174098..174967 | - | 870 | WP_001205850.1 | hypothetical protein | - |
| EN18_RS00790 () | 175023..175274 | - | 252 | WP_000451746.1 | helix-turn-helix domain-containing protein | - |
| EN18_RS00795 () | 175392..176039 | + | 648 | WP_000854920.1 | LexA family transcriptional regulator | - |
| EN18_RS00800 () | 176296..177885 | + | 1590 | WP_000013192.1 | peptide chain release factor 3 | - |
| EN18_RS00805 () | 178007..179278 | - | 1272 | WP_000597951.1 | ATP-dependent RNA helicase SrmB | - |
| EN18_RS00810 () | 179366..180088 | - | 723 | WP_000856169.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| EN18_RS00815 () | 180397..181710 | + | 1314 | WP_000815019.1 | branched-chain amino acid transport system II carrier protein | - |
| EN18_RS00820 () | 181880..182978 | + | 1099 | WP_010895430.1 | peptide chain release factor 2 | - |
| EN18_RS00825 () | 183009..184541 | + | 1533 | WP_000128764.1 | lysine--tRNA ligase | - |
| EN18_RS00830 () | 184815..186149 | + | 1335 | WP_000107102.1 | Transcriptional regulatory protein ZraR | VF |
| EN18_RS00835 () | 186727..186978 | + | 252 | WP_001249919.1 | hypothetical protein | - |
| EN18_RS00840 () | 187016..188050 | - | 1035 | WP_001200442.1 | NADP(H)-dependent aldo-keto reductase | - |
| EN18_RS00845 () | 188267..188932 | - | 666 | WP_000801223.1 | DNA mismatch repair endonuclease MutH | - |
| EN18_RS00855 () | 189563..190081 | + | 519 | WP_001911254.1 | RNA pyrophosphohydrolase | - |
| EN18_RS00860 () | 190084..192330 | + | 2247 | WP_000952226.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| EN18_RS00865 () | 192340..193134 | + | 795 | WP_001019422.1 | sulfite exporter TauE/SafE family protein | - |
| EN18_RS00870 () | 193163..193978 | + | 816 | WP_001135560.1 | prolipoprotein diacylglyceryl transferase | - |
| EN18_RS00875 () | 193988..194839 | + | 852 | WP_001250353.1 | thymidylate synthase | - |
| EN18_RS00880 () | 194932..196080 | - | 1149 | WP_000609761.1 | Na/Pi cotransporter family protein | - |
| EN18_RS00885 () | 196475..197365 | + | 891 | WP_000018876.1 | Transcriptional activator protein NhaR | VF |
| EN18_RS00890 () | 197588..197890 | + | 303 | WP_001053149.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EN18_RS00895 () | 197959..198219 | - | 261 | WP_000002742.1 | 30S ribosomal protein S20 | - |
| EN18_RS00900 () | 198477..200039 | + | 1563 | WP_001911253.1 | murein biosynthesis integral membrane protein MurJ | - |
| EN18_RS00905 () | 200108..201076 | + | 969 | WP_000420406.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| EN18_RS00910 () | 201107..203956 | + | 2850 | WP_000006088.1 | isoleucine--tRNA ligase | - |
| EN18_RS00915 () | 203972..204487 | + | 516 | WP_000071968.1 | Lipoprotein signal peptidase | VF |
| EN18_RS00920 () | 204650..205084 | + | 435 | WP_001068088.1 | FKBP-type peptidyl-prolyl cis-trans isomerase | - |
| EN18_RS00925 () | 205119..206081 | + | 963 | WP_001883831.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | - |
| EN18_RS00930 () | 206218..207702 | - | 1485 | WP_000964317.1 | carbon starvation protein A | - |
| EN18_RS00935 () | 207955..208296 | + | 342 | WP_001883835.1 | DUF2799 domain-containing protein | - |
| EN18_RS00940 () | 208315..210111 | + | 1797 | WP_000544193.1 | sodium:proton antiporter | - |
| EN18_RS00945 () | 210135..211058 | - | 924 | WP_000180252.1 | N-acetylmuramic acid 6-phosphate etherase | - |
| EN18_RS00950 () | 211076..212188 | - | 1113 | WP_000840717.1 | anhydro-N-acetylmuramic acid kinase | - |
| EN18_RS00955 () | 212294..213286 | + | 993 | WP_000529115.1 | beta-N-acetylhexosaminidase | - |
| EN18_RS00960 () | 213313..214026 | - | 714 | WP_000947378.1 | Transcriptional regulatory protein BtsR | VF |
| EN18_RS00965 () | 214036..215712 | - | 1677 | WP_000364257.1 | Sensor histidine kinase BtsS | VF |
| EN18_RS00970 () | 215954..217027 | + | 1074 | WP_000747937.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| EN18_RS00975 () | 217040..218167 | + | 1128 | WP_000257629.1 | T-protein | VF |
| EN18_RS00980 () | 218234..218605 | - | 372 | WP_000570783.1 | PilZ domain-containing protein | - |
| EN18_RS00985 () | 218776..220443 | - | 1668 | WP_000852865.1 | energy-dependent translational throttle protein EttA | - |
| EN18_RS00990 () | 220805..222751 | + | 1947 | WP_000197615.1 | murein transglycosylase | - |
| EN18_RS00995 () | 222806..223117 | + | 312 | WP_000250616.1 | trp operon repressor | - |
| EN18_RS01000 () | 223195..223719 | - | 525 | WP_001226222.1 | inosine/xanthosine triphosphatase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|