MGE detailed information
MGE type: Conjugative plasmid MGE length: 123767 bp
Accession: NZ_AP024782 Location: 1..123767 Organism: Klebsiella pneumoniae strain TUM12136 Replicon: plasmid IncN-R
Accession: NZ_AP024782 Location: 1..123767 Organism: Klebsiella pneumoniae strain TUM12136 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J90_RS26380 (TUM12136_50760) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J90_RS26385 (TUM12136_50770) | 2219..2518 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J90_RS26390 (TUM12136_50780) | 2590..5241 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J90_RS27365 (TUM12136_50800) | 5660..5926 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J90_RS26395 | 5858..6543 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J90_RS26400 (TUM12136_50820) | 7216..8724 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J90_RS26405 | 8805..8984 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J90_RS26410 (TUM12136_50830) | 9266..10342 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J90_RS26415 | 10359..10635 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J90_RS26420 | 10750..10926 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J90_RS26425 (TUM12136_50840) | 10941..11777 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J90_RS26430 (TUM12136_50850) | 11842..12240 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J90_RS26435 (TUM12136_50860) | 12284..13393 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J90_RS26440 (TUM12136_50870) | 13428..13703 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J90_RS26450 (TUM12136_50900) | 15125..15694 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J90_RS26455 (TUM12136_50910) | 15934..17148 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J90_RS26460 (TUM12136_50920) | 17182..18615 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J90_RS26465 (TUM12136_50930) | 18714..18986 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J90_RS26470 (TUM12136_50940) | 18997..19203 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J90_RS26475 (TUM12136_50950) | 19208..19849 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J90_RS26480 (TUM12136_50960) | 19905..20216 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J90_RS26485 (TUM12136_50970) | 20252..20566 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J90_RS26490 (TUM12136_50980) | 20563..20907 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J90_RS26495 (TUM12136_50990) | 20923..21228 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J90_RS26500 (TUM12136_51000) | 21337..22074 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J90_RS26505 (TUM12136_51010) | 22083..22364 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J90_RS26510 (TUM12136_51020) | 22374..22667 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J90_RS26515 (TUM12136_51030) | 22717..23034 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J90_RS26520 (TUM12136_51040) | 23034..25634 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J90_RS26525 (TUM12136_51050) | 25652..26365 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J90_RS26530 (TUM12136_51060) | 26373..26600 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J90_RS26535 (TUM12136_51070) | 26616..27656 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J90_RS26540 (TUM12136_51080) | 27875..28573 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J90_RS26545 (TUM12136_51090) | 28584..29468 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J90_RS26550 (TUM12136_51100) | 29468..30628 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J90_RS26555 (TUM12136_51110) | 30670..31665 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J90_RS26560 (TUM12136_51120) | 31665..31931 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J90_RS26565 (TUM12136_51130) | 32137..32268 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J90_RS26570 (TUM12136_51140) | 32325..33317 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J90_RS26575 | 33366..33521 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J90_RS26580 (TUM12136_51150) | 33816..35531 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J90_RS26585 (TUM12136_51160) | 35641..38670 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J90_RS26590 (TUM12136_51170) | 38777..39802 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J90_RS26595 (TUM12136_51180) | 39799..40578 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J90_RS26600 (TUM12136_51190) | 40866..41747 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J90_RS26605 (TUM12136_51200) | 41997..43316 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J90_RS26610 (TUM12136_51210) | 43593..44777 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J90_RS26615 (TUM12136_51220) | 44879..45109 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J90_RS26620 (TUM12136_51230) | 45281..45640 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J90_RS26625 | 46297..46707 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J90_RS26630 (TUM12136_51240) | 46806..47426 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J90_RS26635 (TUM12136_51250) | 47515..50412 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J90_RS26640 (TUM12136_51260) | 50485..51187 | + | 703 | Protein_53 | IS6 family transposase IS26 | Transposase |
| K6J90_RS26645 | 51237..51347 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J90_RS26650 | 51407..52229 | + | 823 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J90_RS26655 | 52429..52747 | + | 319 | Protein_56 | recombinase family protein | - |
| K6J90_RS26660 (TUM12136_51280) | 52930..53789 | + | 860 | Protein_57 | Beta-lactamase TEM | ARG |
| K6J90_RS26665 (TUM12136_51300) | 53979..54314 | - | 336 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6J90_RS26670 (TUM12136_51310) | 54379..55629 | - | 1251 | Protein_59 | transposase | - |
| K6J90_RS26675 (TUM12136_51320) | 55704..56372 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J90_RS26680 (TUM12136_51330) | 56408..56644 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J90_RS26685 (TUM12136_51340) | 56641..57003 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J90_RS26690 (TUM12136_51350) | 57021..58715 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J90_RS26695 (TUM12136_51360) | 58767..59189 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J90_RS26700 | 59225..59335 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J90_RS26710 (TUM12136_51390) | 60103..60792 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J90_RS26715 (TUM12136_51400) | 60866..61282 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J90_RS26720 (TUM12136_51410) | 61279..61509 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J90_RS26725 | 61466..61927 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J90_RS26730 (TUM12136_51420) | 62071..62421 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J90_RS26735 (TUM12136_51430) | 62472..63215 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J90_RS26740 (TUM12136_51440) | 63212..63988 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J90_RS27370 (TUM12136_51450) | 64046..64225 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J90_RS26745 (TUM12136_51460) | 64260..67265 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J90_RS26750 (TUM12136_51480) | 67427..67984 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J90_RS26755 (TUM12136_51490) | 68218..68772 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J90_RS26760 (TUM12136_51500) | 68842..69057 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J90_RS26765 (TUM12136_51510) | 69123..69827 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J90_RS26770 (TUM12136_51520) | 69882..70052 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J90_RS27375 (TUM12136_51530) | 70183..70281 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J90_RS26775 | 70410..70514 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J90_RS26780 (TUM12136_51540) | 71044..71910 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J90_RS26785 (TUM12136_51550) | 72087..72356 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J90_RS26790 (TUM12136_51560) | 72771..73976 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J90_RS26795 (TUM12136_51570) | 73976..74950 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J90_RS26800 (TUM12136_51580) | 75032..76303 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J90_RS26805 (TUM12136_51590) | 76303..76734 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J90_RS26810 (TUM12136_51610) | 77140..78626 | + | 1487 | Protein_89 | group II intron reverse transcriptase/maturase | - |
| K6J90_RS26815 | 78777..79472 | + | 696 | Protein_90 | IS1 family transposase IS1X3 | Transposase |
| K6J90_RS26820 | 79482..79790 | + | 309 | Protein_91 | replication initiation protein | - |
| K6J90_RS26825 (TUM12136_51640) | 81192..82160 | + | 969 | WP_030005799.1 | IS5 family transposase IS903B | Transposase |
| K6J90_RS27380 (TUM12136_51650) | 82300..82684 | - | 385 | Protein_93 | plasmid stabilization protein StbA | - |
| K6J90_RS26835 (TUM12136_51660) | 83266..83499 | + | 234 | Protein_94 | transposase | - |
| K6J90_RS26840 (TUM12136_51670) | 83532..86498 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J90_RS26845 (TUM12136_51680) | 86502..87062 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J90_RS26850 (TUM12136_51690) | 87238..87588 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J90_RS26855 (TUM12136_51710) | 87791..88804 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J90_RS26860 (TUM12136_51720) | 88971..89813 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J90_RS26865 (TUM12136_51730) | 89909..90517 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J90_RS26870 (TUM12136_51740) | 90575..91413 | + | 839 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J90_RS26875 | 91628..92887 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J90_RS26880 (TUM12136_51760) | 92980..93818 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J90_RS26885 (TUM12136_51770) | 93941..94273 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J90_RS26890 (TUM12136_51780) | 94520..95152 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J90_RS26895 (TUM12136_51790) | 95467..96447 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J90_RS26900 (TUM12136_51800) | 96553..97257 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J90_RS26905 (TUM12136_51810) | 97371..98147 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J90_RS26910 (TUM12136_51830) | 98376..99401 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J90_RS26915 | 99476..99763 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6J90_RS26920 (TUM12136_51840) | 99823..100575 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J90_RS26925 (TUM12136_51850) | 100637..101518 | + | 882 | Protein_112 | Tn3 family transposase | - |
| K6J90_RS26930 | 101681..101764 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6J90_RS26935 (TUM12136_51860) | 102631..102906 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6J90_RS26940 (TUM12136_51870) | 103079..103393 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J90_RS26945 (TUM12136_51880) | 103648..104004 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J90_RS26950 (TUM12136_51890) | 103994..104395 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J90_RS26955 (TUM12136_51900) | 104392..104682 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J90_RS26960 (TUM12136_51910) | 104746..105144 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J90_RS26965 (TUM12136_51920) | 105144..108380 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J90_RS26970 (TUM12136_51930) | 108380..109909 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J90_RS26975 (TUM12136_51940) | 109911..110327 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J90_RS26980 (TUM12136_51950) | 110884..111270 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J90_RS26985 (TUM12136_51960) | 111279..111995 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J90_RS26990 (TUM12136_51970) | 111997..112365 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6J90_RS26995 (TUM12136_51980) | 112566..112910 | + | 345 | WP_012561137.1 | hypothetical protein | - |
| K6J90_RS27000 (TUM12136_51990) | 113372..113551 | - | 180 | WP_012561134.1 | protein CcgAI | - |
| K6J90_RS27005 (TUM12136_52000) | 114379..114888 | - | 510 | WP_012561131.1 | antirestriction protein ArdA | - |
| K6J90_RS27010 (TUM12136_52010) | 116237..116569 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6J90_RS27015 (TUM12136_52020) | 116779..117063 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6J90_RS27385 | 117132..117332 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6J90_RS27025 (TUM12136_52040) | 117488..117784 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J90_RS27030 (TUM12136_52060) | 118665..118904 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J90_RS27035 (TUM12136_52070) | 118914..119318 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J90_RS27040 (TUM12136_52080) | 119376..119801 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J90_RS27045 (TUM12136_52090) | 120217..120657 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J90_RS27050 (TUM12136_52100) | 120645..121910 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J90_RS27055 (TUM12136_52110) | 122061..122852 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J90_RS27060 (TUM12136_52120) | 122867..123208 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|