MGE detailed information
MGE type: Conjugative plasmid MGE length: 122441 bp
Accession: NZ_AP024779 Location: 1..122441 Organism: Klebsiella pneumoniae strain TUM12135 Replicon: plasmid IncN-R
Accession: NZ_AP024779 Location: 1..122441 Organism: Klebsiella pneumoniae strain TUM12135 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J93_RS25965 (TUM12135_49910) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J93_RS25970 (TUM12135_49920) | 2219..2518 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J93_RS25975 (TUM12135_49930) | 2590..5241 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J93_RS26935 (TUM12135_49950) | 5660..5926 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J93_RS25980 | 5858..6543 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J93_RS25985 (TUM12135_49970) | 7216..8724 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J93_RS25990 | 8805..8984 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J93_RS25995 (TUM12135_49980) | 9266..10342 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J93_RS26000 | 10359..10635 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J93_RS26005 | 10750..10926 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J93_RS26010 (TUM12135_49990) | 10941..11777 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J93_RS26015 (TUM12135_50000) | 11842..12240 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J93_RS26020 (TUM12135_50010) | 12284..13393 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J93_RS26025 (TUM12135_50020) | 13428..13703 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J93_RS26035 (TUM12135_50050) | 15125..15694 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J93_RS26040 (TUM12135_50060) | 15934..17148 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J93_RS26045 (TUM12135_50070) | 17182..18615 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J93_RS26050 (TUM12135_50080) | 18714..18986 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J93_RS26055 (TUM12135_50090) | 18997..19203 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J93_RS26060 (TUM12135_50100) | 19208..19849 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J93_RS26065 (TUM12135_50110) | 19905..20216 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J93_RS26070 (TUM12135_50120) | 20252..20566 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J93_RS26075 (TUM12135_50130) | 20563..20907 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J93_RS26080 (TUM12135_50140) | 20923..21228 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J93_RS26085 (TUM12135_50150) | 21337..22074 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J93_RS26090 (TUM12135_50160) | 22083..22364 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J93_RS26095 (TUM12135_50170) | 22374..22667 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J93_RS26100 (TUM12135_50180) | 22717..23034 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J93_RS26105 (TUM12135_50190) | 23034..25634 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J93_RS26110 (TUM12135_50200) | 25652..26365 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J93_RS26115 (TUM12135_50210) | 26373..26600 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J93_RS26120 (TUM12135_50220) | 26616..27656 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J93_RS26125 (TUM12135_50230) | 27875..28573 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J93_RS26130 (TUM12135_50240) | 28584..29468 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J93_RS26135 (TUM12135_50250) | 29468..30628 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J93_RS26140 (TUM12135_50260) | 30670..31665 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J93_RS26145 (TUM12135_50270) | 31665..31931 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J93_RS26150 (TUM12135_50280) | 32137..32268 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J93_RS26155 (TUM12135_50290) | 32325..33317 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J93_RS26160 | 33366..33521 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J93_RS26165 (TUM12135_50300) | 33816..35531 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J93_RS26170 (TUM12135_50310) | 35641..38670 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J93_RS26175 (TUM12135_50320) | 38777..39802 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J93_RS26180 (TUM12135_50330) | 39799..40578 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J93_RS26185 (TUM12135_50340) | 40866..41747 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J93_RS26190 (TUM12135_50350) | 41997..43316 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J93_RS26195 (TUM12135_50360) | 43593..44777 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J93_RS26200 (TUM12135_50370) | 44879..45109 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J93_RS26205 (TUM12135_50380) | 45281..45640 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J93_RS26210 | 46297..46707 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J93_RS26215 (TUM12135_50390) | 46806..47426 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J93_RS26220 (TUM12135_50400) | 47515..50412 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J93_RS26225 (TUM12135_50410) | 50485..51189 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J93_RS26230 | 51239..51349 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J93_RS26235 | 51409..52233 | + | 825 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J93_RS26240 (TUM12135_50440) | 52433..52750 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J93_RS26245 (TUM12135_50450) | 52933..53793 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6J93_RS26250 (TUM12135_50460) | 53943..54314 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6J93_RS26255 (TUM12135_50470) | 54379..55629 | - | 1251 | Protein_59 | transposase | - |
| K6J93_RS26260 (TUM12135_50480) | 55704..56372 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J93_RS26265 (TUM12135_50490) | 56408..56644 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J93_RS26270 (TUM12135_50500) | 56641..57003 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J93_RS26275 (TUM12135_50510) | 57021..58715 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J93_RS26280 (TUM12135_50520) | 58767..59189 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J93_RS26285 | 59225..59335 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J93_RS26295 (TUM12135_50550) | 60103..60792 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J93_RS26300 (TUM12135_50560) | 60866..61282 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J93_RS26305 (TUM12135_50570) | 61279..61509 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J93_RS26310 | 61466..61927 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J93_RS26315 (TUM12135_50580) | 62071..62421 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J93_RS26320 (TUM12135_50590) | 62472..63215 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J93_RS26325 (TUM12135_50600) | 63212..63988 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J93_RS26940 (TUM12135_50610) | 64046..64225 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J93_RS26330 (TUM12135_50620) | 64260..67265 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J93_RS26335 (TUM12135_50640) | 67427..67984 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J93_RS26340 (TUM12135_50650) | 68218..68772 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J93_RS26345 (TUM12135_50660) | 68842..69057 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J93_RS26350 (TUM12135_50670) | 69123..69827 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J93_RS26355 (TUM12135_50680) | 69882..70052 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J93_RS26945 (TUM12135_50690) | 70183..70281 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J93_RS26360 | 70410..70514 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J93_RS26365 (TUM12135_50700) | 71044..71910 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J93_RS26370 (TUM12135_50710) | 72087..72356 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J93_RS26375 (TUM12135_50720) | 72771..73976 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J93_RS26380 (TUM12135_50730) | 73976..74950 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J93_RS26385 (TUM12135_50740) | 75032..76303 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J93_RS26390 (TUM12135_50750) | 76303..76734 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J93_RS26395 (TUM12135_50760) | 77140..78627 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6J93_RS26400 | 78779..79476 | + | 698 | WP_223229472.1 | IS1 family transposase IS1X3 | Transposase |
| K6J93_RS26405 | 79486..79794 | + | 309 | Protein_91 | replication initiation protein | - |
| K6J93_RS26410 (TUM12135_50790) | 81197..82165 | + | 969 | WP_077259757.1 | IS5 family transposase IS903B | Transposase |
| K6J93_RS26415 (TUM12135_50800) | 82305..82691 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| K6J93_RS26420 (TUM12135_50810) | 83273..83506 | + | 234 | Protein_94 | IS5 family transposase ISPan1 | Transposase |
| K6J93_RS26425 (TUM12135_50820) | 83539..86505 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J93_RS26430 (TUM12135_50830) | 86509..87069 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J93_RS26435 (TUM12135_50840) | 87245..87595 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J93_RS26440 (TUM12135_50850) | 87798..88811 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J93_RS26445 (TUM12135_50860) | 88978..89820 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J93_RS26450 (TUM12135_50870) | 89916..90524 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J93_RS26455 (TUM12135_50880) | 90582..91420 | + | 839 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J93_RS26460 | 91635..92894 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J93_RS26465 (TUM12135_50900) | 92987..93825 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J93_RS26470 (TUM12135_50910) | 93948..94280 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J93_RS26475 (TUM12135_50920) | 94527..95159 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J93_RS26480 (TUM12135_50930) | 95474..96454 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J93_RS26485 (TUM12135_50940) | 96560..97264 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J93_RS26490 (TUM12135_50950) | 97378..98154 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J93_RS26495 (TUM12135_50970) | 98383..99408 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J93_RS26500 | 99483..99770 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6J93_RS26505 (TUM12135_50980) | 99830..100582 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J93_RS26510 (TUM12135_50990) | 100644..101525 | + | 882 | Protein_112 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| K6J93_RS26515 | 101688..101771 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6J93_RS26520 (TUM12135_51000) | 102638..102913 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6J93_RS26525 (TUM12135_51010) | 103086..103400 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J93_RS26530 (TUM12135_51020) | 103655..104011 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J93_RS26535 (TUM12135_51030) | 104001..104402 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J93_RS26540 (TUM12135_51040) | 104399..104689 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J93_RS26545 (TUM12135_51050) | 104753..105151 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J93_RS26550 (TUM12135_51060) | 105151..108387 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J93_RS26555 (TUM12135_51070) | 108387..109916 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J93_RS26560 (TUM12135_51080) | 109918..110334 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J93_RS26565 (TUM12135_51090) | 110891..111277 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J93_RS26570 (TUM12135_51100) | 111286..112002 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J93_RS26575 (TUM12135_51110) | 112004..112372 | + | 369 | WP_012561138.1 | plasmid stabilization protein StbC | - |
| K6J93_RS26580 (TUM12135_51120) | 112573..112917 | + | 345 | WP_012561137.1 | hypothetical protein | - |
| K6J93_RS26585 (TUM12135_51130) | 113379..113558 | - | 180 | WP_012561134.1 | protein CcgAI | - |
| K6J93_RS26590 (TUM12135_51140) | 114909..115241 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| K6J93_RS26595 (TUM12135_51150) | 115450..115734 | - | 285 | WP_013263793.1 | protein CcgC | - |
| K6J93_RS26950 | 115803..116003 | - | 201 | WP_020319888.1 | hypothetical protein | - |
| K6J93_RS26605 (TUM12135_51170) | 116159..116455 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J93_RS26610 (TUM12135_51180) | 117339..117578 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J93_RS26615 (TUM12135_51190) | 117588..117992 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J93_RS26620 (TUM12135_51200) | 118050..118475 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J93_RS26625 (TUM12135_51210) | 118891..119331 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J93_RS26630 (TUM12135_51220) | 119319..120584 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J93_RS26635 (TUM12135_51230) | 120735..121526 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J93_RS26640 (TUM12135_51240) | 121541..121882 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|