MGE detailed information
MGE type: Conjugative plasmid MGE length: 123816 bp
Accession: NZ_AP024757 Location: 1..123816 Organism: Klebsiella pneumoniae strain TUM12128 Replicon: plasmid IncN-R
Accession: NZ_AP024757 Location: 1..123816 Organism: Klebsiella pneumoniae strain TUM12128 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J96_RS26045 (TUM12128_49970) | 1..720 | + | 720 | WP_012561120.1 | replication initiation protein | - |
| K6J96_RS26050 (TUM12128_49980) | 2231..2530 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J96_RS26055 (TUM12128_49990) | 2602..5253 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J96_RS27350 (TUM12128_50010) | 5672..5938 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J96_RS26060 | 5870..6555 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J96_RS26065 (TUM12128_50030) | 7228..8736 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J96_RS26070 | 8817..8996 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J96_RS26075 (TUM12128_50040) | 9278..10354 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J96_RS26080 | 10371..10647 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J96_RS26085 | 10762..10938 | + | 177 | Protein_9 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J96_RS26090 (TUM12128_50050) | 10953..11789 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J96_RS26095 (TUM12128_50060) | 11854..12252 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J96_RS26100 (TUM12128_50070) | 12296..13405 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J96_RS26105 (TUM12128_50080) | 13440..13715 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J96_RS26115 (TUM12128_50110) | 15137..15706 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J96_RS26120 (TUM12128_50120) | 15946..17160 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J96_RS26125 (TUM12128_50130) | 17194..18627 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J96_RS26130 (TUM12128_50140) | 18726..18998 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J96_RS26135 (TUM12128_50150) | 19009..19215 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J96_RS26140 (TUM12128_50160) | 19220..19861 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J96_RS26145 (TUM12128_50170) | 19917..20228 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J96_RS26150 (TUM12128_50180) | 20264..20578 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J96_RS26155 (TUM12128_50190) | 20575..20919 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J96_RS26160 (TUM12128_50200) | 20935..21240 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J96_RS26165 (TUM12128_50210) | 21349..22086 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J96_RS26170 (TUM12128_50220) | 22095..22376 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J96_RS26175 (TUM12128_50230) | 22386..22679 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J96_RS26180 (TUM12128_50240) | 22729..23046 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J96_RS26185 (TUM12128_50250) | 23046..25646 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J96_RS26190 (TUM12128_50260) | 25664..26377 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J96_RS26195 (TUM12128_50270) | 26385..26612 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J96_RS26200 (TUM12128_50280) | 26628..27668 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J96_RS26205 (TUM12128_50290) | 27887..28585 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J96_RS26210 (TUM12128_50300) | 28596..29480 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J96_RS26215 (TUM12128_50310) | 29480..30640 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J96_RS26220 (TUM12128_50320) | 30682..31677 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J96_RS26225 (TUM12128_50330) | 31677..31943 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J96_RS26230 (TUM12128_50340) | 32149..32280 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J96_RS26235 (TUM12128_50350) | 32337..33329 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J96_RS26240 | 33378..33533 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J96_RS26245 (TUM12128_50360) | 33828..35543 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J96_RS26250 (TUM12128_50370) | 35653..38682 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J96_RS26255 (TUM12128_50380) | 38789..39814 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J96_RS26260 (TUM12128_50390) | 39811..40590 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J96_RS26265 (TUM12128_50400) | 40878..41759 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J96_RS26270 (TUM12128_50410) | 42009..43328 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J96_RS26275 (TUM12128_50420) | 43605..44789 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J96_RS26280 (TUM12128_50430) | 44891..45121 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J96_RS26285 (TUM12128_50440) | 45293..45652 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J96_RS26290 | 46309..46719 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J96_RS26295 (TUM12128_50450) | 46818..47438 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J96_RS26300 (TUM12128_50460) | 47527..50424 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J96_RS26305 (TUM12128_50470) | 50497..51201 | + | 705 | WP_169724930.1 | IS6 family transposase IS26 | Transposase |
| K6J96_RS26310 | 51251..51361 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J96_RS26315 | 51380..52249 | + | 870 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J96_RS26320 (TUM12128_50490) | 52449..52784 | + | 336 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J96_RS26325 (TUM12128_50500) | 52950..53812 | + | 863 | Protein_57 | Beta-lactamase TEM | ARG |
| K6J96_RS26330 (TUM12128_50510) | 53962..54333 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6J96_RS26335 (TUM12128_50520) | 54398..55648 | - | 1251 | Protein_59 | transposase | - |
| K6J96_RS26340 (TUM12128_50530) | 55723..56391 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J96_RS26345 (TUM12128_50540) | 56427..56663 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J96_RS26350 (TUM12128_50550) | 56660..57022 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J96_RS26355 (TUM12128_50560) | 57040..58734 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J96_RS26360 (TUM12128_50570) | 58786..59208 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J96_RS26365 | 59244..59354 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J96_RS26375 (TUM12128_50600) | 60122..60811 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J96_RS26380 (TUM12128_50610) | 60885..61301 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J96_RS26385 (TUM12128_50620) | 61298..61528 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J96_RS26390 | 61485..61946 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J96_RS26395 (TUM12128_50630) | 62090..62440 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J96_RS26400 (TUM12128_50640) | 62491..63234 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J96_RS26405 (TUM12128_50650) | 63231..64007 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J96_RS27355 (TUM12128_50660) | 64065..64244 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J96_RS26410 (TUM12128_50670) | 64279..67284 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J96_RS26415 (TUM12128_50690) | 67446..68003 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J96_RS26420 (TUM12128_50700) | 68237..68791 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J96_RS26425 (TUM12128_50710) | 68861..69076 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J96_RS26430 (TUM12128_50720) | 69142..69846 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J96_RS26435 (TUM12128_50730) | 69901..70071 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J96_RS27360 (TUM12128_50740) | 70202..70300 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J96_RS26440 | 70429..70533 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J96_RS26445 (TUM12128_50750) | 71063..71929 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J96_RS26450 (TUM12128_50760) | 72106..72375 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J96_RS26455 (TUM12128_50770) | 72790..73995 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J96_RS26460 (TUM12128_50780) | 73995..74969 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J96_RS26465 (TUM12128_50790) | 75051..76322 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J96_RS26470 (TUM12128_50800) | 76322..76753 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J96_RS26475 (TUM12128_50810) | 77159..78646 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| K6J96_RS26480 | 78798..79495 | + | 698 | WP_223229472.1 | IS1 family transposase IS1X3 | Transposase |
| K6J96_RS26485 | 79505..79813 | + | 309 | Protein_91 | replication initiation protein | - |
| K6J96_RS26490 (TUM12128_50840) | 81216..82184 | + | 969 | WP_077259757.1 | IS5 family transposase IS903B | Transposase |
| K6J96_RS26495 (TUM12128_50850) | 82324..82710 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| K6J96_RS26500 (TUM12128_50860) | 83292..83525 | + | 234 | Protein_94 | IS5 family transposase ISPan1 | Transposase |
| K6J96_RS26505 (TUM12128_50870) | 83558..86524 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J96_RS26510 (TUM12128_50880) | 86528..87088 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J96_RS26515 (TUM12128_50890) | 87264..87614 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J96_RS26520 (TUM12128_50910) | 87817..88830 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J96_RS26525 (TUM12128_50920) | 88997..89839 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J96_RS26530 (TUM12128_50930) | 89935..90543 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J96_RS26535 (TUM12128_50940) | 90601..91439 | + | 839 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J96_RS26540 | 91654..92913 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J96_RS26545 (TUM12128_50960) | 93006..93844 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J96_RS26550 (TUM12128_50970) | 93967..94299 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J96_RS26555 (TUM12128_50980) | 94546..95178 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J96_RS26560 (TUM12128_50990) | 95493..96473 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J96_RS26565 (TUM12128_51000) | 96579..97283 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J96_RS26570 (TUM12128_51010) | 97397..98173 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J96_RS26575 (TUM12128_51030) | 98402..99427 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J96_RS26580 | 99502..99789 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6J96_RS26585 (TUM12128_51040) | 99849..100601 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J96_RS26590 (TUM12128_51050) | 100663..101544 | + | 882 | Protein_112 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| K6J96_RS26595 | 101707..101790 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6J96_RS26600 (TUM12128_51060) | 102657..102932 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6J96_RS26605 (TUM12128_51070) | 103105..103419 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J96_RS26610 (TUM12128_51080) | 103674..104030 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J96_RS26615 (TUM12128_51090) | 104020..104421 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J96_RS26620 (TUM12128_51100) | 104418..104708 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J96_RS26625 (TUM12128_51110) | 104772..105170 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J96_RS26630 (TUM12128_51120) | 105170..108406 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J96_RS26635 (TUM12128_51130) | 108406..109935 | - | 1530 | WP_000342688.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J96_RS26640 (TUM12128_51140) | 109937..110353 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J96_RS26645 (TUM12128_51150) | 110910..111296 | + | 387 | WP_013279398.1 | plasmid stabilization protein StbA | - |
| K6J96_RS26650 (TUM12128_51160) | 111305..112021 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J96_RS26655 (TUM12128_51170) | 112023..112394 | + | 372 | WP_221278788.1 | plasmid stabilization protein StbC | - |
| K6J96_RS27365 (TUM12128_51180) | 112600..112854 | + | 255 | WP_228740452.1 | hypothetical protein | - |
| K6J96_RS26665 (TUM12128_51190) | 113399..113578 | - | 180 | WP_012561134.1 | protein CcgAI | - |
| K6J96_RS26670 | 114417..114925 | - | 509 | Protein_128 | antirestriction protein ArdA | - |
| K6J96_RS26675 (TUM12128_51220) | 116284..116616 | - | 333 | WP_221275599.1 | hypothetical protein | - |
| K6J96_RS26680 (TUM12128_51230) | 116827..117111 | - | 285 | WP_221277214.1 | protein CcgC | - |
| K6J96_RS26685 (TUM12128_51240) | 117176..117538 | - | 363 | WP_221278790.1 | hypothetical protein | - |
| K6J96_RS26690 (TUM12128_51250) | 117535..117831 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J96_RS26695 (TUM12128_51260) | 118714..118953 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J96_RS26700 (TUM12128_51270) | 118963..119367 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J96_RS26705 (TUM12128_51280) | 119425..119850 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J96_RS26710 (TUM12128_51290) | 120266..120706 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J96_RS26715 (TUM12128_51300) | 120694..121959 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J96_RS26720 (TUM12128_51310) | 122110..122901 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J96_RS26725 (TUM12128_51320) | 122916..123257 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|