MGE detailed information
MGE type: Conjugative plasmid MGE length: 123779 bp
Accession: NZ_AP024751 Location: 1..123779 Organism: Klebsiella pneumoniae strain TUM12126 Replicon: plasmid IncN-R
Accession: NZ_AP024751 Location: 1..123779 Organism: Klebsiella pneumoniae strain TUM12126 Replicon: plasmid IncN-R
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6J82_RS26000 (TUM12126_50000) | 1..612 | + | 612 | WP_228740389.1 | replication initiation protein | - |
| K6J82_RS26005 (TUM12126_50010) | 2219..2518 | + | 300 | Protein_1 | IS66 family transposase ISEc22 | Transposase |
| K6J82_RS26010 (TUM12126_50020) | 2590..5241 | - | 2652 | WP_012561117.1 | UvrABC system protein A | VF |
| K6J82_RS26940 (TUM12126_50040) | 5660..5926 | - | 267 | WP_225247940.1 | hypothetical protein | - |
| K6J82_RS26015 | 5858..6543 | + | 686 | Protein_4 | IS3 family transposase ISEc14 | Transposase |
| K6J82_RS26020 (TUM12126_50060) | 7216..8724 | + | 1509 | WP_032417327.1 | group II intron reverse transcriptase/maturase | - |
| K6J82_RS26025 | 8805..8984 | + | 180 | Protein_6 | DDE-type integrase/transposase/recombinase | - |
| K6J82_RS26030 (TUM12126_50070) | 9266..10342 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| K6J82_RS26035 | 10359..10635 | + | 277 | Protein_8 | IS3 family transposase | - |
| K6J82_RS26040 | 10750..10926 | + | 177 | Protein_9 | resolvase | - |
| K6J82_RS26045 (TUM12126_50080) | 10941..11777 | - | 837 | WP_012561110.1 | S-formylglutathione hydrolase | - |
| K6J82_RS26050 (TUM12126_50090) | 11842..12240 | - | 399 | WP_012561111.1 | VOC family protein | - |
| K6J82_RS26055 (TUM12126_50100) | 12284..13393 | - | 1110 | WP_017384070.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| K6J82_RS26060 (TUM12126_50110) | 13428..13703 | - | 276 | WP_017384071.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| K6J82_RS26070 (TUM12126_50140) | 15125..15694 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| K6J82_RS26075 (TUM12126_50150) | 15934..17148 | + | 1215 | WP_005012528.1 | type II site-specific deoxyribonuclease | - |
| K6J82_RS26080 (TUM12126_50160) | 17182..18615 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| K6J82_RS26085 (TUM12126_50170) | 18714..18986 | + | 273 | Protein_18 | IS1 family transposase IS1X2 | Transposase |
| K6J82_RS26090 (TUM12126_50180) | 18997..19203 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| K6J82_RS26095 (TUM12126_50190) | 19208..19849 | - | 642 | WP_012561158.1 | restriction endonuclease | - |
| K6J82_RS26100 (TUM12126_50200) | 19905..20216 | - | 312 | WP_013279382.1 | hypothetical protein | - |
| K6J82_RS26105 (TUM12126_50210) | 20252..20566 | - | 315 | WP_016338363.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| K6J82_RS26110 (TUM12126_50220) | 20563..20907 | - | 345 | WP_012561155.1 | hypothetical protein | - |
| K6J82_RS26115 (TUM12126_50230) | 20923..21228 | - | 306 | WP_012561154.1 | H-NS family nucleoid-associated regulatory protein | - |
| K6J82_RS26120 (TUM12126_50240) | 21337..22074 | + | 738 | WP_013279384.1 | Type IV secretion system protein virB1 | VF |
| K6J82_RS26125 (TUM12126_50250) | 22083..22364 | + | 282 | WP_016338364.1 | transcriptional repressor KorA | - |
| K6J82_RS26130 (TUM12126_50260) | 22374..22667 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| K6J82_RS26135 (TUM12126_50270) | 22717..23034 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| K6J82_RS26140 (TUM12126_50280) | 23034..25634 | + | 2601 | WP_012561149.1 | Type IV secretion system protein virB4 | VF |
| K6J82_RS26145 (TUM12126_50290) | 25652..26365 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| K6J82_RS26150 (TUM12126_50300) | 26373..26600 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| K6J82_RS26155 (TUM12126_50310) | 26616..27656 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| K6J82_RS26160 (TUM12126_50320) | 27875..28573 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| K6J82_RS26165 (TUM12126_50330) | 28584..29468 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| K6J82_RS26170 (TUM12126_50340) | 29468..30628 | + | 1161 | WP_012561145.1 | Protein virB10 | VF |
| K6J82_RS26175 (TUM12126_50350) | 30670..31665 | + | 996 | WP_012561144.1 | Type IV secretion system protein VirB11 | VF |
| K6J82_RS26180 (TUM12126_50360) | 31665..31931 | + | 267 | Protein_37 | hypothetical protein | VF |
| K6J82_RS26185 (TUM12126_50370) | 32137..32268 | - | 132 | Protein_38 | hypothetical protein | VF |
| K6J82_RS26190 (TUM12126_50380) | 32325..33317 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| K6J82_RS26195 | 33366..33521 | - | 156 | WP_001404092.1 | hypothetical protein | - |
| K6J82_RS26200 (TUM12126_50390) | 33816..35531 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| K6J82_RS26205 (TUM12126_50400) | 35641..38670 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| K6J82_RS26210 (TUM12126_50410) | 38777..39802 | + | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J82_RS26215 (TUM12126_50420) | 39799..40578 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| K6J82_RS26220 (TUM12126_50430) | 40866..41747 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6J82_RS26225 (TUM12126_50440) | 41997..43316 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| K6J82_RS26230 (TUM12126_50450) | 43593..44777 | - | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| K6J82_RS26235 (TUM12126_50460) | 44879..45109 | + | 231 | Protein_48 | IS5 family transposase ISAeme7 | Transposase |
| K6J82_RS26240 (TUM12126_50470) | 45281..45640 | + | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| K6J82_RS26245 | 46297..46707 | - | 411 | WP_004152401.1 | hypothetical protein | - |
| K6J82_RS26250 (TUM12126_50480) | 46806..47426 | - | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| K6J82_RS26255 (TUM12126_50490) | 47515..50412 | - | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K6J82_RS26260 (TUM12126_50500) | 50485..51189 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J82_RS26265 | 51239..51349 | + | 111 | Protein_54 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| K6J82_RS26270 | 51409..52233 | + | 825 | Protein_55 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| K6J82_RS26275 (TUM12126_50530) | 52433..52750 | + | 318 | Protein_56 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J82_RS26280 (TUM12126_50540) | 52933..53793 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K6J82_RS26285 (TUM12126_50550) | 53943..54314 | - | 372 | Protein_58 | IS6 family transposase IS15DII | Transposase |
| K6J82_RS26290 (TUM12126_50560) | 54379..55629 | - | 1251 | Protein_59 | transposase | - |
| K6J82_RS26295 (TUM12126_50570) | 55704..56372 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6J82_RS26300 (TUM12126_50580) | 56408..56644 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6J82_RS26305 (TUM12126_50590) | 56641..57003 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6J82_RS26310 (TUM12126_50600) | 57021..58715 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6J82_RS26315 (TUM12126_50610) | 58767..59189 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6J82_RS26320 | 59225..59335 | - | 111 | Protein_65 | mercuric transport protein periplasmic component | - |
| K6J82_RS26330 (TUM12126_50640) | 60103..60792 | - | 690 | Protein_67 | AAA family ATPase | - |
| K6J82_RS26335 (TUM12126_50650) | 60866..61282 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6J82_RS26340 (TUM12126_50660) | 61279..61509 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6J82_RS26345 | 61466..61927 | + | 462 | WP_072202616.1 | hypothetical protein | - |
| K6J82_RS26350 (TUM12126_50670) | 62071..62421 | + | 351 | WP_000493378.1 | hypothetical protein | - |
| K6J82_RS26355 (TUM12126_50680) | 62472..63215 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| K6J82_RS26360 (TUM12126_50690) | 63212..63988 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| K6J82_RS26945 (TUM12126_50700) | 64046..64225 | - | 180 | Protein_74 | hypothetical protein | - |
| K6J82_RS26365 (TUM12126_50710) | 64260..67265 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6J82_RS26370 (TUM12126_50730) | 67427..67984 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6J82_RS26375 (TUM12126_50740) | 68218..68772 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K6J82_RS26380 (TUM12126_50750) | 68842..69057 | + | 216 | Protein_78 | IS6 family transposase IS15 | Transposase |
| K6J82_RS26385 (TUM12126_50760) | 69123..69827 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J82_RS26390 (TUM12126_50770) | 69882..70052 | + | 171 | Protein_80 | serine hydrolase | - |
| K6J82_RS26950 (TUM12126_50780) | 70183..70281 | - | 99 | Protein_81 | hypothetical protein | - |
| K6J82_RS26395 | 70410..70514 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| K6J82_RS26400 (TUM12126_50790) | 71044..71910 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| K6J82_RS26405 (TUM12126_50800) | 72087..72356 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| K6J82_RS26410 (TUM12126_50810) | 72771..73976 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| K6J82_RS26415 (TUM12126_50820) | 73976..74950 | + | 975 | WP_000064119.1 | ParB family protein | - |
| K6J82_RS26420 (TUM12126_50830) | 75032..76303 | - | 1272 | WP_001754953.1 | Y-family DNA polymerase | - |
| K6J82_RS26425 (TUM12126_50840) | 76303..76734 | - | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6J82_RS26430 | 77140..78696 | + | 1557 | Protein_89 | group II intron reverse transcriptase/maturase | - |
| K6J82_RS26435 | 78774..79468 | + | 695 | Protein_90 | IS1 family transposase IS1X3 | Transposase |
| K6J82_RS26440 | 79478..79786 | + | 309 | Protein_91 | replication initiation protein | - |
| K6J82_RS26445 (TUM12126_50900) | 81219..82140 | + | 922 | Protein_92 | IS5 family transposase IS903 | Transposase |
| K6J82_RS26955 | 82278..82662 | - | 385 | Protein_93 | plasmid stabilization protein StbA | - |
| K6J82_RS26455 (TUM12126_50910) | 83244..83477 | + | 234 | Protein_94 | transposase | - |
| K6J82_RS26460 (TUM12126_50920) | 83510..86476 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6J82_RS26465 (TUM12126_50930) | 86480..87040 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6J82_RS26470 (TUM12126_50940) | 87216..87566 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K6J82_RS26475 (TUM12126_50960) | 87769..88782 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K6J82_RS26480 (TUM12126_50970) | 88949..89791 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| K6J82_RS26485 (TUM12126_50980) | 89887..90495 | + | 609 | WP_000050382.1 | HAD family hydrolase | - |
| K6J82_RS26490 (TUM12126_50990) | 90553..91391 | + | 839 | Protein_101 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J82_RS26495 | 91606..92865 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K6J82_RS26500 (TUM12126_51010) | 92958..93796 | + | 839 | Protein_103 | Streptomycin 3''-adenylyltransferase | ARG |
| K6J82_RS26505 (TUM12126_51020) | 93919..94251 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K6J82_RS26510 (TUM12126_51030) | 94498..95130 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K6J82_RS26515 (TUM12126_51040) | 95445..96425 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| K6J82_RS26520 (TUM12126_51050) | 96531..97235 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6J82_RS26525 (TUM12126_51060) | 97349..98125 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K6J82_RS26530 (TUM12126_51080) | 98354..99379 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K6J82_RS26535 | 99454..99741 | + | 288 | Protein_110 | AAC(3) family N-acetyltransferase | - |
| K6J82_RS26540 (TUM12126_51090) | 99801..100553 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K6J82_RS26545 (TUM12126_51100) | 100615..101496 | + | 882 | Protein_112 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| K6J82_RS26550 | 101659..101742 | - | 84 | Protein_113 | SOS response-associated peptidase | - |
| K6J82_RS26555 (TUM12126_51110) | 102611..102886 | + | 276 | Protein_114 | Phospholipase D | VF |
| K6J82_RS26560 (TUM12126_51120) | 103059..103373 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| K6J82_RS26565 (TUM12126_51130) | 103628..103984 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K6J82_RS26570 (TUM12126_51140) | 103974..104375 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K6J82_RS26575 (TUM12126_51150) | 104372..104662 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K6J82_RS26580 (TUM12126_51160) | 104726..105124 | - | 399 | WP_012561143.1 | hypothetical protein | - |
| K6J82_RS26585 (TUM12126_51170) | 105124..108360 | - | 3237 | WP_012561142.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6J82_RS26590 (TUM12126_51180) | 108360..109889 | - | 1530 | WP_221275598.1 | type IV secretion system DNA-binding domain-containing protein | - |
| K6J82_RS26595 (TUM12126_51190) | 109891..110307 | - | 417 | WP_001749975.1 | hypothetical protein | - |
| K6J82_RS26600 (TUM12126_51200) | 110864..111252 | + | 389 | Protein_123 | plasmid stabilization protein StbA | - |
| K6J82_RS26605 (TUM12126_51210) | 111261..111977 | + | 717 | WP_012561139.1 | StbB family protein | - |
| K6J82_RS26960 (TUM12126_51220) | 111979..112143 | + | 165 | WP_228740387.1 | hypothetical protein | - |
| K6J82_RS26615 (TUM12126_51230) | 112556..112897 | + | 342 | WP_228740388.1 | hypothetical protein | - |
| K6J82_RS27040 | 113360..113540 | - | 181 | Protein_127 | protein CcgAI | - |
| K6J82_RS26620 | 114371..114879 | - | 509 | Protein_128 | antirestriction protein ArdA | - |
| K6J82_RS26625 (TUM12126_51250) | 116239..116571 | - | 333 | WP_221275599.1 | hypothetical protein | - |
| K6J82_RS27045 | 116781..117068 | - | 288 | Protein_130 | protein CcgC | - |
| K6J82_RS26630 (TUM12126_51270) | 117495..117791 | - | 297 | WP_000545925.1 | protein CcgD | - |
| K6J82_RS26635 (TUM12126_51280) | 118677..118916 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| K6J82_RS26640 (TUM12126_51290) | 118926..119330 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| K6J82_RS26645 (TUM12126_51300) | 119388..119813 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| K6J82_RS26650 (TUM12126_51310) | 120229..120669 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| K6J82_RS26655 (TUM12126_51320) | 120657..121922 | + | 1266 | WP_012561122.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| K6J82_RS26660 (TUM12126_51330) | 122073..122864 | + | 792 | WP_012561121.1 | SprT-like domain-containing protein | - |
| K6J82_RS26665 (TUM12126_51340) | 122879..123220 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|