MGE detailed information
MGE type: Conjugative plasmid MGE length: 139376 bp
Accession: NZ_AP021910 Location: 1..139376 Organism: Klebsiella pneumoniae strain WP2-S17-ESBL-02 Replicon: plasmid pWP2-S17-ESBL-02_1
Accession: NZ_AP021910 Location: 1..139376 Organism: Klebsiella pneumoniae strain WP2-S17-ESBL-02 Replicon: plasmid pWP2-S17-ESBL-02_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R06_RS25395 () | 101..1114 | - | 1014 | WP_016831068.1 | hypothetical protein | - |
| H7R06_RS25400 () | 1273..1344 | - | 72 | WP_071786674.1 | RepA leader peptide Tap | - |
| H7R06_RS25405 () | 1556..1825 | - | 270 | WP_016831067.1 | replication regulatory protein RepA | - |
| H7R06_RS25410 () | 1961..2440 | - | 480 | WP_069346050.1 | Phospholipase D | VF |
| H7R06_RS25415 () | 2616..2924 | - | 309 | WP_016831065.1 | hypothetical protein | - |
| H7R06_RS25420 () | 2921..3571 | - | 651 | WP_029498344.1 | DUF2726 domain-containing protein | - |
| H7R06_RS25425 () | 3627..3848 | - | 222 | WP_029497438.1 | hypothetical protein | - |
| H7R06_RS26620 () | 4318..4665 | - | 348 | Protein_7 | hypothetical protein | - |
| H7R06_RS25435 () | 4685..5281 | - | 597 | WP_016831061.1 | fertility inhibition protein FinO | - |
| H7R06_RS25440 () | 5353..6078 | - | 726 | WP_016831060.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| H7R06_RS25445 () | 6159..11417 | - | 5259 | WP_029498346.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7R06_RS25450 () | 11417..13699 | - | 2283 | Protein_11 | type IV conjugative transfer system coupling protein TraD | - |
| H7R06_RS25455 () | 14057..14788 | - | 732 | WP_004152629.1 | complement resistance protein TraT | - |
| H7R06_RS25460 () | 14978..15505 | - | 528 | WP_029498351.1 | conjugal transfer protein TraS | - |
| H7R06_RS25465 () | 15511..18360 | - | 2850 | WP_023329044.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R06_RS25470 () | 18360..19739 | - | 1380 | WP_023158000.1 | conjugal transfer protein TraH | - |
| H7R06_RS25475 () | 19717..20160 | - | 444 | WP_023158001.1 | F-type conjugal transfer protein TrbF | - |
| H7R06_RS25480 () | 20206..20763 | - | 558 | WP_023158002.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R06_RS25485 () | 20735..20974 | - | 240 | WP_023158003.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R06_RS25490 () | 20985..21737 | - | 753 | WP_015065535.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R06_RS25495 () | 21758..22084 | - | 327 | WP_015065534.1 | hypothetical protein | - |
| H7R06_RS25500 () | 22097..22345 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| H7R06_RS25505 () | 22323..22577 | - | 255 | WP_015065558.1 | conjugal transfer protein TrbE | - |
| H7R06_RS25510 () | 22609..24564 | - | 1956 | WP_101963440.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R06_RS25515 () | 24623..25270 | - | 648 | WP_015632510.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R06_RS25520 () | 25349..25525 | - | 177 | WP_162866177.1 | hypothetical protein | - |
| H7R06_RS25525 () | 25546..26535 | - | 990 | WP_015632509.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R06_RS25530 () | 26532..26933 | - | 402 | WP_023158005.1 | hypothetical protein | - |
| H7R06_RS25535 () | 26968..27603 | - | 636 | WP_020325113.1 | type-F conjugative transfer system protein TraW | - |
| H7R06_RS25540 () | 27603..27992 | - | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| H7R06_RS25545 () | 27992..30631 | - | 2640 | WP_071005061.1 | type IV secretion system protein TraC | - |
| H7R06_RS25550 () | 30703..31101 | - | 399 | WP_023158008.1 | hypothetical protein | - |
| H7R06_RS25555 () | 31109..31498 | - | 390 | WP_023158009.1 | hypothetical protein | - |
| H7R06_RS25560 () | 31541..31945 | - | 405 | WP_016831042.1 | hypothetical protein | - |
| H7R06_RS25565 () | 32012..32323 | - | 312 | WP_071005063.1 | hypothetical protein | - |
| H7R06_RS25570 () | 32324..32542 | - | 219 | WP_014386199.1 | hypothetical protein | - |
| H7R06_RS25575 () | 32566..32855 | - | 290 | Protein_36 | hypothetical protein | - |
| H7R06_RS25580 () | 32860..33283 | - | 424 | Protein_37 | hypothetical protein | - |
| H7R06_RS25585 () | 33415..33999 | - | 585 | WP_014386196.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R06_RS25590 () | 34022..34618 | - | 597 | Protein_39 | conjugal transfer protein TraP | - |
| H7R06_RS25595 () | 34611..36035 | - | 1425 | WP_023158013.1 | conjugal transfer protein TraB | - |
| H7R06_RS25600 () | 36035..36775 | - | 741 | WP_014386193.1 | type-F conjugative transfer system secretin TraK | - |
| H7R06_RS25605 () | 36762..37328 | - | 567 | WP_016831035.1 | type IV conjugative transfer system protein TraE | - |
| H7R06_RS25610 () | 37348..37653 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| H7R06_RS25615 () | 37667..38035 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| H7R06_RS25620 () | 38097..38303 | - | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| H7R06_RS25625 () | 38436..39155 | - | 720 | WP_016831034.1 | conjugal transfer protein TrbJ | - |
| H7R06_RS25630 () | 39355..39771 | - | 417 | WP_072145360.1 | relaxosome protein TraM | - |
| H7R06_RS25635 () | 40162..40647 | + | 486 | WP_004178063.1 | hypothetical protein | VF |
| H7R06_RS25640 () | 40680..41009 | - | 330 | WP_011977736.1 | hypothetical protein | - |
| H7R06_RS25645 () | 41042..41863 | - | 822 | WP_004182076.1 | DUF945 domain-containing protein | - |
| H7R06_RS25650 () | 42691..43254 | - | 564 | WP_004182054.1 | methyltransferase | - |
| H7R06_RS25655 () | 43302..44657 | - | 1356 | WP_004182052.1 | DUF3560 domain-containing protein | - |
| H7R06_RS25660 () | 44709..44939 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| H7R06_RS25665 () | 45031..45258 | - | 228 | WP_004182050.1 | hypothetical protein | - |
| H7R06_RS25670 () | 45985..46302 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| H7R06_RS25675 () | 46337..46591 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| H7R06_RS25680 () | 46828..47253 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| H7R06_RS25685 () | 47773..48003 | - | 231 | WP_004118481.1 | hypothetical protein | - |
| H7R06_RS25690 () | 48237..49772 | - | 1536 | WP_164849034.1 | group II intron reverse transcriptase/maturase | - |
| H7R06_RS25695 () | 50174..50599 | + | 426 | WP_004182047.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| H7R06_RS25700 () | 50599..51870 | + | 1272 | WP_023157784.1 | Y-family DNA polymerase | - |
| H7R06_RS25705 () | 51949..52200 | + | 252 | WP_004182043.1 | hypothetical protein | - |
| H7R06_RS25710 () | 52445..54397 | - | 1953 | WP_000037308.1 | DUF262 domain-containing HNH endonuclease family protein | - |
| H7R06_RS25715 () | 54394..55674 | - | 1281 | WP_004182042.1 | DUF262 domain-containing protein | - |
| H7R06_RS25720 () | 56642..57337 | + | 696 | Protein_65 | IS1 family transposase IS1S | Transposase |
| H7R06_RS25725 () | 58112..59231 | - | 1120 | Protein_66 | IS3 family transposase ISSen4 | Transposase |
| H7R06_RS25730 () | 60274..61245 | - | 972 | WP_004182039.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7R06_RS25735 () | 61245..62411 | - | 1167 | WP_004182032.1 | Sporulation initiation inhibitor protein Soj | VF |
| H7R06_RS25740 () | 63163..64173 | + | 1011 | WP_004182030.1 | RepB family plasmid replication initiator protein | - |
| H7R06_RS25745 () | 64891..65631 | - | 741 | WP_020324066.1 | tyrosine-type recombinase/integrase | - |
| H7R06_RS25750 () | 66775..67722 | + | 948 | WP_004182028.1 | sensor domain-containing diguanylate cyclase | - |
| H7R06_RS25755 () | 67749..68060 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| H7R06_RS25760 () | 68080..69048 | + | 969 | WP_068814619.1 | IS5 family transposase IS903B | Transposase |
| H7R06_RS25765 () | 69721..69978 | - | 258 | WP_004197688.1 | hypothetical protein | - |
| H7R06_RS25770 () | 70598..72034 | + | 1437 | WP_080895248.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| H7R06_RS25775 () | 73017..74294 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| H7R06_RS25780 () | 74357..76354 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| H7R06_RS25785 () | 76506..77203 | - | 698 | Protein_78 | IS1 family transposase IS1X2 | Transposase |
| H7R06_RS25795 () | 78692..79176 | + | 485 | Protein_80 | IS1 family transposase IS1X2 | Transposase |
| H7R06_RS25800 () | 79192..79734 | + | 543 | Protein_81 | ISL3 family transposase ISKpn25 | Transposase |
| H7R06_RS25805 () | 80030..80461 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| H7R06_RS25810 () | 80712..82187 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| H7R06_RS25815 () | 82180..82860 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| H7R06_RS25820 () | 83050..84435 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| H7R06_RS25825 () | 84464..84817 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| H7R06_RS25830 () | 84931..86223 | + | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| H7R06_RS25835 () | 86234..89380 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| H7R06_RS25840 () | 89467..89907 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| H7R06_RS25845 () | 90034..92481 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| H7R06_RS25850 () | 92522..92719 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| H7R06_RS25855 () | 92753..93490 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| H7R06_RS25860 () | 93779..94228 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| H7R06_RS25865 () | 94462..96279 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| H7R06_RS25870 () | 96285..97175 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| H7R06_RS25875 () | 97215..97595 | + | 381 | WP_001549790.1 | copper resistance system metallochaperone PcoC | - |
| H7R06_RS25880 () | 97600..98529 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| H7R06_RS25885 () | 98584..99264 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| H7R06_RS25890 () | 99261..100661 | + | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| H7R06_RS25895 () | 100877..101311 | + | 435 | WP_004118347.1 | hypothetical protein | - |
| H7R06_RS25900 () | 101690..101788 | - | 99 | WP_032445197.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H7R06_RS25905 () | 101775..101954 | - | 180 | WP_004118349.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| H7R06_RS25910 () | 102267..102530 | + | 264 | WP_009310051.1 | hypothetical protein | - |
| H7R06_RS25915 () | 102527..103093 | + | 567 | WP_009310052.1 | hypothetical protein | - |
| H7R06_RS25920 () | 103124..103618 | + | 495 | WP_004213594.1 | hypothetical protein | - |
| H7R06_RS25925 () | 103679..103882 | + | 204 | WP_004150739.1 | hemolysin expression modulator Hha | - |
| H7R06_RS25930 () | 103976..105144 | + | 1169 | WP_182913155.1 | IS3 family transposase ISLad1 | Transposase |
| H7R06_RS25935 () | 105574..107127 | - | 1554 | WP_020324174.1 | L-lactate permease | - |
| H7R06_RS25940 () | 107563..109260 | + | 1698 | WP_020324177.1 | D-lactate dehydrogenase | - |
| H7R06_RS25945 () | 109335..110054 | + | 720 | WP_001102107.1 | (Fe-S)-binding protein | - |
| H7R06_RS25950 () | 110065..111492 | + | 1428 | WP_000023895.1 | iron-sulfur cluster-binding protein | - |
| H7R06_RS25955 () | 111485..112180 | + | 696 | WP_004118595.1 | lactate utilization protein C | - |
| H7R06_RS25960 () | 112230..112610 | - | 381 | Protein_113 | gluconate permease | - |
| H7R06_RS25965 () | 112821..113132 | + | 312 | WP_004118600.1 | type II toxin-antitoxin system HigB family toxin | Toxin Detail |
| H7R06_RS25970 () | 113129..113548 | + | 420 | WP_000990392.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| H7R06_RS25975 () | 113585..114787 | - | 1203 | WP_003031541.1 | hypothetical protein | - |
| H7R06_RS25980 () | 114780..115109 | - | 330 | WP_004118613.1 | hypothetical protein | - |
| H7R06_RS25985 () | 115106..115765 | - | 660 | WP_000078540.1 | hypothetical protein | - |
| H7R06_RS25990 () | 116189..116782 | - | 594 | WP_044348674.1 | hypothetical protein | - |
| H7R06_RS25995 () | 117098..117451 | + | 354 | WP_001114073.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| H7R06_RS26000 () | 117499..117861 | + | 363 | WP_020324593.1 | arsenite efflux transporter metallochaperone ArsD | - |
| H7R06_RS26005 () | 117879..119630 | + | 1752 | WP_001556710.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| H7R06_RS26010 () | 119679..120968 | + | 1290 | WP_000922630.1 | arsenite efflux transporter membrane subunit ArsB | - |
| H7R06_RS26015 () | 120981..121406 | + | 426 | WP_000065758.1 | glutaredoxin-dependent arsenate reductase | - |
| H7R06_RS26020 () | 121437..121811 | - | 375 | WP_000110555.1 | arsenic transporter ATPase | - |
| H7R06_RS26025 () | 121886..122199 | - | 314 | Protein_126 | Tn3 family transposase | - |
| H7R06_RS26030 () | 122226..122978 | - | 753 | WP_020324592.1 | alpha/beta hydrolase | - |
| H7R06_RS26035 () | 123220..124050 | + | 831 | WP_020324597.1 | DMT family transporter | - |
| H7R06_RS26040 () | 124181..125404 | + | 1224 | WP_000872613.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| H7R06_RS26045 () | 125590..126363 | - | 774 | WP_001091224.1 | SDR family oxidoreductase | - |
| H7R06_RS26050 () | 126429..127130 | - | 702 | WP_008502228.1 | DsbA family oxidoreductase | - |
| H7R06_RS26055 () | 127196..128302 | - | 1107 | WP_006687059.1 | alkene reductase | - |
| H7R06_RS26060 () | 128515..128844 | + | 330 | WP_008502229.1 | thioredoxin family protein | - |
| H7R06_RS26065 () | 128874..129212 | - | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| H7R06_RS26070 () | 129217..129798 | - | 582 | WP_008502230.1 | HTH-type transcriptional repressor NemR | VF |
| H7R06_RS26075 () | 129940..130497 | - | 558 | WP_032445547.1 | OsmC family protein | - |
| H7R06_RS26080 () | 130684..131052 | - | 369 | Protein_137 | recombinase family protein | - |
| H7R06_RS26085 () | 131117..131821 | + | 705 | Protein_138 | IS6 family transposase IS26 | Transposase |
| H7R06_RS26090 () | 131874..132104 | + | 231 | Protein_139 | replication initiation protein | - |
| H7R06_RS26095 () | 133806..135281 | + | 1476 | WP_020324153.1 | SEC-C domain-containing protein | - |
| H7R06_RS26100 () | 135645..136349 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7R06_RS26105 () | 136365..138085 | + | 1721 | Protein_142 | DEAD/DEAH box helicase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|