TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci
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Toxin-antitoxin (TA) loci play a role in bacterial stress physiology and the stabilisation of horizontally acquired elements. TA loci are found abundantly distributed among free-living Bacteria and Archaea.
TA loci code for a stable toxin that is neutralized by a short-lived antitoxin. The antitoxin can be either an antisense RNA (Type 1 TA loci) or a protein (Type 2 TA loci).
To date, six type TA systems have been reported (see the recent review of Rebecca Page & Wolfgang PetiNature in Chemical Biology 2016, 12, 208–214).
The aim of this PostgreSQL-based TADB database is to create and maintain a resource of all currently available type II TA loci-relevant data
ranging from 'wet' experimental data to information garnered by bioinformatics analyses.
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Reference for TADB 2.0: Y. Xie, Y. Wei, Y. Shen, X. Li, H. Zhou, C. Tai, Z. Deng and H.Y. Ou (2018)
TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci. Nucleic Acids Research, 2018, 46:D749-D753. [Abstract] |
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Reference for TADB 1.0: Y. Shao, E.M. Harrison, D. Bi, C. Tai, X. He, H.Y. Ou, K. Rajakumar and Z. Deng (2011)
TADB: a web-based resource for Type 2 toxin-antitoxin loci in Bacteria and Archaea. Nucleic Acids Research, 39, D606-D611. [Abstract] |
Current version: 2.0
Since Dec., 2010; Updated: Oct., 2017 |
Suggested Browsers: Google Chrome
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