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Effector Protein ID: 33603863

T4SS name [ID]	Ptl [379]
Gene symbol
Locus tag
Strain	Bordetella bronchiseptica RB50
Replicon	chromosome [GenBank: NC_002927] [Browse all T4SS(s) in this replicon]
Location [Strand]	5198963..5199772 []
Product
Effector type	Protein
Descripton	PtxA
T4CP requirement	T4CP Indepedent
Target/Effection	A subunit of pertussis toxin (PT). PT is involved in the colonization of the respiratory tract and the establishment of infection of Bordetella pertussis causing whooping cough
UniProt ID	Q7WDU8
KEGG ID	bbr:BB4890
PDB ID	NA
Domain hit(s) vs Pfam	Pertussis_S1 [PF02917], Evalue: 1.4e-131, Aligned region: 36..268

Protein Sequence: a.a.     [Download]

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Nucleotide Sequence: bp     [Download]

Reference

(1) Parkhill J; Sebaihia M; Preston A; Murphy LD; Thomson N; Harris DE; Holden MT; Churcher CM; Bentley SD; Mungall KL; Cerdeno-Tarraga AM; Temple L; James K; Harris B; Quail MA; Achtman M; Atkin R; Baker S; Basham D; Bason N; Cherevach I; Chillingworth T; Collins M; Cronin A; Davis P; Doggett J; Feltwell T; Goble A; Hamlin N; Hauser H; Holroyd S; Jagels K; Leather S; Moule S; Norberczak H; O'Neil S; Ormond D; Price C; Rabbinowitsch E; Rutter S; Sanders M; Saunders D; Seeger K; Sharp S; Simmonds M; Skelton J; Squares R; Squares S; Stevens K; Unwin L; Whitehead S; Barrell BG; Maskell DJ (2003). Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nat Genet. 35(1):32-40. [PudMed:12910271]