SecReT4
T4SS ID448
StrainHelicobacter pylori B38
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_012973
Location13578..16487; 36264..40300
NameComB
FunctionDNA uptake
ClassificationType IVA; Type P
insolico Bioinformatics investigation has been performed on this T4SS.

T4SS components
ComponentComB2ComB3ComB4ComB6ComB7ComB8ComB9ComB10
Number11110111

The information of T4SS components from NC_012973
Region 1: 13578..16487
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1HELPY_0009 (groES)9144..9500 [-], 357254778747co-chaperonin GroES 
2HELPY_0010 (dnaG)9787..11466 [+], 1680254778748DNA primase 
3HELPY_001111463..12515 [+], 1053254778749hypothetical protein 
4HELPY_001212605..13432 [+], 828254778750hypothetical protein 
5HELPY_001313578..13859 [+], 282254778751hypothetical protein  ComB2
6HELPY_001413859..14122 [+], 264254778752hypothetical protein  ComB3
7HELPY_0015 (comB4)14124..16487 [+], 2364254778753ATPase/DNA transfer protein  ComB4
8HELPY_001616670..18121 [+], 1452254778754hypothetical protein 
9HELPY_0017 (cheV1)18229..19194 [+], 966254778755Chemotaxis protein (Che V) 
10HELPY_0018 (nspC)19191..20408 [+], 1218254778756Carboxynorspermidine decarboxylase 
11HELPY_001920418..20990 [-], 573254778757lipid A 1-phosphatase 
 
Region 2: 36264..40300
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1HELPY_002931676..32089 [+], 414254778766universal stress global response regulator UspA 
2HELPY_0030 (clpS)32104..32379 [+], 276254778767ATP-dependent Clp protease adaptor protein ClpS 
3HELPY_0031 (clpA)32379..34604 [+], 2226254778768ATP-dependent Clp protease ATP-binding subunit ClpA 
4HELPY_0032 (panD)34606..34947 [+], 342254778769aspartate alpha-decarboxylase 
5HELPY_003334950..35252 [+], 303254778770hypothetical protein 
6HELPY_003435249..36256 [+], 1008254778771hypothetical protein 
7HELPY_003536264..37319 [+], 1056254778772hypothetical protein  ComB6
8HELPY_0036 (comB8)37445..38188 [+], 744254778773DNA transformation competence protein ComB8  ComB8
9HELPY_0037 (comB9)38188..39177 [+], 990254778774DNA transformation competence protein ComB9  ComB9
10HELPY_0038 (comB10)39170..40300 [+], 1131254778775DNA transformation competence protein ComB10  ComB10
11HELPY_0039 (manC)40371..41783 [+], 1413254778776Alginate biosynthesis protein AlgA 
12HELPY_0040 (gmd)41824..42969 [+], 1146254778777GDP-mannose 4,6-dehydratase 
13HELPY_0041 (fcl)42962..43894 [+], 933254778778Bifunctional GDP-fucose synthetase 
14HELPY_0042 (hypE)44210..45208 [-], 999254778779Hydrogenase expression/formation protein 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes
(1) Fischer W; Windhager L; Rohrer S; Zeiller M; Karnholz A; Hoffmann R; Zimmer R; Haas R (2010). Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer. Nucleic Acids Res. 38(18):6089-101. [PudMed:20478826] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation