SecReT4

T4SS
References

T4SS ID	441
Strain	Helicobacter pylori J99
Replicon	chromosome [Browse all T4SS(s) in this replicon]
Accession	NC_000921
Location	13859..16768; 36686..40719
Name	ComB
Function	DNA uptake
Classification	Type IVA; Type P
Experimental investigation has been performed on this T4SS.

T4SS components

Component	ComB2	ComB3	ComB4	ComB6	ComB7	ComB8	ComB9	ComB10
Number	1	1	1	1	0	1	1	1

The information of T4SS components from NC_000921
Region 1: 13859..16768

#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	jhp0009 (groES)	9423..9779 [-], 357	15611080	co-chaperonin GroES
2	jhp0010 (dnaG)	10067..11746 [+], 1680	15611081	DNA primase
3	jhp0011	11743..12795 [+], 1053	15611082	hypothetical protein
4	jhp0012	12885..13712 [+], 828	15611083	hypothetical protein
5	jhp0013	13859..14140 [+], 282	15611084	hypothetical protein	ComB2
6	jhp0014	14140..14403 [+], 264	15611085	hypothetical protein	ComB3
7	jhp0015 (virB4_1)	14405..16768 [+], 2364	15611086	DNA transfer protein	ComB4
8	jhp0016	17008..18417 [+], 1410	15611087	hypothetical protein
9	jhp0017 (cheV_1)	18524..19489 [+], 966	15611088	chemotaxis protein
10	jhp0018 (nspC)	19486..20703 [+], 1218	15611089	carboxynorspermidine decarboxylase
11	jhp0019	20764..21339 [-], 576	15611090	lipid A 1-phosphatase

Region 2: 36686..40719

#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	jhp0027	32111..32524 [+], 414	15611098	hypothetical protein
2	jhp0028	32526..32798 [+], 273	15611099	hypothetical protein
3	jhp0029 (clpA)	32798..35026 [+], 2229	15611100	ATP-dependent protease ATP-binding protein
4	jhp0030 (panD)	35016..35369 [+], 354	15611101	aspartate alpha-decarboxylase
5	jhp0031	35372..35674 [+], 303	15611102	hypothetical protein
6	jhp0032	35671..36678 [+], 1008	15611103	hypothetical protein
7	jhp0033	36686..37741 [+], 1056	15611104	hypothetical protein	ComB6
8	jhp0034 (comB1)	37867..38610 [+], 744	15611105	DNA transformation competancy	ComB8
9	jhp0035 (comB2)	38610..39596 [+], 987	15611106	DNA transformation compentancy	ComB9
10	jhp0036 (comB3)	39589..40719 [+], 1131	15611107	DNA transformation compentancy	ComB10
11	jhp0037 (manC)	40789..42201 [+], 1413	15611108	phosphomannose isomerase/GDP-mannose pyrophosphorylase
12	jhp0038 (gmd)	42242..43387 [+], 1146	15611109	GDP-D-mannose dehydratase
13	jhp0039	43380..44312 [+], 933	15611110	sugar nucleotide biosynthesis

Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files

Proteins Genes

(1) Stingl K; Muller S; Scheidgen-Kleyboldt G; Clausen M; Maier B (2010). Composite system mediates two-step DNA uptake into Helicobacter pylori. Proc Natl Acad Sci U S A. 107(3):1184-9. [PudMed:20080542]

(2) Karnholz A; Hoefler C; Odenbreit S; Fischer W; Hofreuter D; Haas R (2006). Functional and topological characterization of novel components of the comB DNA transformation competence system in Helicobacter pylori. J Bacteriol. 188(3):882-93. [PudMed:16428391]

This literature contains experimental investigation

This literature contains bioinformatics investigation