 ICEberg ID | 5_IME |
Name  | ermF region  |
| Family | - |
| Organism | Bacteroides thetaiotaomicron |
| Size (bp) | 13 kb |
| GC content [Genome] (%) | |
| Insertion site | - |
| Function | ermF (clindamycin, erythromycin) |
| Species that IME can be transferred to | - |
| Nucleotide Sequence | AJ311171 (complete IME sequence in this contig) |
| Replicon | - |
| Coordinates | 2672..15432 |
| Putative oriT region | - |
| Putative relaxase | coordinates: 7955..8866; Gene: mobA; Family: MOBP |
The Interaction Network among ICE/IME/CIME/plasmid | ||||||
 | ||||||
| Detailed Informatioin of the Interaction Network | ||||||
| # | IME | Inter_Ele [Type] | Methods | Donors | Recipients | Exper_Ref |
| 1 | ermF region | CTnDOT [ICE] | in trans | Bacteroides thetaiotaomicron | Bacteroides thetaiotaomicron | 11472924 |
| 2 | ermF region | CTnERL [ICE] | in trans | Bacteroides thetaiotaomicron | Bacteroides thetaiotaomicron | 11472924 |
| This is an interactioin derived from experimental literature |
The graph information of ermF region components from AJ311171 | |||||
 | |||||
| Complete gene list of ermF region from AJ311171 | |||||
| # | Gene | Coordinates [+/-], size (bp) | Product | *Reannotation | |
| 1 | intDOT | 847..2082 [+], 1236 | integrase protein | ||
| 2 | - | 2095..2457 [+], 363 | hypothetical protein | ||
| 3 | intF | 2672..4006 [+], 1335 | putative integrase | ||
| 4 | - | 4011..4196 [+], 186 | hypothetical protein | ||
| 5 | - | 5172..5471 [+], 300 | hypothetical protein | ||
| 6 | - | 5649..6518 [+], 870 | hypothetical protein | ||
| 7 | prmF | 6589..7542 [+], 954 | hypothetical protein | ||
| 8 | mobB | 7612..7974 [+], 363 | MobB protein | ||
| 9 | mobA | 7955..8866 [+], 912 | MobA protein | Relaxase | |
| 10 | - | 8871..9464 [+], 594 | hypothetical protein | ||
| 11 | aadS | 9763..10599 [-], 837 | aminoglycoside 6-adenylyltransferase | ||
| 12 | tetX2 | 10775..11941 [-], 1167 | TetX2 protein | AR | |
| 13 | tetX1 | 12110..13189 [-], 1080 | TetX1 protein | ||
| 14 | ermF | 13555..14355 [+], 801 | rRNA adenine-N6 methyltransferase | AR | |
| 15 | tpnF | 14593..15432 [+], 840 | TpnF protein | Integrase | |
| 16 | - | 15901..16218 [-], 318 | hypothetical protein | ||
| 17 | - | 16249..16734 [-], 486 | hypothetical protein | ||
 Flanking regions |
 Gene may contribute to site-specific recombination |
 Gene may play role in conjugative transfer |
 Gene may be involved in adaptative function |
| (1) Bellanger X; Payot S; Leblond-Bourget N; Guedon G (2014). Conjugative and mobilizable genomic islands in bacteria: evolution and diversity. FEMS Microbiol Rev. 38(4):720-60. [PudMed:24372381] |
|
(2) Whittle G; Hund BD; Shoemaker NB; Salyers AA (2001). Characterization of the 13-kilobase ermF region of the Bacteroides conjugative transposon CTnDOT. Appl Environ Microbiol. 67(8):3488-95. [PudMed:11472924]
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| experimental literature |