 ICEberg ID | 213_IME |
Name  | SGI1-K  |
| Family | - |
| Organism | Proteus mirabilis PmSC17 |
| Size (bp) | 48754 bp |
| GC content [Genome] (%) | |
| Insertion site | 3'-end of the trmE |
| Function | aacCA5, aadA7, blaTEM-1b, strAB, sul1, tet(A), mercuric ion resistance |
| Species that IME can be transferred to | Escherichia coli UB1637 |
| Nucleotide Sequence | AY463797 (complete IME sequence in this contig) |
| Replicon | - |
| Coordinates | 1146..49899 |
| Putative oriT region | - |
| Putative relaxase | - |
The Interaction Network among ICE/IME/CIME/plasmid | ||||||
 | ||||||
| Detailed Informatioin of the Interaction Network | ||||||
| # | IME | Inter_Ele [Type] | Methods | Donors | Recipients | Exper_Ref |
| 1 | SGI1-K | pRMH760 [IncC plasmid] | in trans | Salmonella enterica | Escherichia coli | 27620651 |
| This is an interactioin derived from experimental literature |
The graph information of SGI1-K components from AY463797 | |||||
 | |||||
| Complete gene list of SGI1-K from AY463797 | |||||
| # | Gene | Coordinates [+/-], size (bp) | Product | *Reannotation | |
| 1 | trmE | 447..1163 [+], 717 | TrmE | ||
| 2 | int SGI | 1367..2584 [+], 1218 | integrase | ||
| 3 | S002 | 2581..2949 [-], 369 | S002 | ||
| 4 | rep | 3307..4260 [-], 954 | Rep | ||
| 5 | S004 | 4247..4537 [-], 291 | S004 | ||
| 6 | orfB | 6349..7221 [-], 873 | IS1359 transposase; OrfB | ||
| 7 | orfA | 7218..7562 [-], 345 | IS1359 transposase; OrfA | ||
| 8 | traG | 8067..11471 [-], 3405 | TraG | TraG_F, T4SS component | |
| 9 | TraH | 11475..12899 [-], 1425 | TraH | TraH_F, T4SS component | |
| 10 | S013 | 13143..14000 [+], 858 | hypothetical protein | ||
| 11 | S014 | 13997..14392 [+], 396 | hypothetical protein | ||
| 12 | S015 | 14807..15076 [-], 270 | hypothetical protein | ||
| 13 | S016 | 15154..15339 [-], 186 | hypothetical protein | ||
| 14 | S017 | 15199..15453 [+], 255 | hypothetical protein | ||
| 15 | S018 | 15350..15667 [-], 318 | hypothetical protein | ||
| 16 | S019 | 15925..16221 [-], 297 | hypothetical protein | ||
| 17 | S020 | 16225..17190 [-], 966 | putative integrase | ||
| 18 | S021 | 17283..17618 [+], 336 | hypothetical protein | ||
| 19 | S022 | 17530..17805 [-], 276 | hypothetical protein | ||
| 20 | S023 | 18166..19806 [-], 1641 | putative helicase | ||
| 21 | S024 | 19824..21749 [-], 1926 | putative exonuclease | ||
| 22 | S025 | 21827..24370 [-], 2544 | putative proteinase subtilisin-like protein | ||
| 23 | S026 | 24391..25380 [-], 990 | putative ATPase | ||
| 24 | resG | 25459..26043 [-], 585 | ResG | ||
| 25 | intI1 | 26317..27330 [-], 1014 | IntI1 integrase | Integrase | |
| 26 | aacCA5 | 27488..27964 [+], 477 | aminoglycoside (3) acetyltransferase; AacCA5 or AAC(3)-Ie | ||
| 27 | aadA7 | 28040..28837 [+], 798 | aminoglycoside (3'')(9) adenylyltransferase; AAD(3'')(9) | ||
| 28 | qacEdelta1 | 29001..29348 [+], 348 | QacEdelta1 | ||
| 29 | sul1 | 29342..30181 [+], 840 | sulfonamide insensitive dihydropteroate synthase | AR | |
| 30 | tnp6100 | 30525..31319 [+], 795 | tnp6100 | ||
| 31 | merE | 32325..32561 [-], 237 | MerE | ||
| 32 | merD | 32558..32923 [-], 366 | MerD | ||
| 33 | merA | 32941..34623 [-], 1683 | MerA | ||
| 34 | merC | 34675..35097 [-], 423 | MerC | ||
| 35 | merP | 35133..35408 [-], 276 | MerP | ||
| 36 | merT | 35422..35772 [-], 351 | MerT | ||
| 37 | merR | 35844..36278 [+], 435 | MerR | ||
| 38 | tetR(A) | 36484..37134 [-], 651 | TetR(A) | ||
| 39 | tetA(A) | 37240..38439 [+], 1200 | TetA(A) | AR | |
| 40 | strB | 42179..43015 [-], 837 | StrB | AR | |
| 41 | strA | 43015..43818 [-], 804 | StrA | AR | |
| 42 | tnpA1133 | 43925..44782 [-], 858 | TnpA | ||
| 43 | tnp26 | 45682..46386 [+], 705 | Tnp26 | ||
| 44 | tnpR | 46625..47182 [+], 558 | Tn2 resolvase | ||
| 45 | blaTEM-1b | 47364..48224 [+], 861 | BlaTEM-1b beta lactamase | AR | |
| 46 | tnp26 | 48685..49389 [-], 705 | Tnp26 | ||
| 47 | yidY | 50100..51287 [+], 1188 | YidY | AR | |
 Flanking regions |
 Gene may contribute to site-specific recombination |
 Gene may play role in conjugative transfer |
 Gene may be involved in adaptative function |
| (1) de Curraize C; Neuwirth C; Bador J; Chapuis A; Amoureux L; Siebor E (2018). Two new Salmonella genomic islands 1 from Proteus mirabilis and description of blaCTX-M-15 on a variant (SGI1-K7). J Antimicrob Chemother. . [PudMed:29659873] |
| (2) Guedon G; Libante V; Coluzzi C; Payot S; Leblond-Bourget N (2017). The Obscure World of Integrative and Mobilizable Elements, Highly Widespread Elements that Pirate Bacterial Conjugative Systems. Genes (Basel). 8(11). [PudMed:29165361] |
| (3) Harmer CJ; Hamidian M; Ambrose SJ; Hall RM (2016). Destabilization of IncA and IncC plasmids by SGI1 and SGI2 type Salmonella genomic islands. Plasmid. 87-88:51-57. [PudMed:27620651] |
| (4) Hamidian M; Holt KE; Hall RM (2015). The complete sequence of Salmonella genomic island SGI1-K. J Antimicrob Chemother. 70(1):305-6. [PudMed:25193084] |
| (5) Doublet B; Praud K; Bertrand S; Collard JM; Weill FX; Cloeckaert A (2008). Novel insertion sequence- and transposon-mediated genetic rearrangements in genomic island SGI1 of Salmonella enterica serovar Kentucky. Antimicrob Agents Chemother. 52(10):3745-54. [PudMed:18676889] |
| (6) Levings RS; Partridge SR; Djordjevic SP; Hall RM (2007). SGI1-K, a variant of the SGI1 genomic island carrying a mercury resistance region, in Salmonella enterica serovar Kentucky. Antimicrob Agents Chemother. 51(1):317-23. [PudMed:17088481] |