I. Information of IME

ICEberg ID	198_IME
Name	PGI1-PmPEL
Family	-
Organism	Proteus mirabilis PEL
Size (bp)	64.4 kb
GC content [Genome] (%)
Insertion site	3'-end of the trmE
Function	blaNDM-1, aadB, aadA2
Species that IME can be transferred to	-
Nucleotide Sequence	KF856624 (complete IME sequence in this contig)
Replicon	-
Coordinates	469..65262
Putative oriT region	-
Putative relaxase	-

II. IME interaction with ICE/CIME/Plasmids

The interaction information of PGI1-PmPEL is not available.

The graph information of PGI1-PmPEL components from KF856624
Complete gene list of PGI1-PmPEL from KF856624
#	Gene	Coordinates [+/-], size (bp)	Product	*Reannotation
1	thdF	1..468 [+], 468	ThdF
2	intI1	671..1906 [+], 1236	IntI1
3	repA	2406..3647 [-], 1242	RepA
4	traN	4262..6997 [-], 2736	TraN	TraN_F, T4SS component
5	-	7084..7626 [-], 543	hypothetical protein
6	-	7629..7817 [-], 189	hypothetical protein
7	-	8070..8249 [+], 180	hypothetical protein
8	traG	8653..12090 [-], 3438	TraG-like protein	TraG_F, T4SS component
9	-	12299..13165 [+], 867	hypothetical protein
10	helC2	13430..16015 [+], 2586	HelC2
11	-	16521..16958 [-], 438	hypothetical protein
12	-	17324..17599 [-], 276	hypothetical protein
13	-	18205..18342 [+], 138	hypothetical protein
14	-	18817..18936 [+], 120	hypothetical protein
15	intI1	19049..20014 [-], 966	IntI1
16	-	20960..23503 [-], 2544	Y4bN
17	-	23524..24513 [-], 990	AAA ATPase
18	res	24592..25176 [-], 585	TnpR
19	intI1	25449..26462 [-], 1014	IntI1	Integrase
20	aacA4	27211..27816 [+], 606	AacA4	AR
21	aadb	27886..28419 [+], 534	AadB	AR
22	dhfrA1	28488..28961 [+], 474	DhfrA1	AR
23	orfC	29055..29534 [+], 480	OrfC
24	qacEdelta1	29665..30012 [+], 348	QacEdelta1
25	sulI	30006..30845 [+], 840	SulI
26	blaVEB-6	32795..33694 [-], 900	VEB-6	AR
27	qacEdelta1	33943..34290 [+], 348	QacEdelta1
28	sulI	34284..35123 [+], 840	SulI	AR
29	orf513	35528..37069 [+], 1542	ISCR1
30	orfY	37779..38120 [-], 342	OrfY
31	tnpA	38312..38629 [+], 318	ISAba14, TnpA
32	aphA6	39562..40341 [+], 780	AphA6	AR
33	tnpA	40493..41518 [+], 1026	transposase
34	blaNDM-1	41619..42431 [+], 813	NDM-1	AR
35	bleMBL	42435..42800 [+], 366	bleMBL
36	trpF	42805..43464 [+], 660	TrpF
37	blaDHA-1	43164..44180 [-], 1017	DHA-1	AR
38	ampR	44291..45166 [+], 876	AmpR
39	qacEdelta1	45323..45763 [+], 441	QacEdelta1
40	sulI	45757..46596 [+], 840	SulI
41	tnpA	47001..48542 [+], 1542	ISCR1 TnpA
42	ampR	48950..49825 [+], 876	AmpR	AR
43	hybF	49829..50311 [-], 483	HybF
44	qacEdelta1	49982..50422 [+], 441	QacEdelta1
45	sul1	50416..51255 [+], 840	SulI	AR
46	tnpA	51830..54796 [-], 2967	TnpA transposition transposase
47	tnpR	54800..55360 [-], 561	TnpR
48	merR	55626..56060 [-], 435	MerR
49	merF	56132..56482 [+], 351	MerF
50	merP	56498..56773 [+], 276	MerP
51	merT	56776..57021 [+], 246	MerT
52	merA	57018..58664 [+], 1647	MerA
53	merD	58681..59046 [+], 366	MerD
54	merE	59043..59279 [+], 237	MerE
55	tnpR	59332..59946 [-], 615	TniR
56	tniQ	60007..61224 [-], 1218	TniQ
57	tniB	61221..62129 [-], 909	TniB
58	tniA	62132..63820 [-], 1689	TniA
59	-	64100..64729 [+], 630	hypothetical protein
60	hipB	65005..65262 [+], 258	HipB
61	hipA	65263..66576 [+], 1314	HipA
62	-	66980..67444 [+], 465	hypothetical protein

Flanking regions

Gene may contribute to site-specific recombination

Gene may play role in conjugative transfer

Gene may be involved in adaptative function

(1) Siebor E; de Curraize C; Amoureux L; Neuwirth C (2016). Mobilization of the Salmonella genomic island SGI1 and the Proteus genomic island PGI1 by the A/C2 plasmid carrying blaTEM-24 harboured by various clinical species of Enterobacteriaceae. J Antimicrob Chemother. 71(8):2167-70. [PudMed:27150396]

(2) Girlich D; Dortet L; Poirel L; Nordmann P (2015). Integration of the blaNDM-1 carbapenemase gene into Proteus genomic island 1 (PGI1-PmPEL) in a Proteus mirabilis clinical isolate. J Antimicrob Chemother. 70(1):98-102. [PudMed:25239462]