ICEberg

ICE
Gene list
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References

I. Information of ICE

ICEberg ID	861
Name	Tn6194-like
ICEO ID	ICEO_0000183
Organism	Clostridium difficile CII7
Size (bp)	28014
GC content [Genome] (%)	39.06
Insertion site	7 different instertion sites in Clostridium difficile ;tRNAArg(in Enterococcus faecalis)
Function	Antibiotic resistance genes: erm(B)
Species that ICE can be transferred to	Clostridium difficile; Enterococcus faecalis
Nucleotide Sequence	HG475346 (complete ICE sequence in this GenBank file)
Replicon	-
Coordinates	1..28014
Putative oriT region	-
Putative relaxase	coordinates: 6900..8096; Family: MOB_T

II. ICE interaction with IME/CIME/

The interaction information of Tn6194-like is not available.

The graph information of Tn6194-like components from HG475346

Complete gene list of Tn6194-like from HG475346
#	Gene	Coordinates [+/-], size (bp)	Product (GenBank annotation)	*Reannotation
1	-	302..3346 [+], 3045	cell surface protein
2	-	3579..3905 [+], 327	conjugative transposon protein
3	-	3921..4304 [+], 384	conjugative transposon protein, Tn916 orf22-like
4	-	4472..4879 [+], 408	transcriptional regulator
5	-	4895..5221 [+], 327	hypothetical protein
6	-	5322..6716 [+], 1395	conjugative transposon FtsK/SpoIIIE-like protein,Tn916 orf21-like	Orf21_Tn, T4SS component
7	-	6900..8096 [+], 1197	conjugative transposon replication initiation factor, Tn916 orf20-like	Relaxase, MOB_T Family
8	-	8109..8243 [+], 135	conjugative transposon protein
9	-	8244..8465 [+], 222	conjugative transposon protein, Tn916 orf19-like	Orf19_Tn, T4SS component
10	-	8669..9445 [+], 777	hypothetical protein
11	-	9530..9826 [+], 297	conjugative transposon protein
12	-	9961..10248 [+], 288	conjugative transposon protein, ArdA-like
13	-	10266..10769 [+], 504	antirestriction protein
14	-	10887..11285 [+], 399	conjugative transposon membrane protein, Tn916 orf17-like	Orf17_Tn, T4SS component
15	-	11263..13713 [+], 2451	conjugative transposon protein, Tn916 orf16-like	Orf16_Tn, T4SS component
16	-	13710..15908 [+], 2199	conjugative transposon protein, Tn916 orf15-like	Orf15_Tn, T4SS component
17	-	15905..16912 [+], 1008	conjugative transposon protein, Tn916 orf14-like	Orf14_Tn, T4SS component
18	-	16928..17839 [+], 912	conjugative transposon protein, Tn916 orf13-like	Orf13_Tn, T4SS component
19	-	17960..18337 [+], 378	transcriptional regulator
20	-	18338..19201 [+], 864	ATP binding cassette transporter protein
21	-	19198..19842 [+], 645	hypothetical protein
22	-	19855..20046 [+], 192	hypothetical protein
23	-	20080..20241 [+], 162	hypothetical protein
24	-	20308..20439 [+], 132	hypothetical protein
25	-	20547..20906 [-], 360	DNA-binding helix-turn-helix protein
26	-	21099..21308 [+], 210	transcriptionnal repressor
27	-	21325..21597 [+], 273	antitoxin
28	-	21599..21757 [+], 159	toxin
29	-	21809..22228 [+], 420	hypothetical protein
30	ermB	22275..23012 [+], 738	erythromycin ribosomal methylase	AR
31	-	23587..24423 [+], 837	putative ATPase
32	-	24871..25287 [+], 417	hypothetical protein
33	-	25294..25542 [+], 249	hypothetical protein
34	xis	25937..26194 [+], 258	excisionase
35	int	26213..27658 [+], 1446	integrase	Integrase

Gene may contribute to site-specific recombination

Element	No. of sequences	Download
Nucleotide sequences	1	Fasta
Proteins	35	Fasta

(1) Wasels F; Monot M; Spigaglia P; Barbanti F; Ma L; Bouchier C; Dupuy B; Mastrantonio P (2014). Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB. Microb Drug Resist. 20(6):555-60. [PubMed:25055190]

(2) Wasels F; Spigaglia P; Barbanti F; Mastrantonio P (2013). Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. J Med Microbiol. 62(Pt 9):1461-7. [PubMed:23741023]