I. Information of ICE
ICEberg ID814
Name ICESp2906 This ICE is derived from experimental literature
ICEO ID ICEO_0000732
OrganismStreptococcus pyogenes iB21
Size (bp)~53.0 kb
GC content [Genome] (%)-
Insertion site3' end of the conserved rum
FunctionAntibiotic resistance genes: tet(O)
Species that ICE can be transferred toStreptococcus pyogenes 24RF
Nucleotide SequenceFR691055 (partial ICE sequence)
Putative oriT region -
Putative relaxase -

II. ICE interaction with IME/CIME/

The interaction information of ICESp2906 is not available.

The graph information of ICESp2906 components from FR691055
Incomplete gene list of ICESp2906 from FR691055
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)
1rum285..1679 [+], 139523S rRNA m(5)U 1939 methyltransferase
2-1838..2122 [+], 285hypothetical protein
3-2137..2988 [+], 852Replication initiator protein A
4-2985..3836 [+], 852DNA replication protein
5-3833..4318 [+], 486hypothetical protein
6-4315..6099 [+], 1785TraG/TraD/VirD4 family bacterial conjugation protein
7-6153..6266 [+], 114hypothetical protein
8-6266..6577 [+], 312hypothetical protein
9-6581..6739 [+], 159hypothetical protein
10-6857..7075 [+], 219Transcriptional regulator
11-7079..7456 [+], 378hypothetical protein
12-7866..8303 [+], 438MarR bacterial repressor protein
13-8293..9600 [+], 1308MATE domain protein
14-9700..9813 [+], 114hypothetical protein
15erm(TR)10305..11036 [+], 732erythromycin resistance methylase
flank Flanking regions

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
(1) Morici E; Simoni S; Brenciani A; Giovanetti E; Varaldo PE; Mingoia M (2017). A new mosaic integrative and conjugative element from Streptococcus agalactiae carrying resistance genes for chloramphenicol (catQ) and macrolides [mef(I) and erm(TR)]. J Antimicrob Chemother. 72(1):64-67. [PubMed:27621174] experimental
(2) Giovanetti E; Brenciani A; Tiberi E; Bacciaglia A; Varaldo PE (2012). ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements. Antimicrob Agents Chemother. 56(1):591-4. [PubMed:21986826] experimental
experimental experimental literature