ICEberg
I. Information of ICE
ICEberg ID77
Name ICESe2 This ICE is derived from experimental literature
ICEO ID ICEO_0000176
OrganismStreptococcus equi subsp. equi 4047
Size (bp)63055
GC content [Genome] (%)30.6[41.28]
Insertion site-
FunctionNon-ribosomal peptide synthetase (NRPS) system and iron acquisition
Species that ICE can be transferred toStreptococcus equi
Nucleotide SequenceFM204883 (complete ICE sequence in this genome)
Replicon chromosome (2253793 bp, BioProject:30765) [NC_012471]
Genome coordinates1206317..1269371 
Putative oriT region -
Putative relaxase coordinates: 1234253..1235626; Locus tag: SEQ_1250;  Family:  MOBP


II. ICE interaction with IME/CIME/

The interaction information of ICESe2 is not available.



The graph information of ICESe2 components from FM204883
Complete gene list of ICESe2 from FM204883
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)		 *Reannotation 
1SEQ_12221201621..1202475 [-], 855putative GTPase protein
2SEQ_12231203068..1203700 [-], 633putative ABC transporter ATP-binding protein (pseudogene)
3SEQ_12251203702..1204571 [-], 870putative membrane protein (fragment)
4SEQ_12261204568..1204900 [-], 333putative cell surface-anchored thioredoxin (fragment)
5SEQ_12271204940..1205455 [+], 516putative transposase
6SEQ_12281205479..1206282 [+], 804putative transposase
7SEQ_12291206307..1207161 [-], 855putative conjugative transposon site-specific recombinase
8SEQ_12311207922..1208323 [-], 402putative DNA-binding protein
9SEQ_12321209169..1209414 [-], 246hypothetical protein
10eqbN1209536..1210441 [-], 906putative hydrolase
11eqbM1210463..1211527 [-], 1065putative oxidoreductase
12eqbL1211547..1213292 [-], 1746ABC transporter, ATP-binding membrane protein
13eqbK1213297..1215054 [-], 1758ABC transporter, ATP-binding membrane protein
14eqbJ1215077..1216453 [-], 1377ABC transporter, ATP-binding component
15eqbI1216467..1217138 [-], 672ABC transporter permease protein
16eqbH1217140..1217727 [-], 588ABC transporter permease protein
17eqbG1217717..1221535 [-], 3819equibactin nonribosomal peptide synthase protein
18eqbF1221519..1223645 [-], 2127putative thiazoline reductase
19eqbE1223642..1229713 [-], 6072equibactin nonribosomal peptide synthase protein
20eqbD1229728..1231311 [-], 1584putative salicylate-AMP-ligase
21eqbC1231320..1232003 [-], 684putative 4'-phosphopantetheinyl transferase
22eqbB1231990..1232739 [-], 750putative non-ribosomal peptide synthesis thioesterase type II
23eqbA1232968..1233348 [-], 381iron-dependent repressor proteinIntegrase 
24SEQ_12471233405..1233563 [-], 159putative conjugative transposon membrane protein
25SEQ_12491233885..1234253 [+], 369putative conjugative transposon mobilization protein
26SEQ_12501234253..1235626 [+], 1374putative conjugative transposon mobilization proteinRelaxase, MOBP Family
27SEQ_12511235736..1236221 [-], 486putative conjugative transposon membrane protein
28SEQ_12521236379..1237818 [-], 1440putative conjugative transposon single-strand binding protein
29SEQ_12531237819..1249746 [-], 11928putative conjugative transposon DNA recombination protein
30SEQ_12541249763..1250509 [-], 747conjugative transposon hypothetical protein
31SEQ_12551250551..1251102 [-], 552conjugative transposon hypothetical protein
32SEQ_12561251106..1252818 [-], 1713putative DNA topoisomerase
33SEQ_12571252990..1253832 [-], 843putative abortive infection protein
34SEQ_12581253825..1254418 [-], 594conjugative transposon hypothetical protein
35SEQ_12591254671..1256134 [-], 1464putative membrane protein
36SEQ_12601256112..1256399 [-], 288conjugative transposon hypothetical protein
37SEQ_12611256412..1258700 [-], 2289putative conjugative transposon membrane protein
38SEQ_12621258666..1259700 [-], 1035modification DNA methylase
39SEQ_12631259693..1262119 [-], 2427putative conjugal transfer protein
40SEQ_12641262130..1262540 [-], 411putative conjugative transposon membrane protein
41SEQ_12651262544..1263038 [-], 495putative conjugative transposon membrane protein
42SEQ_12661263111..1263929 [-], 819putative conjugative transposon membrane protein
43SEQ_12671263974..1264189 [-], 216putative conjugative transposon membrane protein
44SEQ_12681264547..1265143 [-], 597putative conjugative transposon exported protein
45SEQ_12691265140..1265814 [-], 675putative ABC transporter, ATP-binding protein
46SEQ_12701265815..1267983 [-], 2169putative membrane protein
47SEQ_12711268091..1268474 [-], 384putative bacteriocin
48SEQ_12721268752..1269399 [-], 648putative two-component sensor histidine kinase (fragment)
49SEQ_12731269450..1270130 [-], 681conserved hypothetical protein (fragment)
50SEQ_12741270226..1271191 [-], 966ParB-like nuclease protein
51SEQ_12751271184..1271960 [-], 777sporulation initiation inhibitor Soj homolog
52SEQ_12761272106..1273275 [-], 1170putative ABC transporter ATP-binding membrane protein (fragment)
 
flank Flanking regions

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins40Fasta
(1) Holden MT; Heather Z; Paillot R; Steward KF; Webb K; Ainslie F; Jourdan T; Bason NC; Holroyd NE; Mungall K; Quail MA; Sanders M; Simmonds M; Willey D; Brooks K; Aanensen DM; Spratt BG; Jolley KA; Maiden MC; Kehoe M; Chanter N; Bentley SD; Robinson C; Maskell DJ; Parkhill J; Waller AS (2009). Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens. PLoS Pathog. 5(3):e1000346. [PubMed:19325880]
(2) Heather Z; Holden MT; Steward KF; Parkhill J; Song L; Challis GL; Robinson C; Davis-Poynter N; Waller AS (2008). A novel streptococcal integrative conjugative element involved in iron acquisition. Mol Microbiol. 70(5):1274-92. [PubMed:18990191] experimental
 
experimental experimental literature

Genomics & Bioinformatics Group in MML, SJTU