ICEberg
I. Information of ICE
ICEberg ID60
Name ICEHin1056 This ICE is derived from experimental literature
ICEO ID ICEO_0000113
OrganismHaemophilus influenzae 1056
Size (bp)59393
GC content [Genome] (%)39.1
Insertion sitetRNA-Leu
FunctionTetracycline resistance
Species that ICE can be transferred toHaemophilus influenzae; Haemophilus parainfluenzae
Nucleotide SequenceAJ627386 (complete ICE sequence in this GenBank file)
Replicon-
Coordinates1..59393 
Putative oriT region -
Putative relaxase coordinates: 55497..57404; Locus tag: p1056.62;  Family:  MOBH


II. ICE interaction with IME/CIME/

The interaction information of ICEHin1056 is not available.



The graph information of ICEHin1056 components from AJ627386
Complete gene list of ICEHin1056 from AJ627386
#Gene Coordinates [+/-], size (bp) Product 
(GenBank annotation)		 *Reannotation 
1p1056.01141..977 [+], 837putative chromosome partitioning related protein
2p1056.02979..2334 [+], 1356replicative DNA helicase
3p1056.032327..4015 [+], 1689conserved hypothetical protein
4p1056.044015..4566 [+], 552conserved hypothetical protein
5p1056.054716..5939 [+], 1224conserved hypothetical protein
6p1056.066164..6919 [+], 756conserved hypothetical protein
7inrR6919..7407 [+], 489conserved hypothetical protein
8p1056.087654..8076 [+], 423single-strand binding protein
9p1056.098100..8621 [+], 522putative lipoprotein
10p1056.10c8837..9394 [-], 558hypothetical protein
11p1056.119485..11530 [+], 2046DNA topoisomerase III
12p1056.1212415..12843 [+], 429conserved hypothetical protein
13p1056.1312919..13599 [+], 681hypothetical protein
14p1056.1413738..14208 [+], 471putative DNA repair-like protein
15p1056.1514301..14780 [+], 480hypothetical protein
16p1056.1614720..15838 [+], 1119transposase for Tn10
17p1056.17c15964..16896 [-], 933transposase for insertion sequence element IS5
18cat17570..18211 [-], 642chloramphenicol acetyltransferase IIAR 
19p1056.19c18374..19321 [-], 948putative transposase, IS30 family
20p1056.2019653..20438 [+], 786putative transposase for insertion sequence element IS5
21p1056.2120822..21142 [+], 321putative monooxygenase
22p1056.2221024..21521 [+], 498conserved hypothetical protein
23p1056.2321529..22215 [+], 687Putative transcriptional regulator
24p1056.24c22193..22815 [-], 623Tetracycline repressor protein class B from transposon Tn10 (pseudogene)
25tetA22897..24102 [+], 1206putative tetracycline resistance proteinAR 
26tetC24215..24808 [-], 594putative transcriptional regulator
27tetD24896..25312 [+], 417putative regulatory protein
28tnp25322..26530 [-], 1209putative transposase
29p1056.2926582..26931 [+], 350conserved hypothetical protein (pseudogene)
30p1056.3026989..27753 [+], 765conserved hypothetical proteinTfc1, T4SS component 
31pilL27852..28481 [+], 630putative lipoprotein precursorTfc2, T4SS component 
32p1056.3228485..29225 [+], 741putative exported protein precursorTfc3, T4SS component 
33p1056.3329204..29962 [+], 759putative exported protein precursorTfc4, T4SS component 
34p1056.3429978..30484 [+], 507putative exported protein precursorTfc5, T4SS component 
35p1056.3530481..32730 [+], 2250conserved hypothetical proteinTfc6, T4SS component 
36p1056.3632741..33049 [+], 309conserved hypothetical proteinTfc7, T4SS component 
37p1056.3733049..33735 [+], 687Putative membrane proteinTfc8, T4SS component 
38p1056.3833866..34216 [+], 351Putative exported protein precursorTfc9, T4SS component 
39p1056.3934485..34886 [+], 402putative membrane proteinTfc10, T4SS component 
40p1056.4034906..35277 [+], 372putative membrane proteinTfc11, T4SS component 
41p1056.4135289..35918 [+], 630putative exported protein precursorTfc12, T4SS component 
42p1056.4235937..36806 [+], 870conserved hypothetical proteinTfc13, T4SS component 
43p1056.4336817..38217 [+], 1401putative exported protein precursorTfc14, T4SS component 
44p1056.4438227..38634 [+], 408putative lipoprotein precursorTfc15, T4SS component 
45p1056.4538650..41520 [+], 2871conserved hypothetical proteinTfc16, T4SS component 
46p1056.4641528..41935 [+], 408conserved hypothetical proteinTfc17, T4SS component 
47p1056.4741945..42268 [+], 324hypothetical membrane proteinTfc18, T4SS component 
48p1056.4842277..43770 [+], 1494Putative membrane proteinTfc19, T4SS component 
49p1056.49c43826..44155 [-], 330hypothetical membrane proteinTfc20, T4SS component 
50p1056.50c44575..44982 [-], 408hypothetical exported proteinTfc21, T4SS component 
51p1056.51c44998..46998 [-], 2001putative exported protein precursorTfc22, T4SS component 
52p1056.52c47013..47939 [-], 927putative exported proteinTfc23, T4SS component 
53p1056.53c47951..48388 [-], 438conserved hypothetical proteinTfc24, T4SS component 
54p1056.5448763..49125 [+], 363hypothetical membrane protein
55p1056.5549210..49443 [+], 234conserved hypothetical protein
56p1056.5649985..50890 [+], 906putative antirestriction protein
57blaTEM1D50985..51845 [-], 861beta-lactamase TEM precursorAR 
58p1056.58c52028..52585 [-], 558transposon Tn3 resolvase
59p1056.5952884..53201 [+], 318hypothetical protein
60p1056.6053491..54189 [+], 699putative DNA-binding protein
61p1056.61c54706..55260 [-], 555hypothetical protein
62p1056.6255497..57404 [+], 1908conserved hypothetical proteinRelaxase, MOBH Family
63p1056.6357495..58307 [+], 813Putative site-specific recombinaseIntegrase 
64p1056.64c58302..59078 [-], 777conserved phage-related hypothetical protein
 

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins62Fasta
(1) Seth-Smith HM; Fookes MC; Okoro CK; Baker S; Harris SR; Scott P; Pickard D; Quail MA; Churcher C; Sanders M; Harmse J; Dougan G; Parkhill J; Thomson NR (2012). Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae. J Bacteriol. 194(6):1494-504. [PubMed:22247511] in_silico
(2) Saha SK; Darmstadt GL; Baqui AH; Islam N; Qazi S; Islam M; El Arifeen S; Santosham M; Black RE; Crook DW (2008). Direct detection of the multidrug resistance genome of Haemophilus influenzae in cerebrospinal fluid of children: implications for treatment of meningitis. Pediatr Infect Dis J. 27(1):49-53. [PubMed:18162938] experimental
(3) Juhas M; Power PM; Harding RM; Ferguson DJ; Dimopoulou ID; Elamin AR; Mohd-Zain Z; Hood DW; Adegbola R; Erwin A; Smith A; Munson RS; Harrison A; Mansfield L; Bentley S; Crook DW (2007). Sequence and functional analyses of Haemophilus spp. genomic islands. Genome Biol. 8(11):R237. [PubMed:17996041] in_silico
(4) Dimopoulou ID; Kartali SI; Harding RM; Peto TE; Crook DW (2007). Diversity of antibiotic resistance integrative and conjugative elements among haemophili. J Med Microbiol. 56(Pt 6):838-46. [PubMed:17510272] experimental
(5) Mohd-Zain Z; Turner SL; Cerdeno-Tarraga AM; Lilley AK; Inzana TJ; Duncan AJ; Harding RM; Hood DW; Peto TE; Crook DW (2004). Transferable antibiotic resistance elements in Haemophilus influenzae share a common evolutionary origin with a diverse family of syntenic genomic islands. J Bacteriol. 186(23):8114-22. [PubMed:15547285] experimental
 
experimental experimental literature
in_silico in silico analysis literature

Genomics & Bioinformatics Group in MML, SJTU