ICEberg

ICE
Gene list
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References

I. Information of ICE

ICEberg ID	409
Name	ICESp1108
ICEO ID	ICEO_0000157
Organism	Streptococcus pyogenes C1
Size (bp)	45456
GC content [Genome] (%)	31.07
Insertion site	3' end of the rum gene
Function	spectinomycin, erythromycin, tetronasin resistance
Species that ICE can be transferred to	-
Nucleotide Sequence	FR691054 (complete ICE sequence in this GenBank file)
Replicon	-
Coordinates	1694..47149
Putative oriT region	-
Putative relaxase	coordinates: 38857..40188; Gene: ORF32; Family: MOB_P

II. ICE interaction with IME/CIME/

The interaction information of ICESp1108 is not available.

The graph information of ICESp1108 components from FR691054

Complete gene list of ICESp1108 from FR691054
#	Gene	Coordinates [+/-], size (bp)	Product (GenBank annotation)	*Reannotation
1	rum	332..1720 [+], 1389	23S rRNA m(5)U 1939 methyltransferase
2	ORF1	1951..2586 [+], 636	replication initiator protein
3	ORF2	2583..3410 [+], 828	DNA replication protein
4	ORF3	3403..3888 [+], 486	hypothetical protein
5	ORF4	3885..4619 [+], 735	phage antirepressor protein
6	ORF5	4612..6408 [+], 1797	TraG/TraD/VirD4 bacterial conjugation protein
7	ORF6	6427..6702 [+], 276	hypothetical protein
8	ORF7	6814..7182 [+], 369	hypothetical protein
9	ORF8	7529..7822 [+], 294	hypothetical protein
10	ORF9	8045..8356 [+], 312	hypothetical protein
11	ORF10	8358..8573 [+], 216	hypothetical protein
12	ORF11	8584..9447 [+], 864	hypothetical protein
13	ORF12	9457..9747 [+], 291	hypothetical protein
14	ORF13	9749..10159 [+], 411	bacitracin resistance protein
15	ORF14	10050..12470 [+], 2421	type IV secretory pathway protein VirB4	PrgJ, T4SS component
16	ORF15	12478..15057 [+], 2580	NlpC/P60 family protein	Orf14_Tn, T4SS component
17	ORF16	15298..16881 [+], 1584	amine oxidase
18	ORF17	16896..17756 [+], 861	hypothetical protein
19	ORF18	18053..18256 [+], 204	hypothetical protein
20	ORF19	18492..19232 [+], 741	hypothetical protein
21	ORF20	19354..21087 [+], 1734	DNA topoisomerase IA
22	ORF21	21080..22045 [+], 966	C-5 cytosine specific DNA methylase
23	ORF22	22032..29675 [+], 7644	superfamily II DNA/RNA helicase
24	ORF23	29719..30375 [+], 657	hypothetical protein
25	ORF24	30927..31559 [+], 633	transcriptional regulator, TetR family
26	ORF25	31644..32525 [+], 882	tetronasin resistance ATP-binding protein
27	ORF26	32458..34164 [+], 1707	tetronasin resistance transmembrane protein
28	ORF27	34745..34951 [-], 207	hypothetical protein
29	erm(TR)	34898..35629 [+], 732	erythromycin resistance methylase	AR
30	ORF29	35846..36370 [+], 525	spectinomycin phosphotransferase
31	ORF30	36416..36535 [+], 120	hypothetical protein
32	ORF31	37228..38451 [+], 1224	transposase IS116/IS110/IS902 family protein
33	ORF32	38857..40188 [-], 1332	relaxase/mobilization protein	Relaxase, MOB_P Family
34	ORF33	40190..40648 [-], 459	hypothetical protein
35	ORF34	40717..41811 [-], 1095	RhuM
36	ORF35	41792..42274 [-], 483	cation transporter family protein
37	ORF36	42283..42831 [-], 549	Zn-dependent peptidase
38	ORF37	42840..43241 [-], 402	trascriptional regulator Cro/CI family protein
39	ORF38	43376..43951 [+], 576	hypothetical protein
40	ORF39	44221..44631 [+], 411	RNA polymerase sigma-70 region 4
41	ORF40	45362..47149 [+], 1788	putative recombinase	Integrase
42	pnp	47452..47850 [+], 399	phosphorylase

Flanking regions

Element	No. of sequences	Download
Nucleotide sequences	1	Fasta
Proteins	40	Fasta

(1) Brenciani A; Tiberi E; Bacciaglia A; Petrelli D; Varaldo PE; Giovanetti E (2011). Two distinct genetic elements are responsible for erm(TR)-mediated erythromycin resistance in tetracycline-susceptible and tetracycline-resistant strains of Streptococcus pyogenes. Antimicrob Agents Chemother. 55(5):2106-12. [PubMed:21343455]

experimental literature