I. Information of ICE

ICEberg ID	190
Name	10270-RD.1
Organism	Streptococcus pyogenes MGAS10270
Size (bp)	15367
GC content [Genome] (%)	30.99[38.43]
Insertion site	-
Function	SrtA required for cell wall anchoring of protein A as well as virulence
Species that ICE can be transferred to	-
Nucleotide Sequence	CP000260 (complete ICE sequence in this genome)
Replicon	chromosome (1928252 bp, BioProject:16364) [NC_008022]
Genome coordinates	871808..887174
Putative oriT region	-
Putative relaxase	coordinates: 872871..873083; Locus tag: MGAS10270_Spy0914;  Family:  MOBP

II. ICE interaction with IME/CIME/

The interaction information of 10270-RD.1 is not available.

The graph information of 10270-RD.1 components from CP000260
Complete gene list of 10270-RD.1 from CP000260
#	Gene	Coordinates [+/-], size (bp)	Product  (GenBank annotation)	*Reannotation
1	MGAS10270_Spy0906	867243..868703 [+], 1461	Xaa-His dipeptidase
2	thdF	868771..870147 [-], 1377	tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
3	rplJ	870419..870982 [+], 564	LSU ribosomal protein L10P
4	rplL	871032..871412 [+], 381	LSU ribosomal protein L12P (L7/L12)
5	MGAS10270_Spy0910	871808..871948 [+], 141	hypothetical protein
6	MGAS10270_Spy0911	871942..872310 [+], 369	hypothetical protein
7	MGAS10270_Spy0912	872327..872431 [+], 105	hypothetical protein
8	MGAS10270_Spy0913	872481..872813 [+], 333	DNA-cytosine methyltransferase
9	MGAS10270_Spy0914	872871..873083 [+], 213	Relaxase	Relaxase, MOBP Family
10	MGAS10270_Spy0915	873126..873338 [+], 213	Relaxase
11	srtI	873604..874299 [+], 696	Relaxase
12	srtR	874450..875136 [+], 687	Lantibiotic biosynthesis two-component response regulator
13	srtK	875114..876475 [+], 1362	Lantibiotic biosynthesis sensor protein
14	srtA	876632..876772 [+], 141	Lantibiotic srtA precursor
15	srtT	876887..878677 [+], 1791	Lantibiotic transport permease protein / Lantibiotic transport ATP-binding protein
16	MGAS10270_Spy0921	878649..879905 [+], 1257	Lanthionine synthetase
17	MGAS10270_Spy0922	879924..882890 [+], 2967	serine/threoninedehydratase
18	srtF	882839..883585 [+], 747	Lantibiotic transport ATP-binding protein
19	srtE	883591..884340 [+], 750	Lantibiotic transport permease protein
20	srtG	884343..885065 [+], 723	Lantibiotic transport permease protein
21	MGAS10270_Spy0926	885257..885424 [+], 168	Transcriptional regulator, Cro/CI family
22	MGAS10270_Spy0928	885571..885873 [-], 303	hypothetical protein
23	MGAS10270_Spy0927	885760..885984 [+], 225	hypothetical protein
24	MGAS10270_Spy0929	885987..886118 [+], 132	DNA integration/recombination/inversion protein
25	MGAS10270_Spy0930	886140..886361 [+], 222	DNA integration/recombination/inversion protein
26	MGAS10270_Spy0931	886434..886655 [+], 222	DNA integration/recombination/inversion protein
27	MGAS10270_Spy0932	886686..887174 [+], 489	DNA integration/recombination/inversion protein	Integrase
28	dacA1	887212..888567 [+], 1356	D-alanyl-D-alanine serine-type carboxypeptidase
29	MGAS10270_Spy0934	888683..889645 [-], 963	Polysaccharide deacetylase
30	MGAS10270_Spy0935	889733..889888 [+], 156	hypothetical protein
31	folC1	889878..891254 [+], 1377	Folylpolyglutamate synthase / Dihydrofolate synthase
32	folE	891265..891873 [+], 609	GTP cyclohydrolase I

Flanking regions

(1) Beres SB; Musser JM (2007). Contribution of exogenous genetic elements to the group A Streptococcus metagenome. PLoS One. 2(8):e800. [PubMed:17726530]