I. Information of ICE

ICEberg ID	182
Name	10750-RD.1
Organism	Streptococcus pyogenes MGAS10750
Size (bp)	15415
GC content [Genome] (%)	31[38.32]
Insertion site	-
Function	SrtA required for cell wall anchoring of protein A as well as virulence
Species that ICE can be transferred to	-
Nucleotide Sequence	CP000262 (complete ICE sequence in this genome)
Replicon	chromosome (1937111 bp, BioProject:16366) [NC_008024]
Genome coordinates	902811..918225
Putative oriT region	-
Putative relaxase	coordinates: 903897..904109; Locus tag: MGAS10750_Spy0949;  Family:  MOBP

II. ICE interaction with IME/CIME/

The interaction information of 10750-RD.1 is not available.

The graph information of 10750-RD.1 components from CP000262
Complete gene list of 10750-RD.1 from CP000262
#	Gene	Coordinates [+/-], size (bp)	Product  (GenBank annotation)	*Reannotation
1	MGAS10750_Spy0941	898246..899706 [+], 1461	Xaa-His dipeptidase
2	thdF	899774..901150 [-], 1377	tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase
3	rplJ	901423..901986 [+], 564	LSU ribosomal protein L10P
4	rplL	902036..902416 [+], 381	LSU ribosomal protein L12P (L7/L12)
5	MGAS10750_Spy0945	902811..902972 [+], 162	hypothetical protein
6	MGAS10750_Spy0946	902966..903334 [+], 369	hypothetical protein
7	MGAS10750_Spy0947	903351..903455 [+], 105	hypothetical protein
8	MGAS10750_Spy0948	903505..903864 [+], 360	DNA-cytosine methyltransferase
9	MGAS10750_Spy0949	903897..904109 [+], 213	Relaxase	Relaxase, MOBP Family
10	MGAS10750_Spy0950	904152..904364 [+], 213	Relaxase
11	MGAS10750_Spy0951	904629..904940 [+], 312	Relaxase
12	srtI	905009..905326 [+], 318	Relaxase
13	srtR	905477..906163 [+], 687	Lantibiotic biosynthesis two-component response regulator
14	srtK	906141..907502 [+], 1362	Lantibiotic biosynthesis sensor protein
15	srtA	907659..907799 [+], 141	Lantibiotic srtA precursor
16	srtT	907914..909704 [+], 1791	Lantibiotic transport permease protein / Lantibiotic transport ATP-binding protein
17	MGAS10750_Spy0957	909676..910932 [+], 1257	Lanthionine synthetase
18	MGAS10750_Spy0958	910951..913917 [+], 2967	serine/threoninedehydratase
19	srtF	913866..914612 [+], 747	Lantibiotic transport ATP-binding protein
20	srtE	914618..915367 [+], 750	Lantibiotic transport permease protein
21	srtG	915370..916092 [+], 723	Lantibiotic transport permease protein
22	MGAS10750_Spy0962	916284..916502 [+], 219	Transcriptional regulator, Cro/CI family
23	MGAS10750_Spy0964	916611..916913 [-], 303	hypothetical protein
24	MGAS10750_Spy0963	916800..917024 [+], 225	hypothetical protein
25	MGAS10750_Spy0965	917027..917158 [+], 132	DNA integration/recombination/inversion protein
26	MGAS10750_Spy0966	917485..917706 [+], 222	DNA integration/recombination/inversion protein
27	MGAS10750_Spy0967	917737..918225 [+], 489	DNA integration/recombination/inversion protein	Integrase
28	dacA1	918263..919618 [+], 1356	D-alanyl-D-alanine serine-type carboxypeptidase
29	MGAS10750_Spy0969	919735..920697 [-], 963	Polysaccharide deacetylase
30	MGAS10750_Spy0970	920785..920940 [+], 156	hypothetical protein
31	folC1	920930..922306 [+], 1377	Folylpolyglutamate synthase / Dihydrofolate synthase
32	folE	922317..922919 [+], 603	GTP cyclohydrolase I

Flanking regions

(1) Beres SB; Musser JM (2007). Contribution of exogenous genetic elements to the group A Streptococcus metagenome. PLoS One. 2(8):e800. [PubMed:17726530]