| Effector Protein ID: 51473566 |
 T4SS name [ID] | VirB [498] |
| Gene symbol | - |
| Locus tag | RT0362 |
| Strain | Rickettsia typhi str. Wilmington |
| Replicon | chromosome [GenBank: NC_006142] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 458514..459878 [+] |
| Product | Sec7-domain-containing protein |
| Effector type | Protein |
| Descripton | RalF |
| T4CP requirement | T4CP Depedent |
| Target/Effection | RalF facilitates bacterial invasion. |
| UniProt ID | Q68X01 |
| KEGG ID | rty:RT0362 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Sec7 [PF01369], Evalue: 1.2e-49, Aligned region: 4-190 RalF_SCD [PF18248], Evalue: 4.2e-39, Aligned region: 196-346 |
| Protein Sequence: 454 a.a. [Download] |
| >gi|51473566|ref|YP_067323.1| Sec7-domain-containing protein [Rickettsia typhi str. Wilmington] MDSLLKNEVIKLFNDKQKSGITRIKKWCADNNKDFIEETAKFFYEEKSNLNLEFVGDYLGTDGVDNQKVL ESFTKKFDFKDKDYLESLRRFLQSFKLPGEAQKIDRLVESFGTHYYEQNLNIDINSKDAAYILAYQAIML NTDLHNPSIAKSKKMTFEQLKNNLKGTNENKNFNDNFLKKIYDEIEAKPFKLNFVDSSPGYQINNISSQN DKVFKQLNQFLEEKRNIQNIFPKLQNNNLTIEFKNAKTFLNKFTGYKGNVIIQDEQCGKAEIQVYKPSIF SRWFLGEKSKIIIQPLREDGKQPSEQSLELAAQITASFETEVTSIKATYDYLKEDLKSKYDNIRNAKQEL ERISTIAEGHKNIKTEVVYQINQPVKNSVAVSTISVVSPMSKDDIHINPPPLPLPKSIPNVVKKAAKDIS KQIPQERDNHKEELSKVLEVQRKKIDKQNSGRVV |
| - |
| Nucleotide Sequence: 1365 bp [Download] |
| >gi|51473215|ref|NC_006142.1|:458514-459878 Rickettsia typhi str. Wilmington, complete genome ATGGATTCATTACTAAAAAACGAAGTAATTAAACTGTTTAATGATAAGCAAAAAAGTGGAATCACAAGAA TTAAAAAATGGTGTGCTGATAATAATAAAGATTTTATAGAAGAAACTGCTAAATTTTTTTATGAAGAAAA AAGTAATTTGAATTTAGAATTTGTAGGCGATTATCTTGGTACAGATGGGGTTGATAATCAAAAAGTATTA GAAAGTTTTACTAAGAAATTTGATTTTAAAGACAAAGATTATTTAGAAAGTTTACGTAGGTTTTTACAAT CATTTAAATTACCGGGCGAAGCTCAAAAAATCGATAGGTTAGTTGAAAGTTTTGGAACACATTATTATGA ACAAAATTTAAACATTGACATAAACAGTAAAGATGCTGCATATATATTAGCTTACCAAGCAATTATGCTT AATACCGATTTACATAATCCGAGTATTGCAAAATCGAAAAAAATGACCTTTGAGCAATTAAAGAATAATT TAAAAGGTACTAATGAAAATAAAAATTTTAATGATAATTTTTTAAAAAAGATATATGACGAAATAGAGGC GAAACCTTTTAAATTAAATTTTGTTGATAGTAGTCCTGGTTATCAGATAAATAATATAAGTTCGCAAAAT GATAAAGTTTTTAAACAATTAAATCAATTTTTAGAAGAAAAGAGAAATATTCAAAACATCTTTCCTAAAT TACAAAATAATAATTTAACGATAGAATTTAAAAATGCTAAAACATTTCTTAATAAGTTTACCGGTTACAA AGGAAATGTAATCATTCAGGATGAGCAATGCGGTAAAGCAGAAATACAAGTATATAAACCAAGTATATTT TCAAGATGGTTTTTAGGTGAAAAGTCTAAAATCATAATTCAGCCTTTACGTGAAGACGGGAAACAACCTT CAGAACAATCATTGGAATTAGCTGCTCAAATTACTGCAAGCTTTGAAACTGAAGTAACATCTATTAAGGC AACTTATGATTATTTAAAGGAAGATTTAAAGAGCAAGTATGATAATATTAGAAATGCTAAACAAGAATTA GAAAGAATTAGCACTATTGCAGAAGGACATAAAAATATTAAAACAGAAGTTGTATATCAAATAAATCAAC CAGTAAAAAATTCTGTAGCTGTTAGTACTATATCAGTTGTGTCGCCAATGTCTAAGGATGATATTCATAT TAATCCCCCACCATTACCACTTCCTAAATCAATTCCAAATGTTGTAAAAAAAGCGGCGAAGGATATTAGT AAACAAATACCTCAAGAAAGAGATAATCATAAAGAAGAACTTTCAAAAGTTCTGGAGGTACAAAGAAAAA AAATAGACAAGCAAAATTCAGGGAGAGTAGTATAA |
| Reference |
(1) Rennoll-Bankert KE et al. (2015). Which Way In? The RalF Arf-GEF Orchestrates Rickettsia Host Cell Invasion. PLoS Pathog. 11(8):e1005115. [PudMed:26291822] 
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| experimental literature |