| Effector Protein ID: 212213067 |
 T4SS name [ID] | Dot/Icm [159] |
| Gene symbol | - |
| Locus tag | CbuG_1564 |
| Strain | Coxiella burnetii CbuG_Q212 |
| Replicon | chromosome [GenBank: NC_011527] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1526684..1527238 [+] |
| Product | ankyrin repeat protein |
| Effector type | Protein |
| Descripton | AnkF |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Inhibits apoptosis |
| UniProt ID | B6J1N0 |
| KEGG ID | cbg:CbuG_1564 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 1.2e-17, Aligned region: 17..95 Ank_5 [PF13857], Evalue: 5.7e-15, Aligned region: 71..94 Ank [PF00023], Evalue: 7.5e-15, Aligned region: 74..95 Ank_4 [PF13637], Evalue: 1e-12, Aligned region: 45..94 |
| Protein Sequence: 184 a.a. [Download] |
| >gi|212213067|ref|YP_002304003.1| ankyrin repeat protein [Coxiella burnetii CbuG_Q212] MRQREINDEAMQRLFEACIYNAPGEMERILQRTDIDPNQKYEDKTPLEIASLEGYRDIVELLIEHPLVVD SREGYQALHFACERGHVEIAELLLGKVVQRRGRVASKLLANLLYTTCESGKLEIVKLLIEGYARDPFIAL ERTEYGIPLAIAAARNFQPIVDYFWEQGVPYLEEEKRNNRGFQR |
| - |
| Nucleotide Sequence: 555 bp [Download] |
| >gi|212211668|ref|NC_011527.1|:1526684-1527238 Coxiella burnetii CbuG_Q212 chromosome, complete genome ATGAGACAGCGTGAAATTAATGATGAAGCTATGCAGCGGCTATTTGAAGCTTGTATCTATAATGCCCCCG GCGAGATGGAAAGGATATTGCAAAGGACGGACATTGATCCCAATCAAAAATATGAAGATAAAACACCACT CGAAATCGCTTCCTTGGAAGGTTATCGAGATATTGTGGAACTTTTAATTGAACACCCTCTCGTAGTCGAC TCAAGAGAGGGGTATCAAGCACTCCATTTCGCTTGTGAGCGTGGTCACGTAGAGATAGCAGAACTTTTAT TGGGTAAGGTAGTACAGCGGCGTGGGCGAGTTGCTTCAAAGCTATTGGCCAACCTTCTATACACCACCTG CGAATCAGGAAAGCTTGAAATTGTAAAACTATTAATTGAGGGATACGCTAGAGATCCCTTTATTGCTTTA GAGCGGACCGAATACGGCATCCCTCTGGCCATTGCAGCCGCCCGCAACTTTCAACCTATCGTCGATTACT TTTGGGAACAAGGCGTACCTTATCTGGAAGAAGAAAAAAGAAATAATCGCGGCTTCCAGCGGTAG |
| Reference |
| (1) McDonough JA; Newton HJ; Roy CR (2012). Coxiella burnetii Secretion Systems. Adv Exp Med Biol. 984:171-97. [PudMed:22711632] |
(2) Voth DE; Howe D; Beare PA; Vogel JP; Unsworth N; Samuel JE; Heinzen RA (2009). The Coxiella burnetii ankyrin repeat domain-containing protein family is heterogeneous, with C-terminal truncations that influence Dot/Icm-mediated secretion. J Bacteriol. 191(13):4232-42. [PudMed:19411324] 
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(3) Pan X; Luhrmann A; Satoh A; Laskowski-Arce MA; Roy CR (2008). Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science. 320(5883):1651-4. [PudMed:18566289] 
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| experimental literature |
| in silico analysis literature |