| Effector Protein ID: 157828792 |
 T4SS name [ID] | VirB [489] |
| Gene symbol | - |
| Locus tag | A1G_05165 |
| Strain | Rickettsia rickettsii str. 'Sheila Smith' |
| Replicon | chromosome [GenBank: NC_009882] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 869777..871627 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | Rickettsia ankyrin repeat protein 2 (RARP-2) |
| T4CP requirement | T4CP Depedent |
| Target/Effection | RARP-2 is secreted by a type IV secretion system into the cytosol of the host cell, where it interacts with and manipulates the structure of the endoplasmic reticulum. |
| UniProt ID | A0A0H3AY85 |
| KEGG ID | rri:A1G_05165 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 616 a.a. [Download] |
| >gi|157828792|ref|YP_001495034.1| hypothetical protein A1G_05165 [Rickettsia rickettsii str. 'Sheila Smith'] MQKILFKGPNISMKNENPDIKEIKTLADLPSGTGSEYFINVHGSEFFCKPTDLGLWGKIKSYFMPESSYL LMNIFSDEGTTPVLDITLLNKIQNNTTANQCNIVHIFSCHSGAAQHHLDWIQGNIVLCTYNKASDANIMR LAQNNYDARTKNNSLLIEYIRDHFHLLVASDFSISYKLDNQIYSFSLSANKIKQMKSIEELPAFLHKEYK AFVKFYENIHAKYHESYPEIFNLNIETKPKELTYDDLIKVFSRALTLETYNFNKFSLSKIETMLNQKGLC TDTSIRHAIEHGNSELLICLLNYGNTKVSTYTLDKAIEKGDLAILKAVLEHSTTKIEPYTLDKAIEKGDL AILKAVLEHSTTKIESYNLDKAIEEGDLAILKAVLEHSTTKIEPYTLDKAIEKGDLAILKAVLEHSTTKI ESYNLDKAIEEGDLAILKAVLEHSTTKIEPYNLGKVIEKGDLAILKAVLEHSTTKIELYNLGKAIEKGDL AILKAILEHSTTKIELYNLGKAIEKGDLAILKAVLEHSTTKIALYNLGEAIEEGDLAILKAVLEHSTIEV GSSNIYTAEETHNLDVIELVKKYSTINTITSEENTIDTTLTVVEEVPALGEGTEGV |
| - |
| Nucleotide Sequence: 1851 bp [Download] |
| >gi|157827862|ref|NC_009882.1|:c871627-869777 Rickettsia rickettsii str. 'Sheila Smith' chromosome, complete genome ATGCAAAAAATATTGTTTAAAGGCCCGAATATAAGTATGAAAAATGAAAATCCTGATATCAAGGAAATAA AAACCTTAGCTGACTTACCTTCAGGTACAGGTAGTGAATATTTTATAAATGTACATGGATCAGAGTTTTT CTGTAAACCTACTGATTTAGGTTTATGGGGAAAAATTAAATCATATTTTATGCCTGAGTCTTCTTACTTA TTAATGAATATATTTTCTGATGAAGGTACAACTCCTGTATTAGATATTACACTACTTAATAAGATACAAA ATAATACCACTGCAAATCAATGTAATATTGTTCATATATTTTCTTGTCATTCAGGAGCCGCTCAACATCA TTTAGATTGGATACAGGGCAACATTGTGTTATGCACTTATAATAAGGCCAGCGATGCAAATATTATGCGA TTAGCTCAAAATAATTACGATGCTAGAACAAAAAATAACTCCTTATTGATTGAATATATAAGAGATCATT TTCATCTATTAGTAGCATCAGATTTTAGTATAAGCTATAAATTAGACAATCAAATTTATAGTTTTTCTTT AAGTGCTAATAAAATCAAACAGATGAAAAGCATAGAGGAGTTGCCGGCTTTTCTACATAAAGAATATAAA GCTTTTGTAAAATTTTATGAAAATATTCATGCGAAATATCATGAATCATATCCTGAAATATTTAACTTAA ATATAGAAACAAAGCCGAAAGAATTAACATACGATGACTTAATCAAGGTATTTAGTAGAGCTTTAACCTT AGAAACATATAATTTTAATAAATTTTCTTTAAGCAAGATAGAGACTATGTTAAATCAGAAAGGATTATGT ACTGATACTAGTATAAGGCACGCTATAGAGCACGGGAATTCTGAACTATTAATTTGTTTACTTAATTATG GTAATACTAAAGTCAGTACCTATACTCTTGATAAGGCTATAGAGAAAGGTGATTTAGCTATTCTAAAAGC TGTACTTGAGCATAGTACTACAAAAATAGAACCATATACTCTTGATAAGGCTATAGAGAAAGGTGATTTA GCTATTCTAAAAGCTGTACTTGAGCATAGTACTACAAAAATAGAATCATATAATCTTGATAAGGCTATAG AGGAAGGTGATTTAGCTATTCTAAAAGCTGTACTTGAGCATAGTACTACAAAAATAGAACCATATACTCT TGATAAGGCTATAGAGAAAGGTGATTTAGCTATTCTAAAAGCTGTACTTGAGCATAGTACTACAAAAATA GAATCATATAATCTTGATAAGGCTATAGAGGAAGGTGATTTAGCTATTCTAAAAGCTGTACTTGAGCATA GTACTACAAAAATAGAACCATATAATCTTGGTAAGGTTATAGAGAAAGGTGATTTAGCTATTCTAAAAGC TGTACTTGAGCATAGTACTACAAAAATAGAATTATATAATCTTGGTAAGGCTATAGAGAAAGGTGATTTA GCTATTCTAAAAGCTATACTTGAGCATAGTACTACAAAAATAGAATTATATAATCTTGGTAAGGCTATAG AGAAAGGTGATTTAGCTATTCTAAAAGCTGTACTTGAGCATAGTACTACAAAAATAGCATTATATAATCT TGGTGAGGCTATAGAGGAAGGTGATTTAGCTATTCTAAAAGCTGTACTTGAGCATAGTACTATAGAGGTA GGTAGCTCTAATATTTATACGGCAGAAGAGACGCATAATTTAGACGTTATCGAATTAGTAAAAAAATATT CTACTATAAATACTATTACATCTGAAGAAAACACTATAGATACAACACTTACTGTGGTAGAAGAAGTACC GGCATTAGGAGAGGGGACAGAGGGAGTATAA |
| Reference |
(1) Lehman SS et al. (2018). The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum. MBio. 9(3):e00975-18. [PudMed:29946049] 
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| experimental literature |