SecReT4

T4SS
References

T4SS ID	477
Strain	Neorickettsia risticii str. Illinois
Replicon	chromosome [Browse all T4SS(s) in this replicon]
Accession	NC_013009
Location	189561..190992; 676486..682248; 701053..254797112; 777907..792487
Name	VirB
Function	NA
Classification	Type IVA; Type P
Experimental investigation has been performed on this T4SS.

T4SS components

Component	VirB1	VirB2	VirB3	VirB4	VirB5	VirB6	VirB7	VirB8	VirB9
Number	0	2	1	2	0	4	0	2	2
Component	VirB10	VirB11	VirD4
Number	1	1	1

The information of T4SS components from NC_013009
Region 1: 189561..190992

#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	NRI_0199 (priA)	185496..187625 [+], 2130	254796593	primosomal protein N'
2	NRI_0200	187830..188939 [+], 1110	254796594	hypothetical protein
3	NRI_0201	188945..189568 [-], 624	254796595	exopolysaccharide synthesis protein
4	NRI_0202	189561..190361 [-], 801	254796596	type IV secretion system protein VirB9	VirB9
5	NRI_0203	190345..190992 [-], 648	254796597	type IV secretion system protein VirB8	VirB8
6	NRI_0204 (grpE)	191083..191637 [+], 555	254796598	co-chaperone GrpE
7	NRI_0205 (trpS)	191678..192658 [+], 981	254796599	tryptophanyl-tRNA synthetase
8	NRI_0206	192676..192927 [+], 252	254796600	hypothetical protein
9	NRI_0207 (rplT)	192941..193294 [+], 354	254796601	50S ribosomal protein L20
10	NRI_0208 (pheS)	193291..194268 [+], 978	254796602	phenylalanyl-tRNA synthetase, alpha subunit
11	NRI_0209 (rpiB)	194304..194744 [+], 441	254796603	ribose 5-phosphate isomerase B
12	NRI_0210 (glyA)	194744..195985 [+], 1242	254796604	serine hydroxymethyltransferase

Region 2: 676486..682248

#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	NRI_0708 (ppa)	672658..673176 [+], 519	254797081	inorganic diphosphatase
2	NRI_0709	673441..673878 [-], 438	254797082	hypothetical protein
3	NRI_0710	673958..674314 [-], 357	254797083	hypothetical protein
4	NRI_0711 (gltX)	674374..675603 [-], 1230	254797084	glutamyl-tRNA synthetase
5	NRI_0712	675702..676259 [-], 558	254797085	membrane protein
6	NRI_0713	676486..678411 [-], 1926	254797086	type IV secretion system component VirD4	VirD4
7	NRI_0714 (virB)	678443..679438 [-], 996	254797087	type IV secretion system ATPase VirB11	VirB11
8	NRI_0715	679445..680686 [-], 1242	254797088	type IV secretion system protein VirB10	VirB10
9	NRI_0716	680664..680822 [-], 159	254797089	type IV secretion system protein VirB10, Frame-Shift
10	NRI_0717 (virB9)	680829..681551 [-], 723	254797090	type IV secretion system protein VirB9	VirB9
11	NRI_0718	681538..682248 [-], 711	254797091	type IV secretion system protein VirB8	VirB8
12	NRI_0719	682490..683551 [-], 1062	254797092	GTP cyclohydrolase II
13	NRI_0720 (pdhB)	683781..684779 [+], 999	254797093	pyruvate dehydrogenase subunit beta
14	NRI_0721	685143..685406 [+], 264	254797094	hypothetical protein
15	NRI_0722	685575..685898 [+], 324	254797095	hypothetical protein

Region 3: 701053..254797112

#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	NRI_0734	696638..696973 [-], 336	254797106	ATP synthase subunits delta/epsilon
2	NRI_0735 (atpD)	696974..698398 [-], 1425	254797107	F0F1 ATP synthase subunit beta
3	NRI_0736	698537..701086 [-], 2550	254797108	hypothetical protein
4	NRI_0737	701053..703200 [-], 2148	254797109	type IV secretion system protein VirB4	VirB4
5	NRI_0738	703399..703761 [-], 363	254797110	type IV secretion system protein VirB2	VirB2
6	NRI_0739	703655..703771 [-], 117	254797111	hypothetical protein
7	NRI_0740	703972..704319 [-], 348	254797112	type IV secretion system protein VirB2	VirB2
8	NRI_0742	704105..704533 [+], 429	254797113	lipoprotein
9	NRI_0741 (lepA)	704505..706295 [-], 1791	254797114	GTP-binding protein LepA
10	NRI_0743 (lysK)	706477..707994 [-], 1518	254797115	lysyl-tRNA synthetase
11	NRI_0744	708427..708906 [+], 480	254797116	hypothetical protein
12	NRI_0745	709092..709970 [-], 879	254797117	molybdopterin biosynthesis protein MoeB
13	NRI_0746	710044..711045 [+], 1002	254797118	thioredoxin reductase
14	NRI_0747 (hisS)	711232..712473 [-], 1242	254797119	histidyl-tRNA synthetase
15	NRI_0748	712454..712741 [-], 288	254797120	BolA family protein
16	NRI_0749	712824..714071 [-], 1248	254797121	major facilitator family transporter
17	NRI_0750 (lepB)	714510..715139 [+], 630	254797122	signal peptidase I
18	NRI_0751	715266..716516 [-], 1251	254797123	hypothetical protein
19	NRI_0752	716564..716740 [+], 177	254797124	hypothetical protein
20	NRI_0753	716790..718130 [+], 1341	254797125	hypothetical protein
21	NRI_0754	718145..718681 [+], 537	254797126	hypothetical protein
22	NRI_0755	718839..719660 [+], 822	254797127	hypothetical protein
23	NRI_0756 (hemH)	719676..720653 [-], 978	254797128	ferrochelatase
24	NRI_0757	720784..721752 [-], 969	254797129	hypothetical protein
25	NRI_0758 (rpsT)	721823..722086 [-], 264	254797130	ribosomal protein S20
26	NRI_0759	722223..722345 [-], 123	254797131	hypothetical protein
27	NRI_0760 (pyrF)	722549..723235 [+], 687	254797132	orotidine 5'-phosphate decarboxylase
28	NRI_0761	723279..723977 [-], 699	254797133	membrane protein, TerC family
29	NRI_0762	724181..724303 [-], 123	254797134	hypothetical protein
30	NRI_0763	724490..725989 [+], 1500	254797135	propionyl-CoA carboxylase beta chain
31	NRI_0764	726091..726654 [+], 564	254797136	hypothetical protein
32	NRI_0765	726820..728142 [+], 1323	254797137	outer membrane efflux protein
33	NRI_0766 (ispG)	728237..729481 [-], 1245	254797138	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
34	NRI_0767	729534..730241 [-], 708	254797139	inositol monophosphatase family protein
35	NRI_0768 (pdhA)	730337..731305 [-], 969	254797140	pyruvate dehydrogenase E1 component, alpha subunit
36	NRI_0770	734352..734510 [-], 159	254797141	hypothetical protein
37	NRI_0771	734558..734674 [+], 117	254797142	hypothetical protein
38	NRI_0772	734664..735506 [+], 843	254797143	4-hydroxybenzoate octaprenyltransferase
39	NRI_0773	735503..735961 [+], 459	254797144	flavin reductase family protein
40	NRI_0774	736063..736830 [+], 768	254797145	phosphate import ATP-binding protein PstB
41	NRI_0776	737285..737416 [-], 132	254797146	hypothetical protein
42	NRI_0777 (smpB)	737485..737928 [-], 444	254797147	SsrA-binding protein
43	NRI_0778	738175..741015 [+], 2841	254797148	phosphoribosylformylglycinamidine synthase
44	NRI_0779	741054..741206 [-], 153	254797149	hypothetical protein
45	NRI_0780	741571..742842 [-], 1272	254797150	permease
46	NRI_0781	742981..744939 [-], 1959	254797151	propionyl-CoA carboxylase alpha chain
47	NRI_0782	744911..745810 [-], 900	254797152	ribose-phosphate pyrophosphokinase
48	NRI_0783	745819..745968 [-], 150	254797153	hypothetical protein
49	NRI_0784	745988..746530 [-], 543	254797154	hira-interacting protein 5
50	NRI_0785	746611..746997 [+], 387	254797155	DnaJ domain protein
51	NRI_0787	747208..747690 [+], 483	254797156	NADH dehydrogenase subunit I
52	NRI_0786	747652..747789 [-], 138	254797157	hypothetical protein
53	NRI_0788	747811..747954 [-], 144	254797158	hypothetical protein
54	NRI_0790	747917..748561 [+], 645	254797159	tetrahydrofolate dehydrogenase/cyclohydrolase
55	NRI_0792	748829..749227 [-], 399	254797160	hypothetical protein
56	NRI_0793	749304..750665 [+], 1362	254797161	hypothetical protein
57	NRI_0794	750771..751859 [-], 1089	254797162	Ser/Thr protein phosphatase
58	NRI_0797 (hemA)	752494..753714 [+], 1221	254797163	5-aminolevulinate synthase
59	NRI_0798 (rpsU)	753743..753937 [-], 195	254797164	ribosomal protein S21
60	NRI_0799	754013..754420 [-], 408	254797165	cytochrome c-type biogenesis protein CcmE
61	NRI_0800	754422..756050 [-], 1629	254797166	metallo-beta-lactamase family, beta-casp subfamily
62	NRI_0802 (miaB)	756450..757814 [+], 1365	254797167	tRNA-I(6)A37 thiotransferase enzyme MiaB
63	NRI_0801	757811..757990 [-], 180	254797168	hypothetical protein
64	NRI_0804	758495..758656 [+], 162	254797169	hypothetical protein
65	NRI_0805 (phrB)	758826..760235 [+], 1410	254797170	deoxyribodipyrimidine photolyase
66	NRI_0806	760267..760989 [-], 723	254797171	hypothetical protein
67	NRI_0807 (rpsI)	761023..761460 [-], 438	254797172	30S ribosomal protein S9
68	NRI_0808 (rplM)	761463..761921 [-], 459	254797173	50S ribosomal protein L13
69	NRI_0809	761985..762626 [-], 642	254797174	CvpA family protein
70	NRI_0810	762627..765116 [-], 2490	254797175	trap transporter, 4tm/12tm fusion protein
71	NRI_0811	765234..765851 [-], 618	254797176	superoxide dismutase, Fe
72	NRI_0812	766033..766623 [+], 591	254797177	glycoprotease family protein
73	NRI_0813	766644..767786 [+], 1143	254797178	branched-chain amino acid transporter
74	NRI_0814	767982..769181 [+], 1200	254797179	major facilitator family transporter
75	NRI_0815	769190..770221 [-], 1032	254797180	mechanosensitive ion channel family protein
76	NRI_0817	770576..771283 [+], 708	254797181	hypothetical protein
77	NRI_0818	771317..771472 [-], 156	254797182	hypothetical protein
78	NRI_0819 (argD)	771476..772465 [+], 990	254797183	acetylornithine transaminase protein
79	NRI_0820	772528..773187 [-], 660	254797184	peptidyl-prolyl cis-trans isomerase, cyclophilin-type
80	NRI_0821 (purC)	773327..774049 [-], 723	254797185	phosphoribosylaminoimidazole-succinocarboxamide synthase
81	NRI_0822 (ribE)	774363..774965 [+], 603	254797186	riboflavin synthase subunit alpha
82	NRI_0823 (lgt)	775070..775870 [+], 801	254797187	prolipoprotein diacylglyceryl transferase
83	NRI_0824 (coxW)	775913..776932 [-], 1020	254797188	cytochrome c oxidase assembly protein
84	NRI_0825	777362..777580 [+], 219	254797189	ribonuclease P protein component
85	NRI_0826	777583..777894 [+], 312	254797190	hypothetical protein
86	NRI_0827	777907..781179 [-], 3273	254797191	type IV secretion system protein, VirB6 family	VirB6
87	NRI_0828	781166..784648 [-], 3483	254797192	type IV secretion system protein, VirB6 family	VirB6
88	NRI_0829	784683..787202 [-], 2520	254797193	type IV secretion system protein, VirB6 family	VirB6
89	NRI_0830	787219..789780 [-], 2562	254797194	type IV secretion system protein VirB6	VirB6
90	NRI_0831	789777..792188 [-], 2412	254797195	type IV secretion system ATPase VirB4	VirB4
91	NRI_0832	792191..792487 [-], 297	254797196	type IV secretion system protein VirB3	VirB3
92	NRI_0833	792817..794628 [-], 1812	254797197	efflux ABC transporter, heavy metal transporter (HMT) family, permease/ATP-binding protein
93	NRI_0834	794731..795798 [-], 1068	254797198	phospholipase, patatin family
94	NRI_0835	795815..795991 [-], 177	254797199	hypothetical protein
95	NRI_0836	796168..797034 [+], 867	254797200	hypothetical protein
96	NRI_0837	797138..798001 [+], 864	254797201	alpha/beta hydrolase
97	NRI_0838 (nsp1)	798127..798909 [+], 783	254797202	Wsp-like surface protein
98	NRI_0839 (nsp2)	799233..800159 [+], 927	254797203	Wsp-like surface protein
99	NRI_0840	800159..800335 [+], 177	254797204	hypothetical protein
100	NRI_0841 (nsp3)	800528..801256 [+], 729	254797205	Wsp-like surface protein
101	NRI_0842	801317..801640 [+], 324	254797206	preprotein translocase subunit SecG
102	NRI_0843 (pyrG)	801615..803279 [+], 1665	254797207	CTP synthetase
103	NRI_0846	803629..805584 [+], 1956	254797208	hypothetical protein
104	NRI_0847	805592..806017 [-], 426	254797209	N utilization substance protein B
105	NRI_0848	806007..806627 [-], 621	254797210	hypothetical protein
106	NRI_0849 (infA)	806670..806951 [-], 282	254797211	translation initiation factor IF-1
107	NRI_0850	807003..807218 [-], 216	254797212	hypothetical protein
108	NRI_0851	807296..807553 [-], 258	254797213	hypothetical protein
109	NRI_0852	807330..807860 [+], 531	254797214	thiol-disulfide isomerase, thioredoxin family
110	NRI_0853	807882..809618 [+], 1737	254797215	glutathione-regulated potassium-efflux system protein
111	NRI_0854 (guaA)	809681..811240 [-], 1560	254797216	GMP synthase
112	NRI_0855 (mrp)	811371..812111 [-], 741	254797217	Mrp protein
113	NRI_0856 (ompA)	812524..813150 [+], 627	254797218	peptidoglycan-associated lipoprotein (PAL/OmpA)
114	NRI_0857	813161..814012 [+], 852	254797219	hypothetical protein
115	NRI_0858 (gpmI)	814082..815554 [+], 1473	254797220	phosphoglyceromutase
116	NRI_0859	815569..816342 [-], 774	254797221	hypothetical protein
117	NRI_0860 (metG)	816506..818071 [+], 1566	254797222	methionyl-tRNA synthetase
118	NRI_0861 (trx)	818107..818415 [-], 309	254797223	thioredoxin
119	NRI_0862 (rplS)	818425..818787 [-], 363	254797224	50S ribosomal protein L19
120	NRI_0863 (trmD)	818811..819467 [-], 657	254797225	tRNA (guanine-N1)-methyltransferase
121	NRI_0864 (rpmA)	819500..819748 [-], 249	254797226	50S ribosomal protein L27
122	NRI_0865 (rplU)	819800..820168 [-], 369	254797227	ribosomal protein L21
123	NRI_0866 (recR)	820211..820801 [-], 591	254797228	recombination protein RecR
124	NRI_0867	820872..821561 [+], 690	254797229	hypothetical protein
125	NRI_0868	821764..822609 [+], 846	254797230	disulfide oxidoreductase
126	NRI_0869	823002..823328 [+], 327	254797231	hypothetical protein
127	NRI_0870 (ssa1)	823570..825075 [+], 1506	254797232	50kDa strain-specific antigen
128	NRI_0871 (ssa2)	825199..826737 [+], 1539	254797233	50kDa strain-specific antigen
129	NRI_0872 (ssa3)	827285..828586 [+], 1302	254797234	50 kDa strain-specific antigen
130	NRI_0873 (ychF)	829039..830091 [+], 1053	254797235	GTP-dependent nucleic acid-binding protein EngD
131	NRI_0876	830405..830518 [-], 114	254797236	hypothetical protein
132	NRI_0877	830506..831852 [-], 1347	254797237	peptidase, M16 family
133	NRI_0878	831855..833168 [-], 1314	254797238	peptidase, M16 family
134	NRI_0879 (lspA)	833181..833684 [-], 504	254797239	signal peptidase II
135	NRI_0880	833739..835094 [-], 1356	254797240	carboxypeptidase
136	NRI_0881	835377..835736 [+], 360	254797241	hypothetical protein
137	NRI_0882	835726..836067 [+], 342	254797242	hypothetical protein
138	NRI_0883 (rnc)	836106..836774 [-], 669	254797243	ribonuclease III
139	NRI_0884	836765..836971 [-], 207	254797244	iojap-related protein
140	NRI_0885 (mraW)	837472..838362 [-], 891	254797245	S-adenosyl-methyltransferase MraW
141	NRI_0886	838492..839145 [-], 654	254797246	tRNA (guanine-N(7)-)-methyltransferase
142	NRI_0887	839239..839922 [-], 684	254797247	competence protein ComL
143	NRI_0888 (purD)	839945..841234 [+], 1290	254797248	phosphoribosylamine--glycine ligase
144	NRI_0889	841383..842147 [-], 765	254797249	hypothetical protein
145	NRI_0890	842171..842914 [-], 744	254797250	hypothetical protein
146	NRI_0891 (dapA)	843339..844265 [+], 927	254797251	dihydrodipicolinate synthase
147	NRI_0892	844412..844567 [-], 156	254797252	hypothetical protein
148	NRI_0893	845094..845522 [+], 429	254797253	cytochrome b561 family protein
149	NRI_0894	845823..846467 [+], 645	254797254	HAD-superfamily hydrolase, subfamily IA, variant 1
150	NRI_0895	846562..847305 [+], 744	254797255	uracil-DNA glycosylase, family 4
151	NRI_0896	847295..848062 [+], 768	254797256	VacJ lipoprotein
152	NRI_0897	848046..848657 [+], 612	254797257	hypothetical protein
153	NRI_0898	848712..848903 [-], 192	254797258	hypothetical protein
154	NRI_0899 (aprE)	849418..850917 [+], 1500	254797259	secretion protein, HlyD family
155	NRI_0900	851064..852194 [+], 1131	254797260	3-dehydroquinate synthase
156	NRI_0901	852199..852447 [+], 249	254797261	TPR repeat region superfamily
157	NRI_0902 (cdsA)	852525..853142 [-], 618	254797262	phosphatidate cytidylyltransferase
158	NRI_0903 (uppS)	853338..854030 [-], 693	254797263	UDP diphosphate synthase
159	NRI_0904 (frr)	854027..854584 [-], 558	254797264	ribosome recycling factor
160	NRI_0905 (pyrH)	854609..855310 [-], 702	254797265	uridylate kinase
161	NRI_0906 (tsf)	855317..856189 [-], 873	254797266	translation elongation factor Ts
162	NRI_0907 (rpsB)	856213..857109 [-], 897	254797267	30S ribosomal protein S2
163	NRI_0908	857085..857222 [-], 138	254797268	hypothetical protein
164	NRI_0909	857298..857990 [+], 693	254797269	ubiquinone/menaquinone biosynthesis methyltransferase UbiE
165	NRI_0910	858324..859763 [+], 1440	254797270	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase
166	NRI_0911	859961..860725 [+], 765	254797271	phosphomethylpyrimidine kinase
167	NRI_0912	860740..861240 [-], 501	254797272	crossover junction endodeoxyribonuclease RuvC
168	NRI_0913	861332..862279 [-], 948	254797273	malate dehydrogenase
169	NRI_0914	862443..862556 [-], 114	254797274	hypothetical protein
170	NRI_0915 (dut)	862627..863076 [+], 450	254797275	deoxyuridine 5triphosphate nucleotidohydrolase
171	NRI_0916	863171..863365 [+], 195	254797276	hypothetical protein
172	NRI_0917 (gyrA)	863371..865980 [+], 2610	254797277	DNA gyrase, A subunit
173	NRI_0918 (era)	866180..867079 [-], 900	254797278	GTP-binding protein Era
174	NRI_0919 (fabD)	867185..868120 [-], 936	254797279	malonyl CoA-acyl carrier protein transacylase
175	NRI_0920	868198..869937 [-], 1740	254797280	DNA primase
176	NRI_0921 (acpS)	869978..870343 [-], 366	254797281	holo-ACP synthase
177	NRI_0922	870508..871674 [+], 1167	254797282	hypothetical protein
178	NRI_0923 (dcd)	871867..872415 [-], 549	254797283	deoxycytidine triphosphate deaminase
179	NRI_0924	872505..872627 [+], 123	254797284	hypothetical protein
180	NRI_0925 (purK)	872886..873914 [+], 1029	254797285	phosphoribosylaminoimidazole carboxylase, ATPase subunit
181	NRI_0926	873996..874631 [-], 636	254797286	hypothetical protein
182	NRI_0927	874710..876107 [+], 1398	254797287	phage protein
183	NRI_0928 (hemE)	876519..877487 [+], 969	254797288	uroporphyrinogen decarboxylase
184	NRI_0929 (nadA)	877537..878493 [+], 957	254797289	quinolinate synthetase
185	NRI_0930 (coaD)	878510..878995 [-], 486	254797290	pantetheine-phosphate adenylyltransferase
186	NRI_0931	879000..879824 [-], 825	254797291	hypothetical protein
187	NRI_0932	879778..879915 [+], 138	254797292	hypothetical protein

Region 4: 777907..792487

#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	NRI_0821 (purC)	773327..774049 [-], 723	254797185	phosphoribosylaminoimidazole-succinocarboxamide synthase
2	NRI_0822 (ribE)	774363..774965 [+], 603	254797186	riboflavin synthase subunit alpha
3	NRI_0823 (lgt)	775070..775870 [+], 801	254797187	prolipoprotein diacylglyceryl transferase
4	NRI_0824 (coxW)	775913..776932 [-], 1020	254797188	cytochrome c oxidase assembly protein
5	NRI_0825	777362..777580 [+], 219	254797189	ribonuclease P protein component
6	NRI_0826	777583..777894 [+], 312	254797190	hypothetical protein
7	NRI_0827	777907..781179 [-], 3273	254797191	type IV secretion system protein, VirB6 family	VirB6
8	NRI_0828	781166..784648 [-], 3483	254797192	type IV secretion system protein, VirB6 family	VirB6
9	NRI_0829	784683..787202 [-], 2520	254797193	type IV secretion system protein, VirB6 family	VirB6
10	NRI_0830	787219..789780 [-], 2562	254797194	type IV secretion system protein VirB6	VirB6
11	NRI_0831	789777..792188 [-], 2412	254797195	type IV secretion system ATPase VirB4	VirB4
12	NRI_0832	792191..792487 [-], 297	254797196	type IV secretion system protein VirB3	VirB3
13	NRI_0833	792817..794628 [-], 1812	254797197	efflux ABC transporter, heavy metal transporter (HMT) family, permease/ATP-binding protein
14	NRI_0834	794731..795798 [-], 1068	254797198	phospholipase, patatin family
15	NRI_0835	795815..795991 [-], 177	254797199	hypothetical protein
16	NRI_0836	796168..797034 [+], 867	254797200	hypothetical protein

Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files

Proteins Genes

(1) Lin M; Zhang C; Gibson K; Rikihisa Y (2009). Analysis of complete genome sequence of Neorickettsia risticii: causative agent of Potomac horse fever. Nucleic Acids Res. 37(18):6076-91. [PudMed:19661282]

This literature contains experimental investigation