oriTDB

oriT
Relaxosome
T4CP
Plasmid&Host

The information of the oriT region

oriTDB accession number	100989
Name	oriT_pNDM229
Sequence Completeness	incomplete
oriT length	38 nt
oriT sequence	AGGGATTCATAAGGGAATTATTCCCTTATGTGGGGCTT
IR (inverted repeat)	[8-17] [21-30] nt (CATAAGGGAA..TTCCCTTATG)
Location of nic site	_
Conserved sequence flanking the nic site	_
Note	predicted by the oriTfinder
	L:8-17;R:21-30

Visualization of oriT structure

Reference
N/A

I. Information of Relaxase

ID	1059
Name	TraA_pNDM229
GenBank accession number	WP_017480453
Family	MOB_Q
Length	970 aa
UniProt ID	_
PDB ID	_
Pfam	AAA_30 [PF13604.5], Evalue: 3.50E-45, Aligned region: 345..541 MobA_MobL [PF03389.14], Evalue: 1.60E-26, Aligned region: 22..211 AAA_19 [PF13245.5], Evalue: 1.60E-10, Aligned region: 350..477 Viral_helicase1 [PF01443.17], Evalue: 1.50E-05, Aligned region: 591..710
Note	putative relaxase
Protein sequence [Download]	MAIYHLSVKTGRQYGSTGTRGANHYAYINRDGKYKRDDLENIKSGNLPSWATDAKHFWKS ADKNERINGRVYTELEISLPRELNKEQREELVEKFVEKTLGENFTYSYAIHSPLASDGQQ NPHVHLMFSERKLDGIERDEVKHFKRYNPVNPEKGGAGKDRYFSSKMFVVDTRLEWANHV NDFCENLGIDARIDHRSFKEQGIELSSQNFRADYVSSHKYHINENIKQVRHQNGEIIIER PSEAIKALTSNQSVFSVRELERFLMAHTDGEEQYLKAYESVITCPDMATLYGKDKVVFSS KELVGIEESISTFIYNANEESRIQKPFNLVEKLPLNAVRVAETRTFNSEQEKAFYTLTST DRITLLNGSAGTGKSYVLSAVSEAYKESDYQVYGIALQAITAKAIANDCDIPSSTIASFL SKYDSGNLEINNKTVLILDEAGMVGSRDMQRLLMLVEKHDAQIKLVGDSYQLSAVSAGHV FANIQENLDKKNIASLEDIQRQKHAKESDKMIQASKYLSKHEVGKAIDIYKSINMVNEYE SHDLALAKTVKSWSEDSSESKLMLAHSNSDVNELNRMARALLIKQGKLNPESVSVKNYQG DLDISIGEKIVFKQNNSQMKVSNGELAKVIGFEKDKFNNPKAMMVQMESDSRIVRVDLKE YDQFKHGYANTIHSSQGMTVDSAYIVASENMNANLTYVALTRHKQNIQINYSALTFATNE KETVKTPDGKVSYDHNYKPVEREVTAFENFKKVLGRSETKEFSTDFTLVESKDNLMKSYL NDHRLHLENKRELFGINSKLYSLTSENKTFTKEEIVSEVRASLKSKALLGDEIVKFNGNM NIAKGELVKLTNDLEIKTGLFKKVTFEKGTELKVIDAYKVKDKPVMKARIKNEEYEIPFN KLNLEYSDKYFNEFKDQSKARFDSRHKTEVYTEFREQLLKQKANAPKDNLNAPNQRIKNP NTPNRNTPKY

Reference
N/A

II. Auxiliary DNA-binding protein(s) of the relaxosome
N/A

N/A

Information of plasmid

ID	1447
Plasmid name	pNDM229
GenBank accession number	NZ_KT072713.1
Genome size	44560 bp
Coordinate of oriT [Strand]	1..38 [+]
Drug resistance	_
Heavy-metal resistance	_
Virulence factor	_
Xenobiotic degradation	_
Host bacterium [NCBI Taxonomy ID]	Acinetobacter bereziniae HPC229 [106648]

Reference

[1] Brovedan M et al (2016) Draft Genome Sequence of Acinetobacter bereziniae HPC229, a Carbapenem-Resistant Clinical Strain from Argentina Harboring blaNDM-1. Genome Announc. 4(2). [PMID:26966220]

[2] Brovedan M et al (2015) Complete Sequence of a bla(NDM-1)-Harboring Plasmid in an Acinetobacter bereziniae Clinical Strain Isolated in Argentina. Antimicrob Agents Chemother. 59(10):6667-9. [PMID:26248354]