SecReT4
T4SS ID147
StrainBartonella tribocorum CIP 105476
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_010161
Location2441450..2462941
NameTrw
Functionadherence to erythrocytes
ClassificationType IVA; Type P
experimental Experimental investigation has been performed on this T4SS.

T4SS components
ComponentTrwBTrwDTrwETrwFTrwGTrwHTrwITrwJTrwK
Number011114551
ComponentTrwLTrwMTrwN
Number711

The information of T4SS components from NC_010161
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1Btr_2505 (ubiH2)2437302..2438579 [+], 12781638692112-octaprenyl-6-methoxyphenyl hydroxylase 
2Btr_2507 (korB)2440422..2440709 [-], 288163869212trans-acting regulatory protein 
3Btr_25082440839..2441450 [+], 612163869213hypothetical protein 
4Btr_2509 (trwN)2441450..2442091 [+], 642163869214TrwN protein  TrwN
5Btr_2510 (korA)2442212..2442511 [+], 300163869215KorA protein 
6Btr_2511 (trwL1)2442474..2442791 [+], 318163869216TrwL1 protein  TrwL
7Btr_2512 (trwL2)2442932..2443252 [+], 321163869217TrwL2 protein  TrwL
8Btr_2513 (trwL3)2443390..2443707 [+], 318163869218TrwL3 protein  TrwL
9Btr_2514 (trwL4)2443848..2444168 [+], 321163869219TrwL4 protein  TrwL
10Btr_2515 (trwL5)2444290..2444604 [+], 315163869220TrwL5 protein  TrwL
11Btr_2516 (trwL6)2444742..2445062 [+], 321163869221TrwL6 protein  TrwL
12Btr_2516a (trwL7)2445194..2445505 [+], 312163869222TrwL7 protein  TrwL
13Btr_2517 (trwM)2445518..2445826 [+], 309163869223TrwM protein  TrwM
14Btr_2518 (trwK)2445829..2448300 [+], 2472163869224TrwK protein  TrwK
15Btr_2519 (trwJ1)2448297..2449046 [+], 750163869225TrwJ1 protein  TrwJ
16Btr_2521 (trwI1)2449233..2450078 [+], 846163869226TrwI1 protein  TrwI
17Btr_2521a (trwH1)2450239..2450460 [+], 222163869227TrwH1 protein  TrwH
18Btr_2522 (trwJ2)2450457..2451389 [+], 933163869228TrwJ2 protein  TrwJ
19Btr_2523 (trwI2)2451573..2452418 [+], 846163869229TrwI2 protein  TrwI
20Btr_2523a (trwH2)2452658..2452801 [+], 144163869230TrwH2 protein  TrwH
21Btr_2524 (trwJ3)2452798..2453529 [+], 732163869231TrwJ3 protein  TrwJ
22Btr_2525 (trwI3)2453714..2454559 [+], 846163869232TrwI3 protein  TrwI
23Btr_2526 (trwJ4)2454760..2455536 [+], 777163869233TrwJ4 protein  TrwJ
24Btr_2527 (trwI4)2455757..2456602 [+], 846163869234TrwI4 protein  TrwI
25Btr_2527a (trwH4)2456842..2456985 [+], 144163869235TrwH4 protein  TrwH
26Btr_2528 (trwJ5)2456982..2457833 [+], 852163869236TrwJ5 protein  TrwJ
27Btr_2529 (trwI5)2458017..2458862 [+], 846163869237TrwI5 protein  TrwI
28Btr_2529a (trwH5)2459102..2459245 [+], 144163869238TrwH5 protein  TrwH
29Btr_2530 (trwG)2459242..2459943 [+], 702163869239TrwG protein  TrwG
30Btr_2531 (trwF)2459957..2460763 [+], 807163869240TrwF protein  TrwF
31Btr_2532 (trwE)2460763..2461905 [+], 1143163869241TrwE protein  TrwE
32Btr_2533 (trwD)2461880..2462941 [+], 1062163869242TrwD protein  TrwD
33Btr_25382465264..2465464 [+], 201163869243hypothetical protein 
34Btr_25392466200..2466520 [-], 321163869244hypothetical protein 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes
(1) Franz B; Kempf VA (2011). Adhesion and host cell modulation: critical pathogenicity determinants of Bartonella henselae. Parasit Vectors. 4:54. [PudMed:21489243]
(2) Vayssier-Taussat M; Le Rhun D; Deng HK; Biville F; Cescau S; Danchin A; Marignac G; Lenaour E; Boulouis HJ; Mavris M; Arnaud L; Yang H; Wang J; Quebatte M; Engel P; Saenz H; Dehio C (2010). The Trw type IV secretion system of Bartonella mediates host-specific adhesion to erythrocytes. PLoS Pathog. 6(6):e1000946. [PudMed:20548954] experimental
(3) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] experimental
(4) Seubert A; Hiestand R; de la Cruz F; Dehio C (2003). A bacterial conjugation machinery recruited for pathogenesis. Mol Microbiol. 49(5):1253-66. [PudMed:12940985] experimental
 
experimental This literature contains experimental investigation