ICEberg
ICEberg contains data from 695 references related to integrative and conjugative elements (ICEs), integrative and mobilizable elements (IMEs), cis-mobilizable element (CIMEs). Last Update: May 02, 2018

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References
(1) Kambarev S et al (2017). Draft Genome Sequences of Two Highly Erythromycin-Resistant Streptococcus gallolyticus subsp. gallolyticus Isolates Containing a Novel Tn916-Like Element, Tn6331. Genome Announc. 5(16). [PubMed:28428309]
(2) Han X et al (2015). Functional analysis of a bacitracin resistance determinant located on ICECp1, a novel Tn916-like element from a conjugative plasmid in Clostridium perfringens. Antimicrob Agents Chemother. 59(11):6855-65. [PubMed:26282424]
(3) Chancey ST et al (2015). Composite mobile genetic elements disseminating macrolide resistance in Streptococcus pneumoniae. Front Microbiol. 6:26. [PubMed:25709602]
(4) Wasels F et al (2014). Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB. Microb Drug Resist. 20(6):555-60. [PubMed:25055190]
(5) Wasels F et al (2013). Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. J Med Microbiol. 62(Pt 9):1461-7. [PubMed:23741023]
(6) Bertsch D et al (2013). Tn6198, a novel transposon containing the trimethoprim resistance gene dfrG embedded into a Tn916 element in Listeria monocytogenes. J Antimicrob Chemother. 68(5):986-91. [PubMed:23344576]
(7) He M et al (2013). Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat Genet. 45(1):109-13. [PubMed:23222960]
(8) Palmieri C et al (2011). Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. Front Microbiol. 0.246527778. [PubMed:22275909]
(9) Ciric L, Mullany P, Roberts AP (2011). Antibiotic and antiseptic resistance genes are linked on a novel mobile genetic element: Tn6087. J Antimicrob Chemother. 66(10):2235-9. [PubMed:21816764]
(10) Lin IH et al (2011). Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence. PLoS One. 6(5):e20519. [PubMed:21633709]
(11) Croucher NJ et al (2011). Rapid pneumococcal evolution in response to clinical interventions. Science. 331(6016):430-4. [PubMed:21273480]
(12) Cookson AL et al (2011). Transposition of Tn916 in the four replicons of the Butyrivibrio proteoclasticus B316(T) genome. FEMS Microbiol Lett. 316(2):144-51. [PubMed:21204937]
(13) Top J et al (2011). The recombinase IntA is required for excision of esp-containing ICEEfm1 in Enterococcus faecium. J Bacteriol. 193(4):1003-6. [PubMed:21148730]
(14) Li Y et al (2011). Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. J Appl Microbiol. 110(1):254-65. [PubMed:20961364]
(15) Haenni M et al (2010). Diversity and mobility of integrative and conjugative elements in bovine isolates of Streptococcus agalactiae, S. dysgalactiae subsp. dysgalactiae, and S. uberis. Appl Environ Microbiol. 76(24):7957-65. [PubMed:20952646]
(16) Foucault ML et al (2010). Inducible expression eliminates the fitness cost of vancomycin resistance in enterococci. Proc Natl Acad Sci U S A. 107(39):16964-9. [PubMed:20833818]
(17) Jasni AS et al (2010). Demonstration of conjugative transposon (Tn5397)-mediated horizontal gene transfer between Clostridium difficile and Enterococcus faecalis. Antimicrob Agents Chemother. 54(11):4924-6. [PubMed:20713671]
(18) Rice LB et al (2010). Multiple copies of functional, Tet(M)-encoding Tn916-like elements in a clinical Enterococcus faecium isolate. Plasmid. 64(3):150-5. [PubMed:20600284]
(19) Schijffelen MJ et al (2010). Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis. BMC Genomics. 0.719444444. [PubMed:20546576]
(20) Santoro F et al (2010). Nucleotide sequence and functional analysis of the tet (M)-carrying conjugative transposon Tn5251 of Streptococcus pneumoniae. FEMS Microbiol Lett. 308(2):150-8. [PubMed:20487027]
(21) Stegmann R, Perreten V (2010). Antibiotic resistance profile of Staphylococcus rostri, a new species isolated from healthy pigs. Vet Microbiol. 145(1-2). [PubMed:20399039]
(22) van Schaik W et al (2010). Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island. BMC Genomics. 0.624305556. [PubMed:20398277]
(23) He M et al (2010). Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci U S A. 107(16):7527-32. [PubMed:20368420]
(24) Hannan S et al (2010). Transfer of antibiotic resistance by transformation with eDNA within oral biofilms. FEMS Immunol Med Microbiol. 59(3):345-9. [PubMed:20337719]
(25) Tsvetkova K et al (2010). Analysis of the mobilization functions of the vancomycin resistance transposon Tn1549, a member of a new family of conjugative elements. J Bacteriol. 192(3):702-13. [PubMed:19966009]
(26) Boguslawska J et al (2009). Intra- and interspecies conjugal transfer of Tn916-like elements from Lactococcus lactis in vitro and in vivo. Appl Environ Microbiol. 75(19):6352-60. [PubMed:19666731]
(27) de Vries LE et al (2009). Diversity of the tetracycline resistance gene tet(M) and identification of Tn916- and Tn5801-like (Tn6014) transposons in Staphylococcus aureus from humans and animals. J Antimicrob Chemother. 64(3):490-500. [PubMed:19531603]
(28) Devirgiliis C et al (2009). Characterization of the Tn916 conjugative transposon in a food-borne strain of Lactobacillus paracasei. Appl Environ Microbiol. 75(12):3866-71. [PubMed:19395574]
(29) Ding F et al (2009). Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14. BMC Genomics. 0.526388889. [PubMed:19361343]
(30) Meng F et al (2009). Structural characterization of Tn916-like element in Streptococcus parauberis serotype II strains isolated from diseased Japanese flounder. Lett Appl Microbiol. 48(6):770-6. [PubMed:19344360]
(31) Holden MT et al (2009). Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens. PLoS Pathog. 5(3):e1000346. [PubMed:19325880]
(32) Serfiotis-Mitsa D et al (2008). The Orf18 gene product from conjugative transposon Tn916 is an ArdA antirestriction protein that inhibits type I DNA restriction-modification systems. J Mol Biol. 383(5):970-81. [PubMed:18838147]
(33) Soge OO et al (2008). A novel transposon, Tn6009, composed of a Tn916 element linked with a Staphylococcus aureus mer operon. J Antimicrob Chemother. 62(4):674-80. [PubMed:18583328]
(34) Shen X et al (2008). Macrolide-resistance mechanisms in Streptococcus pneumoniae isolates from Chinese children in association with genes of tetM and integrase of conjugative transposons 1545. Microb Drug Resist. 14(2):155-61. [PubMed:18479199]
(35) Ye C et al (2008). Spread of Streptococcus suis sequence type 7, China. Emerg Infect Dis. 14(5):787-91. [PubMed:18439362]
(36) Florez AB et al (2008). Identification of tet(M) in two Lactococcus lactis strains isolated from a Spanish traditional starter-free cheese made of raw milk and conjugative transfer of tetracycline resistance to lactococci and enterococci. Int J Food Microbiol. 121(2):189-94. [PubMed:18068255]
(37) Warburton PJ et al (2007). Demonstration of in vivo transfer of doxycycline resistance mediated by a novel transposon. J Antimicrob Chemother. 60(5):973-80. [PubMed:17855723]
(38) Rossi-Fedele G et al (2007). A preliminary study investigating the survival of tetracycline resistant Enterococcus faecalis after root canal irrigation with high concentrations of tetracycline. Int Endod J. 40(10):772-7. [PubMed:17697106]
(39) Cochetti I et al (2007). New Tn916-related elements causing erm(B)-mediated erythromycin resistance in tetracycline-susceptible pneumococci. J Antimicrob Chemother. 60(1):127-31. [PubMed:17483548]
(40) Chen C et al (2007). A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. PLoS One. 2(3):e315. [PubMed:17375201]
(41) Rice LB et al (2007). Interaction of related Tn916-like transposons: analysis of excision events promoted by Tn916 and Tn5386 integrases. J Bacteriol. 189(10):3909-17. [PubMed:17322310]
(42) Brenciani A et al (2007). Genetic elements carrying erm(B) in Streptococcus pyogenes and association with tet(M) tetracycline resistance gene. Antimicrob Agents Chemother. 51(4):1209-16. [PubMed:17261630]
(43) Rossi-Fedele G et al (2006). Incidence and behaviour of Tn916-like elements within tetracycline-resistant bacteria isolated from root canals. Oral Microbiol Immunol. 21(4):218-22. [PubMed:16842505]
(44) Sebaihia M et al (2006). The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 38(7):779-86. [PubMed:16804543]
(45) Wang H et al (2006). The conjugative transposon Tn5397 has a strong preference for integration into its Clostridium difficile target site. J Bacteriol. 188(13):4871-8. [PubMed:16788196]
(46) Agerso Y et al (2006). Identification of Tn5397-like and Tn916-like transposons and diversity of the tetracycline resistance gene tet(M) in enterococci from humans, pigs and poultry. J Antimicrob Chemother. 57(5):832-9. [PubMed:16565159]
(47) Rocco JM et al (2006). The integrase of the conjugative transposon Tn916 directs strand- and sequence-specific cleavage of the origin of conjugal transfer, oriT, by the endonuclease Orf20. J Bacteriol. 188(6):2207-13. [PubMed:16513750]
(48) Abbani M et al (2005). The structure of the excisionase (Xis) protein from conjugative transposon Tn916 provides insights into the regulation of heterobivalent tyrosine recombinases. J Mol Biol. 347(1):11-25. [PubMed:15733914]
(49) Hussain HA et al (2005). Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites. J Med Microbiol. 54(Pt 2):137-41. [PubMed:15673506]
(50) Hirt H et al (2005). Characterization of the pheromone response of the Enterococcus faecalis conjugative plasmid pCF10: complete sequence and comparative analysis of the transcriptional and phenotypic responses of pCF10-containing cells to pheromone induction. J Bacteriol. 187(3):1044-54. [PubMed:15659682]
(51) Lancaster H et al (2004). Characterization of Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S). J Bacteriol. 186(13):4395-8. [PubMed:15205444]
(52) Gorfe AA et al (2004). The role of flexibility and hydration on the sequence-specific DNA recognition by the Tn916 integrase protein: a molecular dynamics analysis. J Mol Recognit. 17(2):120-31. [PubMed:15027032]
(53) Huys G et al (2004). Prevalence and molecular characterization of tetracycline resistance in Enterococcus isolates from food. Appl Environ Microbiol. 70(3):1555-62. [PubMed:15006778]
(54) Bahl MI et al (2004). Effect of tetracycline on transfer and establishment of the tetracycline-inducible conjugative transposon Tn916 in the guts of gnotobiotic rats. Appl Environ Microbiol. 70(2):758-64. [PubMed:14766552]
(55) Leavis H et al (2004). A novel putative enterococcal pathogenicity island linked to the esp virulence gene of Enterococcus faecium and associated with epidemicity. J Bacteriol. 186(3):672-82. [PubMed:14729692]
(56) Roberts AP et al (2003). Development of an integrative vector for the expression of antisense RNA in Clostridium difficile. J Microbiol Methods. 55(3):617-24. [PubMed:14607405]
(57) Taraskina AE et al (2002). Drift of tetM determinant in urogenital microbiocenosis containing mycoplasmas during treatment with a tetracycline antibiotic. Bull Exp Biol Med. 134(1):60-3. [PubMed:12459871]
(58) Burrus V et al (2002). The ICESt1 element of Streptococcus thermophilus belongs to a large family of integrative and conjugative elements that exchange modules and change their specificity of integration. Plasmid. 48(2):77-97. [PubMed:12383726]
(59) Tettelin H et al (2002). Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A. 99(19):12391-6. [PubMed:12200547]
(60) Connolly KM et al (2002). Xis protein binding to the left arm stimulates excision of conjugative transposon Tn916. J Bacteriol. 184(8):2088-99. [PubMed:11914339]
(61) Hinerfeld D et al (2001). Xis protein of the conjugative transposon Tn916 plays dual opposing roles in transposon excision. Mol Microbiol. 41(6):1459-67. [PubMed:11580848]
(62) Roberts AP et al (2001). Comparison of Tn5397 from Clostridium difficile, Tn916 from Enterococcus faecalis and the CW459tet(M) element from Clostridium perfringens shows that they have similar conjugation regions but different insertion and excision modules. Microbiology. 147(Pt 5):1243-51. [PubMed:11320127]
(63) Hinerfeld D et al (2001). Specific binding of integrase to the origin of transfer (oriT) of the conjugative transposon Tn916. J Bacteriol. 183(9):2947-51. [PubMed:11292817]
(64) Seral C et al (2000). [Presence of conjugative transposon Tn1545 in strains of Streptococcus pneumoniae with mef(A), erm(B), tet(M), catpC194 and aph3'-III genes]. Enferm Infecc Microbiol Clin. 18(10):506-11. [PubMed:11198001]
(65) Wang H et al (2000). The large resolvase TndX is required and sufficient for integration and excision of derivatives of the novel conjugative transposon Tn5397. J Bacteriol. 182(23):6577-83. [PubMed:11073898]
(66) Wang H et al (2000). DNA sequence of the insertional hot spot of Tn916 in the Clostridium difficile genome and discovery of a Tn916-like element in an environmental isolate integrated in the same hot spot. FEMS Microbiol Lett. 192(1):15-20. [PubMed:11040422]
(67) Wang H et al (2000). Characterization of the ends and target sites of the novel conjugative transposon Tn5397 from Clostridium difficile: excision and circularization is mediated by the large resolvase, TndX. J Bacteriol. 182(13):3775-83. [PubMed:10850994]
(68) Garnier F et al (2000). Characterization of transposon Tn1549, conferring VanB-type resistance in Enterococcus spp. Microbiology. 146 ( Pt 6):1481-9. [PubMed:10846226]
(69) Pethel B et al (2000). Coupling sequences flanking Tn916 do not determine the affinity of binding of integrase to the transposon ends and adjacent bacterial DNA. Plasmid. 43(2):123-9. [PubMed:10686130]
(70) Smidt H et al (1999). Random transposition by Tn916 in Desulfitobacterium dehalogenans allows for isolation and characterization of halorespiration-deficient mutants. J Bacteriol. 181(22):6882-8. [PubMed:10559152]
(71) Jia Y et al (1999). Interactions of the integrase protein of the conjugative transposon Tn916 with its specific DNA binding sites. J Bacteriol. 181(19):6114-23. [PubMed:10498726]
(72) Roberts AP et al (1999). Transfer of a conjugative transposon, Tn5397 in a model oral biofilm. FEMS Microbiol Lett. 177(1):63-6. [PubMed:10436923]
(73) Waters VL (1999). Conjugative transfer in the dissemination of beta-lactam and aminoglycoside resistance. Front Biosci. 4:D433-56. [PubMed:10228095]
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(78) McDougal LK et al (1998). Detection of Tn917-like sequences within a Tn916-like conjugative transposon (Tn3872) in erythromycin-resistant isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother. 42(9):2312-8. [PubMed:9736555]
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(80) Celli J et al (1998). Circularization of Tn916 is required for expression of the transposon-encoded transfer functions: characterization of long tetracycline-inducible transcripts reading through the attachment site. Mol Microbiol. 28(1):103-17. [PubMed:9593300]
(81) Nelson KE et al (1997). Tn916 transposition in Haemophilus influenzae Rd: preferential insertion into noncoding DNA. Microb Comp Genomics. 2(4):313-21. [PubMed:9689229]
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