ICEberg
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ICE family: ICEBs1
ICEBs1 is a well studied ICE. We selected it as a reference and defined ICEBs1 family. We classified any ICE that encodes an integrase gene closely related to int(ICEBs1), defined as over 60% protein homology and that has significant sequence alignment and syntenic 'core' structure into the ICEclc family.

#IDICE nameStrainReplicon
159 experimental ICEBs1Bacillus subtilis subsp. subtilis str. 168NC_000964
2217 in_silico ICEBat1942-1Bacillus atrophaeus 1942NC_014639
3767 in_silico ICEBp7061Bacillus pumilus ATCC7061
4768 in_silico ICEBpSAFR-032Bacillus pumilus SAFR-032
experimental Data derived from experimental literature
in_silico Putative ICEs predicted by bioinformatic methods
(1) Tirumalai MR et al. (2013). An ICEBs1-like element may be associated with the extreme radiation and desiccation resistance of Bacillus pumilus SAFR-032 spores. Extremophiles. 17(5):767-74. [PudMed:23812891] in_silico
(2) Lee CA et al. (2012). The Bacillus subtilis conjugative transposon ICEBs1 mobilizes plasmids lacking dedicated mobilization functions. J Bacteriol. 194(12):3165-72. [PudMed:22505685] experimental
(3) Babic A et al. (2011). Efficient gene transfer in bacterial cell chains. MBio. 2(2). [PudMed:21406598] experimental
(4) Smits WK et al. (2010). The transcriptional regulator Rok binds A+T-rich DNA and is involved in repression of a mobile genetic element in Bacillus subtilis. PLoS Genet. 6(11):e1001207. [PudMed:21085634] experimental
(5) Bose B et al. (2011). Regulation of horizontal gene transfer in Bacillus subtilis by activation of a conserved site-specific protease. J Bacteriol. 193(1):22-9. [PudMed:21036995] experimental
(6) Lee CA et al. (2010). Autonomous plasmid-like replication of a conjugative transposon. Mol Microbiol. 75(2):268-79. [PudMed:19943900] experimental
(7) Berkmen MB et al. (2010). Polar positioning of a conjugation protein from the integrative and conjugative element ICEBs1 of Bacillus subtilis. J Bacteriol. 192(1):38-45. [PudMed:19734305] experimental
(8) Bose B et al. (2008). A conserved anti-repressor controls horizontal gene transfer by proteolysis. Mol Microbiol. 70(3):570-82. [PudMed:18761623] experimental
(9) Lee CA et al. (2007). Identification and characterization of int (integrase), xis (excisionase) and chromosomal attachment sites of the integrative and conjugative element ICEBs1 of Bacillus subtilis. Mol Microbiol. 66(6):1356-69. [PudMed:18005101] experimental
(10) Lee CA et al. (2007). Identification of the origin of transfer (oriT) and DNA relaxase required for conjugation of the integrative and conjugative element ICEBs1 of Bacillus subtilis. J Bacteriol. 189(20):7254-61. [PudMed:17693500] experimental
(11) Goranov AI et al. (2006). Characterization of the global transcriptional responses to different types of DNA damage and disruption of replication in Bacillus subtilis. J Bacteriol. 188(15):5595-605. [PudMed:16855250] experimental
(12) Auchtung JM et al. (2005). Regulation of a Bacillus subtilis mobile genetic element by intercellular signaling and the global DNA damage response. Proc Natl Acad Sci U S A. 102(35):12554-9. [PudMed:16105942] experimental
 
experimental experimental literature
in_silico in silico analysis literature