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Group member    
   Faculty
Hong-Yu OU (欧竑宇)
Professor, Principle Investigator
Microbial Bioinformatics
ORCID: 0000-0001-9439-1660
Email: hyou@sjtu.edu.cn
ORCID: 0000-0001-9439-1660
Google Scholar: http://scholar.google.com/citations?user=R1SOS0QAAAAJ

欧竑宇,现任上海交通大学生命科学技术学院/微生物代谢国家重点实验室微生物学教授,微生物信息学研究组PI,博士生导师。1997年于南京农业大学获食品工程学士学位;2001年于天津科技大学获发酵工程硕士学位,师从贾士儒教授;2004年于天津大学获生物信息学博士学位,师从张春霆教授;随后在英国莱斯特大学医学院接受病原菌基因组学的两年博士后训练,合作导师 Dr. Kumar RAJAKUMAR 和 Prof. Mike BARER。2006年到上海交通大学任副教授,2012年起任教授。长期从事革兰阴性杆菌耐药移动元件的研究,开发了一系列专业数据库和生物信息学软件;并以肺炎克雷伯菌为实验体系,开展了四型分泌系统和毒素-抗毒素系统与细菌耐药性的相关研究。至今以通讯或第一作者在Nucleic Acids Research (11篇)、Briefings in Bioinformatics、Molecular Microbiology、Environmental Microbiology、Journal of Antimicrobial Chemotherapy和Antimicrobial Agents and Chemotherapy等专业知名刊物发表SCI论文三十余篇。先后主持5项国家自然科学基金项目和1项科技部863专题课题;2007年入选上海市青年科技启明星计划,2008年获明治乳业生命科学奖,2010年入选教育部新世纪优秀人才,2015年入选美国康奈尔大学唐氏中国学者。 

Contact:
Room 213, Science Building, Xuhui campus
1954 Huashan Road, Shanghai 200030, China
Email: hyou@sjtu.edu.cn; Tel: +86 21 62933765*2132
Education Experience:
2001.03-2004.02, Ph.D., Bioinformatics, Tianjin University, advised by Prof. Chun-Ting Zhang
1998.09-2001.03, M.S., Fermentation Engineering, Tianjin University of Science & Technology, advised by Prof. Shiru Jia
1993.09-1997.07, B.S., Food Engineering, Nanjing Agricultural University
Work Experience:
2012.01-present, Professor, Principle Investigator, Shanghai Jiao Tong University
2015.10-2016.9, Visiting Professor (Tang Cornell-China Scholar), Cornell University, work with Prof. Martin Wiedmann
2006.06-2011.12, Associate Professor, Shanghai Jiao Tong University
2004.06-2006.05, Research Associate, Medical School, University of Leicester, UK, worked with Dr. Kumar RAJAKUMAR and Prof. Mike BARER
 
 Selected Publications (2007-present):
 Linkage to the publications of Prof. Ou's group.
 
Selected Publications (2003-2006):

(11) Ou HY, Chen LL, Lonnen J, Chaudhuri RR, Thani AB, Smith R, Garton NJ, Hinton J, Pallen M, Barer MR, Rajakumar K* (2006) A novel strategy for identification of genomic islands by comparative analysis of the contents and contexts of tRNA sites in closely related bacteria. Nucleic Acids Res., 34, e3. [Abstract][PDF][Supplementary materials]
(10) Ou HY, Smith R, Lucchini S, Hinton J, Chaudhuri RR, Pallen M, Barer MR, Rajakumar K* (2005) ArrayOme: a program for estimating the sizes of the microarray-visualised genomes. Nucleic Acids Res. , 33, e3. [Abstract][PDF]
(9)Zheng WX, Chen LL, Ou HY, Gao F, Zhang CT* (2005) Coronavirus phylogeny based on a geometric approach. Mol. Phyl. Evol. , 36, 224-232. [Abstract]
(8)Ou HY, Guo FB, Zhang CT* (2004). GS-Finder: a program to find bacterial gene start sites with a self-training method. Int. J. Biochem. Cell Biol. 36, 535-544.[Abstract]
(7) Zhang R, Ou HY, Zhang CT* (2004) DEG, a Database of Essential Genes. Nucleic Acids Res.32, D271-D272. [Abstract][PDF]
(6) Ou HY, Guo FB, Zhang CT* (2003) Analysis of nucleotide distribution in the genome of Streptomyces coelicolor A3(2) using the Z curve method. FEBS Letters 540, 188-194.[Abstract]
(5) Guo FB, Ou HY, Zhang CT* (2003) ZCURVE: a new system for recognizing protein-coding genes in bacterial and archaeal genomes. Nucleic Acids Res. 31, 1780-1789.[Abstract][PDF]
(4) Zhang CT*, Zhang R, Ou HY (2003) The Z curve database: a graphic representation of genome sequences. Bioinformatics 19, 593-599. [Abstract]
(3) Wang Y*, Ou HY, Guo F (2003) Recognition of translation initiation sites of eukaryotic genes based on EM algorithm. J. Comput. Biol. 10, 699-708. [Abstract]
(2) Chen LL¶ , Ou HY¶, Zhang R, Zhang CT* (2003) ZCURVE_CoV: a new system to recognize protein coding genes in coronavirus genomes, and its applications in analyzing SARS-CoV genomes. Biochem. Biophys. Res. Commun. 307, 382-388. (¶ These authors contributed equally to this work.) [Abstract]
(1) Gao F, Ou HY, Chen LL, Zheng WX, Zhang CT* (2003) Prediction of proteinase cleavage sites in polyproteins of coronaviruses and its applications in analyzing SARS-CoV genomes. FEBS Letters, 553, 451-456. [Abstract]

 


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