Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 168952..169468 Replicon chromosome
Accession NZ_CP027706
Organism Pseudomonas sp. CMR12a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4K39_RS00770 Protein ID WP_124345436.1
Coordinates 169187..169468 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K39_RS00765 Protein ID WP_085598199.1
Coordinates 168952..169197 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K39_RS00745 163953..166169 - 2217 WP_124345433.1 outer membrane assembly lipoprotein YfiO -
C4K39_RS00750 166434..168017 + 1584 WP_124345434.1 glycosyltransferase family 39 protein -
C4K39_RS00755 168166..168627 + 462 WP_068576252.1 YbaK/EbsC family protein -
C4K39_RS00760 168642..168890 + 249 WP_124345435.1 DUF2789 domain-containing protein -
C4K39_RS00765 168952..169197 + 246 WP_085598199.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C4K39_RS00770 169187..169468 + 282 WP_124345436.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K39_RS00775 169600..170028 + 429 WP_068576245.1 winged helix DNA-binding protein -
C4K39_RS00780 170025..172112 + 2088 WP_124345437.1 FUSC family protein -
C4K39_RS00785 172109..172318 + 210 WP_022643266.1 DUF1656 domain-containing protein -
C4K39_RS00790 172315..173205 + 891 WP_068576241.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10807.85 Da        Isoelectric Point: 10.6758

>T99887 WP_124345436.1 NZ_CP027706:169187-169468 [Pseudomonas sp. CMR12a]
MTYKLEFLPSALKEWNKLGHTLREQFKKKLAQRLQMPQVPADALYGLPDCYKIKLKASGYRLVYKVIEQRVVVAVVAVGK
RERGAVYEQARKR

Download         Length: 282 bp

>T99887 NZ_CP027706:169187-169468 [Pseudomonas sp. CMR12a]
ATGACTTATAAACTCGAGTTCCTGCCTTCGGCGCTCAAGGAGTGGAACAAGCTGGGCCATACGCTTCGCGAGCAATTCAA
GAAGAAGCTCGCGCAACGGCTGCAAATGCCCCAAGTCCCAGCAGATGCCCTGTACGGTTTACCCGACTGCTACAAGATTA
AGCTCAAGGCCTCGGGTTATCGGCTGGTCTATAAGGTTATCGAGCAGCGCGTTGTGGTGGCTGTTGTCGCGGTCGGTAAG
CGCGAGCGCGGGGCTGTGTACGAGCAAGCCAGGAAGCGTTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8759.08 Da        Isoelectric Point: 4.3455

>AT99887 WP_085598199.1 NZ_CP027706:168952-169197 [Pseudomonas sp. CMR12a]
MQSILADKAVSVSELKKNPSAVLNGAQGGPVAVLNHNRVMGYMIPAEVFEALMERLDDLELAEIVRARSQETPVPVSLDD
L

Download         Length: 246 bp

>AT99887 NZ_CP027706:168952-169197 [Pseudomonas sp. CMR12a]
ATGCAAAGTATCCTGGCTGACAAAGCCGTCAGCGTATCTGAGTTGAAGAAGAATCCTTCAGCGGTATTGAACGGCGCTCA
AGGTGGCCCGGTGGCTGTGTTGAACCACAACCGGGTCATGGGCTACATGATTCCTGCCGAAGTTTTCGAAGCGTTGATGG
AGCGTTTGGACGATCTGGAACTGGCCGAGATCGTTCGGGCGCGTAGTCAGGAGACTCCCGTCCCGGTCAGTCTGGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References