Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2521041..2521275 Replicon chromosome
Accession NZ_CP027599
Organism Escherichia coli strain 97-3250

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2521171..2521274 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2521041..2521275 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7A06_RS13610 2517596..2518258 - 663 WP_000944256.1 exodeoxyribonuclease X -
C7A06_RS13615 2518282..2518938 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C7A06_RS13620 2519040..2519270 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C7A06_RS13625 2519409..2519783 + 375 WP_000204699.1 CopC domain-containing protein YobA -
C7A06_RS13630 2519787..2520659 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C7A06_RS13635 2520672..2521013 + 342 WP_000976492.1 YebY family protein -
- 2521041..2521275 - 235 - - Antitoxin
- 2521171..2521274 + 104 - - Toxin
C7A06_RS13640 2521406..2522481 - 1076 Protein_2523 phage integrase Arm DNA-binding domain-containing protein -
C7A06_RS13645 2522447..2522728 - 282 WP_001443927.1 excisionase -
C7A06_RS13650 2522835..2523023 - 189 WP_001356607.1 DUF1187 family protein -
- 2522839..2523017 + 179 NuclAT_1 - -
- 2522839..2523017 + 179 NuclAT_1 - -
- 2522839..2523017 + 179 NuclAT_1 - -
- 2522839..2523017 + 179 NuclAT_1 - -
C7A06_RS13655 2523016..2523210 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
C7A06_RS13660 2523267..2524076 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleG7' 2515539..2585189 69650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99711 NZ_CP027599:2521171-2521274 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT99711 NZ_CP027599:c2521275-2521041 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References