Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 99274..99545 Replicon chromosome
Accession NZ_CP027573
Organism Escherichia coli strain 2013C-4081

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 99404..99507 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 99274..99545 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A2F94_RS00490 95829..96491 - 663 WP_000944256.1 exodeoxyribonuclease X -
A2F94_RS00495 96515..97171 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
A2F94_RS00500 97273..97503 - 231 WP_000916763.1 DNA polymerase III subunit theta -
A2F94_RS00505 97642..98016 + 375 WP_000204699.1 CopC domain-containing protein YobA -
A2F94_RS00510 98020..98892 + 873 WP_000879274.1 copper homeostasis membrane protein CopD -
A2F94_RS00515 98905..99246 + 342 WP_000976492.1 YebY family protein -
- 99274..99545 - 272 - - Antitoxin
- 99404..99507 + 104 - - Toxin
A2F94_RS00520 99642..100298 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
A2F94_RS00525 100299..100490 - 192 WP_001296140.1 YebW family protein -
A2F94_RS00530 100595..100831 - 237 WP_001295499.1 DUF1480 family protein -
A2F94_RS00535 100949..102388 - 1440 WP_000057021.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T99472 NZ_CP027573:99404-99507 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT99472 NZ_CP027573:c99545-99274 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References