Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4057985..4058253 Replicon chromosome
Accession NZ_CP027452
Organism Escherichia coli strain 2014C-3338

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4058113..4058215 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4057985..4058253 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W71_RS20720 4054539..4055201 - 663 WP_000944256.1 exodeoxyribonuclease X -
C6W71_RS20725 4055225..4055881 - 657 WP_000011673.1 carbon-nitrogen hydrolase family protein -
C6W71_RS20730 4055983..4056213 - 231 WP_000916759.1 DNA polymerase III subunit theta -
C6W71_RS20735 4056352..4056725 + 374 Protein_3786 CopC domain-containing protein YobA -
C6W71_RS20740 4056729..4057601 + 873 WP_000879316.1 copper homeostasis membrane protein CopD -
C6W71_RS20745 4057614..4057955 + 342 WP_000976472.1 YebY family protein -
- 4057985..4058253 - 269 - - Antitoxin
- 4058113..4058215 + 103 - - Toxin
C6W71_RS20750 4058350..4059006 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
C6W71_RS20755 4059007..4059198 - 192 WP_001317886.1 YebW family protein -
C6W71_RS20760 4059303..4059539 - 237 WP_001295499.1 DUF1480 family protein -
C6W71_RS20765 4059657..4061097 - 1441 Protein_3792 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T98945 NZ_CP027452:4058113-4058215 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT98945 NZ_CP027452:c4058253-4057985 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References