Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1507878..1508149 Replicon chromosome
Accession NZ_CP027388
Organism Escherichia coli strain 2011C-4251

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1507916..1508019 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1507878..1508149 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6P70_RS08310 1505035..1506474 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C6P70_RS08315 1506592..1506828 + 237 WP_001295499.1 DUF1480 family protein -
C6P70_RS08320 1506933..1507124 + 192 WP_001296140.1 YebW family protein -
C6P70_RS08325 1507125..1507781 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 1507878..1508149 + 272 - - Antitoxin
- 1507916..1508019 - 104 - - Toxin
C6P70_RS08330 1508177..1508518 - 342 WP_000976472.1 YebY family protein -
C6P70_RS08335 1508531..1509403 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
C6P70_RS08340 1509407..1509781 - 375 WP_000204700.1 CopC domain-containing protein YobA -
C6P70_RS08345 1509920..1510150 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C6P70_RS08350 1510252..1510908 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C6P70_RS08355 1510932..1511594 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T98535 NZ_CP027388:c1508019-1507916 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT98535 NZ_CP027388:1507878-1508149 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References