Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1603362..1603596 | Replicon | chromosome |
| Accession | NZ_CP027338 | ||
| Organism | Escherichia coli strain 2014C-3051 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1603363..1603466 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1603362..1603596 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6N28_RS09235 | 1599740..1600567 | + | 828 | Protein_1690 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| C6N28_RS09240 | 1600560..1601369 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| C6N28_RS09245 | 1601426..1601620 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| C6N28_RS09250 | 1601613..1601801 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 1601619..1601797 | - | 179 | NuclAT_1 | - | - |
| - | 1601619..1601797 | - | 179 | NuclAT_1 | - | - |
| - | 1601619..1601797 | - | 179 | NuclAT_1 | - | - |
| - | 1601619..1601797 | - | 179 | NuclAT_1 | - | - |
| C6N28_RS09255 | 1601908..1602189 | + | 282 | WP_001443927.1 | excisionase | - |
| C6N28_RS09260 | 1602155..1603231 | + | 1077 | WP_106889283.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1603362..1603596 | + | 235 | - | - | Antitoxin |
| - | 1603363..1603466 | - | 104 | - | - | Toxin |
| C6N28_RS09265 | 1603624..1603965 | - | 342 | WP_000976492.1 | YebY family protein | - |
| C6N28_RS09270 | 1603978..1604850 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| C6N28_RS09275 | 1604854..1605228 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| C6N28_RS09280 | 1605367..1605597 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C6N28_RS09285 | 1605699..1606355 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| C6N28_RS09290 | 1606379..1607041 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 1549721..1609098 | 59377 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T98074 NZ_CP027338:c1603466-1603363 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT98074 NZ_CP027338:1603362-1603596 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
