Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 439825..440341 Replicon chromosome
Accession NZ_CP027218
Organism Pseudomonas sp. DTU12.3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C2E19_RS01940 Protein ID WP_129387364.1
Coordinates 440060..440341 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C2E19_RS01935 Protein ID WP_129387361.1
Coordinates 439825..440070 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2E19_RS01895 435000..435605 + 606 WP_129387339.1 adenylyl-sulfate kinase -
C2E19_RS01900 435602..436387 + 786 WP_129387342.1 aspartyl/asparaginyl beta-hydroxylase domain-containing protein -
C2E19_RS01905 436375..437319 + 945 WP_129387345.1 sulfotransferase family protein -
C2E19_RS01910 437400..438158 - 759 WP_129387349.1 slipin family protein -
C2E19_RS01915 438161..438712 - 552 WP_129387352.1 serine protease -
C2E19_RS01920 438866..439327 + 462 WP_053116446.1 YbaK/EbsC family protein -
C2E19_RS01930 439485..439730 + 246 WP_129387358.1 DUF2789 domain-containing protein -
C2E19_RS01935 439825..440070 + 246 WP_129387361.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C2E19_RS01940 440060..440341 + 282 WP_129387364.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C2E19_RS01945 440485..440913 + 429 WP_129387366.1 winged helix DNA-binding protein -
C2E19_RS01950 440910..442973 + 2064 WP_129387368.1 FUSC family protein -
C2E19_RS01955 442970..443179 + 210 WP_007917703.1 DUF1656 domain-containing protein -
C2E19_RS01960 443176..444078 + 903 WP_129387370.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10814.67 Da        Isoelectric Point: 10.4241

>T97634 WP_129387364.1 NZ_CP027218:440060-440341 [Pseudomonas sp. DTU12.3]
MTFKLEFLPSAYKEWNKLGHTLREQFKKKLGERLDLPRVSADALHGMPDCYKIKLKASGYRLVYQVIDERVVVSVVAVGK
RERSSVYENAKKR

Download         Length: 282 bp

>T97634 NZ_CP027218:440060-440341 [Pseudomonas sp. DTU12.3]
ATGACCTTTAAGCTCGAATTTCTGCCATCTGCTTACAAAGAATGGAACAAGTTGGGTCATACACTGCGAGAGCAATTCAA
AAAGAAGCTGGGCGAGCGGTTGGATCTGCCCAGAGTATCTGCGGATGCTCTGCATGGGATGCCGGATTGTTACAAAATCA
AACTGAAGGCTTCCGGCTACCGTTTGGTTTATCAAGTGATTGACGAGCGCGTGGTTGTTTCCGTCGTTGCGGTCGGCAAA
CGTGAACGCAGCAGCGTTTATGAGAATGCTAAAAAGCGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8708.97 Da        Isoelectric Point: 4.4830

>AT97634 WP_129387361.1 NZ_CP027218:439825-440070 [Pseudomonas sp. DTU12.3]
MQSVLADMAVSVSELKKNPSAVLSGAHGGAVAVLNHNRVMGYMVPADVYEAMMERLDDLDLAEIVRARSHETPISVSLDD
L

Download         Length: 246 bp

>AT97634 NZ_CP027218:439825-440070 [Pseudomonas sp. DTU12.3]
ATGCAAAGTGTTTTGGCCGATATGGCTGTCAGTGTTTCCGAATTAAAGAAAAACCCTTCTGCAGTCCTGAGCGGCGCACA
TGGCGGAGCTGTGGCGGTTCTCAACCACAATCGCGTTATGGGCTACATGGTTCCAGCGGATGTGTACGAAGCAATGATGG
AGCGGTTAGATGATCTGGACCTTGCTGAAATCGTTCGCGCCCGCAGCCATGAAACGCCAATTTCGGTAAGCCTGGATGAC
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References